Zhen Yang

Summary

Affiliation: University of Houston
Country: USA

Publications

  1. ncbi request reprint Preparative isolation of bufalin and cinobufagin from Chinese traditional medicine ChanSu
    Zhen Yang
    National Pharmaceutical Research Center, Shanghai Institute of Pharmaceutical Industry, Shanghai, PR China
    J Chromatogr Sci 46:81-5. 2008
  2. ncbi request reprint Palladium-catalyzed carbonylative annulation of o-alkynylphenols: syntheses of 2-substituted-3-aroyl-benzo[b]furans
    Youhong Hu
    Institute of Chemistry and Cell Biology, Harvard Medical School, Boston, Massachusetts 02115 5731, USA
    J Org Chem 67:2365-8. 2002
  3. doi request reprint Stereoselective construction of an unprecedented 7-8 fused ring system in micrandilactone a by [3,3]-sigmatropic rearrangement
    Yan Dong Zhang
    Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Shenzhen Graduate School, Peking University, Beijing 100871, China
    Org Lett 10:665-8. 2008
  4. ncbi request reprint Efficient synthesis of maleimides and carbazoles via Zn(OTf)(2)-catalyzed tandem annulations of isonitriles and allenic esters
    Yuanzhen Li
    Laboratory of Chemical Genomics, Shenzhen Graduate School, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Peking University, Beijing 100871, China
    Org Lett 9:4057-60. 2007
  5. ncbi request reprint An efficient one-pot asymmetric synthesis of biaryl compounds via Diels-Alder/retro-Diels-Alder cascade reactions
    Yongxiang Liu
    Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education and Beijing National Laboratory for Molecular Science BNLMS, College of Chemistry, Laboratory of Chemical Genomics, Shenzhen Graduate School, China
    Org Lett 9:805-8. 2007
  6. ncbi request reprint Synthetic study of 1,3-butadiene-based IMDA approach to construct a [5-7-6] tricyclic core and its application to the total synthesis of C8-epi-guanacastepene O
    Chuang Chuang Li
    Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Ministry of Education and Beijing National Laboratory for Molecular Science BNLMS, College of Chemistry, Shenzhen Graduate School, Peking University, Beijing 100871, China
    J Org Chem 71:6892-7. 2006
  7. ncbi request reprint Oxidative DNA cleavage promoted by multinuclear copper complexes: activity dependence on the complex structure
    Yongmei Zhao
    State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P R China
    Chemistry 12:6621-9. 2006
  8. ncbi request reprint Development of a concise and diversity-oriented approach for the synthesis of plecomacrolides via the diene-ene RCM
    Kui Lu
    Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Beijing, China
    Org Lett 8:1193-6. 2006
  9. ncbi request reprint Exploring an expedient IMDA reaction approach to construct the guanacastepene core
    Chuang Chuang Li
    Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Ministry of Education, College of Chemistry, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Science, Peking University, Beijing 100871, China
    Org Lett 7:3709-12. 2005
  10. ncbi request reprint Pd-catalyzed copper-free carbonylative Sonogashira reaction of aryl iodides with alkynes for the synthesis of alkynyl ketones and flavones by using water as a solvent
    Bo Liang
    Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Ministry of Education, College of Chemistry, School of Pharmaceutical Science, Shenzhen Graduate School, Peking University, Beijing 100871, China
    J Org Chem 70:6097-100. 2005

Collaborators

  • Jiahua Chen
  • Yefeng Tang
  • Kui Lu
  • Reza Fathi
  • Chuang Chuang Li
  • Youhong Hu
  • Mingji Dai
  • Yongxiang Liu
  • Jia Hua Chen
  • Bo Liang
  • Tuoping Luo
  • Zheng Xiang
  • Yun Liao
  • Zhengtao Li
  • Yan Dong Zhang
  • Guoxin Wang
  • Kai Wang
  • Junmin Quan
  • Yuanzhen Li
  • Yongmei Zhao
  • Yun Dong Wu
  • Xin Hao Zhang
  • Shuang Liang
  • Mengwei Huang
  • Lujiang Deng
  • Mao S Cheng
  • Wei Wu Ren
  • Yingxiang Gao
  • Yu Lan
  • Zhigang Wang
  • Jie Xu
  • Qing Xiao
  • Jing Xiang
  • Jianxian Gong
  • Wanqing Wu
  • Haixia Zou
  • Yangguang Zhu
  • Jianhui Zhu
  • Yizhi Li
  • Weijiang He
  • Lu Jiang Deng
  • Junfeng Zhang
  • Zijian Guo
  • Cui Hua Wang
  • Zhengchang Xiong
  • Guangbin Dong
  • Yandong Zhang
  • Zejin You
  • Zhi Xiang Xie
  • Yangdong Zhang
  • Jian Ma
  • Jiayue Cui
  • Kenneth J Nawoschik
  • Xiaomeng Shi
  • Hong D Miao
  • Xin S Yao
  • Xin Xu
  • Quan Tian
  • Qiang Li
  • Hong Y Song
  • Qian L Wang
  • Yong X Liu
  • Yan Zhang

Detail Information

Publications17

  1. ncbi request reprint Preparative isolation of bufalin and cinobufagin from Chinese traditional medicine ChanSu
    Zhen Yang
    National Pharmaceutical Research Center, Shanghai Institute of Pharmaceutical Industry, Shanghai, PR China
    J Chromatogr Sci 46:81-5. 2008
    ..9 and 3.1 g, respectively, from 500 g of ChanSu. These two compounds have been identified by mass spectrometry and 1H NMR, and their purities were quantitated by HPLC at 99% and 98%, respectively...
  2. ncbi request reprint Palladium-catalyzed carbonylative annulation of o-alkynylphenols: syntheses of 2-substituted-3-aroyl-benzo[b]furans
    Youhong Hu
    Institute of Chemistry and Cell Biology, Harvard Medical School, Boston, Massachusetts 02115 5731, USA
    J Org Chem 67:2365-8. 2002
    ..Consistent with this mechanism, addition of 1 equiv of AgBF(4) to palladium catalyst Pd(Ph(3)P)(4) generates an ideal candidate for this unique transformation...
  3. doi request reprint Stereoselective construction of an unprecedented 7-8 fused ring system in micrandilactone a by [3,3]-sigmatropic rearrangement
    Yan Dong Zhang
    Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Shenzhen Graduate School, Peking University, Beijing 100871, China
    Org Lett 10:665-8. 2008
    ....
  4. ncbi request reprint Efficient synthesis of maleimides and carbazoles via Zn(OTf)(2)-catalyzed tandem annulations of isonitriles and allenic esters
    Yuanzhen Li
    Laboratory of Chemical Genomics, Shenzhen Graduate School, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Peking University, Beijing 100871, China
    Org Lett 9:4057-60. 2007
    ..A mechanistic rationale is proposed to account for the observed reactivity...
  5. ncbi request reprint An efficient one-pot asymmetric synthesis of biaryl compounds via Diels-Alder/retro-Diels-Alder cascade reactions
    Yongxiang Liu
    Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education and Beijing National Laboratory for Molecular Science BNLMS, College of Chemistry, Laboratory of Chemical Genomics, Shenzhen Graduate School, China
    Org Lett 9:805-8. 2007
    ..This methodology should find broad application in the synthesis of natural products and asymmetric catalysts...
  6. ncbi request reprint Synthetic study of 1,3-butadiene-based IMDA approach to construct a [5-7-6] tricyclic core and its application to the total synthesis of C8-epi-guanacastepene O
    Chuang Chuang Li
    Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Ministry of Education and Beijing National Laboratory for Molecular Science BNLMS, College of Chemistry, Shenzhen Graduate School, Peking University, Beijing 100871, China
    J Org Chem 71:6892-7. 2006
    ..This method facilitates the synthesis of C8-epi-guanacastepene O (36) in a very efficient manner...
  7. ncbi request reprint Oxidative DNA cleavage promoted by multinuclear copper complexes: activity dependence on the complex structure
    Yongmei Zhao
    State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P R China
    Chemistry 12:6621-9. 2006
    ..This work is a good example of the rational design of multinuclear Cu2+ artificial nuclease and the activity of which can be manipulated by the geometry and the number of metal centers...
  8. ncbi request reprint Development of a concise and diversity-oriented approach for the synthesis of plecomacrolides via the diene-ene RCM
    Kui Lu
    Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Beijing, China
    Org Lett 8:1193-6. 2006
    ..This approach should allow access to the structurally diverse analogues of plecomacrolide...
  9. ncbi request reprint Exploring an expedient IMDA reaction approach to construct the guanacastepene core
    Chuang Chuang Li
    Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Ministry of Education, College of Chemistry, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Science, Peking University, Beijing 100871, China
    Org Lett 7:3709-12. 2005
    ..The illustrated chemistry demonstrated a synthetic feasibility to build up the framework of guanacastepenes by the IMDA reaction. [reaction: see text]..
  10. ncbi request reprint Pd-catalyzed copper-free carbonylative Sonogashira reaction of aryl iodides with alkynes for the synthesis of alkynyl ketones and flavones by using water as a solvent
    Bo Liang
    Key Laboratory of Bioorganic Chemistry and Molecular Engineering, Ministry of Education, College of Chemistry, School of Pharmaceutical Science, Shenzhen Graduate School, Peking University, Beijing 100871, China
    J Org Chem 70:6097-100. 2005
    ..The reaction was carried out at room temperature under balloon pressure of CO with Et(3)N as a base. The developed method was successfully applied to the synthesis of flavones...
  11. ncbi request reprint Thioureas as ligands in the pd-catalyzed intramolecular Pauson-Khand reaction
    Yefeng Tang
    Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Beijing 100871, China
    Org Lett 7:1657-9. 2005
    ....
  12. ncbi request reprint A highly efficient synthesis of the FGH ring of micrandilactone A. Application of thioureas as ligands in the Co-catalyzed Pauson-Khand reaction and Pd-catalyzed carbonylative annulation
    Yefeng Tang
    Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Beijing 100871, China
    Org Lett 7:885-8. 2005
    ..The key reactions in our strategy are the Co-thiourea-catalyzed stereoselective, intramolecular Pauson-Khand reaction and Pd-thiourea-catalyzed stereoselective, intramolecular annulation. [structure: see text]..
  13. ncbi request reprint Concise synthesis of isoquinoline via the Ugi and Heck reactions
    Zheng Xiang
    Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Beijing, 100871, China
    Org Lett 6:3155-8. 2004
    ....
  14. ncbi request reprint Synthesis of conformationally restricted 2,3-diarylbenzo[b]furan by the Pd-catalyzed annulation of o-alkynylphenols: exploring a combinatorial approach
    Youhong Hu
    VivoQuest, Inc, 711 Executive Boulevard, Valley Cottage, New York 10989, USA
    J Org Chem 69:2235-9. 2004
    ..This method provides an efficient synthetic pathway for the combinatorial synthesis of conformationally restricted 2,3-diarylbenzo[b]furan for drug discovery...
  15. ncbi request reprint Total synthesis of methyl protodioscin: a potent agent with antitumor activity
    Mao S Cheng
    School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, 110016, P R China
    J Org Chem 68:3658-62. 2003
    ..8%...
  16. ncbi request reprint Convergent solid-phase synthesis of symmetrical benzo[b]furan's dimerizer
    Yun Liao
    VivoQuest, Inc 711 Executive Blvd Valley Cottage, New York 10989, USA
    J Comb Chem 5:79-81. 2003
  17. doi request reprint Total synthesis of crisamicin A
    Zhengtao Li
    Laboratory of Chemical Genomics, Shenzhen Graduate School, Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Beijing
    Org Lett 10:3017-20. 2008
    ....