Zhen YangSummaryAffiliation: University of Houston Country: USA Publications
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Publications
Preparative isolation of bufalin and cinobufagin from Chinese traditional medicine ChanSuZhen Yang
National Pharmaceutical Research Center, Shanghai Institute of Pharmaceutical Industry, Shanghai, PR China
J Chromatogr Sci 46:81-5. 2008..9 and 3.1 g, respectively, from 500 g of ChanSu. These two compounds have been identified by mass spectrometry and 1H NMR, and their purities were quantitated by HPLC at 99% and 98%, respectively...- Palladium-catalyzed carbonylative annulation of o-alkynylphenols: syntheses of 2-substituted-3-aroyl-benzo[b]furansYouhong Hu
Institute of Chemistry and Cell Biology, Harvard Medical School, Boston, Massachusetts 02115 5731, USA
J Org Chem 67:2365-8. 2002..Consistent with this mechanism, addition of 1 equiv of AgBF(4) to palladium catalyst Pd(Ph(3)P)(4) generates an ideal candidate for this unique transformation... 
Stereoselective construction of an unprecedented 7-8 fused ring system in micrandilactone a by [3,3]-sigmatropic rearrangementYan Dong Zhang
Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Shenzhen Graduate School, Peking University, Beijing 100871, China
Org Lett 10:665-8. 2008....- Efficient synthesis of maleimides and carbazoles via Zn(OTf)(2)-catalyzed tandem annulations of isonitriles and allenic estersYuanzhen Li
Laboratory of Chemical Genomics, Shenzhen Graduate School, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Peking University, Beijing 100871, China
Org Lett 9:4057-60. 2007..A mechanistic rationale is proposed to account for the observed reactivity... - An efficient one-pot asymmetric synthesis of biaryl compounds via Diels-Alder/retro-Diels-Alder cascade reactionsYongxiang Liu
Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education and Beijing National Laboratory for Molecular Science BNLMS, College of Chemistry, Laboratory of Chemical Genomics, Shenzhen Graduate School, China
Org Lett 9:805-8. 2007..This methodology should find broad application in the synthesis of natural products and asymmetric catalysts... - Synthetic study of 1,3-butadiene-based IMDA approach to construct a [5-7-6] tricyclic core and its application to the total synthesis of C8-epi-guanacastepene OChuang-Chuang Li
Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Ministry of Education and Beijing National Laboratory for Molecular Science (BNLMS, College of Chemistry, Shenzhen Graduate School, Peking University, Beijing 100871, China
J Org Chem 71:6892-7. 2006..This method facilitates the synthesis of C8-epi-guanacastepene O (36) in a very efficient manner... - Oxidative DNA cleavage promoted by multinuclear copper complexes: activity dependence on the complex structureYongmei Zhao
State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P.R. China
Chemistry 12:6621-9. 2006..This work is a good example of the rational design of multinuclear Cu2+ artificial nuclease and the activity of which can be manipulated by the geometry and the number of metal centers... - Development of a concise and diversity-oriented approach for the synthesis of plecomacrolides via the diene-ene RCMKui Lu
Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Beijing, China
Org Lett 8:1193-6. 2006..This approach should allow access to the structurally diverse analogues of plecomacrolide... - Exploring an expedient IMDA reaction approach to construct the guanacastepene coreChuang-Chuang Li
Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Ministry of Education, College of Chemistry, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Science, Peking University, Beijing 100871, China
Org Lett 7:3709-12. 2005..The illustrated chemistry demonstrated a synthetic feasibility to build up the framework of guanacastepenes by the IMDA reaction. [reaction: see text].. - Pd-catalyzed copper-free carbonylative Sonogashira reaction of aryl iodides with alkynes for the synthesis of alkynyl ketones and flavones by using water as a solventBo Liang
Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Ministry of Education, College of Chemistry, School of Pharmaceutical Science, Shenzhen Graduate School, Peking University, Beijing 100871, China
J Org Chem 70:6097-100. 2005..The reaction was carried out at room temperature under balloon pressure of CO with Et(3)N as a base. The developed method was successfully applied to the synthesis of flavones... - Thioureas as ligands in the pd-catalyzed intramolecular Pauson-Khand reactionYefeng Tang
Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Beijing 100871, China
Org Lett 7:1657-9. 2005.... - A highly efficient synthesis of the FGH ring of micrandilactone A. Application of thioureas as ligands in the Co-catalyzed Pauson-Khand reaction and Pd-catalyzed carbonylative annulationYefeng Tang
Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Beijing 100871, China
Org Lett 7:885-8. 2005..The key reactions in our strategy are the Co-thiourea-catalyzed stereoselective, intramolecular Pauson-Khand reaction and Pd-thiourea-catalyzed stereoselective, intramolecular annulation. [structure: see text].. - Concise synthesis of isoquinoline via the Ugi and Heck reactionsZheng Xiang
Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Beijing, 100871, China
Org Lett 6:3155-8. 2004.... - Synthesis of conformationally restricted 2,3-diarylbenzo[b]furan by the Pd-catalyzed annulation of o-alkynylphenols: exploring a combinatorial approachYouhong Hu
VivoQuest, Inc, 711 Executive Boulevard, Valley Cottage, New York 10989, USA
J Org Chem 69:2235-9. 2004..This method provides an efficient synthetic pathway for the combinatorial synthesis of conformationally restricted 2,3-diarylbenzo[b]furan for drug discovery... - Total synthesis of methyl protodioscin: a potent agent with antitumor activityMao S Cheng
School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, 110016, P R China
J Org Chem 68:3658-62. 2003..8%... - Convergent solid-phase synthesis of symmetrical benzo[b]furan's dimerizerYun Liao
VivoQuest, Inc. 711 Executive Blvd. Valley Cottage, New York 10989, USA
J Comb Chem 5:79-81. 2003 - Total synthesis of crisamicin AZhengtao Li
Laboratory of Chemical Genomics, Shenzhen Graduate School, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Beijing
Org Lett 10:3017-20. 2008....