Ri Yao Yang

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Galectins in cell growth and apoptosis
    R Y Yang
    Department of Dermatology, UC Davis School of Medicine, 4645 Second Avenue Room 3100C, Sacramento, California 95817, USA
    Cell Mol Life Sci 60:267-76. 2003
  2. ncbi request reprint Galectin-12 is required for adipogenic signaling and adipocyte differentiation
    Ri Yao Yang
    Department of Dermatology, University of California Davis School of Medicine, Sacramento, California 95817, USA
    J Biol Chem 279:29761-6. 2004
  3. pmc Ablation of a galectin preferentially expressed in adipocytes increases lipolysis, reduces adiposity, and improves insulin sensitivity in mice
    Ri Yao Yang
    Department of Dermatology, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA
    Proc Natl Acad Sci U S A 108:18696-701. 2011
  4. pmc Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes keratinocyte migration
    Wei Liu
    Department of Dermatology, University of California, Davis, Davis, California 95816, USA
    J Invest Dermatol 132:2828-37. 2012
  5. ncbi request reprint Roles of galectin-3 in immune responses
    Huan Yuan Chen
    School of Medicine, University of California Davis, 4645 Second Avenue, Sacramento, CA 95817, USA
    Arch Immunol Ther Exp (Warsz) 53:497-504. 2005
  6. doi request reprint Galectins in acute and chronic inflammation
    Fu Tong Liu
    Department of Dermatology, University of California Davis, School of Medicine, Sacramento, 95816, USA
    Ann N Y Acad Sci 1253:80-91. 2012
  7. doi request reprint Galectins: structure, function and therapeutic potential
    Ri Yao Yang
    Department of Dermatology, University of California, Davis, School of Medicine, Sacramento, CA 95816, USA
    Expert Rev Mol Med 10:e17. 2008
  8. ncbi request reprint Galectins in apoptosis
    Daniel K Hsu
    Department of Dermatology, University of California, Davis School of Medicine, Sacramento, California, USA
    Methods Enzymol 417:256-73. 2006
  9. pmc Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse
    Huan Yuan Chen
    Department of Dermatology, School of Medicine, University of California at Davis, Sacramento, CA 95817, USA
    Proc Natl Acad Sci U S A 106:14496-501. 2009
  10. ncbi request reprint Galectin-7 (PIG1) exhibits pro-apoptotic function through JNK activation and mitochondrial cytochrome c release
    Ichiro Kuwabara
    Divisions of Allergy and Cellular Immunology, La Jolla Institute for Allergy and Immunology, San Diego, California 92121, USA
    J Biol Chem 277:3487-97. 2002

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Galectins in cell growth and apoptosis
    R Y Yang
    Department of Dermatology, UC Davis School of Medicine, 4645 Second Avenue Room 3100C, Sacramento, California 95817, USA
    Cell Mol Life Sci 60:267-76. 2003
    ..Galectin-3 is the only member known so far to inhibit apoptosis, while galectin-1, -7 and -9 promote this cellular process. Galectins can act either extracellularly or intracellularly to exert effects on cell growth and apoptosis...
  2. ncbi request reprint Galectin-12 is required for adipogenic signaling and adipocyte differentiation
    Ri Yao Yang
    Department of Dermatology, University of California Davis School of Medicine, Sacramento, California 95817, USA
    J Biol Chem 279:29761-6. 2004
    ..The findings suggest that galectin-12 is a major regulator of adipose tissue development...
  3. pmc Ablation of a galectin preferentially expressed in adipocytes increases lipolysis, reduces adiposity, and improves insulin sensitivity in mice
    Ri Yao Yang
    Department of Dermatology, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA
    Proc Natl Acad Sci U S A 108:18696-701. 2011
    ..These findings add to the significant functions exhibited by intracellular galectins, and have important therapeutic implications for human metabolic disorders...
  4. pmc Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes keratinocyte migration
    Wei Liu
    Department of Dermatology, University of California, Davis, Davis, California 95816, USA
    J Invest Dermatol 132:2828-37. 2012
    ..Our results suggest that galectin-3 is potentially a critical regulator of a number of important cellular responses through its intracellular control of trafficking of cell surface receptors...
  5. ncbi request reprint Roles of galectin-3 in immune responses
    Huan Yuan Chen
    School of Medicine, University of California Davis, 4645 Second Avenue, Sacramento, CA 95817, USA
    Arch Immunol Ther Exp (Warsz) 53:497-504. 2005
    ..This review summarizes the roles of galectin-3 in the immune system and discusses the possible underlying mechanisms...
  6. doi request reprint Galectins in acute and chronic inflammation
    Fu Tong Liu
    Department of Dermatology, University of California Davis, School of Medicine, Sacramento, 95816, USA
    Ann N Y Acad Sci 1253:80-91. 2012
    ..Current evidence also suggests that galectins may be therapeutic targets or employed as therapeutic agents for these inflammatory responses...
  7. doi request reprint Galectins: structure, function and therapeutic potential
    Ri Yao Yang
    Department of Dermatology, University of California, Davis, School of Medicine, Sacramento, CA 95816, USA
    Expert Rev Mol Med 10:e17. 2008
    ..Thus, galectins may be a therapeutic target or employed as therapeutic agents for inflammatory diseases, cancers and several other diseases...
  8. ncbi request reprint Galectins in apoptosis
    Daniel K Hsu
    Department of Dermatology, University of California, Davis School of Medicine, Sacramento, California, USA
    Methods Enzymol 417:256-73. 2006
    ..This review describes involvement of galectin-1, -2, -3, -7, -8, -9, and -12 in apoptosis...
  9. pmc Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse
    Huan Yuan Chen
    Department of Dermatology, School of Medicine, University of California at Davis, Sacramento, CA 95817, USA
    Proc Natl Acad Sci U S A 106:14496-501. 2009
    ..We conclude that galectin-3 is an inhibitory regulator of T-cell activation and functions intracellularly by promoting TCR down-regulation, possibly through modulating Alix's function at the IS...
  10. ncbi request reprint Galectin-7 (PIG1) exhibits pro-apoptotic function through JNK activation and mitochondrial cytochrome c release
    Ichiro Kuwabara
    Divisions of Allergy and Cellular Immunology, La Jolla Institute for Allergy and Immunology, San Diego, California 92121, USA
    J Biol Chem 277:3487-97. 2002
    ..Some of them are potentially contributory to this lectin's proapoptotic function and these include redox-related genes monoamine oxidase B, ryanodine receptor 2, and glutathione S-transferase Mu 3...