Michael E Yeager

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. pmc Plasma proteomics of differential outcome to long-term therapy in children with idiopathic pulmonary arterial hypertension
    Michael E Yeager
    Department of Pediatric Critical Care, University of Colorado Denver, Denver, CO 80045, USA
    Proteomics Clin Appl 6:257-67. 2012
  2. pmc Circulating myeloid-derived suppressor cells are increased and activated in pulmonary hypertension
    Michael E Yeager
    Department of Pediatrics, Division of Pulmonary and Critical Care Medicine, University of Colorado, Denver, Aurora, CO 80045, USA
    Chest 141:944-52. 2012
  3. pmc Circulating fibrocytes are increased in children and young adults with pulmonary hypertension
    M E Yeager
    Dept of Paediatrics, Division of Pulmonary and Critical Care Medicine, University of Colorado Denver, Aurora, CO 80045, USA
    Eur Respir J 39:104-11. 2012
  4. pmc Endothelin-1, the unfolded protein response, and persistent inflammation: role of pulmonary artery smooth muscle cells
    Michael E Yeager
    Division of Pulmonary, and Critical Care Medicine, Department of Pediatrics, University of Colorado at Denver, Aurora, 80138, USA
    Am J Respir Cell Mol Biol 46:14-22. 2012
  5. pmc The adventitia: essential regulator of vascular wall structure and function
    Kurt R Stenmark
    Division of Pediatric Critical Care, University of Colorado Denver, Aurora, Colorado 80045, USA
    Annu Rev Physiol 75:23-47. 2013
  6. doi Class I HDACs regulate angiotensin II-dependent cardiac fibrosis via fibroblasts and circulating fibrocytes
    Sarah M Williams
    Department of Medicine, Division of Cardiology, University of Colorado Denver, Aurora, CO, USA
    J Mol Cell Cardiol 67:112-25. 2014
  7. pmc Superoxide dismutase mimetic, MnTE-2-PyP, attenuates chronic hypoxia-induced pulmonary hypertension, pulmonary vascular remodeling, and activation of the NALP3 inflammasome
    Leah R Villegas
    Department of Pediatrics, University of Colorado, Aurora, CO 80045, USA
    Antioxid Redox Signal 18:1753-64. 2013
  8. pmc Activation of the unfolded protein response is associated with pulmonary hypertension
    Michael E Yeager
    Department of Pediatrics, Division of Pulmonary and Critical Care Medicine, University of Colorado Denver, Aurora, Colorado, USA
    Pulm Circ 2:229-40. 2012
  9. pmc Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension
    Min Li
    Division of Critical Care Medicine, Department of Pediatrics, University of Colorado at Denver, Aurora, CO 80045, USA
    J Immunol 187:2711-22. 2011
  10. pmc Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism
    Maria A Cavasin
    Department of Medicine, Division of Cardiology, University of Colorado Denver, Aurora, CO, USA
    Circ Res 110:739-48. 2012

Collaborators

Detail Information

Publications10

  1. pmc Plasma proteomics of differential outcome to long-term therapy in children with idiopathic pulmonary arterial hypertension
    Michael E Yeager
    Department of Pediatric Critical Care, University of Colorado Denver, Denver, CO 80045, USA
    Proteomics Clin Appl 6:257-67. 2012
    ..The prognosis for children with IPAH unresponsive to therapy is poor. We investigated the plasma proteome for a molecular basis of good versus poor outcome to long-term vasodilator therapy...
  2. pmc Circulating myeloid-derived suppressor cells are increased and activated in pulmonary hypertension
    Michael E Yeager
    Department of Pediatrics, Division of Pulmonary and Critical Care Medicine, University of Colorado, Denver, Aurora, CO 80045, USA
    Chest 141:944-52. 2012
    ..Immature myeloid cells are found in the lungs of humans and animals with PH, and we hypothesized that they would be increased in the blood of patients with PH compared with control subjects...
  3. pmc Circulating fibrocytes are increased in children and young adults with pulmonary hypertension
    M E Yeager
    Dept of Paediatrics, Division of Pulmonary and Critical Care Medicine, University of Colorado Denver, Aurora, CO 80045, USA
    Eur Respir J 39:104-11. 2012
    ..We speculate that these cells might play important roles in vascular remodelling in children and young adults with pulmonary hypertension...
  4. pmc Endothelin-1, the unfolded protein response, and persistent inflammation: role of pulmonary artery smooth muscle cells
    Michael E Yeager
    Division of Pulmonary, and Critical Care Medicine, Department of Pediatrics, University of Colorado at Denver, Aurora, 80138, USA
    Am J Respir Cell Mol Biol 46:14-22. 2012
    ....
  5. pmc The adventitia: essential regulator of vascular wall structure and function
    Kurt R Stenmark
    Division of Pediatric Critical Care, University of Colorado Denver, Aurora, Colorado 80045, USA
    Annu Rev Physiol 75:23-47. 2013
    ..This review presents the current evidence demonstrating that the adventitia acts as a key regulator of vascular wall function and structure from the outside in...
  6. doi Class I HDACs regulate angiotensin II-dependent cardiac fibrosis via fibroblasts and circulating fibrocytes
    Sarah M Williams
    Department of Medicine, Division of Cardiology, University of Colorado Denver, Aurora, CO, USA
    J Mol Cell Cardiol 67:112-25. 2014
    ....
  7. pmc Superoxide dismutase mimetic, MnTE-2-PyP, attenuates chronic hypoxia-induced pulmonary hypertension, pulmonary vascular remodeling, and activation of the NALP3 inflammasome
    Leah R Villegas
    Department of Pediatrics, University of Colorado, Aurora, CO 80045, USA
    Antioxid Redox Signal 18:1753-64. 2013
    ....
  8. pmc Activation of the unfolded protein response is associated with pulmonary hypertension
    Michael E Yeager
    Department of Pediatrics, Division of Pulmonary and Critical Care Medicine, University of Colorado Denver, Aurora, Colorado, USA
    Pulm Circ 2:229-40. 2012
    ..As such, understanding the functional contributions of the UPR in the setting of PH may have important therapeutic implications...
  9. pmc Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension
    Min Li
    Division of Critical Care Medicine, Department of Pediatrics, University of Colorado at Denver, Aurora, CO 80045, USA
    J Immunol 187:2711-22. 2011
    ....
  10. pmc Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism
    Maria A Cavasin
    Department of Medicine, Division of Cardiology, University of Colorado Denver, Aurora, CO, USA
    Circ Res 110:739-48. 2012
    ..The consequences of HDAC inhibition in the context of pulmonary hypertension with associated right ventricular cardiac remodeling are poorly understood...