Evangelia Yannaki

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. ncbi request reprint G-CSF-primed hematopoietic stem cells or G-CSF per se accelerate recovery and improve survival after liver injury, predominantly by promoting endogenous repair programs
    Evangelia Yannaki
    Gene and Cell Therapy Center, Hematology Department BMT Unit, G Papanicolaou Hospital, Thessaloniki, Greece
    Exp Hematol 33:108-19. 2005
  2. pmc Hematopoietic stem cell mobilization for gene therapy of adult patients with severe β-thalassemia: results of clinical trials using G-CSF or plerixafor in splenectomized and nonsplenectomized subjects
    Evangelia Yannaki
    Gene and Cell Therapy Center, Hematology Department BMT Unit, George Papanicolaou Hospital, Thessaloniki, Greece
    Mol Ther 20:230-8. 2012
  3. doi request reprint The proteasome inhibitor bortezomib drastically affects inflammation and bone disease in adjuvant-induced arthritis in rats
    Evangelia Yannaki
    George Papanicolaou Hospital, Gene and Cell Therapy Center, Thessaloniki, Greece
    Arthritis Rheum 62:3277-88. 2010
  4. doi request reprint Gene therapy for β-thalassaemia: the continuing challenge
    Evangelia Yannaki
    Gene and Cell Therapy Center, Hematology Department BMT Unit, George Papanicolaou Hospital, Thessaloniki, Greece
    Expert Rev Mol Med 12:e31. 2010
  5. doi request reprint Hematopoietic stem cell mobilization strategies for gene therapy of beta thalassemia and sickle cell disease
    Evangelia Yannaki
    Gene and Cell Therapy Center, Hematology BMT Unit, George Papanicolaou Hospital, Thessaloniki, Greece
    Ann N Y Acad Sci 1202:59-63. 2010
  6. doi request reprint Mobilization of hematopoietic stem cells in a thalassemic mouse model: implications for human gene therapy of thalassemia
    Evangelia Yannaki
    Gene and Cell Therapy Center, Hematology Department BMT Unit, George Papanicolaou Hospital, Thessaloniki 57010, Greece
    Hum Gene Ther 21:299-310. 2010
  7. ncbi request reprint Allografted recipients immunized against hepatitis B virus are at high risk of gradual surface antibody (HbsAb) disappearance post transplant, regardless of adoptive immunity transfer
    Panayotis Kaloyannidis
    Hematology Department, BMT Unit, George Papanicolaou Hospital, Thessaloniki, Greece
    Biol Blood Marrow Transplant 13:1049-56. 2007
  8. ncbi request reprint Lasting amelioration in the clinical course of decompensated alcoholic cirrhosis with boost infusions of mobilized peripheral blood stem cells
    Evangelia Yannaki
    Hematology Department BMT Unit and Gene and Cell Therapy Center, George Papanicolaou Hospital, Thessaloniki, Greece
    Exp Hematol 34:1583-7. 2006
  9. pmc Hematopoietic stem cell mobilization for gene therapy: superior mobilization by the combination of granulocyte-colony stimulating factor plus plerixafor in patients with β-thalassemia major
    Evangelia Yannaki
    1 Hematology BMT Unit, Gene and Cell Therapy Center, George Papanicolaou Hospital, Thessaloniki 57010, Greece
    Hum Gene Ther 24:852-60. 2013
  10. doi request reprint Mesenchymal stem cells are conditionally therapeutic in preclinical models of rheumatoid arthritis
    Anastasia Papadopoulou
    George Papanicolaou Hospital, Gene and Cell Therapy Center, Hematology Department BMT Unit, Thessaloniki 57010, Greece
    Ann Rheum Dis 71:1733-40. 2012

Collaborators

  • Panayotis Kaloyannidis
  • G Stamatoyannopoulos
  • David Emery
  • Pamela Becker
  • Qiliang Li
  • T Papayannopoulou
  • Luanne L Peters
  • KENNETH PETERSON
  • Achilles Anagnostopoulos
  • Eleftheria Tsolaki
  • Anastasia Papadopoulou
  • Ioannis Batsis
  • Ioanna Sakellari
  • Nikolaos Zogas
  • Evangelia Athanasiou
  • Garyfalia Karponi
  • Nikoleta Psatha
  • Minas Yiangou
  • Christos Smias
  • Athanasios Fassas
  • Charalambos Kartsios
  • Conrad Russell Cruz
  • Carsten Werner Lederer
  • Vasiliki Douka
  • Fani Zervou
  • Panayiotis Baliakas
  • Chrysa Apostolou
  • Marina Kleanthous
  • Constantinos Tsatalas
  • Damianos Sotiropoulos
  • Kyriakos Karypidis
  • Eleni Maria Abela
  • Despoina Mallouri
  • Jennifer Eileen Adair
  • Nikoletta Psatha
  • Isabelle Riviere
  • Michalis Iskas
  • Michel Sadelain
  • Giorgos Kouvatseas
  • Varnavas Konstantinou
  • Anastasia Marvaki
  • Varnavas Constantinou
  • Antonios Gkountis
  • Eleni Gounari
  • Panayotis Baliakas
  • Eleni Sgouramali
  • Minas Arsenakis
  • Eleni Siotou
  • Athanasios Siametis
  • Ioannis Georgoulis
  • Vassilios Penopoulos
  • Photios Iordanidis

Detail Information

Publications22

  1. ncbi request reprint G-CSF-primed hematopoietic stem cells or G-CSF per se accelerate recovery and improve survival after liver injury, predominantly by promoting endogenous repair programs
    Evangelia Yannaki
    Gene and Cell Therapy Center, Hematology Department BMT Unit, G Papanicolaou Hospital, Thessaloniki, Greece
    Exp Hematol 33:108-19. 2005
    ..We also examined the origin of cells (endogenous or BM) reconstituting liver after damage...
  2. pmc Hematopoietic stem cell mobilization for gene therapy of adult patients with severe β-thalassemia: results of clinical trials using G-CSF or plerixafor in splenectomized and nonsplenectomized subjects
    Evangelia Yannaki
    Gene and Cell Therapy Center, Hematology Department BMT Unit, George Papanicolaou Hospital, Thessaloniki, Greece
    Mol Ther 20:230-8. 2012
    ..For gene therapy of thalassemia, G-CSF or Plerixafor could be used as mobilization agents in non-SPL patients whereas Plerixafor appears to be the mobilization agent of choice in SPL adult thalassemics in terms of safety and efficacy...
  3. doi request reprint The proteasome inhibitor bortezomib drastically affects inflammation and bone disease in adjuvant-induced arthritis in rats
    Evangelia Yannaki
    George Papanicolaou Hospital, Gene and Cell Therapy Center, Thessaloniki, Greece
    Arthritis Rheum 62:3277-88. 2010
    ..To explore the effect of bortezomib in splenocytes and fibroblast-like synoviocytes (FLS) and its in vivo potency in a rat model of adjuvant-induced arthritis (AIA), which resembles human rheumatoid arthritis (RA)...
  4. doi request reprint Gene therapy for β-thalassaemia: the continuing challenge
    Evangelia Yannaki
    Gene and Cell Therapy Center, Hematology Department BMT Unit, George Papanicolaou Hospital, Thessaloniki, Greece
    Expert Rev Mol Med 12:e31. 2010
    ....
  5. doi request reprint Hematopoietic stem cell mobilization strategies for gene therapy of beta thalassemia and sickle cell disease
    Evangelia Yannaki
    Gene and Cell Therapy Center, Hematology BMT Unit, George Papanicolaou Hospital, Thessaloniki, Greece
    Ann N Y Acad Sci 1202:59-63. 2010
    ....
  6. doi request reprint Mobilization of hematopoietic stem cells in a thalassemic mouse model: implications for human gene therapy of thalassemia
    Evangelia Yannaki
    Gene and Cell Therapy Center, Hematology Department BMT Unit, George Papanicolaou Hospital, Thessaloniki 57010, Greece
    Hum Gene Ther 21:299-310. 2010
    ..In addition, strategies to minimize the risk of G-CSF-induced splenic infarcts should be explored in a clinical setting...
  7. ncbi request reprint Allografted recipients immunized against hepatitis B virus are at high risk of gradual surface antibody (HbsAb) disappearance post transplant, regardless of adoptive immunity transfer
    Panayotis Kaloyannidis
    Hematology Department, BMT Unit, George Papanicolaou Hospital, Thessaloniki, Greece
    Biol Blood Marrow Transplant 13:1049-56. 2007
    ..Allotransplanted patients are at high risk of losing protection against HBV. The adoptive transfer of active HBV immunity does not seem to offer sustained protection posttransplant...
  8. ncbi request reprint Lasting amelioration in the clinical course of decompensated alcoholic cirrhosis with boost infusions of mobilized peripheral blood stem cells
    Evangelia Yannaki
    Hematology Department BMT Unit and Gene and Cell Therapy Center, George Papanicolaou Hospital, Thessaloniki, Greece
    Exp Hematol 34:1583-7. 2006
    ..Additional studies in this area will be required to document efficacy and evaluate toxicity...
  9. pmc Hematopoietic stem cell mobilization for gene therapy: superior mobilization by the combination of granulocyte-colony stimulating factor plus plerixafor in patients with β-thalassemia major
    Evangelia Yannaki
    1 Hematology BMT Unit, Gene and Cell Therapy Center, George Papanicolaou Hospital, Thessaloniki 57010, Greece
    Hum Gene Ther 24:852-60. 2013
    ..The high yields and the favorable transplantation features render the G-CSF+plerixafor-mobilized cells the optimal CD34(+) cell source for stem cell gene therapy applications...
  10. doi request reprint Mesenchymal stem cells are conditionally therapeutic in preclinical models of rheumatoid arthritis
    Anastasia Papadopoulou
    George Papanicolaou Hospital, Gene and Cell Therapy Center, Hematology Department BMT Unit, Thessaloniki 57010, Greece
    Ann Rheum Dis 71:1733-40. 2012
    ..This study explored the effect of bone marrow-derived MSC in previously untested and pathogenetically different models of rheumatoid arthritis (RA)...
  11. ncbi request reprint Veno-occlusive disease prophylaxis with fresh frozen plasma and heparin in bone marrow transplantation
    Ioannis Batsis
    G Papanicolaou Hospital, Hematology Department BMT Unit, Thessaloniki, Greece
    Thromb Res 118:611-8. 2006
    ..In order to evaluate if there truely is a beneficial effect of heparin+FFP in VOD prophylaxis, we have initiated a prospective randomized trial...
  12. doi request reprint The impact of desferrioxamine postallogeneic hematopoietic cell transplantation in relapse incidence and disease-free survival: a retrospective analysis
    Panayotis Kaloyannidis
    Department of Hematology, BMT Unit, George Papanicolaou Hospital, 57010 Exokhi, Thessaloniki, Greece
    Transplantation 89:472-9. 2010
    ..Several clinical and preclinical studies have shown that desferrioxamine (DFO), in addition to iron chelation, demonstrates antiproliferative activities against some aggressive malignancies and leukemic cells...
  13. pmc Superior long-term repopulating capacity of G-CSF+plerixafor-mobilized blood: implications for stem cell gene therapy by studies in the Hbb(th-3) mouse model
    Nikoleta Psatha
    1 Hematology BMT Unit, Gene and Cell Therapy Center, George Papanicolaou Hospital, Thessaloniki 57010, Greece
    Hum Gene Ther Methods 25:317-27. 2014
    ....
  14. doi request reprint Hematopoietic stem cells and liver regeneration: differentially acting hematopoietic stem cell mobilization agents reverse induced chronic liver injury
    Eleftheria Tsolaki
    Gene and Cell Therapy Center, Hematology Department BMT Unit, George Papanicolaou Hospital, Thessaloniki, Greece Department of Genetics, Development and Molecular Biology, School of Biology, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Blood Cells Mol Dis 53:124-32. 2014
    ..Overall, our data suggest that G-CSF, Plerixafor and G-CSF+Plerixafor act differentially during the wound healing process, ultimately providing a potent anti-fibrotic effect. ..
  15. ncbi request reprint Development of virus vectors for gene therapy of beta chain hemoglobinopathies: flanking with a chromatin insulator reduces gamma-globin gene silencing in vivo
    David W Emery
    Department of Medicine, Division of Medical Genetics, Box 357720, HSB K236F, University of Washington, 1705 NE Pacific Street, Seattle, WA 98195 7720, USA
    Blood 100:2012-9. 2002
    ....
  16. pmc Plerixafor+G-CSF-mobilized CD34+ cells represent an optimal graft source for thalassemia gene therapy
    Garyfalia Karponi
    Gene and Cell Therapy Center, Hematology Department Bone Marrow Transplantation Unit, George Papanicolaou Hospital, Thessaloniki, Greece School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece
    Blood 126:616-9. 2015
    ....
  17. ncbi request reprint Topological constraints governing the use of the chicken HS4 chromatin insulator in oncoretrovirus vectors
    Evangelia Yannaki
    Gene and Cell Therapy Center, Hematology Department and Bone Marrow Transplantation Unit, George Papanikolaou General Hospital, Thessaloniki, Greece
    Mol Ther 5:589-98. 2002
    ..These findings have direct implications for the use of chromatin insulators such as cHS4 in oncoretrovirus vectors...
  18. ncbi request reprint Spontaneous adrenal haemorrhage as a manifestation of isolated relapse of non-Hodgkin's lymphoma
    Charalambos Kartsios
    BMT Unit, Haematology Department, G Papanicolaou General Hospital, Thessaloniki, Greece
    Acta Haematol 110:197-9. 2003
    ..Six months later, she was rehospitalized because of abdominal pain; an MRI revealed a large haemorrhagic mass in the left adrenal. Surgical removal of the lesion confirmed an adrenal relapse of the primary DLBCL...
  19. doi request reprint Adoptive transfer of Aspergillus-specific T cells as a novel anti-fungal therapy for hematopoietic stem cell transplant recipients: Progress and challenges
    Anastasia Papadopoulou
    Hematology Department Hematopoietic Cell Transplantation Unit, Gene and Cell Therapy Center, George Papanicolaou Hospital, Thessaloniki, Greece Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece Electronic address
    Crit Rev Oncol Hematol 98:62-72. 2016
    ..This review highlights the recent advances in this field, and discusses critical issues involved in development and protocol design of Asp-ST immunotherapy. ..
  20. doi request reprint Carmustine, etoposide, cytarabine and melphalan versus a newly designed intravenous busulfan-based Busulfex, etoposide and melphalan conditioning regimen for autologous hematopoietic cell transplant: a retrospective matched-pair analysis in advanced Hodgk
    Ioanna Sakellari
    a Hematology Department and BMT Unit, George Papanicolaou Hospital, Thessaloniki, Greece
    Leuk Lymphoma 56:3071-81. 2015
    ..In conclusion, BuEM was well tolerated and equally highly efficacious as BEAM for non-Hodgkin lymphoma and offered marginally significantly improved PFS and OS in HL with acceptable toxicity and zero mortality. ..
  21. doi request reprint Stem cell-based regenerative opportunities for the liver: State of the art and beyond
    Eleftheria Tsolaki
    Eleftheria Tsolaki, Evangelia Yannaki, Gene and Cell Therapy Center, Hematology Department BMT Unit, George Papanicolaou Hospital, 57010 Thessaloniki, Greece
    World J Gastroenterol 21:12334-50. 2015
    ....
  22. ncbi request reprint Transgenic Cre expression mice for generation of erythroid-specific gene alterations
    Kenneth R Peterson
    Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas 66160 7421, USA
    Genesis 39:1-9. 2004
    ..We demonstrate that beta(S) expression was not detected in the blood of bigenics, but the gene was present in nonerythroid cells. Thus, excision of the loxP-flanked beta(S) gene was restricted to erythroid cell lineages...