Grazyna Zareba

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi Pregabalin: a new agent for the treatment of neuropathic pain
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, New York 14642, USA
    Drugs Today (Barc) 41:509-16. 2005
  2. pmc New treatment options in the management of fibromyalgia: role of pregabalin
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, NY, USA
    Neuropsychiatr Dis Treat 4:1193-201. 2008
  3. ncbi Validity of methyl mercury hair analysis: mercury monitoring in human scalp/nude mouse model
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Appl Toxicol 28:535-42. 2008
  4. ncbi Thimerosal distribution and metabolism in neonatal mice: comparison with methyl mercury
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Appl Toxicol 27:511-8. 2007
  5. ncbi A new combination vaccine for measles, mumps, rubella and varicella
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, New York 14642, USA
    Drugs Today (Barc) 42:321-9. 2006
  6. ncbi Torcetrapib and atorvastatin: a novel combination therapy for dyslipidemia
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, New York 14642, USA
    Drugs Today (Barc) 42:95-102. 2006
  7. ncbi Rotigotine: a novel dopamine agonist for the transdermal treatment of Parkinson's disease
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, New York 14642, USA
    Drugs Today (Barc) 42:21-8. 2006
  8. ncbi Zonisamide: review of its use in epilepsy therapy
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, 575 Elmwood Ave, Box EHSC, New York 14642, USA
    Drugs Today (Barc) 41:589-97. 2005
  9. ncbi Percutaneous absorption studies of octamethylcyclotetrasiloxane using the human skin/nude mouse model
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA
    Skin Pharmacol Appl Skin Physiol 15:184-94. 2002
  10. doi Phytotherapy for pain relief
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Drugs Today (Barc) 45:445-67. 2009

Detail Information

Publications24

  1. ncbi Pregabalin: a new agent for the treatment of neuropathic pain
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, New York 14642, USA
    Drugs Today (Barc) 41:509-16. 2005
    ..Furthermore, pregabalin has proven efficacy in adjunctive therapy of refractory partial seizures and in the treatment of acute pain, generalized anxiety disorder and social phobia...
  2. pmc New treatment options in the management of fibromyalgia: role of pregabalin
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, NY, USA
    Neuropsychiatr Dis Treat 4:1193-201. 2008
    ..Because of mild to moderate adverse effects it can be considered a well-tolerated therapy for FM...
  3. ncbi Validity of methyl mercury hair analysis: mercury monitoring in human scalp/nude mouse model
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Appl Toxicol 28:535-42. 2008
    ..The grafting of human scalp hair was used as a new application of this method to explore methyl mercury incorporation into human hair and to validate this model for mercury monitoring in hair...
  4. ncbi Thimerosal distribution and metabolism in neonatal mice: comparison with methyl mercury
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Appl Toxicol 27:511-8. 2007
    ..The data showing significant kinetic differences in tissue distribution and metabolism of mercury species challenge the assumption that ethyl mercury is toxicologically identical to methyl mercury...
  5. ncbi A new combination vaccine for measles, mumps, rubella and varicella
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, New York 14642, USA
    Drugs Today (Barc) 42:321-9. 2006
    ..The ProQuad combination vaccine facilitates implementation of varicella vaccination into routine childhood immunization schedules and will help to protect children against these four potentially serious diseases...
  6. ncbi Torcetrapib and atorvastatin: a novel combination therapy for dyslipidemia
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, New York 14642, USA
    Drugs Today (Barc) 42:95-102. 2006
    ....
  7. ncbi Rotigotine: a novel dopamine agonist for the transdermal treatment of Parkinson's disease
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, New York 14642, USA
    Drugs Today (Barc) 42:21-8. 2006
    ..Clinical studies on rotigotine, the first transdermally delivered dopamine agonist, are now in progress, and regulatory approval is expected in the near future...
  8. ncbi Zonisamide: review of its use in epilepsy therapy
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, 575 Elmwood Ave, Box EHSC, New York 14642, USA
    Drugs Today (Barc) 41:589-97. 2005
    ..It has a good pharmacokinetic profile and a low drug interaction potential. Zonisamide is considered as a drug that effectively reduces the frequency of partial seizures...
  9. ncbi Percutaneous absorption studies of octamethylcyclotetrasiloxane using the human skin/nude mouse model
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA
    Skin Pharmacol Appl Skin Physiol 15:184-94. 2002
    ..The fraction of the percutaneous dose of D(4) absorbed in this model was found to be consistent with results reported by others using different experimental approaches...
  10. doi Phytotherapy for pain relief
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Drugs Today (Barc) 45:445-67. 2009
    ....
  11. doi Idursulfase in Hunter syndrome treatment
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester, School of Medicine and Dentistry, Rochester, New York, USA
    Drugs Today (Barc) 43:759-67. 2007
    ..Clinical studies demonstrate that idursulfase may be the first successful symptomatic therapy that can benefit patients with MPS II by addressing the enzymatic defect...
  12. pmc Prenatal exposure to dental amalgam in the Seychelles Child Development Nutrition Study: associations with neurodevelopmental outcomes at 9 and 30 months
    GENE E WATSON
    Eastman Institute for Oral Health, and Department of Pharmacology and Physiology, University of Rochester, Rochester, NY 14642, USA
    Neurotoxicology 33:1511-7. 2012
    ..Maternal amalgams expose the developing fetus to mercury vapor. Mercury vapor can be toxic, but uncertainty remains whether prenatal amalgam exposure is associated with neurodevelopmental consequences in offspring...
  13. pmc Fish consumption and prenatal methylmercury exposure: cognitive and behavioral outcomes in the main cohort at 17 years from the Seychelles child development study
    Philip W Davidson
    Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 32:711-7. 2011
    ..For some endpoints we found performance improved with increasing prenatal exposure to MeHg. Follow up studies indicate this association is related to the beneficial nutrients present in fish...
  14. pmc Mercury levels in premature and low birth weight newborn infants after receipt of thimerosal-containing vaccines
    Michael E Pichichero
    University of Rochester, Rochester, NY, USA
    J Pediatr 155:495-9. 2009
    ....
  15. pmc Autism spectrum disorder phenotypes and prenatal exposure to methylmercury
    Edwin van Wijngaarden
    Department of Public Health Sciences, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Epidemiology 24:651-9. 2013
    ..We evaluated the association between prenatal methylmercury exposure and ASD phenotype in children and adolescents in the Republic of Seychelles, where fish consumption is high...
  16. pmc Prenatal exposure to dental amalgam: evidence from the Seychelles Child Development Study main cohort
    GENE E WATSON
    Eastman Institute for Oral Health, Department of Environmental Medicine, and Department of Pharmacology and Physiology, School of Medicine and Dentistry, University of Rochester, N Y, USA
    J Am Dent Assoc 142:1283-94. 2011
    ..Controversy surrounds whether fetal exposure to mercury vapor resulting from maternal dental amalgam restorations has neurodevelopmental consequences...
  17. ncbi Sex-specific alterations of cerebral cortical cell size in rats exposed prenatally to dioxin
    Rieko Hojo
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Appl Toxicol 26:25-34. 2006
    ..These findings demonstrate that prenatal exposure to TCDD alters the normal patterns of cortical cell asymmetry in a manner consistent with our previous data on thickness patterns...
  18. pmc Organic and inorganic mercury in neonatal rat brain after prenatal exposure to methylmercury and mercury vapor
    Hiromi Ishitobi
    Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642, USA
    Environ Health Perspect 118:242-8. 2010
    ..Most of our knowledge of the neurotoxicity of Hg is based on research devoted to studying only one form at a time, mostly MeHg...
  19. doi Neurodevelopmental outcomes at 5 years in children exposed prenatally to maternal dental amalgam: the Seychelles Child Development Nutrition Study
    GENE E WATSON
    Eastman Institute for Oral Health, University of Rochester, 601 Elmwood Avenue, Box 705, Rochester, NY 14642, USA Department of Environmental Medicine, University of Rochester, 601 Elmwood Avenue, Box EHSC, Rochester, NY 14642, USA Department of Pharmacology and Physiology, University of Rochester, 601 Elmwood Avenue, Box 705, Rochester, NY 14642, USA Electronic address
    Neurotoxicol Teratol 39:57-62. 2013
    ..Our findings do not provide evidence to support a relationship between prenatal exposure to Hg⁰ from maternal dental amalgam and neurodevelopmental outcomes in children at 5 years of age...
  20. ncbi Sexually dimorphic alterations of brain cortical dominance in rats prenatally exposed to TCDD
    Grazyna Zareba
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Appl Toxicol 22:129-37. 2002
    ..These data demonstrate that prenatal exposure to TCDD reduces cortical thickness and alters the normal pattern of cortical asymmetry, a finding consistent with the sexually dimorphic behavioral effects induced by this agent...
  21. doi Mercury levels in newborns and infants after receipt of thimerosal-containing vaccines
    Michael E Pichichero
    Department of Microbiology Immunology, Pediatrics, and Medicine, University of Rochester, Rochester, New York 14642, USA
    Pediatrics 121:e208-14. 2008
    ..We conducted a pharmacokinetic study to assess blood levels and elimination of ethyl mercury after vaccination of infants with thimerosal-containing vaccines...
  22. doi Sex-dependent and non-monotonic enhancement and unmasking of methylmercury neurotoxicity by prenatal stress
    Hiromi I Weston
    Department of Environmental Health Sciences, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States
    Neurotoxicology 41:123-40. 2014
    ..Thus, assessment of risks associated with MeHg may be underestimated in the absence of other extant risk factors with which it may share common substrates and effects. ..
  23. pmc Fish consumption, mercury exposure, and their associations with scholastic achievement in the Seychelles Child Development Study
    Philip W Davidson
    University of Rochester, School of Medicine and Dentistry, Department of Pediatrics, Rochester, NY 14642, USA
    Neurotoxicology 31:439-47. 2010
    ..The adverse association of educational measures with postnatal exposure in males is intriguing, but will need to be confirmed by further studies examining factors that influence scholastic achievement...
  24. pmc Sexually dimorphic behavioral responses to prenatal dioxin exposure
    Rieko Hojo
    Department of Environmental Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Environ Health Perspect 110:247-54. 2002
    ..02 ng/kg. The corresponding ED(01) was 0.30 ng/kg with a 95% lower bound of 0.20 ng/kg. These values fall close to, but below, current estimates of human body burdens of 13 ng/kg, based on TCDD toxic equivalents...