Victor L Yu

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint Distribution of Legionella species and serogroups isolated by culture in patients with sporadic community-acquired legionellosis: an international collaborative survey
    Victor L Yu
    Veterans Affairs Medical Center, Infectious Disease Section, Pittsburgh, Pennsylvania 15240, USA
    J Infect Dis 186:127-8. 2002
  2. ncbi request reprint An international prospective study of pneumococcal bacteremia: correlation with in vitro resistance, antibiotics administered, and clinical outcome
    Victor L Yu
    Division of Infectious Disease, University of Pittsburgh, PA, USA
    Clin Infect Dis 37:230-7. 2003
  3. ncbi request reprint Staphylococcus aureus bacteremia: recurrence and the impact of antibiotic treatment in a prospective multicenter study
    Feng Yee Chang
    VA Medical Center, Infectious Disease Section, University Drive C, Pittsburgh, PA 15240, USA
    Medicine (Baltimore) 82:333-9. 2003
  4. ncbi request reprint Antibiotic therapy for Klebsiella pneumoniae bacteremia: implications of production of extended-spectrum beta-lactamases
    David L Paterson
    Infectious Disease Section, VA Medical Center, Pittsburgh, Pennsylvania 15240, USA
    Clin Infect Dis 39:31-7. 2004
  5. pmc Virulence characteristics of Klebsiella and clinical manifestations of K. pneumoniae bloodstream infections
    Victor L Yu
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Emerg Infect Dis 13:986-93. 2007
  6. ncbi request reprint Role of environmental surveillance in determining the risk of hospital-acquired legionellosis: a national surveillance study with clinical correlations
    Janet E Stout
    VA Pittsburgh Healthcare System, Pittsburgh, PA, USA
    Infect Control Hosp Epidemiol 28:818-24. 2007
  7. ncbi request reprint Effect of pipe corrosion scales on chlorine dioxide consumption in drinking water distribution systems
    Zhe Zhang
    Department of Civil and Environmental Engineering, School of Engineering, University of Pittsburgh, 943 Benedum Hall, Pittsburgh, PA 15261, USA
    Water Res 42:129-36. 2008
  8. ncbi request reprint Isolation of Staphylococcus aureus from the urinary tract: association of isolation with symptomatic urinary tract infection and subsequent staphylococcal bacteremia
    Robert R Muder
    Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA
    Clin Infect Dis 42:46-50. 2006
  9. doi request reprint Computer keyboard covers impregnated with a novel antimicrobial polymer significantly reduce microbial contamination
    Natalie N D'Antonio
    Special Pathogens Laboratory, Pittsburgh, PA, USA
    Am J Infect Control 41:337-9. 2013
  10. ncbi request reprint Comparative activity of quinolones, macrolides and ketolides against Legionella species using in vitro broth dilution and intracellular susceptibility testing
    Janet E Stout
    VA Pittsburgh Healthcare System, VA Medical Center, Infectious Disease Section, University Drive C, Pittsburgh, PA 15240, USA
    Int J Antimicrob Agents 25:302-7. 2005

Collaborators

Detail Information

Publications48

  1. ncbi request reprint Distribution of Legionella species and serogroups isolated by culture in patients with sporadic community-acquired legionellosis: an international collaborative survey
    Victor L Yu
    Veterans Affairs Medical Center, Infectious Disease Section, Pittsburgh, Pennsylvania 15240, USA
    J Infect Dis 186:127-8. 2002
    ..9%) and L. bozemanii (2.4%), followed by L. micdadei, L. dumoffii, L. feeleii, L. wadsworthii, and L. anisa (2.2% combined). L. longbeachae constituted 30.4% of the community-acquired Legionella isolates in Australia and New Zealand...
  2. ncbi request reprint An international prospective study of pneumococcal bacteremia: correlation with in vitro resistance, antibiotics administered, and clinical outcome
    Victor L Yu
    Division of Infectious Disease, University of Pittsburgh, PA, USA
    Clin Infect Dis 37:230-7. 2003
    ..beta-Lactam antibiotics should still be useful for treatment of pneumococcal infections that do not involve cerebrospinal fluid, regardless of in vitro susceptibility, as determined by current NCCLS breakpoints...
  3. ncbi request reprint Staphylococcus aureus bacteremia: recurrence and the impact of antibiotic treatment in a prospective multicenter study
    Feng Yee Chang
    VA Medical Center, Infectious Disease Section, University Drive C, Pittsburgh, PA 15240, USA
    Medicine (Baltimore) 82:333-9. 2003
    ..Duration of antistaphylococcal therapy was not associated with relapse, but type of antibiotic therapy was. Nafcillin was superior to vancomycin in efficacy in patients with MSSA bacteremia...
  4. ncbi request reprint Antibiotic therapy for Klebsiella pneumoniae bacteremia: implications of production of extended-spectrum beta-lactamases
    David L Paterson
    Infectious Disease Section, VA Medical Center, Pittsburgh, Pennsylvania 15240, USA
    Clin Infect Dis 39:31-7. 2004
    ..Antibiotic choice is particularly important in seriously ill patients with infections due to ESBL-producing K. pneumoniae...
  5. pmc Virulence characteristics of Klebsiella and clinical manifestations of K. pneumoniae bloodstream infections
    Victor L Yu
    University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Emerg Infect Dis 13:986-93. 2007
    ..001). Differences in clinical features of bacteremic infection with K. pneumoniae are due to the virulence factors expressed by the organism...
  6. ncbi request reprint Role of environmental surveillance in determining the risk of hospital-acquired legionellosis: a national surveillance study with clinical correlations
    Janet E Stout
    VA Pittsburgh Healthcare System, Pittsburgh, PA, USA
    Infect Control Hosp Epidemiol 28:818-24. 2007
    ..None of these hospitals had previously experienced endemic hospital-acquired Legionella pneumonia...
  7. ncbi request reprint Effect of pipe corrosion scales on chlorine dioxide consumption in drinking water distribution systems
    Zhe Zhang
    Department of Civil and Environmental Engineering, School of Engineering, University of Pittsburgh, 943 Benedum Hall, Pittsburgh, PA 15261, USA
    Water Res 42:129-36. 2008
    ..Based on these results, it can be concluded that the corrosion scale will cause much more significant ClO(2) loss in corroded iron pipes of the distribution system than the total organic carbon that may be present in finished water...
  8. ncbi request reprint Isolation of Staphylococcus aureus from the urinary tract: association of isolation with symptomatic urinary tract infection and subsequent staphylococcal bacteremia
    Robert R Muder
    Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15240, USA
    Clin Infect Dis 42:46-50. 2006
    ..The significance of staphylococcal bacteriuria is uncertain. We hypothesized that S. aureus is a urinary pathogen and that colonized urine could be a source of future staphylococcal infection...
  9. doi request reprint Computer keyboard covers impregnated with a novel antimicrobial polymer significantly reduce microbial contamination
    Natalie N D'Antonio
    Special Pathogens Laboratory, Pittsburgh, PA, USA
    Am J Infect Control 41:337-9. 2013
    ..This study aimed to determine whether plastic keyboard covers containing HM 4100 effectively minimize the survival of bacterial species commonly present on health care environmental surfaces...
  10. ncbi request reprint Comparative activity of quinolones, macrolides and ketolides against Legionella species using in vitro broth dilution and intracellular susceptibility testing
    Janet E Stout
    VA Pittsburgh Healthcare System, VA Medical Center, Infectious Disease Section, University Drive C, Pittsburgh, PA 15240, USA
    Int J Antimicrob Agents 25:302-7. 2005
    ..The rank order of intracellular activity against L. pneumophila serogroup 1 was quinolones>ketolides>macrolides. Clinical trials to determine the clinical efficacy of ketolides for the treatment of Legionnaires' disease are warranted...
  11. ncbi request reprint Safety and efficacy of chlorine dioxide for Legionella control in a hospital water system
    Zhe Zhang
    Department of Civil and Environmental Engineering, School of Engineering, University of Pittsburgh, Pittsburgh, PA, USA
    Infect Control Hosp Epidemiol 28:1009-12. 2007
    ..Use of chlorine dioxide was safe, based on Environmental Protection Agency limits regarding maximum concentrations of chlorine dioxide and chlorite...
  12. doi request reprint Revisiting the hand wipe versus gel rub debate: is a higher-ethanol content hand wipe more effective than an ethanol gel rub?
    Natalie N D'Antonio
    Special Pathogens Laboratory, Pittsburgh, PA, USA
    Am J Infect Control 38:678-82. 2010
    ..The objective of this study was to determine whether a hand wipe with higher ethanol content (65.9%) is as effective as an ethanol hand rub or antimicrobial soap in removing bacteria and spores from hands...
  13. doi request reprint Rapid diagnostic testing for community-acquired pneumonia: can innovative technology for clinical microbiology be exploited?
    Victor L Yu
    University of Pittsburgh and Special Pathogens Laboratory, Pittsburgh, PA 15219, USA
    Chest 136:1618-21. 2009
    ..To reduce antimicrobial overuse with subsequent antimicrobial resistance, these basic principles must be applied in concert with traditional and newer tests in the clinical microbiology laboratory...
  14. ncbi request reprint Quantitative cultures for diagnosing ventilator-associated pneumonia: a critique
    Shigeki Fujitani
    Infectious Disease Section, West Los Angeles Healthcare Center, VA Greater Los Angeles Healthcare System, Los Angeles, California, USA
    Clin Infect Dis 43:S106-13. 2006
    ..The variability in both the methods and reference criteria in the studies reviewed show that the quantitation approach is neither standardized nor evidence based...
  15. doi request reprint Outcomes of central nervous system cryptococcosis vary with host immune function: results from a multi-center, prospective study
    M Hong Nguyen
    The University of Florida, College of Medicine, Gainesville, FL, USA
    J Infect 61:419-26. 2010
    ..Central nervous system (CNS) cryptococcosis is most commonly encountered among HIV-infected and other immunosuppressed hosts but is less well-characterized among non-immunosuppressed patients...
  16. doi request reprint Pneumonia due to Pseudomonas aeruginosa: part II: antimicrobial resistance, pharmacodynamic concepts, and antibiotic therapy
    Hsin Yun Sun
    Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
    Chest 139:1172-85. 2011
    ....
  17. doi request reprint Pneumonia due to Pseudomonas aeruginosa: part I: epidemiology, clinical diagnosis, and source
    Shigeki Fujitani
    Department of Emergency and Critical Care Medicine, St Marianna University, Kanagawa, Japan
    Chest 139:909-19. 2011
    ..The source of the P aeruginosa may be endogenous (from respiratory or GI tract colonization) or exogenous from tap water in hospital-acquired pneumonia. The latter source is amenable to preventive measures...
  18. ncbi request reprint Legionnaires' disease in long-term care facilities: overview and proposed solutions
    Meena H Seenivasan
    Department of Veterans Affairs Pittsburgh Healthcare System and University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    J Am Geriatr Soc 53:875-80. 2005
    ..pneumophila serogroup 1 be found...
  19. ncbi request reprint Linezolid-associated peripheral and optic neuropathy, lactic acidosis, and serotonin syndrome
    Masashi Narita
    Infectious Disease Section, University of Pittsburgh, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, Pennsylvania 15240, USA
    Pharmacotherapy 27:1189-97. 2007
    ..Linezolid should be discontinued immediately in patients experiencing these adverse effects. Patients receiving linezolid for more than 28 days should be monitored for signs of peripheral and optic neuropathy...
  20. ncbi request reprint Experiences of the first 16 hospitals using copper-silver ionization for Legionella control: implications for the evaluation of other disinfection modalities
    Janet E Stout
    Special Pathogens Laboratory, Veterans Affairs Medical Center, Pittsburg, Pennsylvania 15240, USA
    Infect Control Hosp Epidemiol 24:563-8. 2003
    ..A standardized, evidence-based approach to assist hospitals with decision making concerning the possible purchase of a disinfection system is presented...
  21. ncbi request reprint Levofloxacin efficacy in the treatment of community-acquired legionellosis
    Victor L Yu
    VAMC and University of Pittsburgh, Pittsburgh, PA, USA
    Chest 125:2135-9. 2004
    ..Even fewer studies have applied rigorous criteria for diagnosis of community-acquired Legionnaires disease, including culture of respiratory secretions on selective media...
  22. ncbi request reprint International prospective study of Klebsiella pneumoniae bacteremia: implications of extended-spectrum beta-lactamase production in nosocomial Infections
    David L Paterson
    Veterans Affairs Medical Center, Pittsburgh, Pennsylvania 15240, USA
    Ann Intern Med 140:26-32. 2004
    ..Commonly encountered nosocomially acquired gram-negative bacteria, especially Klebsiella pneumoniae, produce extended-spectrum beta-lactamases (ESBLs) as an antibiotic resistance mechanism...
  23. doi request reprint Prospective observational study of chronic rhinosinusitis: environmental triggers and antibiotic implications
    Berrylin J Ferguson
    Department of Otolaryngology, University of Pittsburgh, Pennsylvania, USA
    Clin Infect Dis 54:62-8. 2012
    ..We examined differences in clinical manifestations and underlying conditions in patients with symptoms typical for CRS. CT scan abnormality of the sinuses was the gold standard for diagnosis of CRS...
  24. ncbi request reprint Legionnaires's disease in a transplant recipient acquired from the patient's home: implications for management
    Nina Singh
    VA Medical Center, University of Pittsburgh, PA, USA
    Transplantation 74:755-6. 2002
  25. ncbi request reprint Diagnosis of ventilator-associated pneumonia: focus on nonbronchoscopic techniques (nonbronchoscopic bronchoalveolar lavage, including mini-BAL, blinded protected specimen brush, and blinded bronchial sampling) and endotracheal aspirates
    Shigeki Fujitani
    Department of Critical Care Medicine, University of Pittsburgh, PA 15240, USA
    J Intensive Care Med 21:17-21. 2006
    ..Pending future studies, use of endotracheal aspirates without the use of quantitation seems to be a reasonable approach for clinicians who are not committed to an invasive procedure...
  26. ncbi request reprint Infection due to Legionella species other than L. pneumophila
    Robert R Muder
    Infectious Diseases Section, VA Pittsburgh Healthcare System and University of Pittsburgh School of Medicine, Pittsburgh, PA 15240, USA
    Clin Infect Dis 35:990-8. 2002
    ..Application of appropriate culture methodology to the etiologic diagnosis of pneumonia is needed to further define the role of these organisms in disease in humans...
  27. doi request reprint Mycobacterium monacense: a mycobacterial pathogen that causes infection of the hand
    Aurele Taieb
    Department of Surgery, Division of Plastic and Reconstructive Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    J Hand Surg Am 33:94-6. 2008
    ..The organism was identified as Mycobacterium monacense, a newly described species. The patient was cured with a 6-week course of clarithromycin and levofloxacin...
  28. ncbi request reprint Similar hematologic effects of long-term linezolid and vancomycin therapy in a prospective observational study of patients with orthopedic infections
    Nalini Rao
    Division of Infectious Disease, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15232, USA
    Clin Infect Dis 38:1058-64. 2004
    ..In conclusion, hematologic effects were detectable through weekly monitoring and were reversible; therefore, concern about myelosuppression need not preclude linezolid use for orthopedic infections requiring long-term therapy...
  29. ncbi request reprint Severing the Gordian knot of prevention of cytomegalovirus in liver transplant recipients: the principle is the sword
    Nina Singh
    Veterans Affairs Medical Center Infectious Diseases Section, Pittsburgh, PA 15240, USA
    Liver Transpl 11:891-4. 2005
  30. ncbi request reprint A prospective multicenter study of Staphylococcus aureus bacteremia: incidence of endocarditis, risk factors for mortality, and clinical impact of methicillin resistance
    Feng Yee Chang
    VA Medical Center, Infectious Disease Section, University Drive C, Pittsburgh, PA 15240, USA
    Medicine (Baltimore) 82:322-32. 2003
    ..MRSA as the infecting organism should be added to the list of risk factors for consideration of valvular resection in cases of endocarditis...
  31. doi request reprint Guidelines for hospital-acquired pneumonia and health-care-associated pneumonia: a vulnerability, a pitfall, and a fatal flaw
    Victor L Yu
    Special Pathogens Laboratory and Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA
    Lancet Infect Dis 11:248-52. 2011
    ..Emphasis should be placed on defining the microbial cause of the pneumonia rather than reflex administration of empirical combination therapy...
  32. doi request reprint Community-acquired legionnaires disease: implications for underdiagnosis and laboratory testing
    Victor L Yu
    Clin Infect Dis 46:1365-7. 2008
  33. pmc Community-acquired Klebsiella pneumoniae bacteremia: global differences in clinical patterns
    Wen Chien Ko
    National Cheng Kung University Medical College, Taiwan
    Emerg Infect Dis 8:160-6. 2002
    ..A distinctive form of K. pneumoniae infection, often causing liver abscess, was identified, almost exclusively in Taiwan...
  34. ncbi request reprint Streptococcus pneumoniae bacteraemia: pharmacodynamic correlations with outcome and macrolide resistance--a controlled study
    Jerome J Schentag
    CPL Associates, LLC, 3980 Sheridan Drive, Suite 501, Amherst, NY 14226 1727, USA
    Int J Antimicrob Agents 30:264-9. 2007
    ....
  35. ncbi request reprint Severe pneumococcal pneumonia: new strategies for management
    Christine C C Chiou
    Department of Pediatrics, Veterans General Hospital Kaohsiung, Kaohsiung, Taiwan
    Curr Opin Crit Care 12:470-6. 2006
    ..Bacteremic pneumococcal pneumonia is an advanced stage of severe pneumococcal pneumonia. Improvement in the management of bacteremic pneumococcal pneumonia has the potential for improving the survival for severe pneumococcal pneumonia...
  36. ncbi request reprint No impact of penicillin resistance on mortality
    Keith P Klugman
    Clin Infect Dis 43:261; author reply 261-2. 2006
  37. ncbi request reprint The role of Klebsiella pneumoniae in lung abscesses: a geographic phenomenon (for now!)
    Victor L Yu
    Clin Infect Dis 42:152-3; author reply 153-4. 2006
  38. ncbi request reprint Combination antibiotic therapy lowers mortality among severely ill patients with pneumococcal bacteremia
    Larry M Baddour
    Mayo Clinic, Rochester, NY, USA
    Am J Respir Crit Care Med 170:440-4. 2004
    ..Combination antibiotic therapy improved survival among critically ill patients with bacteremic pneumococcal illness...
  39. ncbi request reprint Infection by drug-resistant Streptococcus pneumoniae is not linked to increased mortality
    Victor L Yu
    Clin Infect Dis 39:1086-7; author reply 1087-8. 2004
  40. ncbi request reprint Bacteraemic pneumococcal pneumonia: impact of HIV on clinical presentation and outcome
    Charles Feldman
    Division of Pulmonology, Department of Medicine, Johannesburg Hospital, University of the Witwatersrand, Medical School, 7 York Road, Parktown 2193, Johannesburg, South Africa
    J Infect 55:125-35. 2007
    ....
  41. ncbi request reprint Hospital-acquired legionellosis: solutions for a preventable infection
    Miguel Sabria
    Hospital Universitario Germans Trias I Pujol and the Autonomous University of Barcelona, Badalona, Spain
    Lancet Infect Dis 2:368-73. 2002
    ..There is a need for public-health agencies to educate the public and media that discovery of cases identifies those hospitals as providers of superior care, and that such hospitals are not negligent...
  42. ncbi request reprint Legionella anisa and hospital water systems
    Victor L Yu
    J Infect Chemother 10:133; author reply 134. 2004
  43. ncbi request reprint Legionnaires disease and the updated IDSA guidelines for community-acquired pneumonia
    Victor L Yu
    Clin Infect Dis 39:1734-7; author reply 1737-8. 2004
  44. ncbi request reprint Management of nonsevere pneumonia in military trainees with the urinary antigen test for Streptococcus pneumoniae: an innovative approach to targeted therapy
    Igor A Guchev
    Pulmonary Medicine Department, Smolensk Military Hospital, Smolensk, Russia
    Clin Infect Dis 40:1608-16. 2005
    ..Our purpose was to assess the usefulness of a strategy of targeted antimicrobial therapy based on the results of a rapid urinary antigen test for S. pneumoniae...
  45. pmc Fluconazole MIC and the fluconazole dose/MIC ratio correlate with therapeutic response among patients with candidemia
    Cornelius J Clancy
    University of Florida College of Medicine, P O Box 100277, JHMHC, Gainesville, FL 32610, USA
    Antimicrob Agents Chemother 49:3171-7. 2005
    ..In clinical practice, dose/MIC ratio might prove easier to interpret than breakpoint MICs, since it quantitates the effects of increasing fluconazole doses that are alluded to in the S-DD designation...
  46. ncbi request reprint Preemptive therapy for cytomegalovirus
    Nina Singh
    Liver Transpl 12:327. 2006
  47. ncbi request reprint Problem pathogens: paediatric legionellosis--implications for improved diagnosis
    David Greenberg
    Soroka University Medical Center, Beer Sheeva, Israel
    Lancet Infect Dis 6:529-35. 2006
    ..As legionella diagnostic tests become more widely applied, we predict that legionellosis may appear as an emerging infectious disease in children...
  48. pmc Negative effect of high pH on biocidal efficacy of copper and silver ions in controlling Legionella pneumophila
    Yu Sen E Lin
    Graduate Institute of Environmental Education, National Kaohsiung Normal University, Kaohsiung, Taiwan
    Appl Environ Microbiol 68:2711-5. 2002
    ..Precipitation of insoluble copper complexes was observed at a pH above 6.0. These results suggest that pH may be an important factor in the efficacy of copper-silver ionization in controlling Legionella in water systems...