Carlton J Young

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. doi request reprint Are there still roles for exocrine bladder drainage and portal venous drainage for pancreatic allografts?
    Carlton J Young
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    Curr Opin Organ Transplant 14:90-4. 2009
  2. ncbi request reprint Health disparities in transplantation: focus on the complexity and challenge of renal transplantation in African Americans
    Carlton J Young
    Division of Transplantation, Department of Surgery, University of Alabama at Birmingham, Lyons Harrison Research Building, LHRB 728, Birmingham, AL 35294 0007, USA
    Med Clin North Am 89:1003-31, ix. 2005
  3. ncbi request reprint Suppression of the c-Jun N-terminal kinase pathway by 17beta-estradiol can preserve human islet functional mass from proinflammatory cytokine-induced destruction
    Devin E Eckhoff
    Division of Transplantation, and Transplant Center, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Surgery 134:169-79. 2003
  4. ncbi request reprint Brain death significantly reduces isolated pancreatic islet yields and functionality in vitro and in vivo after transplantation in rats
    Juan L Contreras
    Division of Transplantation, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Diabetes 52:2935-42. 2003
  5. ncbi request reprint Enhanced isolated pancreatic islet recovery and functionality in rats by 17beta-estradiol treatment of brain death donors
    Devin E Eckhoff
    Division of Transplantation and Transplant Center, Department of Surgery Prosthodontics and Biomaterials, University of Alabama School of Dentistry, Birmingham, AL, USA
    Surgery 136:336-45. 2004
  6. ncbi request reprint A novel approach to xenotransplantation combining surface engineering and genetic modification of isolated adult porcine islets
    Juan L Contreras
    Department of Surgery, Division of Human Gene Therapy and Gene Therapy Center, University of Alabama at Birmingham, USA
    Surgery 136:537-47. 2004
  7. ncbi request reprint Double genetic modification of adenovirus fiber with RGD polylysine motifs significantly enhances gene transfer to isolated human pancreatic islets
    Juan L Contreras
    Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Transplantation 76:252-61. 2003
  8. ncbi request reprint 17beta-Estradiol protects isolated human pancreatic islets against proinflammatory cytokine-induced cell death: molecular mechanisms and islet functionality
    Juan L Contreras
    Transplant Center, University of Alabama at Birmingham, Birmingham, AL, USA
    Transplantation 74:1252-9. 2002
  9. ncbi request reprint Peripheral mobilization of recipient bone marrow-derived endothelial progenitor cells enhances pancreatic islet revascularization and engraftment after intraportal transplantation
    Juan L Contreras
    Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35295, USA
    Surgery 134:390-8. 2003
  10. ncbi request reprint Coupling endoplasmic reticulum stress to cell death program in isolated human pancreatic islets: effects of gene transfer of Bcl-2
    Juan L Contreras
    Division of Transplantation, University of Alabama at Birmingham, 748 Lyons Harrison Research Building, 701 19th Street South, AL 35294, Birmingham, USA
    Transpl Int 16:537-42. 2003

Detail Information

Publications23

  1. doi request reprint Are there still roles for exocrine bladder drainage and portal venous drainage for pancreatic allografts?
    Carlton J Young
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    Curr Opin Organ Transplant 14:90-4. 2009
    ....
  2. ncbi request reprint Health disparities in transplantation: focus on the complexity and challenge of renal transplantation in African Americans
    Carlton J Young
    Division of Transplantation, Department of Surgery, University of Alabama at Birmingham, Lyons Harrison Research Building, LHRB 728, Birmingham, AL 35294 0007, USA
    Med Clin North Am 89:1003-31, ix. 2005
    ..Factors that predispose African Americans for ESRD, impede this ethnic group from timely transplantation, and negatively influence graft survival are examined. Possible solutions to these persistent problems are offered...
  3. ncbi request reprint Suppression of the c-Jun N-terminal kinase pathway by 17beta-estradiol can preserve human islet functional mass from proinflammatory cytokine-induced destruction
    Devin E Eckhoff
    Division of Transplantation, and Transplant Center, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Surgery 134:169-79. 2003
    ..Previous studies demonstrated that 17beta-estradiol modulates the activity of JNK; therefore we assessed the effects of 17beta-estradiol on JNK activation on islet survival and function after transplantation...
  4. ncbi request reprint Brain death significantly reduces isolated pancreatic islet yields and functionality in vitro and in vivo after transplantation in rats
    Juan L Contreras
    Division of Transplantation, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Diabetes 52:2935-42. 2003
    ..In conclusion, brain death significantly reduced islet yields and functionality. These observations may lead to strategies to reduce the effects of brain death on pancreatic islets and improve the results in clinical transplantation...
  5. ncbi request reprint Enhanced isolated pancreatic islet recovery and functionality in rats by 17beta-estradiol treatment of brain death donors
    Devin E Eckhoff
    Division of Transplantation and Transplant Center, Department of Surgery Prosthodontics and Biomaterials, University of Alabama School of Dentistry, Birmingham, AL, USA
    Surgery 136:336-45. 2004
    ..Furthermore, inhibition of PIC release has been demonstrated after E2 treatment. In the present study, we evaluated if E2 treatment to BD donors would improve pancreatic islet recovery and functionality...
  6. ncbi request reprint A novel approach to xenotransplantation combining surface engineering and genetic modification of isolated adult porcine islets
    Juan L Contreras
    Department of Surgery, Division of Human Gene Therapy and Gene Therapy Center, University of Alabama at Birmingham, USA
    Surgery 136:537-47. 2004
    ..In this study, we assessed survival and function of surface-engineered porcine islets genetically modified to overexpress Bcl-2...
  7. ncbi request reprint Double genetic modification of adenovirus fiber with RGD polylysine motifs significantly enhances gene transfer to isolated human pancreatic islets
    Juan L Contreras
    Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Transplantation 76:252-61. 2003
    ....
  8. ncbi request reprint 17beta-Estradiol protects isolated human pancreatic islets against proinflammatory cytokine-induced cell death: molecular mechanisms and islet functionality
    Juan L Contreras
    Transplant Center, University of Alabama at Birmingham, Birmingham, AL, USA
    Transplantation 74:1252-9. 2002
    ..In this study, we evaluated the effects of estradiol on isolated human pancreatic islet (IHPI) survival after exposure to PIC and analyzed potential mechanisms of action...
  9. ncbi request reprint Peripheral mobilization of recipient bone marrow-derived endothelial progenitor cells enhances pancreatic islet revascularization and engraftment after intraportal transplantation
    Juan L Contreras
    Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35295, USA
    Surgery 134:390-8. 2003
    ..Therefore, we investigated the therapeutic potential of angioblast mobilization for stimulation of islet revascularization and therefore engraftment after transplantation...
  10. ncbi request reprint Coupling endoplasmic reticulum stress to cell death program in isolated human pancreatic islets: effects of gene transfer of Bcl-2
    Juan L Contreras
    Division of Transplantation, University of Alabama at Birmingham, 748 Lyons Harrison Research Building, 701 19th Street South, AL 35294, Birmingham, USA
    Transpl Int 16:537-42. 2003
    ..We can conclude that the current studies highlight the importance of Bcl-2 as an anti-apoptotic protein, and shed new light on the mechanisms underlying its cytoprotective effects on pancreatic islets...
  11. pmc Outcomes of brachiocephalic fistulas, transposed brachiobasilic fistulas, and upper arm grafts
    Ivan D Maya
    Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL 35233, USA
    Clin J Am Soc Nephrol 4:86-92. 2009
    ..The aim of this study was to compare the outcomes of three upper arm access types: brachiocephalic fistulas, transposed brachiobasilic fistulas, and grafts...
  12. ncbi request reprint Racial disparities in renal allograft survival: a public health issue?
    Devin E Eckhoff
    Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35294 0007, USA
    J Am Coll Surg 204:894-902; discussion 902-3. 2007
    ..The purpose of this study was to examine both immunologic and nonimmunologic risk factors for allograft loss with a goal of defining targeted strategies to improve outcomes among African Americans...
  13. doi request reprint Is surgical salvage of arteriovenous grafts feasible after unsuccessful percutaneous mechanical thrombectomy?
    Ivan D Maya
    Division of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Semin Dial 21:174-7. 2008
    ..Surgical salvage of a thrombosed AV graft after an unsuccessful percutaneous intervention is rarely feasible. Most patients have a severe anatomic lesion that cannot be repaired, and require creation of a new vascular access...
  14. ncbi request reprint Retrograde stenting for obstruction of the renal transplant ureter
    Edward R Gerrard
    Division of Urology, University of Alabama, Birmingham, Alabama 35294 3411, USA
    Urology 66:256-60; discussion 260. 2005
    ..To present our experience with retrograde stent placement and stent exchange for transplant ureteral obstruction...
  15. ncbi request reprint Increased risk of infection associated with polyurethane dialysis grafts
    Ivan D Maya
    Division of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Semin Dial 20:616-20. 2007
    ..In patients with an access emergency, implantation of a polyurethane graft incurs a tradeoff between earlier cannulation and a higher risk of infection...
  16. ncbi request reprint Emerging antibody therapy in organ transplantation
    Mario Vilatoba
    Division of Transplantation, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA
    Curr Surg 62:553-62, quiz 562-3. 2005
  17. ncbi request reprint Arteriovenous access outcomes in haemodialysis patients with HIV infection
    Dana Mitchell
    Division of Nephrology, 728 Richard Arrington Blvd, Birmingham, AL 35233, USA
    Nephrol Dial Transplant 22:465-70. 2007
    ..Arteriovenous (AV) grafts in haemodialysis patients usually fail due to thrombosis or infection. There is limited information on whether graft outcomes in HIV-positive haemodialysis patients differ from those in HIV-negative controls...
  18. ncbi request reprint African Americans and renal transplantation: disproportionate need, limited access, and impaired outcomes
    Carlton J Young
    Department of Surgery, Division of Transplantation, University of Alabama at Birmingham, 35294 0006, USA
    Am J Med Sci 323:94-9. 2002
    ..This imbalance, coupled with AA disproportionately representing those with ESRD, has kept AA disadvantaged compared with other races, especially whites...
  19. pmc Medial fibrosis, vascular calcification, intimal hyperplasia, and arteriovenous fistula maturation
    Michael Allon
    Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL, USA
    Am J Kidney Dis 58:437-43. 2011
    ..The pathogenesis of AVF nonmaturation may be related to pre-existing vascular pathologic states: medial fibrosis or microcalcification may limit arterial dilation, and intimal hyperplasia may cause stenosis...
  20. ncbi request reprint Donor nephrectomy: A comparison of techniques and results of open, hand assisted and full laparoscopic nephrectomy
    Rizk El-Galley
    University of Alabama at Birmingham, 35294 3411, USA
    J Urol 171:40-3. 2004
    ..There have been some concerns about the function of kidney grafts harvested by laparoscopic procedures. We report our results of LAP...
  21. ncbi request reprint Simvastatin induces activation of the serine-threonine protein kinase AKT and increases survival of isolated human pancreatic islets
    Juan L Contreras
    Transplant Center, Division of Transplantation, University of Alabama at Birmingham, 748 Lyons Harrison Research Building, 701 19th Street South, Birmingham, AL 35294, USA
    Transplantation 74:1063-9. 2002
    ..Simvastatin activates Akt in mammalian cells; therefore, we investigated the role of simvastatin on human pancreatic islets (HPI) survival...
  22. ncbi request reprint Hemodialysis arteriovenous fistula maturity: US evaluation
    Michelle L Robbin
    Department of Radiology, University of Alabama at Birmingham, 619 19th St S, JTN350, Birmingham, AL 35249 6830, USA
    Radiology 225:59-64. 2002
    ..To compare various objective ultrasonographic (US) criteria for native arteriovenous fistula (AVF) maturation with subsequent fistula outcomes and clinical evaluation by experienced dialysis nurses...
  23. ncbi request reprint Understanding the influence of ethnicity on renal allograft survival
    Carlton J Young
    Am J Transplant 5:2603-4. 2005