Zhen Yuan

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi High-resolution x-ray guided three-dimensional diffuse optical tomography of joint tissues in hand osteoarthritis: morphological and functional assessments
    Zhen Yuan
    Department of Biomedical Engineering, University of Florida, Gainesville, 32611, USA
    Med Phys 37:4343-54. 2010
  2. ncbi Finite-element-based photoacoustic tomography: phantom and chicken bone experiments
    Zhen Yuan
    Department of Biomedical Engineering, University of Florida, Gainesville 32611 6131, USA
    Appl Opt 45:3177-83. 2006
  3. ncbi Imaging of small nanoparticle-containing objects by finite-element-based photoacoustic tomography
    Zhen Yuan
    Department of Biomedical Engineering, University of Florida, Gainesville 32611, USA
    Opt Lett 30:3054-6. 2005
  4. ncbi Comparison of diffusion approximation and higher order diffusion equations for optical tomography of osteoarthritis
    Zhen Yuan
    University of Florida, Department of Biomedical Engineering, 130 BME Building, P O Box 116131, Gainesville, Florida 32611 6131, USA
    J Biomed Opt 14:054013. 2009
  5. ncbi A higher order diffusion model for three-dimensional photon migration and image reconstruction in optical tomography
    Zhen Yuan
    Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA
    Phys Med Biol 54:65-88. 2009
  6. ncbi Tomographic x-ray-guided three-dimensional diffuse optical tomography of osteoarthritis in the finger joints
    Zhen Yuan
    University of Florida, Department of Biomedical Engineering, Gainesville, Florida 32611 6131, USA
    J Biomed Opt 13:044006. 2008
  7. ncbi Three-dimensional diffuse optical tomography of osteoarthritis: initial results in the finger joints
    Zhen Yuan
    University of Florida, Department of Biomedical Engineering, Gainesville, Florida 32611 6131, USA
    J Biomed Opt 12:034001. 2007
  8. ncbi Spatially varying optical and acoustic property reconstruction using finite-element-based photoacoustic tomography
    Huabei Jiang
    Department of Biomedical Engineering, University of Florida, Gainesville 32611, USA
    J Opt Soc Am A Opt Image Sci Vis 23:878-88. 2006
  9. ncbi Three-dimensional finite-element-based photoacoustic tomography: reconstruction algorithm and simulations
    Zhen Yuan
    Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611 6131, USA
    Med Phys 34:538-46. 2007
  10. ncbi Quantitative bioluminescence tomography guided by diffuse optical tomography
    Qizhi Zhang
    J Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA
    Opt Express 16:1481-6. 2008

Collaborators

Detail Information

Publications17

  1. ncbi High-resolution x-ray guided three-dimensional diffuse optical tomography of joint tissues in hand osteoarthritis: morphological and functional assessments
    Zhen Yuan
    Department of Biomedical Engineering, University of Florida, Gainesville, 32611, USA
    Med Phys 37:4343-54. 2010
    ..The aim of this study was to investigate the potential use of multimodality functional imaging techniques to identify the quantitative optical findings that can be used to distinguish between osteoarthritic and normal finger joints...
  2. ncbi Finite-element-based photoacoustic tomography: phantom and chicken bone experiments
    Zhen Yuan
    Department of Biomedical Engineering, University of Florida, Gainesville 32611 6131, USA
    Appl Opt 45:3177-83. 2006
    ..The results obtained show that millimeter-sized phantom objects and chicken bones and/or joints can be clearly detected using our finite-element-based photoacoustic tomography method...
  3. ncbi Imaging of small nanoparticle-containing objects by finite-element-based photoacoustic tomography
    Zhen Yuan
    Department of Biomedical Engineering, University of Florida, Gainesville 32611, USA
    Opt Lett 30:3054-6. 2005
    ..The results obtained show that millimeter-size nanoparticle-containing objects can be clearly detected in terms of position, size, and relative optical properties...
  4. ncbi Comparison of diffusion approximation and higher order diffusion equations for optical tomography of osteoarthritis
    Zhen Yuan
    University of Florida, Department of Biomedical Engineering, 130 BME Building, P O Box 116131, Gainesville, Florida 32611 6131, USA
    J Biomed Opt 14:054013. 2009
    ..The results show that the reconstruction error between these two models is about 15 and 4%, respectively, for stand-alone and image-guided frameworks...
  5. ncbi A higher order diffusion model for three-dimensional photon migration and image reconstruction in optical tomography
    Zhen Yuan
    Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA
    Phys Med Biol 54:65-88. 2009
    ..We conclude that the developed higher order diffusion model is able to accurately describe light propagation in biological tissues and to offer improved image reconstruction...
  6. ncbi Tomographic x-ray-guided three-dimensional diffuse optical tomography of osteoarthritis in the finger joints
    Zhen Yuan
    University of Florida, Department of Biomedical Engineering, Gainesville, Florida 32611 6131, USA
    J Biomed Opt 13:044006. 2008
    ..In particular, the improved quantitative capability of imaging absorption and scattering coefficients of the joint tissues allows for more accurate diagnosis of osteoarthritis over x-ray radiography or DOT alone...
  7. ncbi Three-dimensional diffuse optical tomography of osteoarthritis: initial results in the finger joints
    Zhen Yuan
    University of Florida, Department of Biomedical Engineering, Gainesville, Florida 32611 6131, USA
    J Biomed Opt 12:034001. 2007
    ..The results of this pilot study show potential for quantitative imaging and diagnosis of early OA by DOT...
  8. ncbi Spatially varying optical and acoustic property reconstruction using finite-element-based photoacoustic tomography
    Huabei Jiang
    Department of Biomedical Engineering, University of Florida, Gainesville 32611, USA
    J Opt Soc Am A Opt Image Sci Vis 23:878-88. 2006
    ..The effect of acoustic heterogeneity on conventional pure optical absorption reconstruction is also studied...
  9. ncbi Three-dimensional finite-element-based photoacoustic tomography: reconstruction algorithm and simulations
    Zhen Yuan
    Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611 6131, USA
    Med Phys 34:538-46. 2007
    ..The results show that the algorithm is able to reconstruct photoacoustic images quantitatively in terms of the location, size, optical and acoustic properties of the target, and background media for various examples examined...
  10. ncbi Quantitative bioluminescence tomography guided by diffuse optical tomography
    Qizhi Zhang
    J Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA
    Opt Express 16:1481-6. 2008
    ....
  11. ncbi Image reconstruction scheme that combines modified Newton method and efficient initial guess estimation for optical tomography of finger joints
    Zhen Yuan
    Department of Biomedical Engineering, University of Florida, FL 32611 6131, USA
    Appl Opt 46:2757-68. 2007
    ..The recovered results suggest that the improved approach is able to provide quantitatively better images than our previous algorithm for optical tomography reconstruction...
  12. ncbi Photoacoustic tomography for imaging nanoparticles
    Zhen Yuan
    Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA
    Methods Mol Biol 624:309-24. 2010
    ..In this chapter, we described in detail photoacoustic reconstruction methods and imaging systems. We also review the recent advances in nanoparticles and their in vivo applications in the field of photoacoustic imaging...
  13. ncbi Quantitative photoacoustic tomography
    Zhen Yuan
    Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA
    Philos Trans A Math Phys Eng Sci 367:3043-54. 2009
    ..Simulation and in vivo experiments are used to demonstrate the effectiveness of the reconstruction algorithms presented...
  14. ncbi Non-invasive imaging of epileptic seizures in vivo using photoacoustic tomography
    Qizhi Zhang
    The J Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA
    Phys Med Biol 53:1921-31. 2008
    ....
  15. ncbi Reconstruction of optical absorption coefficient maps of heterogeneous media by photoacoustic tomography coupled with diffusion equation based regularized Newton method
    Zhen Yuan
    Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA
    Opt Express 15:18076-81. 2007
    ..The reconstruction results show that the optical absorption coefficient images obtained are quantitative in terms of the shape, size, location and optical property values of the heterogeneities examined...
  16. ncbi Simultaneous recovery of tissue physiological and acoustic properties and the criteria for wavelength selection in multispectral photoacoustic tomography
    Zhen Yuan
    Department of Biomedical Engineering, University of Florida, Gainesville, Florida 32611 6131, USA
    Opt Lett 34:1714-6. 2009
    ..We found that the image quality and the separation between acoustic velocity and different chromophore concentrations strongly depend on the measurement wavelengths of incident laser source...
  17. ncbi A calibration-free, one-step method for quantitative photoacoustic tomography
    Zhen Yuan
    Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA
    Med Phys 39:6895-9. 2012
    ..The purpose of this study is to develop a new algorithm for the reconstruction of optical absorption coefficient that does not depend on these initial parameters...