Research Topics
| Jong H YoonSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Automated classification of fMRI during cognitive control identifies more severely disorganized subjects with schizophreniaJong H Yoon
Department of Psychiatry and Imaging Research Center, University of California Davis School of Medicine, Sacramento CA, USA
Schizophr Res 135:28-33. 2012..Independent validation of classification-based phenotypes using other biological data such as genetics would provide a strong test of this hypothesis...
GABA concentration is reduced in visual cortex in schizophrenia and correlates with orientation-specific surround suppressionJong H Yoon
Department of Psychiatry and Imaging Research Center, University of California, Davis, Davis, California 95817, USA
J Neurosci 30:3777-81. 2010..10). These results suggest that a neocortical GABA deficit in subjects with schizophrenia leads to impaired cortical inhibition and that GABAergic synaptic transmission in visual cortex plays a critical role in OSSS...
Diminished orientation-specific surround suppression of visual processing in schizophreniaJong H Yoon
Department of Psychiatry and Imaging Research Center, University of California Davis, 4701 X Street, Sacramento, CA 95817, USA
Schizophr Bull 35:1078-84. 2009..In conjunction with physiological and anatomical evidence from basic and postmortem studies, our results suggest a deficit of inhibition in primary visual cortex in schizophrenia...
Differential effects of distraction during working memory on delay-period activity in the prefrontal cortex and the visual association cortexJong H Yoon
Henry H Wheeler Jr Brain Imaging Center, 132 Barker Hall, University of California Berkeley, Berkeley, CA 94720 1650, USA
Neuroimage 29:1117-26. 2006..Furthermore, persistent coactivation between the PFC and sensory areas may be a mechanism by which information is actively maintained...
Multivariate pattern analysis of functional magnetic resonance imaging data reveals deficits in distributed representations in schizophreniaJong H Yoon
Department of Psychiatry and Imaging Research Center, University of California Davis, Sacramento, California 95817, USA
Biol Psychiatry 64:1035-41. 2008..We applied this method to test the hypothesis of the impairment in distributed representations in schizophrenia. We also compared the results of this method with traditional general linear model (GLM)-based univariate analysis...
Segregation of function in the lateral prefrontal cortex during visual object working memoryJong H Yoon
Department of Psychiatry, University of California Davis, Sacramento, CA 95817, USA
Brain Res 1184:217-25. 2007..Our results suggest that the ventrolateral PFC supports retrospective sensory representations while the dorsolateral PFC supports prospective action representations...
Preserved function of the fusiform face area in schizophrenia as revealed by fMRIJong H Yoon
University of California Davis Imaging Research Center, Department of Psychiatry and Behavioral Sciences, University of California Davis, 4701 X St, Sacramento, CA 95817, USA
Psychiatry Res 148:205-16. 2006..The FFA, a critical region in the neural system subserving the perceptual processing of faces, appears to be intact in schizophrenia. These results call into question the presence of a specific face processing deficit in schizophrenia...
Prefrontal cortical deficits and impaired cognition-emotion interactions in schizophreniaStefan Ursu
Department of Psychiatry and Behavioral Sciences, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA
Am J Psychiatry 168:276-85. 2011....
Modafinil modulation of the default mode networkMichael J Minzenberg
Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA, USA
Psychopharmacology (Berl) 215:23-31. 2011..How this network is modulated by neurochemical systems during functional brain activity is not yet understood...
Association of dorsolateral prefrontal cortex dysfunction with disrupted coordinated brain activity in schizophrenia: relationship with impaired cognition, behavioral disorganization, and global functionJong H Yoon
Department of Psychiatry and Imaging Research Center, University of California, Davis, Sacramento, Calif 95817, USA
Am J Psychiatry 165:1006-14. 2008....
Gamma oscillatory power is impaired during cognitive control independent of medication status in first-episode schizophreniaMichael J Minzenberg
Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA 95817, USA
Neuropsychopharmacology 35:2590-9. 2010..This suggests that altered local circuit function supporting high-frequency oscillatory activity in prefrontal cortex ensembles may serve as the pathophysiological substrate of cognitive control deficits in schizophrenia...
Excessive contralateral motor overflow in schizophrenia measured by fMRIMichael J Minzenberg
Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA, USA
Psychiatry Res 202:38-45. 2012..This pathological motor overflow may be partly due to altered modulation of intended movement within the basal ganglia and premotor cortex...
Modafinil shifts human locus coeruleus to low-tonic, high-phasic activity during functional MRIMichael J Minzenberg
Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA, USA
Science 322:1700-2. 2008..These results confirm in humans the role of the LC-NE system in PFC function and cognitive control and suggest a mechanism for therapeutic action of procognitive noradrenergic agents...
Broader visual orientation tuning in patients with schizophreniaAriel Rokem
Helen Wills Neuroscience Institute, University of California Berkeley, CA, USA
Front Hum Neurosci 5:127. 2011..These results suggest that our finding of broader orientation tuning in SZ may be due to diminished visual cortical GABA levels...
Abnormal activity-dependent brain lactate and glutamate+glutamine responses in panic disorderRichard J Maddock
Department of Psychiatry, University of California Davis Medical Center, Sacramento, California Department of Imaging Research Center, University of California Davis Medical Center, Sacramento, California Electronic address
Biol Psychiatry 73:1111-9. 2013..However, prior studies in PD have not measured activity-dependent changes in brain metabolites other than lactate. Here we examine activity-dependent changes in both lactate and glutamate plus glutamine (glx) in PD...
An index of relative central α-adrenergic receptor antagonism by antipsychotic medicationsMichael J Minzenberg
Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA 95817, USA
Exp Clin Psychopharmacol 19:31-9. 2011..This index of HALα equivalents should facilitate the determination of the effects of α-adrenergic antagonism by these medications on clinical efficacy, side effects, and biological and cognitive measures of illness and treatment...
Research Grants
- fMRI Investigation of Active Maintenance in SchizophreniaJONG YOON; Fiscal Year: 2007..I plan to conduct these studies employing sophisticated neuroimaging and analytical techniques to examine the dynamic interactions of the DLPFC with the visual system. ..
