Research Topics
Genomes and Genes
Species | Humphrey Hung Chang YaoSummaryAffiliation: University of Illinois Country: USA Publications
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Detail Information
Publications
The pathway to femaleness: current knowledge on embryonic development of the ovaryHumphrey Hung Chang Yao
Department of Veterinary Biosciences, University of Illinois at Urbana Champaign, IL 61802, USA
Mol Cell Endocrinol 230:87-93. 2005..Challenges await us to establish the molecular connections of these molecules as well as to discover new candidates in the pathway of early ovarian development...
Sexually dimorphic regulation of inhibin beta B in establishing gonadal vasculature in miceHumphrey Hung Chang Yao
Department of Veterinary Biosciences, University of Illinois at Urbana Champaign, Urbana, Illinois 61802, USA
Biol Reprod 74:978-83. 2006..Inhibin beta B is strategically positioned at the intersection of these opposing pathways...
Testicular somatic cells, not gonocytes, are the major source of functional activin A during testis morphogenesisDenise R Archambeault
Department of Comparative Biosciences, University of Illinois, Urbana, IL 61802, USA
Endocrinology 152:4358-67. 2011....
Activin A, a product of fetal Leydig cells, is a unique paracrine regulator of Sertoli cell proliferation and fetal testis cord expansionDenise R Archambeault
Department of Veterinary Biosciences, University of Illinois, Urbana, IL 61802, USA
Proc Natl Acad Sci U S A 107:10526-31. 2010..Our findings challenge the paradigm that fetal testis development is solely under the control of Sertoli cells, by uncovering an active and essential role of fetal Leydig cells during testis cord morphogenesis...
Investigating the origins of somatic cell populations in the perinatal mouse ovaries using genetic lineage tracing and immunohistochemistryChang Liu
Department of Animal Sciences, University of Illinois at Urbana Champaign, Urbana, IL, USA
Methods Mol Biol 825:211-21. 2012..Here, we describe how to apply the genetic lineage tracing model in combination with immunohistochemistry to identify the potential origins of somatic cell precursors in perinatal mouse ovaries...
Essential roles of inhibin beta A in mouse epididymal coilingJessica Tomaszewski
Department of Biology, School of Integrative Biology, University of Illinois at Urbana Champaign, Urbana, IL 61802, USA
Proc Natl Acad Sci U S A 104:11322-7. 2007..These results demonstrated that Inhba, a mesenchyme-specific gene, acts collectively with testosterone to facilitate epididymal coiling by stimulating epithelial proliferation...
Diverse functions of Hedgehog signaling in formation and physiology of steroidogenic organsChen Che Jeff Huang
Department of Veterinary Biosciences, University of Illinois, Urbana, IL 61802, USA
Mol Reprod Dev 77:489-96. 2010..The purpose of this review is to compare and contrast the different roles of Hh signaling in these three organs during development...
Progenitor cell expansion and organ size of mouse adrenal is regulated by sonic hedgehogChen Che Jeff Huang
Department of Veterinary Biosciences, University of Illinois, 2001 South Lincoln Avenue, Urbana, Illinois 61802, USA
Endocrinology 151:1119-28. 2010..Our results not only provide the genetic evidence to support that the adrenal capsule contributes to the growth of adrenocortex in both fetal and adult life but also identify a novel role of Shh in this process...
Stem cell potential of the mammalian gonadChia Feng Liu
Department of Veterinary Biosciences, University of Illinois at Urbana Champaign, Urbana, IL 61802, USA
Front Biosci (Elite Ed) 1:510-8. 2009..In this review, we discuss studies focusing on whether stem cell properties are present in the different cell types of male and female gonads and their implications on stem cell research...
Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesisHumphrey Hung Chang Yao
Department of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710, USA
Genes Dev 16:1433-40. 2002....
The battle of the sexes: opposing pathways in sex determinationHumphrey Hung-Chang Yao
Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
Novartis Found Symp 244:187-98; discussion 198-206, 253-7. 2002..Current experiments in the lab address the hypothesis that cord formation and germ cell entry into meiosis are competing pathways in gonad development...
