Samuel A Yousem

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint The pulmonary histopathologic manifestations of the anti-PL7/antithreonyl transfer RNA synthetase syndrome
    Samuel A Yousem
    Departments of Pathology, Rheumatology, and Pulmonary Medicine, UPMC Presbyterian, Pittsburgh, PA 15213 2582 Electronic address
    Hum Pathol 45:1199-204. 2014
  2. doi request reprint Immunohistochemical and molecular characterization of clear cell carcinoma of the lung
    Samuel A Yousem
    UPMC Presbyterian A610, Department of Pathology, Pittsburgh, PA 15213 2582 Electronic address
    Hum Pathol 44:2467-74. 2013
  3. doi request reprint HepPar-1 expression in primary lung adenocarcinoma
    Samuel A Yousem
    Department of Pathology, UPMC Presbyterian Shadyside, Presbyterian Campus A610, 200 Lothrop St, Pittsburgh, PA 15213 2582, USA
    Am J Clin Pathol 140:225-30. 2013
  4. doi request reprint Pulmonary Langerhans cell histiocytosis: profiling of multifocal tumors using next-generation sequencing identifies concordant occurrence of BRAF V600E mutations
    Samuel A Yousem
    Department of Pathology, UPMC Presbyterian, Pittsburgh, PA 15213, USA
    Chest 143:1679-84. 2013
  5. doi request reprint The histopathology of lung allograft dysfunction associated with the development of donor-specific HLA alloantibodies
    Samuel A Yousem
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213 2582, USA
    Am J Surg Pathol 36:987-92. 2012
  6. doi request reprint Role of molecular studies in the diagnosis of lung adenocarcinoma
    Samuel A Yousem
    Department of Pathology, University of Pittsburgh Medical Center Presbyterian Campus, Pittsburgh, PA 15213 2582, USA
    Mod Pathol 25:S11-7. 2012
  7. ncbi request reprint Respiratory bronchiolitis-associated interstitial lung disease with fibrosis is a lesion distinct from fibrotic nonspecific interstitial pneumonia: a proposal
    Samuel A Yousem
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2582, USA
    Mod Pathol 19:1474-9. 2006
  8. ncbi request reprint Pulmonary intestinal-type adenocarcinoma does not show enteric differentiation by immunohistochemical study
    Samuel A Yousem
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 2582, USA
    Mod Pathol 18:816-21. 2005
  9. ncbi request reprint Recommendations for the supervision of pathology assistants: association of directors of anatomic and surgical pathology
    Samuel A Yousem
    University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Hum Pathol 37:253-5. 2006
  10. doi request reprint The histopathology of BRAF-V600E-mutated lung adenocarcinoma
    Samuel A Yousem
    Department of Pathology, Presbyterian Campus, UPMC Presbyterian Shadyside, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 32:1317-21. 2008

Detail Information

Publications61

  1. ncbi request reprint The pulmonary histopathologic manifestations of the anti-PL7/antithreonyl transfer RNA synthetase syndrome
    Samuel A Yousem
    Departments of Pathology, Rheumatology, and Pulmonary Medicine, UPMC Presbyterian, Pittsburgh, PA 15213 2582 Electronic address
    Hum Pathol 45:1199-204. 2014
    ....
  2. doi request reprint Immunohistochemical and molecular characterization of clear cell carcinoma of the lung
    Samuel A Yousem
    UPMC Presbyterian A610, Department of Pathology, Pittsburgh, PA 15213 2582 Electronic address
    Hum Pathol 44:2467-74. 2013
    ....
  3. doi request reprint HepPar-1 expression in primary lung adenocarcinoma
    Samuel A Yousem
    Department of Pathology, UPMC Presbyterian Shadyside, Presbyterian Campus A610, 200 Lothrop St, Pittsburgh, PA 15213 2582, USA
    Am J Clin Pathol 140:225-30. 2013
    ..To study a subset of lung adenocarcinomas with aberrant HepPar-1 antigen expression...
  4. doi request reprint Pulmonary Langerhans cell histiocytosis: profiling of multifocal tumors using next-generation sequencing identifies concordant occurrence of BRAF V600E mutations
    Samuel A Yousem
    Department of Pathology, UPMC Presbyterian, Pittsburgh, PA 15213, USA
    Chest 143:1679-84. 2013
    ..The molecular basis for this proliferation is unknown...
  5. doi request reprint The histopathology of lung allograft dysfunction associated with the development of donor-specific HLA alloantibodies
    Samuel A Yousem
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213 2582, USA
    Am J Surg Pathol 36:987-92. 2012
    ....
  6. doi request reprint Role of molecular studies in the diagnosis of lung adenocarcinoma
    Samuel A Yousem
    Department of Pathology, University of Pittsburgh Medical Center Presbyterian Campus, Pittsburgh, PA 15213 2582, USA
    Mod Pathol 25:S11-7. 2012
    ..Interestingly, these molecular changes have correlated with distinct, although not unique, demographics, histopathologies, and response to pharmacological agents...
  7. ncbi request reprint Respiratory bronchiolitis-associated interstitial lung disease with fibrosis is a lesion distinct from fibrotic nonspecific interstitial pneumonia: a proposal
    Samuel A Yousem
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2582, USA
    Mod Pathol 19:1474-9. 2006
    ..The morphology of this process raises the differential diagnosis with the fibrotic form of nonspecific interstitial pneumonia and highlights the role of cigarette smoking as a potential cause of fibrotic lung disease...
  8. ncbi request reprint Pulmonary intestinal-type adenocarcinoma does not show enteric differentiation by immunohistochemical study
    Samuel A Yousem
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213 2582, USA
    Mod Pathol 18:816-21. 2005
    ..Stains for a variety of epithelial mucins (MUC1, MUC2, MUC5AC) also support this observation. The differential diagnosis with other pulmonary adenocarcinomas, especially those with mucinous differentiation, is discussed...
  9. ncbi request reprint Recommendations for the supervision of pathology assistants: association of directors of anatomic and surgical pathology
    Samuel A Yousem
    University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Hum Pathol 37:253-5. 2006
  10. doi request reprint The histopathology of BRAF-V600E-mutated lung adenocarcinoma
    Samuel A Yousem
    Department of Pathology, Presbyterian Campus, UPMC Presbyterian Shadyside, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 32:1317-21. 2008
    ..Adenocarcinomas with this clinicopathologic phenotype may be worthwhile investigating for BRAF-V600E mutation as more genetically oriented drug therapies emerge...
  11. ncbi request reprint Pulmonary lymphohistiocytic reactions temporally related to etanercept therapy
    Samuel A Yousem
    The Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213 2582, USA
    Mod Pathol 18:651-5. 2005
    ..The association with etanercept therapy and granulomatous reactions is discussed along with the differential diagnosis...
  12. doi request reprint Peripheral squamous cell carcinoma of lung: patterns of growth with particular focus on airspace filling
    Samuel A Yousem
    Department of Pathology, University of Pittsburgh Medical Center, PA 15213 2582, USA
    Hum Pathol 40:861-7. 2009
    ..Nonetheless, such a growth pattern was common and should be studied further in larger series to determine if an airspace filling growth pattern in squamous carcinoma is clinically important...
  13. doi request reprint The pulmonary histopathologic manifestations of the anti-Jo-1 tRNA synthetase syndrome
    Samuel A Yousem
    Department of Pathology, UPMC Presbyterian Shadyside, Pittsburgh, PA 15213 2582, USA
    Mod Pathol 23:874-80. 2010
    ....
  14. doi request reprint The surgical pathology of pulmonary infarcts: diagnostic confusion with granulomatous disease, vasculitis, and neoplasia
    Samuel A Yousem
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2582, USA
    Mod Pathol 22:679-85. 2009
    ....
  15. doi request reprint Histopathology of aspiration pneumonia not associated with food or other particulate matter: a clinicopathologic study of 10 cases diagnosed on biopsy
    Samuel A Yousem
    Department of Pathology, University of Pittsburgh Medical Center, PA 15213 2582, USA
    Am J Surg Pathol 35:426-31. 2011
    ....
  16. ncbi request reprint HLA-specific antibodies are risk factors for lymphocytic bronchiolitis and chronic lung allograft dysfunction
    Alin L Girnita
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Transplant 5:131-8. 2005
    ....
  17. ncbi request reprint Widespread molecular alterations present in stage I non-small cell lung carcinoma fail to predict tumor recurrence
    Fabien K Baksh
    Department of Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, Pennsylvania 15213, USA
    Mod Pathol 16:28-34. 2003
    ..The approach of investigating a panel of genes for alterations can be applied to any given tumor type, and provides information on patterns of mutations/LOH that can help us better understand the molecular biology of tumorigenesis...
  18. ncbi request reprint Comparative mutational analysis of pulmonary scar epithelium, bronchioloalveolar carcinomas, and invasive well-differentiated pulmonary adenocarcinomas: a molecular approach to diagnostically challenging cases
    Hina A Sheikh
    Department of Pathology, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 29:1267-73. 2005
    ..These molecular differences may serve as an adjunct to histology in challenging glandular lesions of the lung...
  19. ncbi request reprint Comparison of mutational changes in involved N1 lymph nodes with those in primary tumors in stage II non-small cell lung cancer: a pilot study
    Hiran C Fernando
    Division of Thoracic and Foregut Surgery, University of Pittsburgh Medical Center Health System, UPMC Presbyterian, PA 15213, USA
    J Thorac Cardiovasc Surg 127:87-91. 2004
    ..This study compared mutational changes in involved lymph nodes and primary tumors from patients with stage II non-small cell lung cancer to determine whether risk factors for recurrence could be identified...
  20. ncbi request reprint Genetic profile of cumulative mutational damage associated with early pulmonary adenocarcinoma: bronchioloalveolar carcinoma vs. stage I invasive adenocarcinoma
    Eizaburo Sasatomi
    Departments of Pathology, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 28:1280-8. 2004
    ..LOH of 1p, 3p, 7q, and 18q was associated with invasive properties of pulmonary AD and may be useful in identifying invasive adenocarcinoma when conventional histomorphological tools are not helpful...
  21. ncbi request reprint A randomized trial of inhaled cyclosporine in lung-transplant recipients
    Aldo T Iacono
    Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, USA
    N Engl J Med 354:141-50. 2006
    ..Topical delivery of cyclosporine in addition to conventional systemic immunosuppression might help prevent acute and chronic rejection events...
  22. doi request reprint Micropapillary lung adenocarcinoma: EGFR, K-ras, and BRAF mutational profile
    Rosane De Oliveira Duarte Achcar
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2582, USA
    Am J Clin Pathol 131:694-700. 2009
    ..We conclude that K-ras, EGFR, and BRAF mutations are disproportionately seen in adenocarcinomas of lung with a dominant micropapillary growth pattern compared with conventional adenocarcinoma in our institutional experience...
  23. doi request reprint Anti-human leukocyte antigen antibodies, vascular C4d deposition and increased soluble c4d in broncho-alveolar lavage of lung allografts
    Alin L Girnita
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Transplantation 86:342-7. 2008
    ..A simultaneous determination of vascular C4d with soluble C4d in broncho-alveolar lavage fluid (BAL) and circulating anti-human leukocyte antigen (HLA) antibodies (HLA-Ab) has not been reported in lung transplantation...
  24. ncbi request reprint Loss of heterozygosity patterns of sclerosing hemangioma of the lung and bronchioloalveolar carcinoma indicate a similar molecular pathogenesis
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, PA 15213, USA
    Arch Pathol Lab Med 128:880-4. 2004
    ..Most cases of SH are benign, but they can metastasize to the regional lymph nodes...
  25. ncbi request reprint Significance of EGFR protein expression and gene amplification in non-small cell lung carcinoma
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, PA 15213, USA
    Am J Clin Pathol 125:860-5. 2006
    ..EGFR protein expression was uncoupled from gene amplification in most cases, although good correlation occurred in a subset of SCCs...
  26. doi request reprint Adenosquamous carcinoma of the lung: a microdissection study of KRAS and EGFR mutational and amplification status in a western patient population
    Naobumi Tochigi
    Dept of Pathology, UPMC Presbyterian Shadyside, Pittsburgh, PA 15213 2582, USA
    Am J Clin Pathol 135:783-9. 2011
    ..EGFR mutations occur in adenosquamous carcinoma in the same percentages as in conventional adenocarcinoma in the Western population. KRAS mutations are less common...
  27. doi request reprint Increased levels of tumor-infiltrating lymphocytes are associated with improved recurrence-free survival in stage 1A non-small-cell lung cancer
    Zachary D Horne
    Division of Thoracic Surgery, Heart, Lung, and Esophageal Surgery Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15232, USA
    J Surg Res 171:1-5. 2011
    ..We compared the outcomes of stage 1A NSCLC with and without tumor infiltrating lymphocytes to evaluate the effects of TILs on recurrence and survival patterns...
  28. ncbi request reprint Clonal selection of adenocarcinoma of the lung as determined by loss of heterozygosity
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, 200 Lothrop Street, PUH A610 2, Pittsburgh, PA 15213, USA
    Exp Mol Pathol 78:135-9. 2005
    ..A trend towards lower overall FAL in advanced stage tumors and in their metastases suggests that clonal selection may play a role in lung adenocarcinoma progression...
  29. doi request reprint Initial experience with a novel pre-sign-out quality assurance tool for review of random surgical pathology diagnoses in a subspecialty-based university practice
    Scott R Owens
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 34:1319-23. 2010
    ..The tool is a useful quality assurance instrument and its prospective nature allows for the potential prevention of some serious errors...
  30. doi request reprint Mammalian mastermind like 2 11q21 gene rearrangement in bronchopulmonary mucoepidermoid carcinoma
    Rosane de Oliveira Duarte Achcar
    Department of Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, PA 15213, USA
    Hum Pathol 40:854-60. 2009
    ....
  31. ncbi request reprint Pulmonary meningothelial-like nodules: a genotypic comparison with meningiomas
    Diana N Ionescu
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Room A610, 200 Lothrop St, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 28:207-14. 2004
    ..Minute pulmonary meningothelial-like nodules (MPMNs) are incidental interstitial pulmonary nodules. They share histologic, ultrastructural, and immunohistochemical features with meningiomas (MGs)...
  32. ncbi request reprint Recommendations for the supervision of pathology assistants
    Samuel A Yousem
    Department of Pathology, Presbyterian University Hospital A610, Pittsburgh, PA 15213 2582, USA
    Am J Surg Pathol 30:537-8. 2006
  33. ncbi request reprint Small-cell neuroendocrine carcinoma displays unique profiles of tumor-suppressor gene loss in relationship to the primary site of formation
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, PA 15213, USA
    Hum Pathol 33:927-32. 2002
    ..These attributes can be effectively used for primary localization of metastatic SCNC, thereby assisting in the diagnosis and classification of this neoplasm...
  34. pmc Inhibition and role of let-7d in idiopathic pulmonary fibrosis
    Kusum V Pandit
    University of Pittsburgh Medical Center, NW 628 MUH, 3459 5th Avenue, Pittsburgh, PA 15261, USA
    Am J Respir Crit Care Med 182:220-9. 2010
    ..Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and usually lethal fibrotic lung disease characterized by profound changes in epithelial cell phenotype and fibroblast proliferation...
  35. doi request reprint Gross cystic disease fluid protein-(GCDFP-15): expression in primary lung adenocarcinoma
    Joan M Striebel
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2582, USA
    Am J Surg Pathol 32:426-32. 2008
    ..This report details the first 11 cases of pulmonary adenocarcinoma to express GCDFP-15 and their distinctive morphology with frequent mucin production and coexpression of thyroid transcription factor-1 and synaptophysin...
  36. pmc A combination of molecular markers accurately detects lymph node metastasis in non-small cell lung cancer patients
    Liqiang Xi
    Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Clin Cancer Res 12:2484-91. 2006
    ..The combination of these genes identified 32 of 462 (7%) lymph nodes from 20 of 68 (29%) patients as potentially positive for occult metastasis. Long-term follow-up will determine the clinical relevance of these findings...
  37. ncbi request reprint Comparison of accumulated allele loss between primary tumor and lymph node metastasis in stage II non-small cell lung carcinoma: implications for the timing of lymph node metastasis and prognostic value
    Eizaburo Sasatomi
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15261, USA
    Cancer Res 62:2681-9. 2002
    ..552). A composite mutational profile for each patient based on the allelotyping of the primary tumor and lymph node deposits may make a significant contribution to a more accurate prognosis of stage II NSCLC...
  38. ncbi request reprint Microsatellite instability is uncommon in lymphoepithelioma-like carcinoma of the lung
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, PA 15213, USA
    Am J Clin Pathol 127:282-6. 2007
    ..55). MSI is very uncommon in LELC, indicating that MSI is not an important event in carcinogenesis for this tumor subtype. The presence of LOH suggests a probable role of tumor suppressor genes in LELC carcinogenesis...
  39. ncbi request reprint Patterns of allelic loss of synchronous adenocarcinomas of the lung
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, PA 15213, USA
    Am J Surg Pathol 29:897-902. 2005
    ..Our study showed that discordant and concordant genotypic profiles exist in morphologically similar synchronous ADC of the lung...
  40. ncbi request reprint Significance of a solitary perivascular mononuclear infiltrate in lung allograft recipients with mild acute cellular rejection
    Dong Won Kim
    Department of Pathology and Pulmonary Medicine, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, PA 15213, USA
    J Heart Lung Transplant 24:152-5. 2005
    ..We evaluated the significance of a solitary perivascular mononuclear infiltrate and its correlation with clinical outcome in lung allograft recipients...
  41. doi request reprint Impact of angiolymphatic and pleural invasion on surgical outcomes for stage I non-small cell lung cancer
    Matthew J Schuchert
    Division of Thoracic and Foregut Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Ann Thorac Surg 91:1059-65; discussion 1065. 2011
    ..In the current study, we analyze the impact of pathologic variables (angiolymphatic invasion, visceral pleural invasion, and tumor inflammation) upon survival outcomes after segmentectomy or lobectomy for stage I non-small cell lung cancer...
  42. doi request reprint Nonspecific interstitial pneumonia: a study of 6 patients with progressive disease
    Frank Schneider
    Department of Pathology and Pulmonary Medicine, University of Pittsburgh Medical Center Presbyterian, Pittsburgh, PA, USA
    Am J Surg Pathol 36:89-93. 2012
    ..The potential pathophysiologic explanation for such a change is discussed...
  43. doi request reprint Frozen section diagnosis: is there discordance between what pathologists say and what surgeons hear?
    Somak Roy
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Am J Clin Pathol 140:363-9. 2013
    ..The frozen section (FS) diagnosis in patient care is dependent on successful communication between pathologists and surgeons. However, very few studies looking at FS errors analyzed postanalytic communication issues...
  44. ncbi request reprint HLA-specific antibodies are associated with high-grade and persistent-recurrent lung allograft acute rejection
    Alin L Girnita
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15261, USA
    J Heart Lung Transplant 23:1135-41. 2004
    ..The impact of HLA-specific antibodies is not well established in the acute rejection of lung allografts. Acute rejection represents the most important risk factor for the development of chronic lung allograft dysfunction...
  45. doi request reprint Asthmatic granulomatosis: a novel disease with asthmatic and granulomatous features
    Sally E Wenzel
    University of Pittsburgh Asthma Institute at University of Pittsburgh Medical Center University of Pittsburgh School of Medicine, Pulmonary Allergy and Critical Care Medicine Division, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Am J Respir Crit Care Med 186:501-7. 2012
    ..Although it is increasingly recognized as consisting of numerous heterogenous phenotypes, their immunopathology, particularly in the distal airways and interstitium, remains poorly described...
  46. pmc Impact of mold infections in explanted lungs on outcomes of lung transplantation
    Aniket Vadnerkar
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15251, USA
    Transplantation 89:253-60. 2010
    ..Little is known about the incidence or significance of mold infections in the explanted lungs of lung transplant recipients...
  47. ncbi request reprint Recurrent sarcoidosis in lung transplant allografts: granulomas are of recipient origin
    Diana N Ionescu
    Department of Pathology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Diagn Mol Pathol 14:140-5. 2005
    ..The origin of the histiocytes composing the noncaseating granulomas in the allograft lung in patients with recurrent sarcoidosis (RS) was analyzed using DNA identity testing in 4 cases...
  48. doi request reprint Numerical fidelity of endoscopic biopsy fragments in the processing sequence of a university surgical pathology laboratory
    Scott R Owens
    Department of Pathology, University of Pittsburgh Medical Center, Presbyterian Campus, Pennsylvania 15213 2582, USA
    Arch Pathol Lab Med 135:1561-4. 2011
    ..Conservation and effective utilization of small biopsy tissue is therefore crucial in the pathology laboratory...
  49. ncbi request reprint Histologic classification of idiopathic chronic interstitial pneumonias
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, Pennsylvania, USA
    Am J Respir Cell Mol Biol 29:S5-9. 2003
  50. pmc Gene expression profiles of acute exacerbations of idiopathic pulmonary fibrosis
    Kazuhisa Konishi
    Division of Pulmonary, Allergy and Critical Care Medicine, Dorothy P and Richard P Simmons Center for Interstitial Lung Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Am J Respir Crit Care Med 180:167-75. 2009
    ..The molecular mechanisms underlying acute exacerbations of idiopathic pulmonary fibrosis (IPF) are poorly understood. We studied the global gene expression signature of acute exacerbations of IPF...
  51. ncbi request reprint Idiopathic bronchiolocentric interstitial pneumonia
    Samuel A Yousem
    Department of Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, Pennsylvania 15213, USA
    Mod Pathol 15:1148-53. 2002
    ....
  52. pmc Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease
    Zhi Hua Chen
    Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    PLoS ONE 3:e3316. 2008
    ..Autophagy is a degradative process involving lysosomal turnover of cellular components, though its role in human diseases remains unclear...
  53. ncbi request reprint Bronchioloalveolar carcinoma: a review of current concepts and evolving issues
    Samuel A Yousem
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Arch Pathol Lab Med 131:1027-32. 2007
    ..Both pathologic and clinical aspects of this carcinoma are the subject of considerable interest...
  54. doi request reprint Tissue adequacy for ancillary studies beyond frozen section: a potential method for improving diagnostic and therapeutic results
    Douglas J Hartman
    1University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Int J Surg Pathol 21:583-6. 2013
    ..We have instituted a new assessment for intraoperative consultations to optimize the tissue obtained and reduce the need for additional procedures. ..
  55. doi request reprint The development and testing of a laboratory information system-driven tool for pre-sign-out quality assurance of random surgical pathology reports
    Scott R Owens
    Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Am J Clin Pathol 133:836-41. 2010
    ..There has been no significant delay in case turnaround time since implementation. Further assessment of the tool's function after full departmental application is underway...
  56. ncbi request reprint Epstein-Barr virus infection is not associated with fibroadenomas of the breast in immunosuppressed patients after organ transplantation
    Sean K Lau
    Department of Pathology, City of Hope National Medical Center, Duarte, California 91010, USA
    Mod Pathol 16:1242-7. 2003
    ..The findings of the present study argue against a significant relationship between Epstein-Barr virus and fibroadenomas of the breast in the setting of transplant-associated immunosuppression...
  57. ncbi request reprint Molecular pathogenesis of pulmonary carcinosarcoma as determined by microdissection-based allelotyping
    Sanja Dacic
    Department of Pathology, Division of Anatomic Pathology, University of Pittsburgh Medical Center, Presbyterian University Hospital, Pittsburgh, Pennsylvania, USA
    Am J Surg Pathol 26:510-6. 2002
    ..The data support the efficacy of microdissection-based allelic fingerprinting to delineate the relationship between different morphologic components of a single neoplasm...
  58. ncbi request reprint In vivo expression of p53 and Bcl-2 and their role in programmed cell death in premalignant and malignant lung lesions
    Patrick P Koty
    Department of Environmental and Occupational Health, University of Pittsburgh, 260 Kappa Drive, Pittsburgh, PA 15238, USA
    Lung Cancer 35:155-63. 2002
    ..The ensuing increase in apoptosis appears to be relatively independent of mutant or wild-type p53 expression, but does not occur in cells expressing bcl-2...
  59. ncbi request reprint Intrathymic inoculation of donor bone marrow induces long-term acceptance of lung allografts
    Sen Li
    Division of Cardiothoracic Surgery, University of Miami School of Medicine, Miami, Florida 33136, USA
    Ann Thorac Surg 75:257-63; discussion 263. 2003
    ..We investigated whether intrathymic inoculation of donor bone marrow at the time of transplantation induced long-term acceptance of lung allografts...
  60. ncbi request reprint Revision of the 1996 working formulation for the standardization of nomenclature in the diagnosis of lung rejection
    Susan Stewart
    Papworth Everard Pathology Department, Papworth Hospital, Cambridge, UK
    J Heart Lung Transplant 26:1229-42. 2007
    ..This consensus revision of the working formulation was approved by the ISHLT board of directors in April 2007...
  61. ncbi request reprint Recommendations for the supervision of pathology assistants
    Samuel A Yousem
    Am J Clin Pathol 125:171-2. 2006