Hongmei Yang

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Statistical estimation & inference of cell counts from ELISPOT limiting dilution assays
    Hongmei Yang
    Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Biopharm Stat 23:921-36. 2013
  2. pmc B cell responses to H5 influenza HA in human subjects vaccinated with a drifted variant
    Jane Baer
    David H Smith Center for Vaccine Biology and Immunology, Aab Institute for Biomedical Sciences, Department of Microbiology and Immunology, Rochester, NY, USA
    Vaccine 28:907-15. 2010
  3. pmc High-resolution temporal response patterns to influenza vaccine reveal a distinct human plasma cell gene signature
    Alicia D Henn
    Department of Medicine, Division of Nephrology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Sci Rep 3:2327. 2013
  4. pmc Increase in IFNγ(-)IL-2(+) cells in recent human CD4 T cell responses to 2009 pandemic H1N1 influenza
    Jason M Weaver
    David H Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS ONE 8:e57275. 2013
  5. pmc Host differences in influenza-specific CD4 T cell and B cell responses are modulated by viral strain and route of immunization
    Aarthi Sundararajan
    David H Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS ONE 7:e34377. 2012
  6. pmc B cell response and hemagglutinin stalk-reactive antibody production in different age cohorts following 2009 H1N1 influenza virus vaccination
    Mark Y Sangster
    David H Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, USA
    Clin Vaccine Immunol 20:867-76. 2013
  7. pmc CD4+ T-cell expansion predicts neutralizing antibody responses to monovalent, inactivated 2009 pandemic influenza A(H1N1) virus subtype H1N1 vaccine
    Jennifer L Nayak
    Department of Pediatrics, Department of Pediatrics, Division of Infectious Diseases, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Infect Dis 207:297-305. 2013
  8. doi request reprint Frequencies of human influenza-specific antibody secreting cells or plasmablasts post vaccination from fresh and frozen peripheral blood mononuclear cells
    Shuya Y Kyu
    Division of Pulmonary and Critical Care Medicine, NY 14642, USA
    J Immunol Methods 340:42-7. 2009
  9. pmc Anergic responses characterize a large fraction of human autoreactive naive B cells expressing low levels of surface IgM
    Tâm D Quách
    Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Immunol 186:4640-8. 2011

Collaborators

Detail Information

Publications9

  1. pmc Statistical estimation & inference of cell counts from ELISPOT limiting dilution assays
    Hongmei Yang
    Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Biopharm Stat 23:921-36. 2013
    ..Thus, the t -test or the Wilcoxon Rank Sum test can be applied to detect group differences. These methods are compared through simulations and application to real data. ..
  2. pmc B cell responses to H5 influenza HA in human subjects vaccinated with a drifted variant
    Jane Baer
    David H Smith Center for Vaccine Biology and Immunology, Aab Institute for Biomedical Sciences, Department of Microbiology and Immunology, Rochester, NY, USA
    Vaccine 28:907-15. 2010
    ..These observations suggest prior vaccination against H5 influenza HA induces cellular immune responses that cross-react among drifted variants, without precluding a response to new, or existing HA strains...
  3. pmc High-resolution temporal response patterns to influenza vaccine reveal a distinct human plasma cell gene signature
    Alicia D Henn
    Department of Medicine, Division of Nephrology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Sci Rep 3:2327. 2013
    ..With robust statistical methods, time-varying response characteristics of individual subjects were effectively captured along with a shared plasma cell gene signature. ..
  4. pmc Increase in IFNγ(-)IL-2(+) cells in recent human CD4 T cell responses to 2009 pandemic H1N1 influenza
    Jason M Weaver
    David H Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS ONE 8:e57275. 2013
    ....
  5. pmc Host differences in influenza-specific CD4 T cell and B cell responses are modulated by viral strain and route of immunization
    Aarthi Sundararajan
    David H Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS ONE 7:e34377. 2012
    ..Our findings emphasize the importance of immunization strategy for demonstrating inherent host differences in CD4 T cell and B cell responses...
  6. pmc B cell response and hemagglutinin stalk-reactive antibody production in different age cohorts following 2009 H1N1 influenza virus vaccination
    Mark Y Sangster
    David H Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, USA
    Clin Vaccine Immunol 20:867-76. 2013
    ..They also emphasize the need to clarify how the level of circulating stalk-reactive Abs relates to resistance to influenza...
  7. pmc CD4+ T-cell expansion predicts neutralizing antibody responses to monovalent, inactivated 2009 pandemic influenza A(H1N1) virus subtype H1N1 vaccine
    Jennifer L Nayak
    Department of Pediatrics, Department of Pediatrics, Division of Infectious Diseases, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Infect Dis 207:297-305. 2013
    ....
  8. doi request reprint Frequencies of human influenza-specific antibody secreting cells or plasmablasts post vaccination from fresh and frozen peripheral blood mononuclear cells
    Shuya Y Kyu
    Division of Pulmonary and Critical Care Medicine, NY 14642, USA
    J Immunol Methods 340:42-7. 2009
    ..43, 0.28, 0.28 respectively). These results demonstrate feasibility of testing whether antigen-specific ASC from frozen PBMC are an early biomarker of long-term antibody responses in multi-center vaccine trials...
  9. pmc Anergic responses characterize a large fraction of human autoreactive naive B cells expressing low levels of surface IgM
    Tâm D Quách
    Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Immunol 186:4640-8. 2011
    ....