Research Topics
Species | Qian YiSummaryAffiliation: University of Washington Country: USA Publications
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Detail Information
Publications
Integrating open-source technologies to build low-cost information systems for improved access to public health dataQian Yi
Center for Public Health Informatics, University of Washington, Seattle, Washington, USA
Int J Health Geogr 7:29. 2008....
Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibriumChristopher S Carlson
Department of Genome Sciences, University of Washington, Seattle, WA, 98195, USA
Am J Hum Genet 74:106-20. 2004..We demonstrate that, although common variation tends to be shared between populations, tagSNPs should be selected separately for populations with different ancestries...
Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populationsDana C Crawford
Department of Genome Sciences, University of Washington, Seattle 98195 7730, USA
Am J Hum Genet 74:610-22. 2004....
Sequence diversity, natural selection and linkage disequilibrium in the human T cell receptor alpha/delta locusRachel Mackelprang
Department of Genome Sciences, University of Washington, 357730, Seattle, WA, 98195 7730, USA
Hum Genet 119:255-66. 2006..Furthermore, we explore signatures of natural selection across V genes. We find evidence of strong directional selection at this locus as evidenced by unusually high values of Fst...
Allelic spectrum of the natural variation in CRPDana C Crawford
Department of Genome Sciences, University of Washington, 1705 NE Pacific, Seattle, WA 98195 7730, USA
Hum Genet 119:496-504. 2006..Collectively, these data suggest that several different types re-sequencing and genotyping approaches may be required to fully understand the complete spectrum of alleles that impact human phenotypes...
LPA and PLG sequence variation and kringle IV-2 copy number in two populationsDana C Crawford
Department of Molecular Physiology and Biophysics, Center for Human Genetics Research, Vanderbilt University, Nashville, TN 37232, USA
Hum Hered 66:199-209. 2008..African-descent populations have, on average, higher levels of Lp(a), suggesting other genetic factors contribute to Lp(a) level variability across populations...
Integrating host genomics with surveillance for invasive bacterial diseasesDana C Crawford
Vanderbilt University, Nashville, Tennessee, USA
Emerg Infect Dis 14:1138-40. 2008..Using nDBS specimens, we resequenced CD46, putative host gene receptor for Neisseria meningitidis, and identified variants associated with susceptibility to this disease...
