Research Topics
| Alvin T YehSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Reversible dissociation of collagen in tissuesAlvin T Yeh
Laser Microbeam and Medical Program, Beckman Laser Institute, University of California, Irvine, California, USA
J Invest Dermatol 121:1332-5. 2003..These results reveal the assembly process of high-order collagen structures and propose a molecular mechanism for the increase in tissue transparency observed after glycerol application...
Imaging wound healing using optical coherence tomography and multiphoton microscopy in an in vitro skin-equivalent tissue modelAlvin T Yeh
University of California, Beckman Laser Institute, Laser Microbeam and Medical Program, 1002 Health Sciences Road East, Irvine, California 92612, USA
J Biomed Opt 9:248-53. 2004..This study illustrates the complementary features of linear and nonlinear light-tissue interaction in intrinsic signal optical imaging and their use for noninvasive, serial monitoring of wound healing processes in biological tissues...
Photodynamic therapy on keloid fibroblasts in tissue-engineered keratinocyte-fibroblast co-cultureLynn L Chiu
Beckman Laser Institute, University of California Irvine, Irvine, California 92612, USA
Lasers Surg Med 37:231-44. 2005..Contraction and collagen density were greatest in keloid and neonatal Rafts. CONCLUSIONS: A PDT dosimetry range was established, which reduces tissue contraction and collagen density while minimizing injury to fibroblasts...
Modeling aberrant wound healing using tissue-engineered skin constructs and multiphoton microscopyBehrooz A Torkian
Department of Otolaryngology- Head and Neck Surgery, University of California, Irvine Medical Center, Irvine, CA 92612, USA
Arch Facial Plast Surg 6:180-7. 2004..Furthermore, it demonstrates the biologic activity of RAFT artificial tissue constructs...
Revisiting optical clearing with dimethyl sulfoxide (DMSO)Albert K Bui
School of Biological Sciences, University of California, Irvine, California 92697, USA
Lasers Surg Med 41:142-8. 2009..Collectively, our data demonstrate the potential of DMSO alone to mitigate effects of scattering, which we expect will improve molecular imaging studies...
Molecular interactions of exogenous chemical agents with collagen--implications for tissue optical clearingAlvin T Yeh
Texas A and M University, Department of Biomedical Engineering, 337 Zachry Engineering Center, 3120 TAMU, College Station, Texas 77843, USA
J Biomed Opt 11:014003. 2006..A mechanism of tissue optical clearing is proposed based on agent destabilization of high-order collagen structures...
Advances in nonlinear optical microscopy for visualizing dynamic tissue properties in cultureAlvin T Yeh
Department of Biomedical Engineering, Texas A and M University, College Staion, TX 77843, USA
Tissue Eng Part B Rev 14:119-31. 2008....
Influence of glycerol on the mechanical reversibility and thermal damage susceptibility of collagenous tissuesPaul B Wells
Texas A and M University, College Station, TX 7784, USA
IEEE Trans Biomed Eng 53:747-53. 2006..Moreover, glycerol protects cleared tissue by increasing its thermal stability and minimizing thermal alterations of mechanical properties...
Nonlinear optical microscopy of articular cartilageAlvin T Yeh
Department of Biomedical Engineering, Texas A and M University, College Station, TX 77843, USA
Osteoarthritis Cartilage 13:345-52. 2005..NLOM was sensitive to macromolecular composition and pathologic changes in articular cartilage matrix. Advances in instrumentation may lead to the application of NLOM to study articular cartilage in vivo...
Collagen solubility correlates with skin optical clearingJason Hirshburg
J Biomed Opt 11:040501. 2006..Herein we show that a chemical agent's tissue optical clearing potential is directly related to its collagen solubility, providing a rational design basis for effective, percutaneous formulations...
Correlation between collagen solubility and skin optical clearing using sugarsJason Hirshburg
Department of Biomedical Engineering, Texas A and M University, 337 Zachry Engineering Center, 3120 TAMU, College Station, Texas 77843, USA
Lasers Surg Med 39:140-4. 2007..This study examines the correlation between collagen solubility and the optical clearing potential (OCP) of sugars and sugar-alcohols using in vitro rodent skin...
Rabbit cornea microstructure response to changes in intraocular pressure visualized by using nonlinear optical microscopyQiaofeng Wu
Department of Biomedical Engineering, Texas A and M University, College Station, TX 77843, USA
Cornea 27:202-8. 2008..To characterize the microstructural response of the rabbit cornea to changes in intraocular pressure (IOP) by using nonlinear optical microscopy (NLOM)...
Delivery of sub-10-fs pulses for nonlinear optical microscopy by polarization-maintaining single mode optical fiberAdam M Larson
Department of Biomedical Engineering, Texas A and M University, College Station, TX 77843, USA
Opt Express 16:14723-30. 2008....
Ex vivo characterization of sub-10-fs pulsesAdam M Larson
Departmetn of Biomedical Engineering, Texas A and M University, Texas 77843, USA
Opt Lett 31:1681-3. 2006..Compensated autocorrelation traces are presented for biologically relevant objective lenses...
