Jong H Yoon

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Impaired prefrontal-basal ganglia functional connectivity and substantia nigra hyperactivity in schizophrenia
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California Davis, Sacramento, CA 95817, USA
    Biol Psychiatry 74:122-9. 2013
  2. pmc Automated classification of fMRI during cognitive control identifies more severely disorganized subjects with schizophrenia
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California Davis School of Medicine, Sacramento CA, USA
    Schizophr Res 135:28-33. 2012
  3. ncbi request reprint Differential effects of distraction during working memory on delay-period activity in the prefrontal cortex and the visual association cortex
    Jong H Yoon
    Henry H Wheeler Jr Brain Imaging Center, 132 Barker Hall, University of California Berkeley, Berkeley, CA 94720 1650, USA
    Neuroimage 29:1117-26. 2006
  4. ncbi request reprint Preserved function of the fusiform face area in schizophrenia as revealed by fMRI
    Jong H Yoon
    University of California Davis Imaging Research Center, Department of Psychiatry and Behavioral Sciences, University of California Davis, 4701 X St, Sacramento, CA 95817, USA
    Psychiatry Res 148:205-16. 2006
  5. ncbi request reprint Segregation of function in the lateral prefrontal cortex during visual object working memory
    Jong H Yoon
    Department of Psychiatry, University of California Davis, Sacramento, CA 95817, USA
    Brain Res 1184:217-25. 2007
  6. pmc Multivariate pattern analysis of functional magnetic resonance imaging data reveals deficits in distributed representations in schizophrenia
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California Davis, Sacramento, California 95817, USA
    Biol Psychiatry 64:1035-41. 2008
  7. pmc Diminished orientation-specific surround suppression of visual processing in schizophrenia
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California Davis, 4701 X Street, Sacramento, CA 95817, USA
    Schizophr Bull 35:1078-84. 2009
  8. pmc GABA concentration is reduced in visual cortex in schizophrenia and correlates with orientation-specific surround suppression
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California, Davis, Davis, California 95817, USA
    J Neurosci 30:3777-81. 2010
  9. pmc Prefrontal cortical deficits and impaired cognition-emotion interactions in schizophrenia
    Stefan Ursu
    Department of Psychiatry and Behavioral Sciences, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA
    Am J Psychiatry 168:276-85. 2011
  10. pmc Modafinil modulation of the default mode network
    Michael J Minzenberg
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA, USA
    Psychopharmacology (Berl) 215:23-31. 2011

Research Grants

Detail Information

Publications20

  1. pmc Impaired prefrontal-basal ganglia functional connectivity and substantia nigra hyperactivity in schizophrenia
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California Davis, Sacramento, CA 95817, USA
    Biol Psychiatry 74:122-9. 2013
    ..We undertook this event-related functional magnetic resonance imaging study to test the hypothesis that PFC dysfunction is associated with altered function of and connectivity with dopamine regulating regions of the basal ganglia...
  2. pmc Automated classification of fMRI during cognitive control identifies more severely disorganized subjects with schizophrenia
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California Davis School of Medicine, Sacramento CA, USA
    Schizophr Res 135:28-33. 2012
    ..Independent validation of classification-based phenotypes using other biological data such as genetics would provide a strong test of this hypothesis...
  3. ncbi request reprint Differential effects of distraction during working memory on delay-period activity in the prefrontal cortex and the visual association cortex
    Jong H Yoon
    Henry H Wheeler Jr Brain Imaging Center, 132 Barker Hall, University of California Berkeley, Berkeley, CA 94720 1650, USA
    Neuroimage 29:1117-26. 2006
    ..Furthermore, persistent coactivation between the PFC and sensory areas may be a mechanism by which information is actively maintained...
  4. ncbi request reprint Preserved function of the fusiform face area in schizophrenia as revealed by fMRI
    Jong H Yoon
    University of California Davis Imaging Research Center, Department of Psychiatry and Behavioral Sciences, University of California Davis, 4701 X St, Sacramento, CA 95817, USA
    Psychiatry Res 148:205-16. 2006
    ..The FFA, a critical region in the neural system subserving the perceptual processing of faces, appears to be intact in schizophrenia. These results call into question the presence of a specific face processing deficit in schizophrenia...
  5. ncbi request reprint Segregation of function in the lateral prefrontal cortex during visual object working memory
    Jong H Yoon
    Department of Psychiatry, University of California Davis, Sacramento, CA 95817, USA
    Brain Res 1184:217-25. 2007
    ..Our results suggest that the ventrolateral PFC supports retrospective sensory representations while the dorsolateral PFC supports prospective action representations...
  6. pmc Multivariate pattern analysis of functional magnetic resonance imaging data reveals deficits in distributed representations in schizophrenia
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California Davis, Sacramento, California 95817, USA
    Biol Psychiatry 64:1035-41. 2008
    ..We applied this method to test the hypothesis of the impairment in distributed representations in schizophrenia. We also compared the results of this method with traditional general linear model (GLM)-based univariate analysis...
  7. pmc Diminished orientation-specific surround suppression of visual processing in schizophrenia
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California Davis, 4701 X Street, Sacramento, CA 95817, USA
    Schizophr Bull 35:1078-84. 2009
    ..In conjunction with physiological and anatomical evidence from basic and postmortem studies, our results suggest a deficit of inhibition in primary visual cortex in schizophrenia...
  8. pmc GABA concentration is reduced in visual cortex in schizophrenia and correlates with orientation-specific surround suppression
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California, Davis, Davis, California 95817, USA
    J Neurosci 30:3777-81. 2010
    ..10). These results suggest that a neocortical GABA deficit in subjects with schizophrenia leads to impaired cortical inhibition and that GABAergic synaptic transmission in visual cortex plays a critical role in OSSS...
  9. pmc Prefrontal cortical deficits and impaired cognition-emotion interactions in schizophrenia
    Stefan Ursu
    Department of Psychiatry and Behavioral Sciences, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA
    Am J Psychiatry 168:276-85. 2011
    ....
  10. pmc Modafinil modulation of the default mode network
    Michael J Minzenberg
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA, USA
    Psychopharmacology (Berl) 215:23-31. 2011
    ..How this network is modulated by neurochemical systems during functional brain activity is not yet understood...
  11. doi request reprint Excessive contralateral motor overflow in schizophrenia measured by fMRI
    Michael J Minzenberg
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA, USA
    Psychiatry Res 202:38-45. 2012
    ..This pathological motor overflow may be partly due to altered modulation of intended movement within the basal ganglia and premotor cortex...
  12. pmc Association of dorsolateral prefrontal cortex dysfunction with disrupted coordinated brain activity in schizophrenia: relationship with impaired cognition, behavioral disorganization, and global function
    Jong H Yoon
    Department of Psychiatry and Imaging Research Center, University of California, Davis, Sacramento, Calif 95817, USA
    Am J Psychiatry 165:1006-14. 2008
    ....
  13. pmc Gamma oscillatory power is impaired during cognitive control independent of medication status in first-episode schizophrenia
    Michael J Minzenberg
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA 95817, USA
    Neuropsychopharmacology 35:2590-9. 2010
    ..This suggests that altered local circuit function supporting high-frequency oscillatory activity in prefrontal cortex ensembles may serve as the pathophysiological substrate of cognitive control deficits in schizophrenia...
  14. ncbi request reprint Modafinil augments oscillatory power in middle frequencies during rule selection
    Michael J Minzenberg
    Department of Psychiatry, University of California, San Francisco School of Medicine, San Francisco, California, USA San Francisco Veterans Affairs Medical Center, San Francisco, California, USA
    Psychophysiology 51:510-9. 2014
    ..Augmentation of catecholamine signaling enhances middle-frequency cortical oscillatory power associated with rule selection, which may subserve diverse subcomponent processes in proactive cognitive control. ..
  15. ncbi request reprint Modafinil shifts human locus coeruleus to low-tonic, high-phasic activity during functional MRI
    Michael J Minzenberg
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA, USA
    Science 322:1700-2. 2008
    ..These results confirm in humans the role of the LC-NE system in PFC function and cognitive control and suggest a mechanism for therapeutic action of procognitive noradrenergic agents...
  16. pmc Abnormal activity-dependent brain lactate and glutamate+glutamine responses in panic disorder
    Richard J Maddock
    Department of Psychiatry, University of California Davis Medical Center, Sacramento, California 95817, USA
    Biol Psychiatry 73:1111-9. 2013
    ..However, prior studies in PD have not measured activity-dependent changes in brain metabolites other than lactate. Here we examine activity-dependent changes in both lactate and glutamate plus glutamine (glx) in PD...
  17. pmc Broader visual orientation tuning in patients with schizophrenia
    Ariel Rokem
    Helen Wills Neuroscience Institute, University of California Berkeley, CA, USA
    Front Hum Neurosci 5:127. 2011
    ..These results suggest that our finding of broader orientation tuning in SZ may be due to diminished visual cortical GABA levels...
  18. pmc Disrupted action monitoring in recent-onset psychosis patients with schizophrenia and bipolar disorder
    Michael J Minzenberg
    Department of Psychiatry, University of California, San Francisco School of Medicine, San Francisco, CA, United States Electronic address
    Psychiatry Res 221:114-21. 2014
    ..Antipsychotic medication may be associated with altered measures of error-monitoring in schizophrenia. ..
  19. ncbi request reprint Frontal cortex control dysfunction related to long-term suicide risk in recent-onset schizophrenia
    Michael J Minzenberg
    Department of Psychiatry, University of California, San Francisco School of Medicine, San Francisco, CA, United States Veterans Affairs Medical Center, San Francisco, CA, United States Electronic address
    Schizophr Res 157:19-25. 2014
    ..We tested whether PFC activity during goal-representation (an important component of cognitive control) relates to long-term suicide risk in recent-onset schizophrenia...
  20. doi request reprint An index of relative central α-adrenergic receptor antagonism by antipsychotic medications
    Michael J Minzenberg
    Department of Psychiatry, University of California, Davis School of Medicine, Sacramento, CA 95817, USA
    Exp Clin Psychopharmacol 19:31-9. 2011
    ..This index of HALα equivalents should facilitate the determination of the effects of α-adrenergic antagonism by these medications on clinical efficacy, side effects, and biological and cognitive measures of illness and treatment...

Research Grants2

  1. fMRI Investigation of Active Maintenance in Schizophrenia
    JONG YOON; Fiscal Year: 2007
    ..I plan to conduct these studies employing sophisticated neuroimaging and analytical techniques to examine the dynamic interactions of the DLPFC with the visual system. ..