Research Topics
Genomes and Genes | Zongbing YouSummaryAffiliation: University of California Country: USA Publications
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Publications
Interleukin-17 receptor-like gene is a novel antiapoptotic gene highly expressed in androgen-independent prostate cancerZongbing You
Center for Tissue Regeneration and Repair, Department of Orthopaedic Surgery, School of Medicine, University of California, Davis, Sacramento, California 95817, USA
Cancer Res 66:175-83. 2006..Thus, IL-17RL is a potential therapeutic target in the treatment of prostate cancer...
Differential expression of IL-17RC isoforms in androgen-dependent and androgen-independent prostate cancersZongbing You
The Lawrence Ellison Center for Tissue Regeneration and Repair, Department of Orthopedic Surgery, School of Medicine, University of California Davis, Sacramento, CA 95817, USA
Neoplasia 9:464-70. 2007..These observations provide evidence that IL-17RC protein isoforms are differentially expressed in prostatic cells and cancer tissues and may play a negative or positive role in the initiation and progression of prostate cancer...
Expression of interleukin-17B in mouse embryonic limb buds and regulation by BMP-7 and bFGFZongbing You
Department of Orthopaedic Surgery, Center for Tissue Regeneration and Repair, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA
Biochem Biophys Res Commun 326:624-31. 2005..This study provides the first evidence that IL-17B is expressed in the mouse embryonic limb buds and may play a role in chondrogenesis and osteogenesis...
Mechanical compression of articular cartilage induces chondrocyte proliferation and inhibits proteoglycan synthesis by activation of the ERK pathway: implications for tissue engineering and regenerative medicineJames A Ryan
Center for Tissue Regeneration and Repair, Lawrence Ellison Musculoskeletal Research Center, Department of Orthopedic Surgery, University of California at Davis, Sacramento, CA 95817, USA
J Tissue Eng Regen Med 3:107-16. 2009..In conclusion, the ERK 1/2 pathway is involved in the proliferative and biosynthetic response of chondrocytes following acute static mechanical compression...
Doublecortin is expressed in articular chondrocytesYi Zhang
Lawrence Ellison Center for Tissue Regeneration and Repair, Department of Orthopaedic Surgery, School of Medicine, University of California Davis, 4635 Second Avenue, Room 2000, Sacramento, CA 95817, USA
Biochem Biophys Res Commun 363:694-700. 2007....
Midkine is a NF-kappaB-inducible gene that supports prostate cancer cell survivalZongbing You
Department of Orthopaedic Surgery, University of California, Davis, Sacramento, CA 95817, USA
BMC Med Genomics 1:6. 2008..However, little is known about the upstream factors and signaling mechanisms that regulate midkine gene expression...
Bone morphogenetic protein (BMP)-6 signaling and BMP antagonist noggin in prostate cancerDominik R Haudenschild
Center for Tissue Regeneration and Repair, Department of Orthopedic Surgery, School of Medicine, University of California, Davis, Sacramento, California 95817, USA
Cancer Res 64:8276-84. 2004....
Donor cell survival in a fresh osteochondral allograft at twenty-nine years. A case reportAmir A Jamali
Department of Orthopaedic Surgery, University of California Davis Medical Center, 4860 Y Street, 3800, Sacramento, CA 95817, USA
J Bone Joint Surg Am 89:166-9. 2007
In vitro cytotoxic effects of benzalkonium chloride in corticosteroid injection suspensionDaniel Davis
Tulane Institute of Sports Medicine, Department of Orthopaedic Surgery, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA
J Bone Joint Surg Am 92:129-37. 2010..The objective of the present in vitro study was to determine if an injectable corticosteroid suspension is toxic to articular chondrocytes and synovial cells...
Interleukin-17 promotes formation and growth of prostate adenocarcinoma in mouse modelsQiuyang Zhang
Department of Structural and Cellular Biology, School of Medicine, New Orleans, LA, USA
Cancer Res 72:2589-99. 2012....
Gene expression profiling of mouse articular and growth plate cartilageShintaro Yamane
Lawrence Ellison Center for Tissue Regeneration and Repair, Department of Orthopaedic Surgery, School of Medicine, University of California, Davis, Sacramento, California 95817, USA
Tissue Eng 13:2163-73. 2007..The results of this investigation will be of use in the evaluation of tissue engineered cartilage...
c-Myc sensitizes cells to tumor necrosis factor-mediated apoptosis by inhibiting nuclear factor kappa B transactivationZongbing You
Laboratory of Molecular Signaling and Apoptosis, Department of Biologic and Materials Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA
J Biol Chem 277:36671-7. 2002..Our results elucidate the molecular mechanisms by which c-Myc increases cell susceptibility to TNF-mediated apoptosis, indicating that c-Myc may exhibit its pro-apoptotic activities by repression of cell survival genes...
Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosisZongbing You
Laboratory of Molecular Signaling and Apoptosis, Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor 48109-1078, USA
J Cell Biol 157:429-40. 2002..These results elucidate the molecular mechanisms by which Wnt/beta-catenin inhibits apoptosis and provide new insight into Wnt signaling-mediated oncogenesis...
Hepatocyte growth factor inhibits anoikis in head and neck squamous cell carcinoma cells by activation of ERK and Akt signaling independent of NFkappa BQinghua Zeng
Laboratory of Molecular Signaling and Apoptosis, Department of Biologic and Materials Sciences, University of Michigan, Ann Arbor 48109 1078, USA
J Biol Chem 277:25203-8. 2002..Taken together, our results suggest that anoikis resistance induced by HGF may also play an important role in the progression and metastasis of HNSCC...
