Humphrey Hung Chang Yao

Summary

Affiliation: University of Illinois
Country: USA

Publications

  1. ncbi request reprint The pathway to femaleness: current knowledge on embryonic development of the ovary
    Humphrey Hung Chang Yao
    Department of Veterinary Biosciences, University of Illinois at Urbana Champaign, IL 61802, USA
    Mol Cell Endocrinol 230:87-93. 2005
  2. pmc Sexually dimorphic regulation of inhibin beta B in establishing gonadal vasculature in mice
    Humphrey Hung Chang Yao
    Department of Veterinary Biosciences, University of Illinois at Urbana Champaign, Urbana, Illinois 61802, USA
    Biol Reprod 74:978-83. 2006
  3. pmc Investigating the role of adrenal cortex in organization and differentiation of the adrenal medulla in mice
    Chen Che Jeff Huang
    Department of Comparative Biosciences, University of Illinois at Urbana Champaign, Urbana, IL, USA
    Mol Cell Endocrinol 361:165-71. 2012
  4. pmc Testicular somatic cells, not gonocytes, are the major source of functional activin A during testis morphogenesis
    Denise R Archambeault
    Department of Comparative Biosciences, University of Illinois, Urbana, IL 61802, USA
    Endocrinology 152:4358-67. 2011
  5. pmc Activin A, a product of fetal Leydig cells, is a unique paracrine regulator of Sertoli cell proliferation and fetal testis cord expansion
    Denise R Archambeault
    Department of Veterinary Biosciences, University of Illinois, Urbana, IL 61802, USA
    Proc Natl Acad Sci U S A 107:10526-31. 2010
  6. pmc Investigating the origins of somatic cell populations in the perinatal mouse ovaries using genetic lineage tracing and immunohistochemistry
    Chang Liu
    Department of Animal Sciences, University of Illinois at Urbana Champaign, Urbana, IL, USA
    Methods Mol Biol 825:211-21. 2012
  7. pmc Essential roles of inhibin beta A in mouse epididymal coiling
    Jessica Tomaszewski
    Department of Biology, School of Integrative Biology, University of Illinois at Urbana Champaign, Urbana, IL 61802, USA
    Proc Natl Acad Sci U S A 104:11322-7. 2007
  8. ncbi request reprint The road to maleness: from testis to Wolffian duct
    Ivraym Barsoum
    Departments of Cell and Developmental Biology and Department of Veterinary Biosciences, University of Illinois, Urbana, IL 61802, USA
    Trends Endocrinol Metab 17:223-8. 2006
  9. pmc Diverse functions of Hedgehog signaling in formation and physiology of steroidogenic organs
    Chen Che Jeff Huang
    Department of Veterinary Biosciences, University of Illinois, Urbana, IL 61802, USA
    Mol Reprod Dev 77:489-96. 2010
  10. pmc Dynamic changes in fetal Leydig cell populations influence adult Leydig cell populations in mice
    Ivraym B Barsoum
    Department of Comparative Biosciences, College of Veterinary Medicine, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
    FASEB J 27:2657-66. 2013

Collaborators

Detail Information

Publications14

  1. ncbi request reprint The pathway to femaleness: current knowledge on embryonic development of the ovary
    Humphrey Hung Chang Yao
    Department of Veterinary Biosciences, University of Illinois at Urbana Champaign, IL 61802, USA
    Mol Cell Endocrinol 230:87-93. 2005
    ..Challenges await us to establish the molecular connections of these molecules as well as to discover new candidates in the pathway of early ovarian development...
  2. pmc Sexually dimorphic regulation of inhibin beta B in establishing gonadal vasculature in mice
    Humphrey Hung Chang Yao
    Department of Veterinary Biosciences, University of Illinois at Urbana Champaign, Urbana, Illinois 61802, USA
    Biol Reprod 74:978-83. 2006
    ..Inhibin beta B is strategically positioned at the intersection of these opposing pathways...
  3. pmc Investigating the role of adrenal cortex in organization and differentiation of the adrenal medulla in mice
    Chen Che Jeff Huang
    Department of Comparative Biosciences, University of Illinois at Urbana Champaign, Urbana, IL, USA
    Mol Cell Endocrinol 361:165-71. 2012
    ....
  4. pmc Testicular somatic cells, not gonocytes, are the major source of functional activin A during testis morphogenesis
    Denise R Archambeault
    Department of Comparative Biosciences, University of Illinois, Urbana, IL 61802, USA
    Endocrinology 152:4358-67. 2011
    ....
  5. pmc Activin A, a product of fetal Leydig cells, is a unique paracrine regulator of Sertoli cell proliferation and fetal testis cord expansion
    Denise R Archambeault
    Department of Veterinary Biosciences, University of Illinois, Urbana, IL 61802, USA
    Proc Natl Acad Sci U S A 107:10526-31. 2010
    ..Our findings challenge the paradigm that fetal testis development is solely under the control of Sertoli cells, by uncovering an active and essential role of fetal Leydig cells during testis cord morphogenesis...
  6. pmc Investigating the origins of somatic cell populations in the perinatal mouse ovaries using genetic lineage tracing and immunohistochemistry
    Chang Liu
    Department of Animal Sciences, University of Illinois at Urbana Champaign, Urbana, IL, USA
    Methods Mol Biol 825:211-21. 2012
    ..Here, we describe how to apply the genetic lineage tracing model in combination with immunohistochemistry to identify the potential origins of somatic cell precursors in perinatal mouse ovaries...
  7. pmc Essential roles of inhibin beta A in mouse epididymal coiling
    Jessica Tomaszewski
    Department of Biology, School of Integrative Biology, University of Illinois at Urbana Champaign, Urbana, IL 61802, USA
    Proc Natl Acad Sci U S A 104:11322-7. 2007
    ..These results demonstrated that Inhba, a mesenchyme-specific gene, acts collectively with testosterone to facilitate epididymal coiling by stimulating epithelial proliferation...
  8. ncbi request reprint The road to maleness: from testis to Wolffian duct
    Ivraym Barsoum
    Departments of Cell and Developmental Biology and Department of Veterinary Biosciences, University of Illinois, Urbana, IL 61802, USA
    Trends Endocrinol Metab 17:223-8. 2006
    ..Recent advancement of genetic and genomic approaches has unveiled the molecular pathways for differentiation of Sertoli cells and Leydig cells as well as development of the Wolffian duct...
  9. pmc Diverse functions of Hedgehog signaling in formation and physiology of steroidogenic organs
    Chen Che Jeff Huang
    Department of Veterinary Biosciences, University of Illinois, Urbana, IL 61802, USA
    Mol Reprod Dev 77:489-96. 2010
    ..The purpose of this review is to compare and contrast the different roles of Hh signaling in these three organs during development...
  10. pmc Dynamic changes in fetal Leydig cell populations influence adult Leydig cell populations in mice
    Ivraym B Barsoum
    Department of Comparative Biosciences, College of Veterinary Medicine, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
    FASEB J 27:2657-66. 2013
    ..These defects highlight the importance of properly regulated Hh signaling in Leydig cell development and testicular functions...
  11. pmc Progenitor cell expansion and organ size of mouse adrenal is regulated by sonic hedgehog
    Chen Che Jeff Huang
    Department of Veterinary Biosciences, University of Illinois, 2001 South Lincoln Avenue, Urbana, Illinois 61802, USA
    Endocrinology 151:1119-28. 2010
    ..Our results not only provide the genetic evidence to support that the adrenal capsule contributes to the growth of adrenocortex in both fetal and adult life but also identify a novel role of Shh in this process...
  12. pmc Stem cell potential of the mammalian gonad
    Chia Feng Liu
    Department of Veterinary Biosciences, University of Illinois at Urbana Champaign, Urbana, IL 61802, USA
    Front Biosci (Elite Ed) 1:510-8. 2009
    ..In this review, we discuss studies focusing on whether stem cell properties are present in the different cell types of male and female gonads and their implications on stem cell research...
  13. pmc Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis
    Humphrey Hung Chang Yao
    Department of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Genes Dev 16:1433-40. 2002
    ....
  14. ncbi request reprint The battle of the sexes: opposing pathways in sex determination
    Humphrey Hung Chang Yao
    Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
    Novartis Found Symp 244:187-98; discussion 198-206, 253-7. 2002
    ..Current experiments in the lab address the hypothesis that cord formation and germ cell entry into meiosis are competing pathways in gonad development...