Research Topics
| J A ZellSummaryAffiliation: University of California Country: USA Publications
| Collaborators
|
Detail Information
Publications
Role of obesity in a randomized placebo-controlled trial of difluoromethylornithine (DFMO) + sulindac for the prevention of sporadic colorectal adenomasJason A Zell
Chao Family Comprehensive Cancer Center, University of California, Irvine, CA 92697, USA
Cancer Causes Control 23:1739-44. 2012..Obesity is associated with risk of colorectal adenoma and colorectal cancer. This study investigates how obesity influences risk of recurrent adenoma after prolonged treatment with DFMO + sulindac versus placebo...- Review of epidemiologic data on the debate over smokeless tobacco's role in harm reductionDavid S Timberlake
Program in Public Health, University of California, Irvine, Irvine, CA 92697, USA
BMC Med 7:61. 2009..See associated research article by Lee and Hamling: http://www.biomedcentral.com/1741-7015/7/36... - Nonsteroidal anti-inflammatory drugs: effects on mortality after colorectal cancer diagnosisJason A Zell
Genetic Epidemiology Research Institute and Department of Epidemiology, University of California at Irvine, Irvine, California 92697 7550, USA
Cancer 115:5662-71. 2009..The authors investigated the association between prediagnosis NSAID use and mortality after CRC diagnosis among women in the California Teachers Study cohort... - Associations of a polymorphism in the ornithine decarboxylase gene with colorectal cancer survivalJason A Zell
Department of Epidemiology, University of California, Irvine, California 92697, USA
Clin Cancer Res 15:6208-16. 2009..We examined associations of the +316 ODC1 single nucleotide polymorphism (SNP) with colorectal cancer-specific survival among colorectal cancer cases, and then investigated its functional significance in colon cancer cells... 
Differential effects of wine consumption on colorectal cancer outcomes based on family history of the diseaseJason A Zell
Genetic Epidemiology Research Institute, University of California UC Irvine, Irvine, CA 92697, USA
Nutr Cancer 59:36-45. 2007..50, 95% confidence interval = 0.25-0.99). Our findings implicate favorable effects of wine consumption on stage at presentation and survival in CRC, selectively among familial CRC cases...- Survival improvements for advanced stage nonbronchioloalveolar carcinoma-type nonsmall cell lung cancer cases with ipsilateral intrapulmonary nodulesJason A Zell
Division of Hematology Oncology, Department of Medicine, Chao Family Comprehensive Cancer Center, University of California at Irvine School of Medicine, Irvine, California 92697, USA
Cancer 112:136-43. 2008..However, it is not known whether these differences are observed in patients with non-BAC NSCLC... - Validation of the proposed International Association for the Study of Lung Cancer non-small cell lung cancer staging system revisions for advanced bronchioloalveolar carcinoma using data from the California Cancer RegistryJason A Zell
Genetic Epidemiology Research Institute, Department of Epidemiology, University of California Irvine, Irvine, California, USA
J Thorac Oncol 2:1078-85. 2007..We set out to validate this staging system for bronchioloalveolar carcinoma (BAC) cases using data from the California Cancer Registry (CCR)... 
Survival for patients with invasive cutaneous melanoma among ethnic groups: the effects of socioeconomic status and treatmentJason A Zell
Division of Hematology Oncology, Department of Internal Medicine, Chao Family Comprehensive Cancer Center, University of California, Irvine 92697, USA
J Clin Oncol 26:66-75. 2008..We set out to determine this by using the large, population-based California Cancer Registry (CCR) database as a model...- Risk of cardiovascular events in a randomized placebo-controlled, double-blind trial of difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomasJason A Zell
Chao Family Comprehensive Cancer Center, University of California, Irvine, California, USA
Cancer Prev Res (Phila) 2:209-12. 2009..These results have implications for future NSAID-based cancer prevention clinical trials... - Prognostic impact of human epidermal growth factor-like receptor 2 and hormone receptor status in inflammatory breast cancer (IBC): analysis of 2,014 IBC patient cases from the California Cancer RegistryJason A Zell
Department of Epidemiology, Genetic Epidemiology Research Institute, School of Medicine, University of California Irvine, Irvine, CA 92697, USA
Breast Cancer Res 11:R9. 2009.... - Survival after colorectal cancer diagnosis is associated with colorectal cancer family historyJason A Zell
Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, Department of Medicine, University of California, Irvine, Irvine, CA 92697, USA
Cancer Epidemiol Biomarkers Prev 17:3134-40. 2008..Our population-based analysis investigates whether familial CRC cases exhibit improved survival compared with sporadic CRC cases... - Long-term survival differences for bronchiolo-alveolar carcinoma patients with ipsilateral intrapulmonary metastasis at diagnosisJ A Zell
Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, Genetic Epidemiology Research Institute, Department of Medicine, School of Medicine, University of California Irvine, USA
Ann Oncol 17:1255-62. 2006..It has been suggested that the current staging system does not accurately reflect survival outcomes for advanced bronchiolo-alveolar carcinoma (BAC) patients... - Epidemiology of bronchioloalveolar carcinoma: improvement in survival after release of the 1999 WHO classification of lung tumorsJason A Zell
The Chao Family Comprehensive Cancer Center, Division of Hematology, Department of Medicine, University of California, Irvine, CA, USA
J Clin Oncol 23:8396-405. 2005..Classification changes for bronchioloalveolar carcinoma (BAC) by the WHO in May 1999 narrowed its definition. This study was undertaken in an attempt to characterize the impact of these changes on the epidemiology of BAC... - Race, socioeconomic status, treatment, and survival time among pancreatic cancer cases in CaliforniaJason A Zell
Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, University of California, Irvine Medical Center, 101 The City Drive South, Orange, CA 92868, USA
Cancer Epidemiol Biomarkers Prev 16:546-52. 2007..We set out to determine this using the large, population-based California Cancer Registry (CCR) database as a model... - Risk and risk reduction involving arginine intake and meat consumption in colorectal tumorigenesis and survivalJason A Zell
Genetic Epidemiology Research Institute, University of California Irvine, Irvine, CA 92697 7550, USA
Int J Cancer 120:459-68. 2007..Our results suggest important roles for arginine and meat consumption in CRC pathogenesis, and have implications for CRC prevention... - Meat consumption, nonsteroidal anti-inflammatory drug use, and mortality among colorectal cancer patients in the California Teachers StudyJason A Zell
Genetic Epidemiology Research Institute, Department of Epidemiology, University of California at Irvine, 92697, USA
Cancer Prev Res (Phila) 3:865-75. 2010..These findings have implications for CRC survivorship and tertiary CRC prevention... - Precore mutant hepatitis B reactivation after treatment with CHOP-rituximabJason A Zell
Division of Hematology Oncology, Department of Medicine, College of Medicine, University of California Irvine, Irvine, CA, USA
Anticancer Drugs 16:83-5. 2005..Hepatitis B reactivation in patients receiving rituxmab-based chemotherapy is reviewed and the role of precore mutant virus strains resulting in fatal complications is discussed... - Ornithine decarboxylase-1 polymorphism, chemoprevention with eflornithine and sulindac, and outcomes among colorectal adenoma patientsJason A Zell
Chao Family Comprehensive Cancer Center, Department of Epidemiology, University of California Irvine, 224 Irvine Hall, Irvine, CA 92697, USA
J Natl Cancer Inst 102:1513-6. 2010..038). Excess ototoxicity was observed among ODC1 AA patients receiving treatment, but the interaction of genotype and treatment on ototoxicity was not statistically significant (P = .45)... - Neoplastic fever: a neglected paraneoplastic syndromeJason A Zell
Division of Hematology Oncology, Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, Orange, CA 92868, USA
Support Care Cancer 13:870-7. 2005..In addition, naproxen and other nonsteroidal anti-inflammatory drugs have been effective in the management of neoplastic fever and offer a significant palliative benefit for the patient... - Validation study of the proposed IASLC staging revisions of the T4 and M non-small cell lung cancer descriptors using data from 23,583 patients in the California Cancer RegistrySai Hong Ignatius Ou
Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, Department of Medicine, University of Irvine Medical Center, Orange, California 92868, USA
J Thorac Oncol 3:216-27. 2008.... - Role of dietary polyamines in a phase III clinical trial of difluoromethylornithine (DFMO) and sulindac for prevention of sporadic colorectal adenomasK P Raj
Chao Family Comprehensive Cancer Center, University of California, Irvine, CA 92697, USA
Br J Cancer 108:512-8. 2013..Polyamines are synthesised endogenously and obtained from dietary sources. Here we investigate dietary polyamine intake and outcomes in the DFMO+sulindac colorectal adenoma prevention trial... - Misclassification of bronchioloalveolar carcinoma with cytologic diagnosis of lung cancerDan J Raz
Department of Surgery, Division of Cardiothoracic Surgery and the UCSF Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94131, USA
J Thorac Oncol 1:943-8. 2006..The aims of this study were to calculate the sensitivity and specificity of cytologic diagnosis of BAC and to estimate the misclassification of BAC as other subtypes of NSCLC... - Effects of socioeconomic status and treatment disparities in colorectal cancer survivalHoa Le
Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, School of Medicine, University of California at Irvine, Irvine, CA 92697, USA
Cancer Epidemiol Biomarkers Prev 17:1950-62. 2008..We set out to determine this using data from the large, population-based California Cancer Registry database... - Korean ethnicity as compared with white ethnicity is an independent favorable prognostic factor for overall survival in non-small cell lung cancer before and after the oral epidermal growth factor receptor tyrosine kinase inhibitor eraMyung Ju Ahn
Division of Hematology Oncology, Department of Internal Medicine, Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, 101 The City Drive, Bldg 56, Rt 81, Rm 241, Orange, CA 92868, USA
J Thorac Oncol 5:1185-96. 2010..We have previously demonstrated, using a regional California Cancer Registry database, that Asian ethnicity is an independent favorable prognostic factor for overall survival (OS) in non-small cell lung cancer (NSCLC)... - A population-based, descriptive analysis of malignant intraductal papillary mucinous neoplasms of the pancreasHoa Le
Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, School of Medicine, University of California, Irvine, CA 92697, USA
Cancer Epidemiol Biomarkers Prev 17:2737-41. 2008..We set out to do a population-based analysis of malignant IPMNs compared with other pancreatic subtypes to better delineate its characteristics and explore implications for prevention and management... - Low socioeconomic status is a poor prognostic factor for survival in stage I nonsmall cell lung cancer and is independent of surgical treatment, race, and marital statusS H Ignatius Ou
Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, Department of Medicine, University of California Irvine Medical Center, Orange, CA 92868 3298, USA
Cancer 112:2011-20. 2008..In this study, the authors investigated the role of SES in this survival disparity among patients with stage I NSCLC... - Survival of distinct Asian groups among colorectal cancer cases in CaliforniaHoa Le
Division of Hematology Oncology, Chao Family Comprehensive Cancer Center, University of California at Irvine, Irvine, California, USA
Cancer 115:259-70. 2009..In the current study, the authors attempted to determine differences using data from the large, population-based California Cancer Registry (CCR)... - Natural history of stage I non-small cell lung cancer: implications for early detectionDan J Raz
University of California, San Francisco, 513 Parnassus Ave, S 321, San Francisco, CA 94131, USA
Chest 132:193-9. 2007..Our hypothesis is that long-term survival in patients with untreated stage I non-small cell lung cancer (NSCLC) is uncommon... - Epidemiology of nasopharyngeal carcinoma in the United States: improved survival of Chinese patients within the keratinizing squamous cell carcinoma histologyS Hi Ou
Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, Department of Medicine, School of Medicine, University of California, Irvine, USA
Ann Oncol 18:29-35. 2007..This study examined potential survival differences among nasopharyngeal carcinoma (NPC) patients from various ethnicities in the United States... - Prognostic significance of the number of lymph nodes removed at lobectomy in stage IA non-small cell lung cancerSai Hong Ignatius Ou
Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, Department of Medicine, University of California Irvine Medical Center, Orange, CA 92868 3298, USA
J Thorac Oncol 3:880-6. 2008..We investigated whether the number of lymph nodes removed influences survival in stage IA NSCLC patients who underwent lobectomy... - Prognostic factors for survival of stage I nonsmall cell lung cancer patients : a population-based analysis of 19,702 stage I patients in the California Cancer Registry from 1989 to 2003S H Ignatius Ou
Division of Hematology Oncology, Department of Medicine, Chao Family Comprehensive Cancer Center, Orange, California 92868, USA
Cancer 110:1532-41. 2007.... - A comparison study of clinicopathologic characteristics of Southern California Asian American Non-small Cell Lung Cancer (NSCLC) patients by smoking statusSai Hong Ignatius Ou
Division of Hematology Oncology, Department of Medicine, Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, Orange, California 92868 3298, USA
J Thorac Oncol 5:158-68. 2010..However, Asian ethnicity represents a diverse and heterogeneous population. In this report, we compared the clinicopathologic characteristics of Asian American NSCLC patient subgroups by smoking status... - Primary signet-ring carcinoma (SRC) of the lung: a population-based epidemiologic study of 262 cases with comparison to adenocarcinoma of the lungSai Hong Ignatius Ou
Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, Department of Medicine, University of California, Irvine Medical Center, Orange, California 92868 3298, USA
J Thorac Oncol 5:420-7. 2010..We investigated the clinicopathologic features and survival outcome of primary signet-ring carcinoma (SRC) of the lung with comparison to adenocarcinoma of the lung... - Risk of a second breast cancer associated with hormone-receptor and HER2/neu status of the first breast cancerLeona Bessonova
Department of Epidemiology, University of California Irvine, Irvine, CA 92697, USA
Cancer Epidemiol Biomarkers Prev 20:389-96. 2011..Hormone-receptor (HR) and HER2/neu-receptor (HER2) status of breast tumors are important indicators for targeted therapies. We examine the association of receptor status and risk for a second breast cancer... - Prognostic significance of the non-size-based AJCC T2 descriptors: visceral pleura invasion, hilar atelectasis, or obstructive pneumonitis in stage IB non-small cell lung cancer is dependent on tumor sizeSai Hong Ignatius Ou
Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, Department of Medicine, University of California Irvine Medical Center, Orange, CA 92868 3298, USA
Chest 133:662-9. 2008..The T2 descriptor for staging non-small cell lung cancer (NSCLC) contains several non-size-based criteria. It remains unknown whether the prognostic significance of these non-size-based criteria is dependent on tumor size... - Carcinoma NOS is a common histologic diagnosis and is increasing in proportion among non-small cell lung cancer histologiesSai Hong Ignatius Ou
Division of Hematology Oncology, Department of Medicine, Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, Orange, California, USA
J Thorac Oncol 4:1202-11. 2009..We investigated whether the distribution of carcinoma NOS (not otherwise specified) among NSCLC cases in California have changed over time and determined the prognostic significance of carcinoma NOS... - Prognostic factors for survival in extensive stage small cell lung cancer (ED-SCLC): the importance of smoking history, socioeconomic and marital statuses, and ethnicitySai Hong Ignatius Ou
Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, Department of Medicine, University of California Irvine Medical Center, Orange, California, USA
J Thorac Oncol 4:37-43. 2009.... - The applicability of the proposed IASLC staging revisions to small cell lung cancer (SCLC) with comparison to the current UICC 6th TNM EditionSai Hong Ignatius Ou
Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, Department of Medicine, University of California Irvine Medical Center, Orange, CA 92868 3298, USA
J Thorac Oncol 4:300-10. 2009..We examined the impact of the proposed Internal Association for the Study of Lung Cancer (IASLC) tumor, node, metastasis (TNM) and stage grouping revisions on staging and survival outcome of small cell lung cancer (SCLC)... - Hypertension, antihypertensive medication use, and breast cancer risk in the California Teachers Study cohortJoan A Largent
Department of Epidemiology, College of Health Sciences, University of California Irvine, Irvine, CA 92697 7555, USA
Cancer Causes Control 21:1615-24. 2010..We investigated the association between hypertension, antihypertensive (AH) medication use, and breast cancer in a large prospective study, the California Teachers Study (CTS)... - Need for a new treatment strategy: leptomeningeal carcinomatosis from gastric cancerKavitha P Raj
Department of Medicine, Chao Family Comprehensive Cancer Center, University of California, Irvine, 92868, USA
Anticancer Drugs 20:301-4. 2009..Our patient not only had an excellent tumor response to this novel approach, but also had a prolonged overall survival of 13 months, which is unusual for LMC from gastric cancer... - Tumor subsite location within the colon is prognostic for survival after colon cancer diagnosisCharlie M Wray
College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California, USA
Dis Colon Rectum 52:1359-66. 2009..We examined survival by colon cancer subsite location by use of data from the California Cancer Registry... - Asian ethnicity is a favorable prognostic factor for overall survival in non-small cell lung cancer (NSCLC) and is independent of smoking statusSai Hong Ignatius Ou
Chao Family Comprehensive Cancer Center, Division of Hematology Oncology, Department of Medicine, University of Irvine Medical Center, Orange, California 92868 3298, USA
J Thorac Oncol 4:1083-93. 2009..Many Asian NSCLC patients were never-smokers, and never-smokers had improved survival than ever-smokers. We investigated whether Asian ethnicity is a favorable prognostic factor independent of smoking status... - Analysis of prognostic factors in Ewing sarcoma using a population-based cancer registryJoe Lee
Department of Orthopaedic Surgery, University of California at Irvine, Irvine, California 92697 7550, USA
Cancer 116:1964-73. 2010..By using data from a large, population-based cancer registry, the authors designed the present study to examine the outcome of children and adult patients with Ewing sarcoma and relevant prognostic factors... - Evaluation of myocardial blood flow reserve in patients with chronic congestive heart failure due to idiopathic dilated cardiomyopathyMenahem Canetti
Heart Failure Program, Division of Cardiology, University of Southern California Keck School of Medicine, Los Angeles, California, USA
Am J Cardiol 92:1246-9. 2003..An association between decreased response to adenosine and acetylcholine supports previous observations indicating that adenosine-induced vasodilation of coronary microcirculation is dependent on endothelial nitric oxide production... - Laparoscopic diagnosis and repair of asymptomatic bilateral inguinal herniasJason A Zell
Department of Surgery, College of Osteopathic Medicine, and Public Health Program, College of Allied Health, Nova Southeastern University, Ft. Lauderdale, FL, USA
Am J Surg 183:15-9. 2002..3 to 35.0) were found to be independent risk factors for BIH. CONCLUSIONS: Laparoscopy yields detection of BIH that would be missed by clinical examination alone. Furthermore, left-sided hernia and male sex were associated with BIH... - An unusual case of renal carcinomaJason A Zell
Pathology 38:370-1. 2006 - Plasma homocysteine levels and the left ventricular systolic function in coronary artery disease patientsSyed W Bokhari
University of Chicago Pritzker School of Medicine, Illinois 60637, USA
Coron Artery Dis 16:153-61. 2005..However, an association between hyperhomocysteinemia and the extent of coronary artery disease (CAD) remains controversial whereas its relationship with left ventricular systolic function has not been established... - Identification of HDM2 as a regulator of VEGF expression in cancer cellsMadhusudhanan Narasimhan
Department of Pharmaceutical Sciences, College of Pharmacy, Health Professions Division, Nova Southeastern University, 3200 S University Drive, Ft Lauderdale, FL 33328, USA
Life Sci 82:1231-41. 2008..Thus, our present study suggests that modulation of HDM2 expression could play an important role in tumor angiogenesis and the metastatic process via transcriptional regulation of VEGF...