Research Topics
| Yu Xiao YangSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Publications
Chronic proton pump inihibitor therapy and calcium metabolismYu Xiao Yang
Division of Gastroenterology, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Curr Gastroenterol Rep 14:473-9. 2012..Second, profound gastric acid suppression may reduce the bioavailability of calcium for intestinal absorption. I will review the published evidence regarding these potential links and discuss their clinical implications...
Prevention and treatment of stress ulcers in critically ill patientsYu Xiao Yang
Gastroenterology Division, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA
Semin Gastrointest Dis 14:11-9. 2003..More potent acid suppression by proton pump inhibitors may offer additional benefit in the prevention of stress ulcer bleeding...
Serial glycosylated hemoglobin levels and risk of colorectal neoplasia among patients with type 2 diabetes mellitusYu Xiao Yang
Department of Medicine, Division of Gastroenterology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 722 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104, USA
Cancer Epidemiol Biomarkers Prev 19:3027-36. 2010..We sought to determine whether glycemic control measured by serial hemoglobin A1c (HbA1c) was associated with the risk of colorectal adenoma...- Safety of proton pump inhibitor exposureYu Xiao Yang
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Gastroenterology 139:1115-27. 2010..We summarize the data available on the putative adverse effects of PPI therapy and propose guidelines for clinicians who prescribe these agents to limit the potential for adverse outcomes in users of these effective therapeutic agents... - Proton pump inhibitor therapy and osteoporosisYu Xiao Yang
Division of Gastroenterology, Center for Clinical Epidemiology and Biostatistics, and Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Curr Drug Saf 3:204-9. 2008.... - Chronic statin therapy and the risk of colorectal cancerYu Xiao Yang
Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Pharmacoepidemiol Drug Saf 17:869-76. 2008..We sought to clarify whether long-term statin therapy has a chemopreventive effect on the risk of colorectal cancer (CRC) in a large, population-representative cohort... - Chronic proton pump inhibitor therapy and the risk of colorectal cancerYu Xiao Yang
Division of Gastroenterology, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6021, USA
Gastroenterology 133:748-54. 2007.... - Long-term proton pump inhibitor therapy and risk of hip fractureYu Xiao Yang
Division of Gastroenterology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
JAMA 296:2947-53. 2006..Proton pump inhibitors (PPIs) may interfere with calcium absorption through induction of hypochlorhydria but they also may reduce bone resorption through inhibition of osteoclastic vacuolar proton pumps... - Insulin therapy and colorectal cancer risk among type 2 diabetes mellitus patientsYu Xiao Yang
Division of Gastroenterology, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
Gastroenterology 127:1044-50. 2004..We aimed to determine whether insulin therapy might increase the risk of colorectal cancer among type 2 diabetes mellitus patients... - Type 2 diabetes mellitus and the risk of colorectal cancerYu Xiao Yang
Division of Gastroenterology, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Clin Gastroenterol Hepatol 3:587-94. 2005..However, epidemiologic evidence for this association is inconclusive. We conducted a population-based study to clarify this association... - Fibrate/Statin initiation in warfarin users and gastrointestinal bleeding riskHedi Schelleman
Center for Clinical Epidemiology and Biostatistics and Center for Education and Research on Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, USA
Am J Med 123:151-7. 2010..To evaluate whether initiation of a fibrate or statin increases the risk of hospitalization for gastrointestinal bleeding in warfarin users... - Association between model for end-stage liver disease and spontaneous bacterial peritonitisKeith L Obstein
Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Am J Gastroenterol 102:2732-6. 2007..To determine whether a greater Model for End-Stage Liver Disease (MELD) score is associated with a greater risk of spontaneous bacterial peritonitis (SBP)... - Proton-pump inhibitor use and the risk for community-acquired pneumoniaMonika Sarkar
University of Pennsylvania, Philadelphia, Pennsylvania 19104 6021, USA
Ann Intern Med 149:391-8. 2008..Recent studies suggest that proton-pump inhibitors (PPIs) may increase the risk for community-acquired pneumonia (CAP)... - Observed association between antidepressant use and pneumonia risk was confounded by comorbidity measuresSean Hennessy
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
J Clin Epidemiol 60:911-8. 2007..A prior study suggested that antidepressants might increase the risk of hospitalization for pneumonia in the elderly. This study sought to confirm or refute this hypothesis... - Women with a prior diagnosis of breast cancer are not at an increased risk for subsequent colorectal cancerRadhika Srinivasan
Division of Gastroenterology, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6021, USA
Am J Gastroenterol 100:2759-64. 2005..08) and 1.81 (95% CI 0.85-3.85), respectively. CONCLUSION: Women with a prior diagnosis of breast cancer are not at an increased risk of colorectal cancer; these women can follow average risk screening guidelines for colorectal cancer... - Risk of hip fracture associated with hepatitis C virus infection and hepatitis C/human immunodeficiency virus coinfectionVincent Lo Re
Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Hepatology 56:1688-98. 2012..HCV-monoinfected patients had an increased risk of hip fracture, compared to uninfected individuals... - Insulin therapy and colorectal adenomas in patients with diabetes mellitusPatricia Wong
Division of Gastroenterology, Hospital of the University of Pennsylvania, Philadelphia, USA
Cancer Epidemiol Biomarkers Prev 21:1833-40. 2012..The aim of this study was to evaluate the association between exogenous insulin therapy and adenoma formation, accounting for duration of therapy and location and stage of the adenoma... - Risk of colorectal cancer in women with a prior diagnosis of gynecologic malignancyRadhika Srinivasan
Department of Medicine, Division of Gastroenterology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
J Clin Gastroenterol 41:291-6. 2007..Earlier studies regarding the risk of colorectal cancer (CRC) in women with a prior diagnosis of gynecologic malignancies have revealed conflicting results. We sought to further clarify this association... - Hip fracture risk in patients with a diagnosis of pernicious anemiaNathan A Merriman
Division of Gastroenterology, Center for Clinical Epidemiology and Biostatistics, Philadelphia, Pennsylvania 19104 6021, USA
Gastroenterology 138:1330-7. 2010..Pernicious anemia (PA) is characterized by vitamin B-12 deficiency and achlorhydria, both of which have a detrimental effect on bone strength. The principle aim of this study was to determine the risk of hip fracture in patients with PA... - No increased risk of myocardial infarction among patients with ulcerative colitis or Crohn's diseaseMark T Osterman
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Clin Gastroenterol Hepatol 9:875-80. 2011..We aimed to determine the risk of first-time acute MI in patients with ulcerative colitis (UC) or Crohn's disease (CD) compared with patients from general practice... - Findings on serial surveillance colonoscopy in patients with low-risk polyps on initial colonoscopyJocelyne Miller
Division of Gastroenterology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
J Clin Gastroenterol 44:e46-50. 2010..This study describes the prevalence of adenomatous polyps at serial follow-up exams after a colonoscopy finding 1 to 2 small tubular adenomas... - Type 2 diabetes mellitus and survival in pancreatic adenocarcinoma: a retrospective cohort studyAllen Hwang
Department of Gastroenterology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Cancer 119:404-10. 2013..Our aim was to determine the effect of varying durations of pre-existing T2DM on survival in patients with PAC... - Incidence and prevalence of abnormal liver associated enzymes in patients with atrial fibrillation in a routine clinical care populationGeorge A Makar
Division of Gastroenterology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Pharmacoepidemiol Drug Saf 17:43-51. 2008..The aim of this study was to estimate the prevalence and incidence of alanine aminotransferase (ALT) elevations in a cohort with AF... - The effect of a physician-targeted intervention on metoclopramide prescribing practiceYu Xiao Yang
Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA, USA
Ther Clin Risk Manag 7:359-65. 2011..Metoclopramide use is associated with serious and potentially irreversible neurologic side effects. However, it is often used for questionable or unclear indications in clinical practice... - Association between proton pump inhibitor use and spontaneous bacterial peritonitisMical S Campbell
Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Dig Dis Sci 53:394-8. 2008..22 (95% confidence interval: 0.52-2.87) and 1.05 (0.43-2.57), respectively. In conclusion, we did not find a positive association between PPI use and spontaneous bacterial peritonitis... - Risks and benefits of menopausal hormone therapy in postmenopausal Chinese womenIrene H Su
University of California, San Diego, Department of Reproductive Medicine, La Jolla, CA, USA
Menopause 19:931-41. 2012..The aim of this study was to assess risks and benefits of conjugated equine estrogens (CEE) and medroxyprogesterone acetate (MPA) in postmenopausal Chinese women... - Cholecystectomy and the risk of colorectal cancerTheresa Shao
Division of Gastroenterology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Am J Gastroenterol 100:1813-20. 2005..CONCLUSIONS: Cholecystectomy is associated with a modestly increased risk of colon cancer but not for rectal cancer. Lithogenic bile could be the underlying mechanism... - Videofluoroscopic studies of swallowing dysfunction and the relative risk of pneumoniaLana Pikus
Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia 19104, USA
AJR Am J Roentgenol 180:1613-6. 2003..Patients with laryngeal penetration, tracheobronchial aspiration, or silent tracheobronchial aspiration are, in increasing order of magnitude, significantly more likely to develop pneumonia than patients with normal swallowing... - Barrett's esophagus in 2008: an updateRichard K Wood
Division of Gastroenterology, Department of Medicine and Center for Clinical Epidemiology and Biostatistics University of Pennsylvania School of Medicine, Pennsylvania 19104 6021, USA
Keio J Med 57:132-8. 2008..The advent of various endoscopic ablative therapies has provided a promising alternative to surgery for Barrett's patients with high grade dysplasia (HGD)...