Fenghua Yuan

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. doi Eukaryotic DNA mismatch repair in vitro
    Fenghua Yuan
    Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL, USA
    Methods Mol Biol 920:149-62. 2012
  2. pmc Fanconi anemia complementation group A (FANCA) protein has intrinsic affinity for nucleic acids with preference for single-stranded forms
    Fenghua Yuan
    Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    J Biol Chem 287:4800-7. 2012
  3. doi Measuring strand discontinuity-directed mismatch repair in yeast Saccharomyces cerevisiae by cell-free nuclear extracts
    Fenghua Yuan
    Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Methods 48:14-8. 2009
  4. pmc Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein
    Anaid Benitez
    Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA, Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA 15213, USA and Department of Epidemiology and Public Health, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Nucleic Acids Res 42:1671-83. 2014
  5. ncbi Assembling an orchestra: Fanconi anemia pathway of DNA repair
    Fenghua Yuan
    Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Front Biosci (Landmark Ed) 15:1131-49. 2010
  6. pmc Human Fanconi anemia complementation group a protein stimulates the 5' flap endonuclease activity of FEN1
    Liangyue Qian
    Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, Florida, United States of America
    PLoS ONE 8:e82666. 2013
  7. doi Does a helicase activity help mismatch repair in eukaryotes?
    Limin Song
    Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    IUBMB Life 62:548-53. 2010
  8. pmc FANCI protein binds to DNA and interacts with FANCD2 to recognize branched structures
    Fenghua Yuan
    Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    J Biol Chem 284:24443-52. 2009

Collaborators

  • Yanbin Zhang
  • Chaitanya Jain
  • Liya Gu
  • Liangyue Qian
  • Anaid Benitez
  • Limin Song
  • Li Lan
  • Richard Myers
  • Satoshi Nakajima
  • Jennifer J Hu
  • Leizhen Wei
  • Suyog Padgaonkar
  • Paola Rodriguez-Tello

Detail Information

Publications8

  1. doi Eukaryotic DNA mismatch repair in vitro
    Fenghua Yuan
    Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL, USA
    Methods Mol Biol 920:149-62. 2012
    ..We validated the yeast cell-free system by the mismatch repair deficient strain (Δmsh2) and the complementation assay with purified yeast MutSα...
  2. pmc Fanconi anemia complementation group A (FANCA) protein has intrinsic affinity for nucleic acids with preference for single-stranded forms
    Fenghua Yuan
    Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    J Biol Chem 287:4800-7. 2012
    ....
  3. doi Measuring strand discontinuity-directed mismatch repair in yeast Saccharomyces cerevisiae by cell-free nuclear extracts
    Fenghua Yuan
    Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Methods 48:14-8. 2009
    ..The validity of the cell-free system was confirmed by the mismatch repair deficient yeast strain (Deltamsh2) and the complementation assay with purified yeast MSH2-MSH6...
  4. pmc Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein
    Anaid Benitez
    Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA, Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA 15213, USA and Department of Epidemiology and Public Health, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Nucleic Acids Res 42:1671-83. 2014
    ..This report clarifies the incision specificity of MUS81-EME1 on ICL damage and establishes that FANCA regulates the incision activity of MUS81-EME1 in a damage-dependent manner. ..
  5. ncbi Assembling an orchestra: Fanconi anemia pathway of DNA repair
    Fenghua Yuan
    Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Front Biosci (Landmark Ed) 15:1131-49. 2010
    ..Therefore, future biochemical studies are warranted to understand the biological functions of FA proteins and their implications in human diseases...
  6. pmc Human Fanconi anemia complementation group a protein stimulates the 5' flap endonuclease activity of FEN1
    Liangyue Qian
    Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, Florida, United States of America
    PLoS ONE 8:e82666. 2013
    ....
  7. doi Does a helicase activity help mismatch repair in eukaryotes?
    Limin Song
    Department of Biochemistry and Molecular Biology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    IUBMB Life 62:548-53. 2010
    ..This short review presents an overview of the interactions between eukaryotic DNA helicases and MMR factors, and suggests a possible mechanism for how DNA helicases may be involved in repair of DNA mismatches...
  8. pmc FANCI protein binds to DNA and interacts with FANCD2 to recognize branched structures
    Fenghua Yuan
    Department of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    J Biol Chem 284:24443-52. 2009
    ..Our data suggest that the FANCI-FANCD2 complex may participate in repair of damaged replication forks through its preferential recognition of branched structures...