Joseph E Zerwekh

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. ncbi request reprint Nutrition and renal stone disease in space
    Joseph E Zerwekh
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Nutrition 18:857-63. 2002
  2. doi request reprint Bone disease and hypercalciuria in children
    Joseph E Zerwekh
    Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 8885, USA
    Pediatr Nephrol 25:395-401. 2010
  3. pmc Biochemical and histological assessment of alkali therapy during high animal protein intake in the rat
    Joseph E Zerwekh
    Department of Internal Medicine, Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, Dallas, TX 75390 8885, USA
    Bone 45:1004-9. 2009
  4. ncbi request reprint Blood biomarkers of vitamin D status
    Joseph E Zerwekh
    Charles and Jane Pak Center for Mineral Metabolism and Clinical Research and Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390 8885, USA
    Am J Clin Nutr 87:1087S-91S. 2008
  5. pmc Bone disease and idiopathic hypercalciuria
    Joseph E Zerwekh
    Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390 8885, USA
    Semin Nephrol 28:133-42. 2008
  6. ncbi request reprint Reduction of renal stone risk by potassium-magnesium citrate during 5 weeks of bed rest
    Joseph E Zerwekh
    Center for Mineral Metabolism and Clinical Research, and the Department of Physical Medicine and Rehabilitation, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Urol 177:2179-84. 2007
  7. ncbi request reprint Pathogenesis of hypercalciuric nephrolithiasis
    Joseph E Zerwekh
    Department of Internal Medicine, Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390 8885, USA
    Endocrinol Metab Clin North Am 31:869-84. 2002
  8. ncbi request reprint The measurement of vitamin D: analytical aspects
    Joseph E Zerwekh
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390 8885, USA
    Ann Clin Biochem 41:272-81. 2004
  9. doi request reprint Intestinal hyperabsorption of calcium and low bone turnover in hypercalciuric postmenopausal osteoporosis
    Clarita V Odvina
    Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 8885, USA
    Urol Res 36:233-9. 2008
  10. ncbi request reprint Effect of high protein diet on stone-forming propensity and bone loss in rats
    Jamshid Amanzadeh
    Center for Mineral Metabolism and Clinical Research and Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8885, USA
    Kidney Int 64:2142-9. 2003

Detail Information

Publications21

  1. ncbi request reprint Nutrition and renal stone disease in space
    Joseph E Zerwekh
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Nutrition 18:857-63. 2002
    ..Success in reducing the risk for stone formation in astronauts would also be of potential major benefit to the estimated 20 million Americans with nephrolithiasis...
  2. doi request reprint Bone disease and hypercalciuria in children
    Joseph E Zerwekh
    Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 8885, USA
    Pediatr Nephrol 25:395-401. 2010
    ..Thus, a better understanding of bone loss in children with IH is warranted...
  3. pmc Biochemical and histological assessment of alkali therapy during high animal protein intake in the rat
    Joseph E Zerwekh
    Department of Internal Medicine, Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, Dallas, TX 75390 8885, USA
    Bone 45:1004-9. 2009
    ..In this animal model of high dietary animal protein intake, the major skeletal effect of alkali therapy is to reduce bone resorption, with little or no effect on bone formation...
  4. ncbi request reprint Blood biomarkers of vitamin D status
    Joseph E Zerwekh
    Charles and Jane Pak Center for Mineral Metabolism and Clinical Research and Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390 8885, USA
    Am J Clin Nutr 87:1087S-91S. 2008
    ....
  5. pmc Bone disease and idiopathic hypercalciuria
    Joseph E Zerwekh
    Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390 8885, USA
    Semin Nephrol 28:133-42. 2008
    ..Available evidence suggests that potential mechanisms may be dependent in large part to genetic, metabolic, and nutritional causes of hypercalciuria and bone loss in patients with IH...
  6. ncbi request reprint Reduction of renal stone risk by potassium-magnesium citrate during 5 weeks of bed rest
    Joseph E Zerwekh
    Center for Mineral Metabolism and Clinical Research, and the Department of Physical Medicine and Rehabilitation, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Urol 177:2179-84. 2007
    ..This study was performed to evaluate the efficacy of potassium alkali as potassium-magnesium citrate in reducing renal stone risk and bone turnover...
  7. ncbi request reprint Pathogenesis of hypercalciuric nephrolithiasis
    Joseph E Zerwekh
    Department of Internal Medicine, Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390 8885, USA
    Endocrinol Metab Clin North Am 31:869-84. 2002
    ..Such studies have disclosed that hypercalciuria is probably polygenic in nature and will require a concerted effort to better understand the defects while attempting to develop gene-specific countermeasures...
  8. ncbi request reprint The measurement of vitamin D: analytical aspects
    Joseph E Zerwekh
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390 8885, USA
    Ann Clin Biochem 41:272-81. 2004
    ..This review will consider when vitamin D measurements should be undertaken and how best to perform such assays...
  9. doi request reprint Intestinal hyperabsorption of calcium and low bone turnover in hypercalciuric postmenopausal osteoporosis
    Clarita V Odvina
    Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 8885, USA
    Urol Res 36:233-9. 2008
    ....
  10. ncbi request reprint Effect of high protein diet on stone-forming propensity and bone loss in rats
    Jamshid Amanzadeh
    Center for Mineral Metabolism and Clinical Research and Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8885, USA
    Kidney Int 64:2142-9. 2003
    ..The purpose of this study was to create an animal model of animal protein excess and to evaluate the response of kidney and bone to the dietary protein load...
  11. ncbi request reprint Severely suppressed bone turnover: a potential complication of alendronate therapy
    Clarita V Odvina
    Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8885, USA
    J Clin Endocrinol Metab 90:1294-301. 2005
    ..Our observations emphasize the need for increased awareness and monitoring for the potential development of excessive suppression of bone turnover during long-term alendronate therapy...
  12. doi request reprint Defining hypercalciuria in nephrolithiasis
    Charles Y C Pak
    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8885, USA
    Kidney Int 80:777-82. 2011
    ..When dietary variables are controlled, the classic definition of hypercalciuria of nephrolithiasis appears valid...
  13. doi request reprint Unusual mid-shaft fractures during long-term bisphosphonate therapy
    Clarita V Odvina
    Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, Dallas, TX 75390 8885, USA
    Clin Endocrinol (Oxf) 72:161-8. 2010
    ..Although existing evidence supports a good safety profile, there is concern that chronic administration of these agents could result in severe suppression of bone turnover with increased risk of nonvertebral fractures...
  14. pmc Biphasic and dosage-dependent regulation of osteoclastogenesis by β-catenin
    Wei Wei
    Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9041, USA
    Mol Cell Biol 31:4706-19. 2011
    ..Importantly, these findings suggest that Wnt activation is a more effective treatment for skeletal fragility than previously recognized that confers dual anabolic and anti-catabolic benefits...
  15. ncbi request reprint Aromatase deficiency causes altered expression of molecules critical for calcium reabsorption in the kidneys of female mice *
    Orhan K Oz
    Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9153, USA
    J Bone Miner Res 22:1893-902. 2007
    ..ArKO mice have hypercalciuria and lower levels of calcium transport proteins, whereas levels of the klotho protein are elevated. Thus, estrogen deficiency is sufficient to cause altered renal calcium handling...
  16. pmc Inhibition of osteoclast formation and function by bicarbonate: role of soluble adenylyl cyclase
    Weidong Geng
    Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, University of Texas, Southwestern Medical Center at Dallas, Dallas, TX 75390 8885, USA
    J Cell Physiol 220:332-40. 2009
    ..This HCO(3)(-) effect on BV/TV was blocked by 2-hydroxyestradiol. In summary, sAC mediates the inhibition of osteoclast function by HCO(3)(-), by acting as a HCO(3)(-) sensor...
  17. pmc Variability in urinary oxalate measurements between six international laboratories
    Naim M Maalouf
    Department of Internal Medicine, University of Texas, Southwestern Medical Center, Dallas, TX, USA
    Nephrol Dial Transplant 26:3954-9. 2011
    ..Hyperoxaluria is a major risk factor for kidney stone formation. Although urinary oxalate measurement is part of all basic stone risk assessment, there is no standardized method for this measurement...
  18. pmc Comparison of semi-empirical and computer derived methods for estimating urinary saturation of brushite
    Charles Y C Pak
    Center for Mineral Metabolism and Clinical Research, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Urol 181:1423-8. 2009
    ..To attempt resolution the supersaturation index according to the Joint Expert Speciation System and the relative saturation ratio according to Equil 2 were compared with the semi-empirically derived concentration-to-product ratio...
  19. ncbi request reprint Estrogen and androgen play distinct roles in bone turnover in male mice before and after reaching sexual maturity
    Joseph E Zerwekh
    Bone 40:553. 2007
  20. ncbi request reprint Effect of subcutaneous leptin replacement therapy on bone metabolism in patients with generalized lipodystrophy
    Vinaya Simha
    Division of Nutrition and Metabolic Diseases, Center for Human Nutrition, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Clin Endocrinol Metab 87:4942-5. 2002
    ..Our preliminary data suggest that sc leptin replacement in hypoleptinemic patients with generalized lipodystrophy has no effect on the mature adult skeleton...
  21. ncbi request reprint Recovery from skeletal fluorosis (an enigmatic, American case)
    Etah S Kurland
    Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA
    J Bone Miner Res 22:163-70. 2007
    ..Nearly a decade of detailed follow-up documented considerable correction of the disorder after removal of the putative source of fluoride (toothpaste)...