Research Topics
| James ZacnySummaryAffiliation: University of Chicago Country: USA Publications
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Detail Information
Publications
Preoperative dental anxiety and mood changes during nitrous oxide inhalationJames P Zacny
Department of Anesthesia and Critical Care, The University of Chicago, Ill 60637, USA
J Am Dent Assoc 133:82-8. 2002..The purpose of this study was to characterize mood changes during nitrous oxide inhalation in patients with different levels of preoperative dental anxiety...
Characterizing the subjective, psychomotor, and physiological effects of oral propoxyphene in non-drug-abusing volunteersJames P Zacny
Department of Anesthesia and Critical Care, The Pritzker School of Medicine, The University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA
Drug Alcohol Depend 73:133-40. 2004..The drug also has potential for abuse and it was of interest in the present study to determine if the drug had any abuse liability-related subjective effects in this population...
Characterizing the subjective, psychomotor, and physiological effects of oral oxycodone in non-drug-abusing volunteersJames P Zacny
Department of Anesthesia and Critical Care MC 4028, The Pritzker School of Medicine, University of Chicago, 5841 S Maryland Avenue, Chicago, IL 60637, USA
Psychopharmacology (Berl) 170:242-54. 2003..The subjective, psychomotor, and physiological effects of a widely prescribed and abused prescription opioid, oxycodone, have not been studied in a population of non-drug-abusing people...
College on Problems of Drug Dependence taskforce on prescription opioid non-medical use and abuse: position statementJames Zacny
Department of Anesthesia and Critical Care, University of Chicago, Box MC4028, 5841 S Maryland Avenue, Chicago, IL 60637, USA
Drug Alcohol Depend 69:215-32. 2003....
Characterizing the subjective, psychomotor, and physiological effects of a hydrocodone combination product (Hycodan) in non-drug-abusing volunteersJames P Zacny
Department of Anesthesia and Critical Care MC4028, Pritzker School of Medicine, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA
Psychopharmacology (Berl) 165:146-56. 2003....
Choice of sevoflurane and its subjective and psychomotor effects in light and moderate drinkersJames P Zacny
Department of Anesthesia and Critical Care, The University of Chicago, Chicago, IL 60637, USA
Drug Alcohol Depend 94:101-8. 2008..We sought to determine if choice for subanesthetic doses of sevoflurane, and its subjective and psychomotor effects, would differ as a function of alcohol-drinking status in healthy volunteers...
Nonmedical use of prescription opioids: motive and ubiquity issuesJames P Zacny
Department of Anesthesia and Critical Care, The University of Chicago, Chicago, Illinois 60637, USA
J Pain 9:473-86. 2008..Such information would allow for a better understanding of the problem. We invite discussion and commentaries regarding the issues we raise to more effectively address this public health issue...
Within-subject comparison of the psychopharmacological profiles of oral oxycodone and oral morphine in non-drug-abusing volunteersJames P Zacny
Department of Anesthesia and Critical Care MC4028, The University of Chicago, 5841 S Maryland Avenue, Chicago, IL 60637, USA
Psychopharmacology (Berl) 196:105-16. 2008..Little attention has been paid to assessing the relative psychopharmacological profile (including abuse liability-related effects) of specific prescription opioids...
Within-subject comparison of the subjective and psychomotor effects of a gaseous anesthetic and two volatile anesthetics in healthy volunteersNancy J Beckman
Department of Anesthesia and Critical Care, The University of Chicago, 5841 S. Maryland Avenue, MC 4028, Chicago, IL 60637, USA
Drug Alcohol Depend 81:89-95. 2006..These results are consistent with the drugs' putative receptor mechanisms of action and confirm Balster's classification of the volatile anesthetics into a class distinct from N2O...
Profiling the subjective, psychomotor, and physiological effects of tramadol in recreational drug usersJames P Zacny
Department of Anesthesia and Critical Care, University of Chicago, 5841 S Maryland Avenue, Chicago, IL 60637, USA
Drug Alcohol Depend 80:273-8. 2005....
Profiling the subjective, psychomotor, and physiological effects of a hydrocodone/acetaminophen product in recreational drug usersJames P Zacny
Department of Anesthesia and Critical Care, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA
Drug Alcohol Depend 78:243-52. 2005..It was of particular interest to determine if HYD/ACET had abuse liability-related subjective effects in a population of recreational drug users...
Reinforcing and subjective effects of the volatile anesthetic, sevofluraneDiana J Walker
Department of Anesthesia and Critical Care, University of Chicago, 5841 S Maryland Ave, MC 4028, Chicago, IL 60637, USA
Drug Alcohol Depend 76:191-201. 2004..This study shows that sevoflurane can function as a reinforcer and produce abuse liability-related subjective effects in some healthy volunteers...
The effects of a cold-water stimulus on butorphanol effects in males and femalesJames P Zacny
Department of Anesthesia and Critical Care, The University of Chicago, MC 4028, 5841 S Maryland Avenue, Chicago, IL 60637, USA
Pharmacol Biochem Behav 78:653-9. 2004..The differences in pain ratings and degree of analgesia between the sexes are discussed as a possible mechanism for the sex differences in modulatory effects...
Assessing subjective and psychomotor effects of the herbal medication valerian in healthy volunteersSandra Gutierrez
Department of Anesthesia and Critical Care, The University of Chicago, MC4028, 5841 South Maryland Avenue, Chicago, IL 60637, USA
Pharmacol Biochem Behav 78:57-64. 2004..The data suggest that acute administration of valerian does not have mood-altering or psychomotor/cognitive effects in young healthy volunteers...
Bitonic dose-response functions for reinforcing and self-reported effects of nitrous oxide in humansDiana J Walker
Department of Anesthesia and Critical Care, The University of Chicago, 5841 South Maryland Avenue, MC 4028, Chicago, IL 60637, USA
Pharmacol Biochem Behav 74:851-7. 2003..Bitonic dose-response functions for some subjects extend the generality of the phenomenon of bitonicity of drug effects to N(2)O effects in humans...
Analysis of the reinforcing and subjective effects of different doses of nitrous oxide using a free-choice procedureDiana J Walker
Department of Anesthesia and Critical Care, The University of Chicago, 5841 S Maryland Ave, MC 4028, Chicago, IL 60637, USA
Drug Alcohol Depend 66:93-103. 2002..Reinforcing effects were more correlated with subjective effects assessed after the session than with subjective effects obtained while subjects were under the influence of the drug...
Subjective, psychomotor, and physiological effects profile of hydrocodone/acetaminophen and oxycodone/acetaminophen combination productsJames P Zacny
Department of Anesthesia and Critical Care, University of Chicago, Chicago, Illinois 60637, USA
Pain Med 9:433-43. 2008..To compare within the same individuals two typically prescribed doses of hydrocodone/acetaminophen and oxycodone/acetaminophen products for their subjective, psychomotor, and physiological effects in healthy volunteers...
Differential effects of morphine and codeine on pupil size: dosing issuesJames P Zacny
Anesth Analg 100:598; author reply 598. 2005
Chronic pain and driving: proceed with cautionJames P Zacny
Pain 122:6-7. 2006
