Weon Kyoo You
Affiliation: University of California
- The hepatocyte growth factor/c-Met signaling pathway as a therapeutic target to inhibit angiogenesisWeon Kyoo You
Department of Anatomy, University of California, San Francisco, California, USA
BMB Rep 41:833-9. 2008..The HGF/c-Met signaling pathway is now recognized as a promising target in cancer by inhibiting angiogenesis, tumor growth, invasion, and metastasis...
- Suppression of tumor invasion and metastasis by concurrent inhibition of c-Met and VEGF signaling in pancreatic neuroendocrine tumorsBarbara Sennino
Comprehensive Cancer Center, Department of Anatomy, University of California San Francisco UCSF, San Francisco, CA 94143 0452, USA
Cancer Discov 2:270-87. 2012..These findings document that invasion and metastasis are promoted by selective inhibition of VEGF signaling and can be reduced by the concurrent inhibition of c-Met...
- Ricinus communis agglutinin I leads to rapid down-regulation of VEGFR-2 and endothelial cell apoptosis in tumor blood vesselsWeon Kyoo You
Department of Anatomy, University of California, San Francisco, CA 94143 0452, USA
Am J Pathol 176:1927-40. 2010..Together, the results illustrate the selective impact of RCA I on VEGF signaling in tumor blood vessels...
- VEGF and c-Met blockade amplify angiogenesis inhibition in pancreatic islet cancerWeon Kyoo You
Cardiovascular Research Institute, Comprehensive Cancer Center, and Department of Anatomy, University of California, San Francisco, CA 94143, USA
Cancer Res 71:4758-68. 2011....
- Correlative dynamic contrast MRI and microscopic assessments of tumor vascularity in RIP-Tag2 transgenic miceBarbara Sennino
Department of Cardiovascular Research Institute, Comprehensive Cancer Center, University of California, San Francisco, California, USA
Magn Reson Med 62:616-25. 2009..356 mL/min/100 cm(3). Dynamic MMCM-enhanced MRI is feasible in RIP-Tag2 pancreatic tumors, yielding estimates of vascular permeability and microscopically validated measurements of vascular richness...
- In situ force mapping of mammary gland transformationJose I Lopez
Department of Surgery and Center for Bioengineering and Tissue Regeneration, University of California at San Francisco, 513 Parnassus Ave, HSE 565, San Francisco, CA 94143 0456, USA
Integr Biol (Camb) 3:910-21. 2011....