Affiliation: University of Rochester
- Roscovitine inhibits CaV3.1 (T-type) channels by preferentially affecting closed-state inactivationViktor Yarotskyy
Department of Pharmacology and Physiology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA
J Pharmacol Exp Ther 340:463-72. 2012..The ability of roscovitine to block multiple mediators of proliferation, including CDKs and Ca(V)3.1 channels, may facilitate its anticancer properties...