DEBORAH L YELON
Affiliation: University of California
Sidhwani P, Yelon D. Fluid forces shape the embryonic heart: Insights from zebrafish. Curr Top Dev Biol. 2019;132:395-416 pubmed publisher
..Over the long-term, this knowledge will undoubtedly guide our consideration of the potential causes of congenital heart disease. ..
Zeng X, Yelon D. Cadm4 restricts the production of cardiac outflow tract progenitor cells. Cell Rep. 2014;7:951-60 pubmed publisher
..Together, our data suggest a role for cell adhesion in restraining SHF deployment to the OFT, perturbation of which could cause congenital OFT defects. ..
Schindler Y, Garske K, Wang J, Firulli B, Firulli A, Poss K, et al
. Hand2 elevates cardiomyocyte production during zebrafish heart development and regeneration. Development. 2014;141:3112-22 pubmed publisher
..These results contribute to our understanding of the potential origins of congenital heart disease and inform future strategies in regenerative medicine. ..
Ryckebusch L, Hernandez L, Wang C, Phan J, Yelon D. Tmem2 regulates cell-matrix interactions that are essential for muscle fiber attachment. Development. 2016;143:2965-72 pubmed publisher
..These findings evoke possible connections between the functions of Tmem2 and the etiologies of congenital muscular dystrophies, particularly dystroglycanopathies. ..
Pradhan A, Zeng X, Sidhwani P, Marques S, George V, TARGOFF K, et al
. FGF signaling enforces cardiac chamber identity in the developing ventricle. Development. 2017;144:1328-1338 pubmed publisher
..Together, our data suggest a model in which sustained FGF signaling acts to suppress cardiomyocyte plasticity and to preserve the integrity of the ventricular chamber. ..