Research Topics
| Eric YoungstromSummaryAffiliation: University of North Carolina Country: USA Publications
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Detail Information
Publications
The bipolar spectrum: myth or reality?Eric Youngstrom
Departments of Psychiatry and Psychology, University of North Carolina, Chapel Hill, 27599 3270, USA
Curr Psychiatry Rep 12:479-89. 2010..Practitioners can use inexpensive and practical strategies to incorporate the spectrum concept into their work while minimizing risks of overdiagnosis or unnecessary medication exposure...
Developing a 10-item mania scale from the Parent General Behavior Inventory for children and adolescentsEric A Youngstrom
Department of Psychology, University of North Carolina at Chapel Hill, NC 27599 3270, USA
J Clin Psychiatry 69:831-9. 2008..The goal of the present study was to develop and validate a brief (10 item) instrument to assess mania in a large sample of outpatients presenting with a variety of different DSM-IV diagnoses, including frequent comorbid conditions...
Comparing the effects of sampling designs on the diagnostic accuracy of eight promising screening algorithms for pediatric bipolar disorderEric Youngstrom
Department of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 3270, USA
Biol Psychiatry 60:1013-9. 2006..The present investigation compared eight screening algorithms in the same sample but under two different design strategies...
Advancing the selection of neurodevelopmental measures in epidemiological studies of environmental chemical exposure and health effectsEric Youngstrom
Departments of Psychology and Psychiatry, University of North Carolina at Chapel Hill, Davie Hall, CB 3270, University of North Carolina, Chapel Hill, NC 27599, USA
Int J Environ Res Public Health 7:229-68. 2010..We also discuss important considerations in selecting appropriate tests and provide a case study by reviewing the literature on polychlorinated biphenyls...
Pediatric bipolar disorder: validity, phenomenology, and recommendations for diagnosisEric A Youngstrom
Department of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 3270, USA
Bipolar Disord 10:194-214. 2008..To find, review, and critically evaluate evidence pertaining to the phenomenology of pediatric bipolar disorder and its validity as a diagnosis...
Diagnostic and measurement issues in the assessment of pediatric bipolar disorder: implications for understanding mood disorder across the life cycleEric Youngstrom
Department of Psychology, University of North Carolina, Chapel Hill, NC 27599, USA
Dev Psychopathol 18:989-1021. 2006....
Comparing diagnostic checklists for pediatric bipolar disorder in academic and community mental health settingsEric Youngstrom
Department of Psychology, Case Western Reserve University, Cleveland, OH 44106, USA
Bipolar Disord 7:507-17. 2005....
A proposal to facilitate weight-of-evidence assessments: Harmonization of Neurodevelopmental Environmental Epidemiology Studies (HONEES)Eric Youngstrom
Departments of Psychology and Psychiatry, University of North Carolina at Chapel Hill Davie Hall, University of North Carolina, Chapel Hill, NC 27599, USA
Neurotoxicol Teratol 33:354-9. 2011..Broad acceptance and application of such an approach can facilitate the expanded use of environmental epidemiology studies of potential neurodevelopmental toxicants in the protection of public health, and specifically children's health...
The effects of including a callous-unemotional specifier for the diagnosis of conduct disorderRachel E Kahn
University of New Orleans, New Orleans, LA, USA
J Child Psychol Psychiatry 53:271-82. 2012..The impact of this specifier on children diagnosed with CD should be considered...
Discriminative validity of the general behavior inventory using youth reportCarla Kmett Danielson
Department of Psychology, Case Western Reserve University, Cleveland, Ohio 44106-7123, USA
J Abnorm Child Psychol 31:29-39. 2003....
Comparing the psychometric properties of multiple teacher report instruments as predictors of bipolar disorder in children and adolescentsEric A Youngstrom
Department of Psychology, University of North Carolina, Chapel Hill, NC 27599 3270, USA
J Clin Psychol 64:382-401. 2008..Teacher report appears to be insufficiently specific or sensitive to BPSD for clinical diagnostic use, although teacher scales might have research utility...
A quantitative and qualitative review of neurocognitive performance in pediatric bipolar disorderMegan F Joseph
Department of Psychology, University of North Carolina Chapel Hill, Chapel Hill, North Carolina 27599, USA
J Child Adolesc Psychopharmacol 18:595-605. 2008..Study reporting guidelines are offered that may help clarify the impact of illness definitions, mood state, medication status, and other methodological variables on neurocognition in pediatric BD...
Neurocognition in early-onset schizophrenia and schizoaffective disordersStephen R Hooper
The Carolina Institute for Developmental Disabilities, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7255, USA
J Am Acad Child Adolesc Psychiatry 49:52-60. 2010....
Who are the comorbid adolescents? Agreement between psychiatric diagnosis, youth, parent, and teacher reportEric A Youngstrom
Department of Psychology, Case Western Reserve University, Cleveland, Ohio 44106 7123, USA
J Abnorm Child Psychol 31:231-45. 2003..14-.40). Results also indicate that single DSM-IV disorders, such as bipolar disorder, can manifest "comorbid" patterns of behavior problems on checklists...
Quality of life in pediatric bipolar disorderAndrew J Freeman
University of North Carolina, Department of Psychology, CB3270, Davie Hall, Chapel Hill, NC 27599 3270, USA
Pediatrics 123:e446-52. 2009..The current study examines the quality of life in children and adolescents with bipolar disorder compared with other physical and psychiatric illnesses...
The assessment of children and adolescents with bipolar disorderEric A Youngstrom
Department of Psychology, University of North Carolina, Chapel Hill, NC 27599 3270, USA
Child Adolesc Psychiatr Clin N Am 18:353-90, viii-ix. 2009..By the end of the article, clinicians will have a framework and set of clinically useful tools with which to effectively make evidence-based decisions regarding the diagnosis of BPD in children and adolescents...
Bipolar diagnoses in community mental health: Achenbach Child Behavior Checklist profiles and patterns of comorbidityEric Youngstrom
Department of Psychology, Case Western Reserve University, Cleveland, Ohio 44106 7123, USA
Biol Psychiatry 58:569-75. 2005..However, no study has examined clinical or demographic characteristics of youths clinically diagnosed with bipolar disorder in a low-income, diverse community clinical sample...
Comparing the diagnostic accuracy of six potential screening instruments for bipolar disorder in youths aged 5 to 17 yearsEric A Youngstrom
Department of Psychology, Case Western Reserve University, University Hospitals of Cleveland, Ohia 44106 7123, USA
J Am Acad Child Adolesc Psychiatry 43:847-58. 2004..To compare the diagnostic efficiency of six index tests as predictors of juvenile bipolar disorder in two large outpatient samples, aged 5 to 10 and 11 to 17 years, gathered from 1997 to 2002...
Evidence-based assessment of attention-deficit/hyperactivity disorder: measuring outcomesSteven W Evans
Alvin V. Baird Attention and Learning Disabilities Center, Department of Psychology, James Madison University, Harrisonburg, VA 22807, USA
J Am Acad Child Adolesc Psychiatry 45:1132-7. 2006
Sex differences in pediatric bipolar disorderJeanne M Duax
Department of Psychology, Case Western Reserve University, Cleveland, OH 44106 7123, USA
J Clin Psychiatry 68:1565-73. 2007..To explore sex differences in pediatric bipolar disorder in terms of subtype and severity of depressive and manic symptomatology...
The role of family functioning in bipolar disorder in familiesTina D Du Rocher Schudlich
Department of Psychology, Western Washington University, 516 High Street, MS 9089, Bellingham, WA 98225 9089, USA
J Abnorm Child Psychol 36:849-63. 2008..Associations between parent diagnoses and family functioning changed depending on youth age, but not youth sex...
Meta-analysis of intellectual and neuropsychological test performance in attention-deficit/hyperactivity disorderThomas W Frazier
Department of Psychology, Case Western Reserve University, Cleveland, OH 44195, USA
Neuropsychology 18:543-55. 2004..These findings indicate that overall cognitive ability is significantly lower among persons with ADHD and that FSIQ may show as large a difference between ADHD and control participants as most other measures...
Evidence-based assessment of pediatric bipolar disorder, Part II: Incorporating information from behavior checklistsEric A Youngstrom
Department of Psychology, Case Western Reserve University, Cleveland, OH 44106, USA
J Am Acad Child Adolesc Psychiatry 44:823-8. 2005
Factor and subtest discrepancies on the differential ability scales: examining prevalence and validity in predicting academic achievementShoshana Y Kahana
Department of Psychology, Case Western Reserve University, Cleveland, OH 44106 7123, USA
Assessment 9:82-93. 2002..Findings suggest that when predicting academic achievement, there is little value in interpreting cognitive scores beyond the global ability estimate...
Clinical significance of treatment effects with aripiprazole versus placebo in a study of manic or mixed episodes associated with pediatric bipolar I disorderEric Youngstrom
Department of Psychology, University of North Carolina, Chapel Hill, North Carolina 27599, USA
J Child Adolesc Psychopharmacol 23:72-9. 2013..Published studies in adult and pediatric bipolar disorder have used different definitions of treatment response. This analysis aimed to compare different definitions of response in a large sample of children and adolescents...
Toward an evidence-based assessment of pediatric bipolar disorderEric A Youngstrom
Department of Psychology, Case Western Reserve University, Cleveland, OH 44106 7123, USA
J Clin Child Adolesc Psychol 34:433-48. 2005..Twelve recommendations are offered to move toward an evidence-based assessment model for PBD...
Behavioral inhibition system (BIS) strength and trait dominance are associated with affective response and perspective taking when viewing dyadic interactionsHeath A Demaree
Department of Psychology, Case Western Reserve University, Cleveland, Ohio 44106 7123, USA
Int J Neurosci 115:1579-93. 2005..Interestingly, although not hypothesized, trait dominance was also associated with character identification by virtue of being positively associated with BAS and PA and negatively associated with BIS and NA...
Evidence-based assessment of pediatric bipolar disorder, part I: base rate and family historyEric A Youngstrom
Department of Psychology, Case Western Reserve University, Cleveland, OH 44106-7123, USA
J Am Acad Child Adolesc Psychiatry 44:712-7. 2005
Increasing the reliability of ipsative interpretations in neuropsychology: a comparison of reliable components analysis and other factor analytic methodsThomas W Frazier
Department of Psychology, Case Western Reserve University, Cleveland, Ohio, USA
J Int Neuropsychol Soc 10:578-89. 2004..These findings suggest that difference scores derived from orthogonal factor solutions, particularly RCA solutions, may improve reliability for clinical assessment purposes...
Toward an integration of parent and clinician report on the Young Mania Rating ScaleEric A Youngstrom
Department of Psychiatry at Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH, USA
J Affect Disord 77:179-90. 2003..The Young Mania Rating Scale (YMRS) has validity in the assessment of mania in adults. The purpose of this study was to examine how the YMRS might optimally be used in the assessment of youths...
A Parent General Behavior Inventory subscale to measure sleep disturbance in pediatric bipolar disorderOren I Meyers
Mandel School of Applied Social Sciences, Case Western Reserve University, Cleveland, Ohio 44106 7123, USA
J Clin Psychiatry 69:840-3. 2008....
Consensus report on impulsive aggression as a symptom across diagnostic categories in child psychiatry: implications for medication studiesPeter S Jensen
Center for the Advancement of Children s Mental Health, Columbia University NYSPI 1051 Riverside Drive, Unit 78, New York, NY 10032, USA
J Am Acad Child Adolesc Psychiatry 46:309-22. 2007..If so, how should IA be assessed, pharmacological studies designed, and ethical issues addressed?..
Evaluation and comparison of psychometric instruments for pediatric bipolar spectrum disorders in four age groupsThomas W Frazier
Department of Psychiatry, University Hospitals Case Medical Center, Cleveland, OH, USA
J Child Adolesc Psychopharmacol 17:853-66. 2007..The CDRS-R may be better conceptualized as a two-factor measure in older adolescents. The semistructured K-SADS interview can be used to generate reliable diagnoses across a broad age range...
Clinical implications of pervasive manic symptoms in childrenGabrielle A Carlson
Department of Psychiatry, State University of New York at Stony Brook, Stony Brook, New York 11794, USA
Biol Psychiatry 53:1050-8. 2003..CONCLUSIONS: Youths for whom multiple informants report manic symptoms appear likely to have more severe symptom presentation and more complicated, refractory courses than do youths without manic symptoms...
Employing parent, teacher, and youth self-report checklists in identifying pediatric bipolar spectrum disorders: an examination of diagnostic accuracy and clinical utilityShoshana Y Kahana
Case Western Reserve University, Cleveland, Ohio 44106, USA
J Child Adolesc Psychopharmacol 13:471-88. 2003..Results indicate that the Child Behavior Checklist has limited utility when attempting to derive clinically meaningful information about the presentation of juvenile BPSD...
Diagnostic guidelines for bipolar disorder: a summary of the International Society for Bipolar Disorders Diagnostic Guidelines Task Force ReportS Nassir Ghaemi
Bipolar Disorder Research Program, Department of Psychiatry, Emory University, Atlanta, GA 30322, USA
Bipolar Disord 10:117-28. 2008....
Evidence-based assessment of attention-deficit/hyperactivity disorder: using multiple sources of informationThomas W Frazier
Department of Psychiatry and Psychology, Section of Neuropsychology, Cleveland Clinic Foundation, John Carroll University, OH 44118, USA
J Am Acad Child Adolesc Psychiatry 45:614-20. 2006
Factor structure of the Young Mania Rating Scale for use with youths ages 5 to 17 yearsEric A Youngstrom
Case Western Reserve University, University Hospitals of Cleveland, USA
J Clin Child Adolesc Psychol 31:567-72. 2002..However, the young male group showed higher scores on several items as well as the total YMRS score. Results suggest that the YMRS total score can be meaningfully interpreted in child and adolescent samples...
Review and meta-analysis of the phenomenology and clinical characteristics of mania in children and adolescentsRobert A Kowatch
Department of Psychiatry, Cincinnati Children s Hospital Medical Center University of Cincinnati Medical Center, Cincinnati, OH 45267, USA
Bipolar Disord 7:483-96. 2005....
Effects of adolescent manic symptoms on agreement between youth, parent, and teacher ratings of behavior problemsEric A Youngstrom
Department of Psychiatry, Case Western Reserve University CWRU and University Hospitals of Cleveland, Cleveland, OH 441106 7123, USA
J Affect Disord 82:S5-S16. 2004....
Early symptoms of mania and the role of parental riskRobert L Findling
Department of Psychiatry, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH 44106, USA
Bipolar Disord 7:623-34. 2005....
The child bipolar questionnaire: a dimensional approach to screening for pediatric bipolar disorderDemitri Papolos
The Juvenile Bipolar Research Foundation, USA
J Affect Disord 95:149-58. 2006..This report provides preliminary data on the reliability and validity of the CBQ...
Clinical decision-making using the General Behavior Inventory in juvenile bipolarityRobert L Findling
Department of Psychiatry, University Hospitals of Cleveland Case Western Reserve University School of Medicine, Cleveland, OH 44106 5080, USA
Bipolar Disord 4:34-42. 2002..The General Behavior Inventory (GBI) is a questionnaire that has utility in the assessment of mood disorders in adults. The purpose of this study was to examine how the GBI might optimally be used in the assessment of youths...
Elevated thyrotropin in bipolar youths prescribed both lithium and divalproex sodiumBarbara L Gracious
Strong Memorial Hospital, University of Rochester Medical Center, Rochester, NY 14642, USA
J Am Acad Child Adolesc Psychiatry 43:215-20. 2004..To examine the effect of combined lithium and divalproex sodium on thyroid-stimulating hormone (TSH) levels in children and adolescents with bipolar disorders and to identify risk factors for lithium-induced hypothyroidism...
Methodological issues and controversies in clinical trials with child and adolescent patients with bipolar disorder: report of a consensus conferenceGabrielle A Carlson
Department of Psychiatry, Stony Brook University Putnam Hall, Stony Brook, NY 11794 8790, USA
J Child Adolesc Psychopharmacol 13:13-27. 2003..To achieve consensus among researchers, pharmaceutical industry representatives, federal regulatory agency staff, and family advocates on a template for clinical trials of acute mania/bipolar disorder in children and adolescents...
Discriminative validity of a parent version of the Young Mania Rating ScaleBarbara L Gracious
Case Western Reserve University, Cleveland, OH, USA
J Am Acad Child Adolesc Psychiatry 41:1350-9. 2002..To examine the usefulness of a parent report version of the Young Mania Rating Scale (P-YMRS) in distinguishing bipolar disorder from other mental health conditions in children and adolescents...
A prospective, open-label trial of olanzapine in adolescents with schizophreniaRobert L Findling
Department of Psychiatry, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, OH 44106, USA
J Am Acad Child Adolesc Psychiatry 42:170-5. 2003..Olanzapine is an atypical antipsychotic that has efficacy in adults with psychotic disorders. This preliminary study examined the effectiveness of olanzapine in adolescents with schizophrenia or its related conditions...
Combination lithium and divalproex sodium in pediatric bipolarityRobert L Findling
Department of Psychiatry, Case Western Reserve University School of Medicine, USA
J Am Acad Child Adolesc Psychiatry 42:895-901. 2003..Many youths with bipolar disorder do not respond to DVPX or Li monotherapy. An open-label study was conducted to examine the effectiveness of combination DVPX and Li therapy with youths diagnosed with bipolar disorder...
A 20-month, double-blind, maintenance trial of lithium versus divalproex in rapid-cycling bipolar disorderJoseph R Calabrese
Case Western Reserve University, University Hospitals of Cleveland, Cleveland, OH 44106, USA
Am J Psychiatry 162:2152-61. 2005..The authors tested the hypothesis that divalproex would be more effective than lithium in the long-term management of patients with recently stabilized rapid-cycling bipolar disorder...
Treatment adherence in individuals with rapid cycling bipolar disorder: results from a clinical-trial settingMartha Sajatovic
J Clin Psychopharmacol 27:412-4. 2007
Double-blind 18-month trial of lithium versus divalproex maintenance treatment in pediatric bipolar disorderRobert L Findling
Department of Psychiatry, Case Western Reserve University, USA
J Am Acad Child Adolesc Psychiatry 44:409-17. 2005....
Combination lithium and divalproex sodium in pediatric bipolar symptom re-stabilizationRobert L Findling
Department of Psychiatry, Case Western Reserve University, University Hospitals, Cleveland, OH 44106, USA
J Am Acad Child Adolesc Psychiatry 45:142-8. 2006..The primary goal of this study was to assess the rate of re-stabilization after the resumption of lithium (Li) plus divalproex (DVPX) following relapse on either agent as monotherapy...
ADHD and college students: exploratory and confirmatory factor structures with student and parent dataJoseph J Glutting
School of Education, University of Delaware, Newark, DE 19716 2922, USA
Psychol Assess 17:44-55. 2005..Factor structures replicated across genders (3 factors for the SRI, and 2 factors for the PRI). Results are discussed in terms of the divergence of structures...
Mood state at study entry as predictor of the polarity of relapse in bipolar disorderJoseph R Calabrese
Case University School of Medicine, University Hospitals of Cleveland, 11400 Euclid Avenue, Suite 200, Cleveland, OH 44106, USA
Biol Psychiatry 56:957-63. 2004..We conclude that putative mood stabilizers must be tested in recently manic and recently depressed patients to determine their spectrum of prophylactic efficacy...
Cognitive-behavioral therapy for bipolar disorders in adolescents: a pilot studyNorah C Feeny
Department of Psychiatry, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, OH 44106, USA
Bipolar Disord 8:508-15. 2006..To develop a cognitive behavioral intervention for adolescents with bipolar disorders, test its feasibility and preliminary efficacy...
Behavioral outcomes and evidence of psychopathology among very low birth weight infants at age 20 yearsMaureen Hack
Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA
Pediatrics 114:932-40. 2004..We thus sought to examine gender-specific behavioral outcomes and evidence of psychopathology in a cohort of VLBW young adults at 20 years of age...
Barriers to the identification and management of psychosocial issues in children and maternal depressionSarah McCue Horwitz
Department of Epidemiology and Biostatistics, Case Western Reserve University School of Medicine, Room W G 72, 10900 Euclid Ave, Cleveland, Ohio 44106 4945, USA
Pediatrics 119:e208-18. 2007..Child psychosocial issues and maternal depression are underidentified and undertreated, but we know surprisingly little about the barriers to identification and treatment of these problems by primary care pediatricians...
The latent structure of attention-deficit/hyperactivity disorder in a clinic-referred sampleThomas W Frazier
Department of Psychiatry and Psychology, Section of Neuropsychology, The Cleveland Clinic, Cleveland, OH 44195, USA
Neuropsychology 21:45-64. 2007..Alternatively, the null findings may have resulted from inadequate indicator selection. A dimensional model may better facilitate accurate identification of individuals at risk for functional impairment...
ADHD and achievement: meta-analysis of the child, adolescent, and adult literatures and a concomitant study with college studentsThomas W Frazier
Section of Behavioral Medicine, The Cleveland Clinic, Shaker Medical Campus, OH 44104, USA
J Learn Disabil 40:49-65. 2007..However, unlike earlier studies with children and adolescents, student ratings were as predictive as parent ratings. Findings are discussed in terms of the impact of moderator variables on ADHD and achievement...
The latent structure of cognitive symptom exaggeration on the Victoria Symptom Validity TestThomas W Frazier
Section of Behavioral Medicine, The Cleveland Clinic, Cleveland, OH 44104, USA
Arch Clin Neuropsychol 22:197-211. 2007..13-.14 in the present sample. Likelihood ratios are presented to assist clinical detection of individuals exhibiting the category of cognitive symptom exaggeration...
Response and remission in adolescent mania: signal detection analyses of the young mania rating scaleNick C Patel
Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0004, USA
J Am Acad Child Adolesc Psychiatry 46:628-35. 2007..The purpose of this study was to determine optimal criteria for defining response and remission in adolescents with acute mania...
Exploratory and confirmatory factor analysis of the autism diagnostic interview-revisedThomas W Frazier
Section of Behavioral Medicine, Children s Hospital for Rehabilitation, The Cleveland Clinic, Shaker Campus CR11, Cleveland, OH 44104, USA
J Autism Dev Disord 38:474-80. 2008..These findings indicate that the current ADI-R structure be revised to more accurately reflect the relationships between sub-scales...
Double-blind, placebo-controlled trial of divalproex monotherapy in the treatment of symptomatic youth at high risk for developing bipolar disorderRobert L Findling
Department of Psychiatry, Case Western Reserve University, and the University Hospitals of Cleveland, Cleveland, Ohio 44106 5080, USA
J Clin Psychiatry 68:781-8. 2007..To determine if divalproex sodium was superior to placebo in the treatment of symptomatic youths who suffer from a bipolar spectrum disorder and who also have a parent with a diagnosis of a bipolar illness...
