Chaoqun Yao

Summary

Affiliation: University of Wyoming
Country: USA

Publications

  1. pmc Leishmania chagasi: homogenous metacyclic promastigotes isolated by buoyant density are highly virulent in a mouse model
    Chaoqun Yao
    Department of Internal Medicine, University of Iowa, IA 52242, USA
    Exp Parasitol 118:129-33. 2008
  2. pmc Attenuation of Leishmania infantum chagasi metacyclic promastigotes by sterol depletion
    Chaoqun Yao
    Department of Veterinary Sciences and Wyoming State Veterinary Laboratory, University of Wyoming, Laramie, Wyoming, USA
    Infect Immun 81:2507-17. 2013
  3. doi Diagnosis of Tritrichomonas foetus-infected bulls, an ultimate approach to eradicate bovine trichomoniasis in US cattle?
    Chaoqun Yao
    Department of Veterinary Sciences, Wyoming State Veterinary Laboratory, University of Wyoming, Laramie, 82070, USA
    J Med Microbiol 62:1-9. 2013
  4. doi Filaroides osleri (Oslerus osleri): two case reports and a review of canid infections in North America
    Chaoqun Yao
    Department of Veterinary Sciences and Wyoming State Veterinary Laboratory, University of Wyoming, Laramie, WY 82070, USA
    Vet Parasitol 179:123-9. 2011
  5. pmc Proteomic examination of Leishmania chagasi plasma membrane proteins: Contrast between avirulent and virulent (metacyclic) parasite forms
    Chaoqun Yao
    Department of Internal Medicine, University of Iowa, Iowa City, USA
    Proteomics Clin Appl 4:4-16. 2010
  6. pmc Major surface protease of trypanosomatids: one size fits all?
    Chaoqun Yao
    Mailing address Department of Veterinary Sciences and Wyoming State Veterinary Laboratory, University of Wyoming, Laramie, WY 82070, USA
    Infect Immun 78:22-31. 2010
  7. pmc The major surface protease (MSP or GP63) in the intracellular amastigote stage of Leishmania chagasi
    Chia Hung Christine Hsiao
    Molecular Biology Program, University of Iowa, Iowa City, IA 52242, USA
    Mol Biochem Parasitol 157:148-59. 2008
  8. ncbi Internal and surface subpopulations of the major surface protease (MSP) of Leishmania chagasi
    Chaoqun Yao
    VA Medical Center, University of Iowa, Iowa City, IA 52242, USA
    Mol Biochem Parasitol 139:173-83. 2005
  9. pmc Leishmania chagasi: a tetracycline-inducible cell line driven by T7 RNA polymerase
    Chaoqun Yao
    Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA
    Exp Parasitol 116:205-13. 2007
  10. pmc Internal and surface-localized major surface proteases of Leishmania spp. and their differential release from promastigotes
    Chaoqun Yao
    Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA
    Eukaryot Cell 6:1905-12. 2007

Collaborators

  • JOHN DONELSON
  • YinZhu Jin
  • Chia Hung Christine Hsiao
  • Brant Schumaker
  • Jim Logan
  • Patricia Storlie
  • Mary E Wilson

Detail Information

Publications14

  1. pmc Leishmania chagasi: homogenous metacyclic promastigotes isolated by buoyant density are highly virulent in a mouse model
    Chaoqun Yao
    Department of Internal Medicine, University of Iowa, IA 52242, USA
    Exp Parasitol 118:129-33. 2008
    ..These metacyclic L. chagasi expressed both the virulence-associated 59-kDa, and the constitutively expressed 63-kDa, isoforms of MSP...
  2. pmc Attenuation of Leishmania infantum chagasi metacyclic promastigotes by sterol depletion
    Chaoqun Yao
    Department of Veterinary Sciences and Wyoming State Veterinary Laboratory, University of Wyoming, Laramie, Wyoming, USA
    Infect Immun 81:2507-17. 2013
    ..These data support the hypothesis that plasma membrane sterols are important for the virulence of Leishmania protozoa at least in part through retention of membrane virulence proteins...
  3. doi Diagnosis of Tritrichomonas foetus-infected bulls, an ultimate approach to eradicate bovine trichomoniasis in US cattle?
    Chaoqun Yao
    Department of Veterinary Sciences, Wyoming State Veterinary Laboratory, University of Wyoming, Laramie, 82070, USA
    J Med Microbiol 62:1-9. 2013
    ..Finally, a comprehensive approach for controlling and eventually eradicating the disease is presented...
  4. doi Filaroides osleri (Oslerus osleri): two case reports and a review of canid infections in North America
    Chaoqun Yao
    Department of Veterinary Sciences and Wyoming State Veterinary Laboratory, University of Wyoming, Laramie, WY 82070, USA
    Vet Parasitol 179:123-9. 2011
    ..It can be confirmed most readily by endoscopic detection of distinctive submucosal parasite-filled nodules, combined with histological examination of endoscopic biopsies...
  5. pmc Proteomic examination of Leishmania chagasi plasma membrane proteins: Contrast between avirulent and virulent (metacyclic) parasite forms
    Chaoqun Yao
    Department of Internal Medicine, University of Iowa, Iowa City, USA
    Proteomics Clin Appl 4:4-16. 2010
    ..We hypothesized that proteins important for promastigote virulence might be uniquely represented in the plasma membrane of metacyclic, but not procyclic, promastigotes...
  6. pmc Major surface protease of trypanosomatids: one size fits all?
    Chaoqun Yao
    Mailing address Department of Veterinary Sciences and Wyoming State Veterinary Laboratory, University of Wyoming, Laramie, WY 82070, USA
    Infect Immun 78:22-31. 2010
    ..The cellular locations and the extracellular release of MSPs are also discussed in connection with MSP functions in leishmanial promastigotes...
  7. pmc The major surface protease (MSP or GP63) in the intracellular amastigote stage of Leishmania chagasi
    Chia Hung Christine Hsiao
    Molecular Biology Program, University of Iowa, Iowa City, IA 52242, USA
    Mol Biochem Parasitol 157:148-59. 2008
    ..We hypothesize that MSP plays different roles in the extracellular versus intracellular forms of Leishmania spp...
  8. ncbi Internal and surface subpopulations of the major surface protease (MSP) of Leishmania chagasi
    Chaoqun Yao
    VA Medical Center, University of Iowa, Iowa City, IA 52242, USA
    Mol Biochem Parasitol 139:173-83. 2005
    ..These data are consistent with the hypothesis that the major mechanism regulating MSP abundance is the rate of loss of surface-localized MSP from the promastigote surface, and that internally localized MSP is very stable...
  9. pmc Leishmania chagasi: a tetracycline-inducible cell line driven by T7 RNA polymerase
    Chaoqun Yao
    Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA
    Exp Parasitol 116:205-13. 2007
    ..that allows the exogenous T7RNAP-driven gene expression to be tetracycline-inducible; and may provide a useful tool for addressing protein function by manipulating expression levels of Leishmania endogenous genes...
  10. pmc Internal and surface-localized major surface proteases of Leishmania spp. and their differential release from promastigotes
    Chaoqun Yao
    Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA
    Eukaryot Cell 6:1905-12. 2007
    ..We present a model in which these different MSP pools are released under distinct life cycle-specific conditions...
  11. ncbi Multiple products of the Leishmania chagasi major surface protease (MSP or GP63) gene family
    Chaoqun Yao
    Department of Internal Medicine, University of Iowa, 300L, EMRB, Newton Road, Iowa City, IA 52242, USA Chaoqun
    Mol Biochem Parasitol 135:171-83. 2004
    ..These data demonstrate that the products of individual MSP genes are differentially expressed during Leishmania development. We hypothesize they may play different roles during parasite migration through its two hosts...
  12. ncbi The major surface protease (MSP or GP63) of Leishmania sp. Biosynthesis, regulation of expression, and function
    Chaoqun Yao
    VA Medical Center, University of Iowa, Iowa City, IA 52242, USA
    Mol Biochem Parasitol 132:1-16. 2003
    ..The MSPs exquisitely demonstrate the multiple levels of post-transcriptional gene regulation that occur in Leishmania sp. and other trypanosomatid protozoa...
  13. ncbi Risk factors associated with bovine trichomoniasis in beef cattle identified by a questionnaire
    YinZhu Jin
    Department of Veterinary Sciences and Wyoming State Veterinary Laboratory, University of Wyoming, Laramie, WY 82070, USA
    J Med Microbiol 63:896-902. 2014
    ..078). This study provides producers with valuable information and useful suggestions on how to effectively control and reduce the risks of bovine trichomoniasis...
  14. ncbi Biosynthesis of the major surface protease GP63 of Leishmania chagasi
    Chaoqun Yao
    Department of Internal Medicine, University of Iowa, SW34 GH, 200 Hawkins Dr, Iowa City, IA 52242, USA
    Mol Biochem Parasitol 121:119-28. 2002
    ..The current findings add yet another level of complexity to post-transcriptionally regulated expression of an abundant surface molecule in a trypanosomatid protozoan...