Michele A Zacks

Summary

Affiliation: University of Texas Medical Branch
Country: USA

Publications

  1. ncbi request reprint Impairment of cell division of Trypanosoma cruzi epimastigotes
    Michele A Zacks
    Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555 0609, USA
    Mem Inst Oswaldo Cruz 102:111-5. 2007
  2. pmc Alpha-beta T cells provide protection against lethal encephalitis in the murine model of VEEV infection
    Slobodan Paessler
    Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555 0609, USA
    Virology 367:307-23. 2007
  3. pmc Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers
    Slobodan Paessler
    Department of Pathology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 1019, USA
    Virology 376:357-70. 2008
  4. pmc CD4+ T cells provide protection against acute lethal encephalitis caused by Venezuelan equine encephalitis virus
    Nadezhda E Yun
    Department of Pathology, Galveston National Laboratory and Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX 77555 0609, United States
    Vaccine 27:4064-73. 2009
  5. ncbi request reprint Recombinant alphaviruses are safe and useful serological diagnostic tools
    Haolin Ni
    Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555, USA
    Am J Trop Med Hyg 76:774-81. 2007
  6. pmc Pathogenesis of XJ and Romero strains of Junin virus in two strains of guinea pigs
    Nadezhda E Yun
    Center for Biodefense and Emerging Infectious Diseases, Institute for Human Infections and Immunity, Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 1019, USA
    Am J Trop Med Hyg 79:275-82. 2008
  7. pmc Encephalitic alphaviruses
    Michele A Zacks
    Galveston National Laboratory, Department of Pathology, University of Texas Medical Branch, G 170 Keiller Building, Galveston, TX 77555 0609, United States
    Vet Microbiol 140:281-6. 2010
  8. ncbi request reprint An overview of chagasic cardiomyopathy: pathogenic importance of oxidative stress
    Michele A Zacks
    Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA
    An Acad Bras Cienc 77:695-715. 2005
  9. pmc Injectable peramivir mitigates disease and promotes survival in ferrets and mice infected with the highly virulent influenza virus, A/Vietnam/1203/04 (H5N1)
    Nadezhda E Yun
    Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA
    Virology 374:198-209. 2008

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Impairment of cell division of Trypanosoma cruzi epimastigotes
    Michele A Zacks
    Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555 0609, USA
    Mem Inst Oswaldo Cruz 102:111-5. 2007
    ..This report describes a developmentally-defective phenotype that resulted from integration of a drug marker adjacent to the GAPDH gene in T. cruzi...
  2. pmc Alpha-beta T cells provide protection against lethal encephalitis in the murine model of VEEV infection
    Slobodan Paessler
    Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555 0609, USA
    Virology 367:307-23. 2007
    ..Prolonged replication of encephalitic VEEV in the brain of pre-immunized mice is not lethal and adoptive transfer experiments indicate that CD3(+) T cells are required for protection...
  3. pmc Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers
    Slobodan Paessler
    Department of Pathology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 1019, USA
    Virology 376:357-70. 2008
    ..Levels of virus in tissue samples correlated with animal survival. Uninfected mice suffered no apparent ill-effects from PPMO treatment. Thus, PPMO appear promising as candidates for therapeutic development against alphaviruses...
  4. pmc CD4+ T cells provide protection against acute lethal encephalitis caused by Venezuelan equine encephalitis virus
    Nadezhda E Yun
    Department of Pathology, Galveston National Laboratory and Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX 77555 0609, United States
    Vaccine 27:4064-73. 2009
    ..On the contrary, the adoptive transfer of primed CD4(+) T cells was necessary to prevent lethal encephalitis in mice lacking alphabeta T cell receptor...
  5. ncbi request reprint Recombinant alphaviruses are safe and useful serological diagnostic tools
    Haolin Ni
    Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555, USA
    Am J Trop Med Hyg 76:774-81. 2007
    ..Chimeric viruses were produced efficiently in cell culture and were as effective as the parental virus for identifying infection of humans, horses, and rodents in these serological assays...
  6. pmc Pathogenesis of XJ and Romero strains of Junin virus in two strains of guinea pigs
    Nadezhda E Yun
    Center for Biodefense and Emerging Infectious Diseases, Institute for Human Infections and Immunity, Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 1019, USA
    Am J Trop Med Hyg 79:275-82. 2008
    ..Thus, both guinea pig strains are useful animal models for lethal Junin virus (Romero strain) infection and potentially can be used for preclinical trials in vaccine or antiviral drug development...
  7. pmc Encephalitic alphaviruses
    Michele A Zacks
    Galveston National Laboratory, Department of Pathology, University of Texas Medical Branch, G 170 Keiller Building, Galveston, TX 77555 0609, United States
    Vet Microbiol 140:281-6. 2010
    ..In contrast, transmission of VEEV occurs predominantly in Central and South America. As with their geographical distribution, equine encephalitis viruses differ in their main mosquito vector species and their zoonotic potential...
  8. ncbi request reprint An overview of chagasic cardiomyopathy: pathogenic importance of oxidative stress
    Michele A Zacks
    Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA
    An Acad Bras Cienc 77:695-715. 2005
    ..We discuss the literature reporting the consequences of sustained oxidative stress in CCM pathogenesis...
  9. pmc Injectable peramivir mitigates disease and promotes survival in ferrets and mice infected with the highly virulent influenza virus, A/Vietnam/1203/04 (H5N1)
    Nadezhda E Yun
    Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA
    Virology 374:198-209. 2008
    ..A single intramuscular peramivir injection protected mice against severe disease outcomes following infection with highly pathogenic avian influenza and multi-dose treatment was efficacious in ferrets...