Affiliation: University of Oklahoma Health Sciences Center
Budda S, Zenewicz L. IL-22 deficiency increases CD4 T cell responses to mucosal immunization. Vaccine. 2018;36:3694-3700 pubmed publisher
..The broad-applicability of this proposed approach would allow for improvement of many existing mucosal vaccine regimens and have positive implications in the development of more efficacious mucosal vaccines. ..
Seshadri S, Pope R, Zenewicz L. Glucocorticoids Inhibit Group 3 Innate Lymphocyte IL-22 Production. J Immunol. 2018;201:1267-1274 pubmed publisher
..These findings implicate NF-?B as a regulator of IL-22 in ILC3s and likely have repercussions on GC treatment of IBD patients. ..
Budda S, Girton A, Henderson J, Zenewicz L. Transcription Factor HIF-1? Controls Expression of the Cytokine IL-22 in CD4 T Cells. J Immunol. 2016;197:2646-52 pubmed publisher
..These findings have implications on the regulation of Il22 gene expression and the presence of the cytokine in different inflammatory environments. ..