Mimi C Yu

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. ncbi request reprint Plasma isoflavone levels versus self-reported soy isoflavone levels in Asian-American women in Los Angeles County
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles 90089 9175, USA
    Carcinogenesis 25:77-81. 2004
  2. ncbi request reprint Tea intake, COMT genotype, and breast cancer in Asian-American women
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA 90089, USA
    Cancer Res 63:7526-9. 2003
  3. ncbi request reprint Alkylaniline-hemoglobin adducts and risk of non-smoking-related bladder cancer
    Jinping Gan
    Biological Engineering Division, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    J Natl Cancer Inst 96:1425-31. 2004
  4. ncbi request reprint Tea and circulating estrogen levels in postmenopausal Chinese women in Singapore
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90089 9175, USA
    Carcinogenesis 26:976-80. 2005
  5. pmc Genetic polymorphisms of epidermal growth factor in relation to risk of hepatocellular carcinoma: two case-control studies
    Jian Min Yuan
    Division of Cancer Control and Population Sciences, University of Pittsburgh Cancer Institute, UPMC Cancer Pavilion, Suite 4C, 5150 Centre Avenue, Pittsburgh, PA 15232, USA
    BMC Gastroenterol 13:32. 2013
  6. ncbi request reprint Epidemiology of nasopharyngeal carcinoma
    Mimi C Yu
    Department of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA
    Semin Cancer Biol 12:421-9. 2002
  7. ncbi request reprint Environmental factors and risk for hepatocellular carcinoma
    Mimi C Yu
    Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Gastroenterology 127:S72-8. 2004
  8. ncbi request reprint Arylamine exposures and bladder cancer risk
    Mimi C Yu
    Keck School of Medicine, USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA
    Mutat Res 506:21-8. 2002
  9. ncbi request reprint Carotenoids/vitamin C and smoking-related bladder cancer
    J Esteban Castelao
    USC Norris Comprehensive Cancer Center, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90089 9181, USA
    Int J Cancer 110:417-23. 2004
  10. ncbi request reprint A new single nucleotide polymorphism in the insulin-like growth factor I regulatory region associates with colorectal cancer risk in singapore chinese
    Hui Lee Wong
    University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA 90089, USA
    Cancer Epidemiol Biomarkers Prev 14:144-51. 2005

Detail Information

Publications90

  1. ncbi request reprint Plasma isoflavone levels versus self-reported soy isoflavone levels in Asian-American women in Los Angeles County
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles 90089 9175, USA
    Carcinogenesis 25:77-81. 2004
    ..These results further strengthen our previous observation of an inverse association between soy intake and breast cancer risk in the Los Angeles Asian Breast Cancer Study...
  2. ncbi request reprint Tea intake, COMT genotype, and breast cancer in Asian-American women
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA 90089, USA
    Cancer Res 63:7526-9. 2003
    ..Reduction in risk was strongest among persons who had the low activity COMT alleles, suggesting these individuals were less efficient in eliminating tea catechins and may derive the most benefit from these compounds...
  3. ncbi request reprint Alkylaniline-hemoglobin adducts and risk of non-smoking-related bladder cancer
    Jinping Gan
    Biological Engineering Division, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    J Natl Cancer Inst 96:1425-31. 2004
    ..Low levels of 4-ABP exposure have been associated with non-smoking-related bladder cancer. Other arylamine compounds coming from as yet unidentified environmental sources may also be human bladder carcinogens...
  4. ncbi request reprint Tea and circulating estrogen levels in postmenopausal Chinese women in Singapore
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90089 9175, USA
    Carcinogenesis 26:976-80. 2005
    ..Larger studies are needed to confirm results from this cross-sectional study and to better understand the potentially differing effect of black and green tea on circulating estrogen levels and ultimately on the risk of breast cancer...
  5. pmc Genetic polymorphisms of epidermal growth factor in relation to risk of hepatocellular carcinoma: two case-control studies
    Jian Min Yuan
    Division of Cancer Control and Population Sciences, University of Pittsburgh Cancer Institute, UPMC Cancer Pavilion, Suite 4C, 5150 Centre Avenue, Pittsburgh, PA 15232, USA
    BMC Gastroenterol 13:32. 2013
    ..A polymorphism in the EGF gene (61A > G) results in elevation of EGF in liver tissues and blood. Epidemiological data are sparse on the possible association between EGF genetic polymorphism and HCC risk...
  6. ncbi request reprint Epidemiology of nasopharyngeal carcinoma
    Mimi C Yu
    Department of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA
    Semin Cancer Biol 12:421-9. 2002
    ..Other recognized risk factors for NPC are cigarette smoking, and occupational exposure to formaldehyde and wood dust...
  7. ncbi request reprint Environmental factors and risk for hepatocellular carcinoma
    Mimi C Yu
    Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Gastroenterology 127:S72-8. 2004
    ..In summary, risk factors for HCC are identifiable in most patients and primarily are associated with chronic hepatic injury...
  8. ncbi request reprint Arylamine exposures and bladder cancer risk
    Mimi C Yu
    Keck School of Medicine, USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA
    Mutat Res 506:21-8. 2002
    ..Furthermore, women may experience higher bladder cancer risk than men from comparable arylamine exposure, possibly due in part to women's higher propensity for arylamine activation relative to men...
  9. ncbi request reprint Carotenoids/vitamin C and smoking-related bladder cancer
    J Esteban Castelao
    USC Norris Comprehensive Cancer Center, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90089 9181, USA
    Int J Cancer 110:417-23. 2004
    ..The carotenoid-bladder cancer association was not affected by the GSTM1, GSTT1 and GSTP1 genotypes...
  10. ncbi request reprint A new single nucleotide polymorphism in the insulin-like growth factor I regulatory region associates with colorectal cancer risk in singapore chinese
    Hui Lee Wong
    University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA 90089, USA
    Cancer Epidemiol Biomarkers Prev 14:144-51. 2005
    ..In conclusion, we report a novel SNP in the IGF-I regulatory region that is associated with colorectal cancer risk...
  11. doi request reprint Dietary patterns and breast cancer risk in Asian American women
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90089, USA
    Am J Clin Nutr 89:1145-54. 2009
    ..The role of diet as a cause of breast cancer in Asian Americans has not been adequately studied...
  12. pmc Dietary isothiocyanates, glutathione S-transferase M1 (GSTM1), and lung cancer risk in African Americans and Caucasians from Los Angeles County, California
    Catherine L Carpenter
    David Geffen School of Medicine, University of California, Los Angeles, CA 90095 1742, USA
    Nutr Cancer 61:492-9. 2009
    ..52). Reduced lung cancer risk with higher isothiocyanate intake may be slightly stronger among subjects with deletion of GSTM1...
  13. ncbi request reprint Marine n-3 fatty acid intake, glutathione S-transferase polymorphisms and breast cancer risk in post-menopausal Chinese women in Singapore
    Manuela Gago-Dominguez
    USC Norris Comprehensive Cancer Center, Keck School of Medicine of the University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033 0800, USA
    Carcinogenesis 25:2143-7. 2004
    ..36, 95% CI = 0.14, 0.94). A similar relationship was observed among women with the combined GSTT1 null and GSTP1 AB/BB genotypes (OR = 0.26, 95% CI = 0.08, 0.78)...
  14. pmc Polyunsaturated fatty acids, DNA repair single nucleotide polymorphisms and colorectal cancer in the Singapore Chinese Health Study
    Mariana C Stern
    Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA
    J Nutrigenet Nutrigenomics 2:273-9. 2009
    ..003). Our results suggest a positive association between high intake of marine n-3 PUFA and rectal cancer risk among carriers of at least one PARP codon 762 Ala allele (odds ratio=1.7, 95% confidence interval=1.1-2.7)...
  15. ncbi request reprint Beta-cryptoxanthin and lung cancer in Shanghai, China--an examination of potential confounding with cigarette smoking using urinary cotinine as a biomarker for true tobacco exposure
    Daniel O Stram
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Nutr Cancer 57:123-9. 2007
    ....
  16. ncbi request reprint Associations between soy, diet, reproductive factors, and mammographic density in Singapore Chinese women
    Giske Ursin
    University of Southern California, Los Angeles, CA 90089, USA
    Nutr Cancer 56:128-35. 2006
    ..Our results suggest that the effect of soy intake on percent mammographic density is moderate but possibly of clinical relevance...
  17. doi request reprint Anthropometric, dietary, and hormonal correlates of serum adiponectin in Asian American women
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90089, USA
    Nutr Cancer 63:549-57. 2011
    ..0001) and the ratios of total testosterone (T)/total estradiol (E2) (P trend <0.004) after adjustment for BMI and WHR. Confirmation of our findings on green tea and adiponectin is needed...
  18. pmc Green tea, soy, and mammographic density in Singapore Chinese women
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    Cancer Epidemiol Biomarkers Prev 17:3358-65. 2008
    ..52). Our findings suggest that both regular green tea and high soy intake may have beneficial effects on the breast; the effect of green tea on PMD may be stronger than the effect of soy...
  19. ncbi request reprint Green tea intake, ACE gene polymorphism and breast cancer risk among Chinese women in Singapore
    Jian Min Yuan
    USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, MC 9175, Los Angeles, CA 90089 9181, USA
    Carcinogenesis 26:1389-94. 2005
    ..The findings of the present study highlight the importance of genetically determined factors in evaluating the role of green tea intake in the development of breast cancer...
  20. ncbi request reprint Diabetes and risk of breast cancer in Asian-American women
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90089, USA
    Carcinogenesis 28:1561-6. 2007
    ..08) than women without such a history after adjusting for BMI and WHR. Our results support the hypothesis that diabetes may have a role in the development of breast cancer, influencing risk via both sex hormone and insulin pathways...
  21. pmc Genetic variation in peroxisome proliferator-activated receptor gamma, soy, and mammographic density in Singapore Chinese women
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Ave, Norris Cancer Center, Los Angeles, CA 90089, USA
    Cancer Epidemiol Biomarkers Prev 21:635-44. 2012
    ..We investigated the interrelations of soy, PPARγ, and mammographic density, a biomarker of breast cancer risk in a cross-sectional study of 2,038 women who were members of the population-based Singapore Chinese Health Study Cohort...
  22. ncbi request reprint Body size, hormone therapy and risk of breast cancer in Asian-American women
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
    Int J Cancer 120:844-52. 2007
    ..017). The increased risk associated with high body weight was observed irrespective of HT use. Use of HT and high body size might have contributed to the rapid increase of breast cancer in Asian-Americans...
  23. ncbi request reprint Prediagnostic levels of serum micronutrients in relation to risk of gastric cancer in Shanghai, China
    Jian Min Yuan
    Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, MC 9175, 1441 Eastlake Avenue, Los Angeles, CA 90033 0800, USA
    Cancer Epidemiol Biomarkers Prev 13:1772-80. 2004
    ..The present study implicates that dietary carotenes, lycopene, and vitamin C are potential chemopreventive agents for gastric cancer in humans...
  24. ncbi request reprint Synergism of alcohol, diabetes, and viral hepatitis on the risk of hepatocellular carcinoma in blacks and whites in the U.S
    Jian Min Yuan
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles 90089 9176, USA
    Cancer 101:1009-17. 2004
    ..Heavy alcohol consumption, viral hepatitis, and diabetes are risk factors for hepatocellular carcinoma (HCC). However, to the authors' knowledge, the information concerning their interaction effect in patients with risk of HCC is sparse...
  25. ncbi request reprint Vitamin D receptor start codon polymorphism and colorectal cancer risk: effect modification by dietary calcium and fat in Singapore Chinese
    Hui Lee Wong
    USC Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
    Carcinogenesis 24:1091-5. 2003
    ..5-fold increased risk that was statistically significant. There was little evidence of a VDR genotype-colorectal cancer association among subjects with higher than median values of either dietary fat or calcium...
  26. ncbi request reprint DNA repair single-nucleotide polymorphisms in colorectal cancer and their role as modifiers of the effect of cigarette smoking and alcohol in the Singapore Chinese Health Study
    Mariana C Stern
    Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Avenue, Room 5421A, Los Angeles, CA 90089, USA
    Cancer Epidemiol Biomarkers Prev 16:2363-72. 2007
    ..8; 95% CI, 1.0-8.1). Our results support a role for reactive oxygen species as relevant genotoxins that may account for the effects of both smoking and alcohol on colorectal cancer risk...
  27. pmc Sleep duration, melatonin and breast cancer among Chinese women in Singapore
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    Carcinogenesis 29:1244-8. 2008
    ..However, data are inconclusive from the three studies conducted in Western populations on sleep duration and breast cancer risk...
  28. pmc DNA methylation as a biomarker for cardiovascular disease risk
    Myungjin Kim
    Department of Surgery, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America
    PLoS ONE 5:e9692. 2010
    ..This may reflect a reduced systemic remethylation capacity, which would be expected to cause decreased genomic DNA methylation in peripheral blood leukocytes (PBL)...
  29. ncbi request reprint Dietary cryptoxanthin and reduced risk of lung cancer: the Singapore Chinese Health Study
    Jian Min Yuan
    Department of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, California 90033 0800, USA
    Cancer Epidemiol Biomarkers Prev 12:890-8. 2003
    ..The present study lends additional credence to prior experimental and epidemiological data in support of the hypothesis that dietary beta-cryptoxanthin is a chemopreventive agent for lung cancer in humans...
  30. ncbi request reprint Dietary soy and increased risk of bladder cancer: the Singapore Chinese Health Study
    Can Lan Sun
    USC Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, California 90089, USA
    Cancer Epidemiol Biomarkers Prev 11:1674-7. 2002
    ..To our knowledge, this is the first epidemiological report on the effect of dietary soy on bladder cancer risk...
  31. pmc Genetic variation in transforming growth factor beta 1 and mammographic density in Singapore Chinese women
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Cancer Res 73:1876-82. 2013
    ..Our data support that TGFB1 genetic variation may be an important genetic determinant of mammographic density measure that predicts breast cancer risk, particularly in nulliparous women...
  32. ncbi request reprint Permanent hair dyes and bladder cancer: risk modification by cytochrome P4501A2 and N-acetyltransferases 1 and 2
    Manuela Gago-Dominguez
    USC Norris Comprehensive Cancer Center, Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033 0800, USA
    Carcinogenesis 24:483-9. 2003
    ..On the other hand, individuals of NAT1*10 genotype exhibited no such associations...
  33. pmc Combination of molecular alterations and smoking intensity predicts bladder cancer outcome: a report from the Los Angeles Cancer Surveillance Program
    Anirban P Mitra
    Department of Pathology, University of Southern California, Los Angeles, California, USA
    Cancer 119:756-65. 2013
    ....
  34. ncbi request reprint Comparison of prostate-specific antigen and hormone levels among men in Singapore and the United States
    Iona Cheng
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, USC Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, Los Angeles, CA, 90089 9175, USA
    Cancer Epidemiol Biomarkers Prev 14:1692-6. 2005
    ..Given that the overall mortality rate of prostate cancer in Singapore is low, these undiagnosed cancers may be of nonaggressive type. Alternatively, PSA may be a poor marker of prostate cancer in this low-risk population...
  35. pmc Sleep duration, spot urinary 6-sulfatoxymelatonin levels and risk of breast cancer among Chinese women in Singapore
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90089 9175, USA
    Int J Cancer 132:891-6. 2013
    ..Melatonin levels derived from randomly timed spot urine are unrelated to breast cancer. Randomly timed, spot urine-derived melatonin levels are noninformative as surrogates of nocturnal melatonin production...
  36. ncbi request reprint Environmental tobacco smoke and bladder cancer risk in never smokers of Los Angeles County
    Xuejuan Jiang
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, California, USA
    Cancer Res 67:7540-5. 2007
    ..ETS exposure was associated with neither bladder cancer risk nor 4-ABP-Hb adduct levels in male lifelong nonsmokers. In conclusion, ETS is a risk factor for bladder cancer in women who were lifelong nonusers of any tobacco products...
  37. doi request reprint Hormone metabolism genes and mammographic density in Singapore Chinese women
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Cancer Epidemiol Biomarkers Prev 22:984-6. 2013
    ..We investigated the association between genetic variation in the hormone metabolism and signaling pathway and mammographic density, a strong predictor of breast cancer risk...
  38. ncbi request reprint Dietary soy and increased risk of bladder cancer: a prospective cohort study of men in Shanghai, China
    Can Lan Sun
    USC Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, CA 90033 9176, USA
    Int J Cancer 112:319-23. 2004
    ..The soy-bladder cancer risk associations in smokers and non-smokers were comparable. The soy-bladder cancer relationship became stronger when the analysis was restricted to subjects with 2 or more years of follow-up...
  39. ncbi request reprint Green tea and risk of breast cancer in Asian Americans
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
    Int J Cancer 106:574-9. 2003
    ..In summary, our results point to an important role of both green tea and soy intake in relation to breast cancer risk in Asian-American women...
  40. ncbi request reprint HSD17B1 and CYP17 polymorphisms and breast cancer risk among Chinese women in Singapore
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
    Int J Cancer 104:450-7. 2003
    ..41, 95% CI=1.56-3.72; RR=4.39, 95% CI=1.71-11.30, respectively). The latter gene-parity effects were especially pronounced in postmenopausal women...
  41. ncbi request reprint Lipid peroxidation: a novel and unifying concept of the etiology of renal cell carcinoma (United States)
    Manuela Gago-Dominguez
    Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles 90089 9176, USA
    Cancer Causes Control 13:287-93. 2002
    ..Our hypothesis may also explain the roles of other risk (oophorectomy/hysterectomy, parity, smoking, diabetes) and protective factors (dietary antioxidants) for renal cell cancer...
  42. ncbi request reprint Sex differential in methylation patterns of selected genes in Singapore Chinese
    Barbara Sarter
    Kenneth Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
    Hum Genet 117:402-3. 2005
    ..13 and 0.96, respectively). Our data suggest that gender is at least as strong a predictor of methylation level in the four genes under study as age, with males showing higher PMRs...
  43. ncbi request reprint Tea, hormone-related cancers and endogenous hormone levels
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA 90089 9175, USA
    Mol Nutr Food Res 50:160-9. 2006
    ..We pay special attention to some of the limitations of the human studies and discuss future research needs...
  44. ncbi request reprint GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer
    Eunjung Lee
    Department of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, CA 90089 9176, USA
    Cancer Res 66:7849-53. 2006
    ..82; P = 0.010). The use of GRP78 as a predictor for chemoresponsiveness and the potential interaction of GRP78 and/or the UPR pathways with taxanes warrant larger studies...
  45. ncbi request reprint A modified reduced-temperature antigen retrieval protocol effective for use with a polyclonal antibody to cyclooxygenase-2 (PG 27)
    Shan Rong Shi
    Department of Pathology, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    Appl Immunohistochem Mol Morphol 10:368-73. 2002
    ..In conclusion, use of the test battery approach allowed development of a modified antigen retrieval technique that provides a more reliable, much simpler approach for the demonstration of cyclooxygenase-2 in archival tissues...
  46. ncbi request reprint Urinary tea polyphenols in relation to gastric and esophageal cancers: a prospective study of men in Shanghai, China
    Can Lan Sun
    USC Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, 1441 Eastlake Avenue, Los Angeles, CA 90089 9176, USA
    Carcinogenesis 23:1497-503. 2002
    ..The present study provides direct evidence that tea polyphenols may act as chemopreventive agents against gastric and esophageal cancer development...
  47. ncbi request reprint Adolescent and adult soy intake and risk of breast cancer in Asian-Americans
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
    Carcinogenesis 23:1491-6. 2002
    ..These results show that high soy intake in childhood in Asian-Americans is associated with reduced breast cancer risk. Risk may be further reduced by intake as an adult...
  48. doi request reprint Cancer, culture, and health disparities: time to chart a new course?
    Marjorie Kagawa-Singer
    Department of Asian American Studies, Senior Editor, AAPI Nexus Journal, Los Angeles, California 90095 1772, USA
    CA Cancer J Clin 60:12-39. 2010
    ..The authors conclude with suggestions for clinical practice to eliminate the disconnection between evidence-based, quality, cancer care and its delivery to diverse population groups...
  49. ncbi request reprint A case-control study of cyclin D1 CCND1 870A-->G polymorphism and bladder cancer
    Victoria K Cortessis
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, MC 9175, Los Angeles, CA 90033, USA
    Carcinogenesis 24:1645-50. 2003
    ..90, 95% confidence interval 0.60-1.33). The null association was not appreciably modified by bladder cancer risk factors, including lifetime smoking history, or by histopathologic classification...
  50. ncbi request reprint Soy intake and other lifestyle determinants of serum estrogen levels among postmenopausal Chinese women in Singapore
    Anna H Wu
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90089, USA
    Cancer Epidemiol Biomarkers Prev 11:844-51. 2002
    ..Current smokers showed significantly higher E(2) levels (28%) than nonsmokers (P = 0.04). These findings are discussed in relation to the recent doubling of breast cancer incidence among Chinese women in Singapore...
  51. ncbi request reprint Detection of residual subclinical ovarian carcinoma after completion of adjuvant chemotherapy
    Mory Nouriani
    Division of Gynecologic Oncology, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    Clin Cancer Res 10:2681-6. 2004
    ..We hypothesized that this test, if added to second-look procedure protocols, could help determine whether residual disease is present or not in patients who have completed their adjuvant chemotherapy for ovarian carcinoma...
  52. ncbi request reprint Effect of reproductive hormones on ovarian epithelial tumors: II. Effect on angiogenic activity
    Chen Chen
    Deportment of Pathology USC Norris Comprehensive Concer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Cancer Biol Ther 1:307-12. 2002
    ..Therapeutic use of progestins may be most effective when administered in combination with an anti-angiogenic agent, at least against a subset of ovarian carcinomas...
  53. ncbi request reprint Hepatitis C in a Los Angeles public hepatitis clinic: demographic and biochemical differences associated with race-ethnicity
    Anne F Celona
    Keck School of Medicine, University of Southern California, Los Angeles, California 94115, USA
    Clin Gastroenterol Hepatol 2:459-62. 2004
    ..The goal of this study was to uncover possible racial-ethnic differences in hepatitis C presentation in an urban hepatitis clinic...
  54. ncbi request reprint Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels
    Binh N Trinh
    Department of Surgery, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, CA 90089 9176, USA
    Hum Genet 111:299-302. 2002
    ..These genetic determinants of plasma folate and homocysteine levels may be useful in identifying individuals at increased risk for cardiovascular disease...
  55. ncbi request reprint Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer
    Jan Stoehlmacher
    Department of Medical Oncology, University of Southern California Norris Comprehensive Cancer Center, Keck School of Medicine, Los Angeles, CA 90033, USA
    J Natl Cancer Inst 94:936-42. 2002
    ....
  56. ncbi request reprint Urinary biomarkers of tea polyphenols and risk of colorectal cancer in the Shanghai Cohort Study
    Jian Min Yuan
    The Cancer Center, University of Minnesota, 1300 South 2nd Street, Minneapolis, MN 55454, USA
    Int J Cancer 120:1344-50. 2007
    ..Urinary levels of tea polyphenols and their metabolites were not associated with rectal cancer risk. The present study supports the notion of tea catechins as chemopreventive agents against the development of colon cancer in humans...
  57. pmc Genetic determinants in the metabolism of bladder carcinogens in relation to risk of bladder cancer
    Jian Min Yuan
    The Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA
    Carcinogenesis 29:1386-93. 2008
    ..12-3.69, P = 0.02). The effect of NAT2 slow acetylation was even stronger in the presence of two or more null/low-activity GST genotypes. There were no associations between bladder cancer risk and NAT1 genotype or CYP1A2 phenotype...
  58. ncbi request reprint Nonsmoking-related arylamine exposure and bladder cancer risk
    Paul L Skipper
    Biological Engineering Division, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Cancer Epidemiol Biomarkers Prev 12:503-7. 2003
    ....
  59. pmc Differential effects of black versus green tea on risk of Parkinson's disease in the Singapore Chinese Health Study
    Louis C Tan
    Department of Neurology, National Neuroscience Institute, Singapore
    Am J Epidemiol 167:553-60. 2008
    ..Green tea drinking was unrelated to Parkinson's disease risk. Diet had no strong influence on risk. Ingredients of black tea other than caffeine appear to be responsible for the beverage's inverse association with Parkinson's disease...
  60. pmc Alcohol, tobacco, and diet in relation to esophageal cancer: the Shanghai Cohort Study
    Yunhua Fan
    The Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Nutr Cancer 60:354-63. 2008
    ..low consumers after adjustment for cigarette smoking, alcohol drinking, and other confounders...
  61. pmc Urinary total isothiocyanates and colorectal cancer: a prospective study of men in Shanghai, China
    Kristin A Moy
    The Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA
    Cancer Epidemiol Biomarkers Prev 17:1354-9. 2008
    ..25-0.83), respectively, for risk of colorectal cancer (P for trend = 0.006). The present study suggests that dietary ITCs may exert tumor inhibitory effects, especially during earlier stages of the multistage process of carcinogenesis...
  62. pmc Incense use and respiratory tract carcinomas: a prospective cohort study
    Jeppe T Friborg
    The Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA
    Cancer 113:1676-84. 2008
    ..Therefore, the relation between incense use and the risk of respiratory tract carcinomas was analyzed in a prospective cohort study...
  63. pmc Coffee, tea, and incident type 2 diabetes: the Singapore Chinese Health Study
    Andrew O Odegaard
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA
    Am J Clin Nutr 88:979-85. 2008
    ..Increasing coffee intake was inversely associated with risk of type 2 diabetes in populations of European descent; however, data from high-risk Asian populations are lacking as are data on tea intake in general...
  64. ncbi request reprint Diet, reproductive factors and lung cancer risk among Chinese women in Singapore: evidence for a protective effect of soy in nonsmokers
    Adeline Seow
    Department of Community, Occupational and Family Medicine, Faculty of Medicine MD3, National University of Singapore, 16 Medical Drive, 117597 Singapore
    Int J Cancer 97:365-71. 2002
    ..These findings are consistent with other evidence suggesting an involvement of estrogen-related pathways in lung cancer among non-smoking women...
  65. ncbi request reprint Dietary isothiocyanates, glutathione S-transferase polymorphisms and colorectal cancer risk in the Singapore Chinese Health Study
    Adeline Seow
    Department of Community, Occupational and Family Medicine, Faculty of Medicine, National University of Singapore, Singapore
    Carcinogenesis 23:2055-61. 2002
    ..Further, this gene-diet interaction may be important in studies evaluating the effect of risk-enhancing compounds in the colorectum...
  66. ncbi request reprint Angiotensin I-converting enzyme (ACE) gene polymorphism and breast cancer risk among Chinese women in Singapore
    Woon Puay Koh
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore 117597
    Cancer Res 63:573-8. 2003
    ..27-0.81). Our findings support experimental data implicating ACE and angiotensin II in breast cancer, and suggest that the renin-angiotensin system may serve as a therapeutic target for breast cancer treatment and prevention...
  67. ncbi request reprint Mammographic parenchymal patterns and self-reported soy intake in Singapore Chinese women
    Rupert W Jakes
    National Medical Research Council Clinical Trials and Epidemiology Research Unit, Singapore 169039
    Cancer Epidemiol Biomarkers Prev 11:608-13. 2002
    ..20-0.98). The association between high soy intake and a reduced risk of mammographic parenchymal patterns that are associated with high breast cancer risk may have important implications in breast cancer prevention...
  68. ncbi request reprint Insulin-like growth factor I, IGF-binding protein 3, and lung cancer risk in a prospective study of men in China
    Stephanie J London
    Epidemiology Branch and Laboratory of Pulmonary Pathobiology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    J Natl Cancer Inst 94:749-54. 2002
    ..In a prospective study of men in Shanghai, China, we examined the association between serum levels of IGF-I and IGFBP-3 and the subsequent risk of lung cancer...
  69. ncbi request reprint Green tea and black tea consumption in relation to colorectal cancer risk: the Singapore Chinese Health Study
    Can Lan Sun
    Division of Population Sciences, City of Hope National Medical Center and Beckman Research Institute, 1500 East Duarte Road, Duarte, CA 91010, USA
    Carcinogenesis 28:2143-8. 2007
    ..75, 95% CI = 1.24-2.46; P for trend < 0.0001). Irrespective of gender, intake of black tea was not associated with risk of colorectal cancer (RR = 0.92, 95% CI = 0.79-1.07) in this Asian population...
  70. pmc Morbidity and mortality in relation to smoking among women and men of Chinese ethnicity: the Singapore Chinese Health Study
    Anoop Shankar
    Department of Community, Occupational, and Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
    Eur J Cancer 44:100-9. 2008
    ..We examined the association among cigarette smoking, smoking cessation and a broad range of cancer incidence and all cause and cause-specific mortality in a population-based cohort of adults of Chinese ethnicity in Singapore...
  71. ncbi request reprint Tobacco smoking and urinary levels of 2-amino-9H-pyrido[2,3-b]indole in men of Shanghai, China
    Robert J Turesky
    Wadsworth Center, New York State Department of Health, Albany, New York, Empire State Plaza, P O Box 509, Albany, NY 12201 0509, USA
    Cancer Epidemiol Biomarkers Prev 16:1554-60. 2007
    ..Our data indicate that AalphaC represents a major HAA exposure in adult men of Shanghai, China, and that tobacco smoke is an important point source of their AalphaC exposure...
  72. ncbi request reprint Diabetes mellitus and risk of colorectal cancer in the Singapore Chinese Health Study
    Adeline Seow
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore
    J Natl Cancer Inst 98:135-8. 2006
    ..Our results support the hypothesis that hyperinsulinemia may play a role in colorectal carcinogenesis, even in a relatively lean population...
  73. ncbi request reprint Middle-aged and older Chinese men and women in Singapore who smoke have less healthy diets and lifestyles than nonsmokers
    Woon Puay Koh
    Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore
    J Nutr 135:2473-7. 2005
    ..Our results are consistent with findings among Western populations, and suggest that the unhealthy diet and lifestyle in smokers occur across diverse cultures...
  74. ncbi request reprint 249ser p53 mutation in the serum of black southern African patients with hepatocellular carcinoma
    Gerald C Kimbi
    MRC University Molecular Hepatology Research Unit, Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa
    J Gastroenterol Hepatol 20:1185-90. 2005
    ..No information is available from other regions. We therefore examined cell-free serum from HCC patients in southern Africa, where aflatoxin B(1) exposure ranges from very high to low levels...
  75. ncbi request reprint Effect of glutathione-S-transferase polymorphisms on the cancer preventive potential of isothiocyanates: an epidemiological perspective
    Adeline Seow
    Department of Community, Occupational and Family Medicine, National University of Singapore, 16 Medical Drive, MD3, Singapore 117597, Singapore
    Mutat Res 592:58-67. 2005
    ....
  76. ncbi request reprint Polymorphisms in angiotensin II type 1 receptor and angiotensin I-converting enzyme genes and breast cancer risk among Chinese women in Singapore
    Woon Puay Koh
    Department of Community, Occupational and Family Medicine, National University of Singapore, 16 Medical Drive, Singapore 117597, Singapore
    Carcinogenesis 26:459-64. 2005
    ..Our findings suggest that pharmacological inhibition of the angiotensin II effect by blockade of ACE and/or AGTR1 could be potential targets for the prevention and treatment of breast cancer...
  77. ncbi request reprint The effect of cyclin D1 (CCND1) G870A-polymorphism on breast cancer risk is modified by oxidative stress among Chinese women in Singapore
    Michela Ceschi
    Cancer Registry and Molecular Epidemiology, University Hospital, Vogelsangstrasse 10, 8091 Zurich, Switzerland
    Carcinogenesis 26:1457-64. 2005
    ..The results of this study are compatible with the hypothesis that the oxidant-antioxidant balance in cells is an important determinant of the direction of the cyclin D1 effect, leading either to cell proliferation or cell death...
  78. ncbi request reprint Effect of cytokine genotypes on the hepatitis B virus-hepatocellular carcinoma association
    Alexandra Nieters
    Department of Clinical Epidemiology, German Cancer Research Center, Heidelberg, Germany
    Cancer 103:740-8. 2005
    ..However, only a minority of HBV carriers eventually develop hepatocellular carcinoma. The authors hypothesized that cytokine genotypes may be important codeterminants of the risk of HBV-related hepatocellular carcinoma...
  79. ncbi request reprint Association between circulating white blood cell count and cancer mortality: a population-based cohort study
    Anoop Shankar
    Division of Epidemiology, Department of Community, Occupational, and Family Medicine and the Centre for Molecular Epidemiology, National University of Singapore, Singapore
    Arch Intern Med 166:188-94. 2006
    ..However, it is not clear whether systemic markers of inflammation predict cancer. We examined the prospective relationship between circulating white blood cell (WBC) count and cancer mortality...
  80. ncbi request reprint Effects of cruciferous vegetable consumption on urinary metabolites of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in singapore chinese
    Stephen S Hecht
    University of Minnesota Cancer Center, Mayo Mail Code 806, 420 Delaware St SE, Minneapolis, MN 55455, USA
    Cancer Epidemiol Biomarkers Prev 13:997-1004. 2004
    ..The results of this study demonstrate the complexities in assessing effects of cruciferous vegetables on carcinogen metabolism...
  81. ncbi request reprint Peroxisome proliferator-activated receptor (PPAR) gamma gene polymorphisms and colorectal cancer risk among Chinese in Singapore
    Woon Puay Koh
    Department of Community, Occupational and Family Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Carcinogenesis 27:1797-802. 2006
    ..72 (0.49-1.07) among subjects possessing one low-risk genotype (either PPARgamma2 or PPARgamma3), and the comparable figure among subjects possessing both low-risk genotypes was 0.19 (0.07-0.51)...
  82. ncbi request reprint Determinants of circulating insulin-like growth factor I and insulin-like growth factor binding protein 3 concentrations in a cohort of Singapore men and women
    Nicole M Probst-Hensch
    University Hospital Zurich, Cancer Registry Zürich, Zurich, Switzerland
    Cancer Epidemiol Biomarkers Prev 12:739-46. 2003
    ..The results of this study lend additional support to the hypothesis that circulating IGF-I concentrations increase the risk of prostate, bladder, colorectal, and breast cancer...
  83. pmc Genetic polymorphisms in the methylenetetrahydrofolate reductase and thymidylate synthase genes and risk of hepatocellular carcinoma
    Jian Min Yuan
    The Cancer Center, University of Minnesota, Minneapolis, Minnesota 55454, USA
    Hepatology 46:749-58. 2007
    ..003). Individuals possessing the maximum number of mutant alleles (i.e., 4) had an odds ratio of 0.46 (95% confidence interval = 0.23-0.93) for HCC compared with those with no or only 1 mutant allele...
  84. ncbi request reprint Association of metabolic gene polymorphisms with tobacco consumption in healthy controls
    Kim M Smits
    University Maastricht, Maastricht, The Netherlands
    Int J Cancer 110:266-70. 2004
    ..No association between polymorphisms in the genes studied and tobacco consumption was observed; therefore, no effect of these genes on smoking behavior should be expected...
  85. ncbi request reprint Dietary fiber and reduced cough with phlegm: a cohort study in Singapore
    Lesley M Butler
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA
    Am J Respir Crit Care Med 170:279-87. 2004
    ..These data suggest that a diet high in fiber from fruit and, possibly, soyfoods may reduce the incidence of chronic respiratory symptoms. Associated nutrients, such as flavonoids, may contribute to this association...
  86. ncbi request reprint The effect of the cyclin D1 (CCND1) A870G polymorphism on colorectal cancer risk is modified by glutathione-S-transferase polymorphisms and isothiocyanate intake in the Singapore Chinese Health Study
    Nicole M Probst-Hensch
    Molecular Epidemiology Cancer Registry, Institutes of Social and Preventive Medicine Surgical Pathology, University Hospital Zurich Zurich, Switzerland
    Carcinogenesis 27:2475-82. 2006
    ..The results of our current study on CRC and those of our previous breast cancer study are compatible with the notion of oxidative stress in target cells as important determinant of direction and magnitude of the CCND1 effect...
  87. pmc Vapor, dust, and smoke exposure in relation to adult-onset asthma and chronic respiratory symptoms: the Singapore Chinese Health Study
    Tricia D LeVan
    Arizona Respiratory Center, University of Arizona, Tucson, AZ, USA
    Am J Epidemiol 163:1118-28. 2006
    ..These data support the role of occupational exposures in the etiology of respiratory illness in a population-based cohort in Singapore with a low prevalence of atopic illness...
  88. ncbi request reprint Dietary factors and cancers of the renal pelvis and ureter
    Kaye E Brock
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Executive Plaza South, Room 8024, 6120 Executive Boulevard, MSC 7244, Bethesda, MD 20892 7244, USA
    Cancer Epidemiol Biomarkers Prev 15:1051-3. 2006
  89. ncbi request reprint Prediagnostic level of serum retinol in relation to reduced risk of hepatocellular carcinoma
    Jian Min Yuan
    The Cancer Center, University of Minnesota, Minneapolis, MN, USA
    J Natl Cancer Inst 98:482-90. 2006
    ....
  90. ncbi request reprint Increased hepatocarcinogenic potential of hepatitis B virus genotype A in Bantu-speaking sub-saharan Africans
    Michael C Kew
    MRC CANSA University Molecular Hepatology Research Unit, Department of Medicine, Medical School, University of the Witwatersrand, 7 York Road, Parktown 2193, Johannesburg, South Africa
    J Med Virol 75:513-21. 2005
    ..Genotype A has a greater hepatocarcinogenic potential than non-A genotypes in Bantu-speaking sub-saharan Africans and this is entirely attributable to subgenotype A1...