Kai Zeng

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. ncbi Compound tests for the detection of hitchhiking under positive selection
    Kai Zeng
    State Key Laboratory of Biocontrol and Key Laboratory of Gene Engineering of the Ministry of Education, Sun Yat Sen University, Guangzhou, China
    Mol Biol Evol 24:1898-908. 2007
  2. pmc Statistical tests for detecting positive selection by utilizing high-frequency variants
    Kai Zeng
    State Key Laboratory of Biocontrol, Ministry of Education, Sun Yat Sen University, Guangzhou, China
    Genetics 174:1431-9. 2006
  3. ncbi Comparisons of site- and haplotype-frequency methods for detecting positive selection
    Kai Zeng
    State Key Laboratory of Biocontrol and Key Laboratory of Gene Engineering of the Ministry of Education, Sun Yat Sen University, Guangzhou, China
    Mol Biol Evol 24:1562-74. 2007
  4. ncbi Population genetics of speciation in nonmodel organisms: I. Ancestral polymorphism in mangroves
    Renchao Zhou
    State Key Laboratory of Biocontrol and Key Laboratory of Gene Engineering of the Ministry of Education, Sun Yat Sen University, Guangzhou, China
    Mol Biol Evol 24:2746-54. 2007
  5. pmc An ancient balanced polymorphism in a regulatory region of human major histocompatibility complex is retained in Chinese minorities but lost worldwide
    Xiaoyi Liu
    State Key Laboratory for Biocontrol, Department of Biochemistry, Key Laboratory of Genetic Engineering of the Ministry of Education, College of Life Sciences, Sun Yat Sen Zhongshan University, Guangzhou, China
    Am J Hum Genet 78:393-400. 2006
  6. ncbi Molecular phylogenetic analysis of mangroves: independent evolutionary origins of vivipary and salt secretion
    Suhua Shi
    State Key Laboratory for Biocontrol, Key Laboratory of Gene Engineering of the Ministry of Education, School of Life Sciences, Sun Yatsen Zhongshan University, Guangzhou 510275, China
    Mol Phylogenet Evol 34:159-66. 2005
  7. ncbi Cone-beam mammo-computed tomography from data along two tilting arcs
    Kai Zeng
    CT Micro CT Laboratory, Department of Radiology, University of Iowa, Iowa City, Iowa 52242, USA
    Med Phys 33:3621-33. 2006
  8. ncbi Digital tomosynthesis aided by low-resolution exact computed tomography
    Kai Zeng
    VT WFU School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA
    J Comput Assist Tomogr 31:976-83. 2007
  9. pmc Adaptive evolution of newly emerged micro-RNA genes in Drosophila
    Jian Lu
    Department of Ecology and Evolution, University of Chicago, USA
    Mol Biol Evol 25:929-38. 2008

Collaborators

Detail Information

Publications9

  1. ncbi Compound tests for the detection of hitchhiking under positive selection
    Kai Zeng
    State Key Laboratory of Biocontrol and Key Laboratory of Gene Engineering of the Ministry of Education, Sun Yat Sen University, Guangzhou, China
    Mol Biol Evol 24:1898-908. 2007
    ..Furthermore, the DHEW test, similar to DH, is also relatively insensitive to background selection and demography. The HEW test, on the other hand, tends to be somewhat less conservative than DH and DHEW in some cases...
  2. pmc Statistical tests for detecting positive selection by utilizing high-frequency variants
    Kai Zeng
    State Key Laboratory of Biocontrol, Ministry of Education, Sun Yat Sen University, Guangzhou, China
    Genetics 174:1431-9. 2006
    ..We thus propose a joint test, referred to as the DH test. Simulations indicate that DH is indeed sensitive primarily to directional selection and no other driving forces...
  3. ncbi Comparisons of site- and haplotype-frequency methods for detecting positive selection
    Kai Zeng
    State Key Laboratory of Biocontrol and Key Laboratory of Gene Engineering of the Ministry of Education, Sun Yat Sen University, Guangzhou, China
    Mol Biol Evol 24:1562-74. 2007
    ..In the companion paper (Zeng K, Shi S, Wu C-I, in preparation), we use the EW test to devise 2 compound tests, which are more powerful in detecting positive selection than DH, but are also relatively insensitive to demography...
  4. ncbi Population genetics of speciation in nonmodel organisms: I. Ancestral polymorphism in mangroves
    Renchao Zhou
    State Key Laboratory of Biocontrol and Key Laboratory of Gene Engineering of the Ministry of Education, Sun Yat Sen University, Guangzhou, China
    Mol Biol Evol 24:2746-54. 2007
    ..This population structure would give rise to high level of polymorphism across species range. This approach of studying the speciation history by genomic means should be applicable to nonmodel organisms...
  5. pmc An ancient balanced polymorphism in a regulatory region of human major histocompatibility complex is retained in Chinese minorities but lost worldwide
    Xiaoyi Liu
    State Key Laboratory for Biocontrol, Department of Biochemistry, Key Laboratory of Genetic Engineering of the Ministry of Education, College of Life Sciences, Sun Yat Sen Zhongshan University, Guangzhou, China
    Am J Hum Genet 78:393-400. 2006
    ..As suspected, some ancient balanced polymorphisms, lost in major populations, still exist in isolated ethnicities. These isolated populations may thus contribute disproportionately to the total diversity of modern humans...
  6. ncbi Molecular phylogenetic analysis of mangroves: independent evolutionary origins of vivipary and salt secretion
    Suhua Shi
    State Key Laboratory for Biocontrol, Key Laboratory of Gene Engineering of the Ministry of Education, School of Life Sciences, Sun Yatsen Zhongshan University, Guangzhou 510275, China
    Mol Phylogenet Evol 34:159-66. 2005
    ..For each character, its ancestral state in the phylogeny was estimated by the maximum likelihood method. Overall evidence is in favor of a multiple origin for both vivipary and salt secretion in mangroves...
  7. ncbi Cone-beam mammo-computed tomography from data along two tilting arcs
    Kai Zeng
    CT Micro CT Laboratory, Department of Radiology, University of Iowa, Iowa City, Iowa 52242, USA
    Med Phys 33:3621-33. 2006
    ..We also demonstrate the system performance and clinical utility of the proposed technique in numerical simulations...
  8. ncbi Digital tomosynthesis aided by low-resolution exact computed tomography
    Kai Zeng
    VT WFU School of Biomedical Engineering and Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA
    J Comput Assist Tomogr 31:976-83. 2007
    ..The results show that images obtained by our approach are clearly better than those obtained without such a CT scan...
  9. pmc Adaptive evolution of newly emerged micro-RNA genes in Drosophila
    Jian Lu
    Department of Ecology and Evolution, University of Chicago, USA
    Mol Biol Evol 25:929-38. 2008
    ..melanogaster is indicative of hitchhiking under positive selection. Thus, a large number of adaptive changes over a long period of time may be essential for the evolution of newly emerged miRNA genes...