Michael V Zaragoza

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Mitochondrial cardiomyopathies: how to identify candidate pathogenic mutations by mitochondrial DNA sequencing, MITOMASTER and phylogeny
    Michael V Zaragoza
    Center for Mitochondrial and Molecular Medicine and Genetics, University of California, Irvine, CA 92697, USA
    Eur J Hum Genet 19:200-7. 2011
  2. ncbi request reprint Noncompaction of the left ventricle: primary cardiomyopathy with an elusive genetic etiology
    Michael V Zaragoza
    Center for Molecular and Mitochondrial Medicine and Genetics and the Department of Pediatrics, Division of Genetics and Metabolism, University of California, Irvine, California 92697 3940, USA
    Curr Opin Pediatr 19:619-27. 2007
  3. pmc Mitochondrial DNA variant discovery and evaluation in human Cardiomyopathies through next-generation sequencing
    Michael V Zaragoza
    Genetics and Metabolism Division, Pediatrics Department and Center for Mitochondrial and Molecular Medicine and Genetics, University of California Irvine, Irvine, California, United States of America
    PLoS ONE 5:e12295. 2010
  4. pmc Intrafamilial variability for novel TAZ gene mutation: Barth syndrome with dilated cardiomyopathy and heart failure in an infant and left ventricular noncompaction in his great-uncle
    Diti Ronvelia
    UC Irvine Cardiogenomics Program, University of California, Irvine, School of Medicine, Irvine, CA 92697 3940, USA
    Mol Genet Metab 107:428-32. 2012
  5. doi request reprint Adenine nucleotide translocase 1 deficiency results in dilated cardiomyopathy with defects in myocardial mechanics, histopathological alterations, and activation of apoptosis
    Nupoor Narula
    Center for Mitochondrial and Molecular Medicine and Genetics MAMMAG, University of California, Irvine, California, USA
    JACC Cardiovasc Imaging 4:1-10. 2011
  6. ncbi request reprint A homozygous nonsense mutation in SOX9 in the dominant disorder campomelic dysplasia: a case of mitotic gene conversion
    Ramona Pop
    Institute of Human Genetics and Anthropology, University of Freiburg, Germany
    Hum Genet 117:43-53. 2005

Research Grants

Collaborators

Detail Information

Publications6

  1. pmc Mitochondrial cardiomyopathies: how to identify candidate pathogenic mutations by mitochondrial DNA sequencing, MITOMASTER and phylogeny
    Michael V Zaragoza
    Center for Mitochondrial and Molecular Medicine and Genetics, University of California, Irvine, CA 92697, USA
    Eur J Hum Genet 19:200-7. 2011
    ....
  2. ncbi request reprint Noncompaction of the left ventricle: primary cardiomyopathy with an elusive genetic etiology
    Michael V Zaragoza
    Center for Molecular and Mitochondrial Medicine and Genetics and the Department of Pediatrics, Division of Genetics and Metabolism, University of California, Irvine, California 92697 3940, USA
    Curr Opin Pediatr 19:619-27. 2007
    ..Understanding the genetics may depend on clarifying the distinctive diagnostic features and investigating the contribution of all known cardiomyopathy-causing genes with overlapping morphology...
  3. pmc Mitochondrial DNA variant discovery and evaluation in human Cardiomyopathies through next-generation sequencing
    Michael V Zaragoza
    Genetics and Metabolism Division, Pediatrics Department and Center for Mitochondrial and Molecular Medicine and Genetics, University of California Irvine, Irvine, California, United States of America
    PLoS ONE 5:e12295. 2010
    ..We hope that this will assist in the identification of mtDNA mutations and key genetic determinants for cardiomyopathy and mitochondrial disease...
  4. pmc Intrafamilial variability for novel TAZ gene mutation: Barth syndrome with dilated cardiomyopathy and heart failure in an infant and left ventricular noncompaction in his great-uncle
    Diti Ronvelia
    UC Irvine Cardiogenomics Program, University of California, Irvine, School of Medicine, Irvine, CA 92697 3940, USA
    Mol Genet Metab 107:428-32. 2012
    ..TAZ mutations also contribute to left ventricular noncompaction (LVNC), a cardiomyopathy characterized by loose, trabeculated myocardium...
  5. doi request reprint Adenine nucleotide translocase 1 deficiency results in dilated cardiomyopathy with defects in myocardial mechanics, histopathological alterations, and activation of apoptosis
    Nupoor Narula
    Center for Mitochondrial and Molecular Medicine and Genetics MAMMAG, University of California, Irvine, California, USA
    JACC Cardiovasc Imaging 4:1-10. 2011
    ....
  6. ncbi request reprint A homozygous nonsense mutation in SOX9 in the dominant disorder campomelic dysplasia: a case of mitotic gene conversion
    Ramona Pop
    Institute of Human Genetics and Anthropology, University of Freiburg, Germany
    Hum Genet 117:43-53. 2005
    ..This is, to our knowledge, the first report of mitotic gene conversion of a wild-type allele by a de novo mutant allele in humans...

Research Grants2

  1. Mitochondrial Dysfunction & Noncompaction Cardiomyopathy
    MICHAEL ZARAGOZA; Fiscal Year: 2007
    ..Through the combination of supervised research, scientific exchange and selected coursework, the applicant will obtain the training necessary for a successful transition to an independent investigator. (End of Abstract) ..