Steven A Yukl
Affiliation: University of California
- Latently-infected CD4+ T cells are enriched for HIV-1 Tat variants with impaired transactivation activitySteven Yukl
University of California, San Francisco UCSF and San Francisco VA Medical Center SFVAMC, 4150 Clement Street, 111W3, San Francisco, CA 94121, USA
Virology 387:98-108. 2009..These findings suggest that impaired activity in the Tat-TAR axis may contribute to the establishment of latent infection in CD4+ T cells...
- Effect of raltegravir-containing intensification on HIV burden and T-cell activation in multiple gut sites of HIV-positive adults on suppressive antiretroviral therapySteven A Yukl
San Francisco VA Medical Center SFVAMC and University of California, San Francisco UCSF, San Francisco, California, USA
AIDS 24:2451-60. 2010..To determine whether raltegravir-containing antiretroviral therapy (ART) intensification reduces HIV levels in the gut...
- Differences in HIV burden and immune activation within the gut of HIV-positive patients receiving suppressive antiretroviral therapySteven A Yukl
San Francisco Veterans Affairs Medical Center, San Francisco, California, USA
J Infect Dis 202:1553-61. 2010..The gut is a major reservoir for human immunodeficiency virus (HIV) in patients receiving antiretroviral therapy (ART). We hypothesized that distinct immune environments within the gut may support varying levels of HIV...
- Modification of the Abbott RealTime assay for detection of HIV-1 plasma RNA viral loads less than one copy per milliliterSteven A Yukl
San Francisco VA Medical Center, San Francisco, CA 94121, USA
J Virol Methods 175:261-5. 2011..77 copy/ml; 95% CI 0.86-4.68 copy/ml). The measured viral load correlated inversely (r = -0.78; p = 0.028) with the total duration of viral suppression (viral load<40 copies/ml)...