Dun Yang

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells
    Dun Yang
    G W Hooper Foundation and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143 0552, USA
    Proc Natl Acad Sci U S A 99:9942-7. 2002
  2. pmc Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA
    Federico Calegari
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauer Strasse 108, 01307 Dresden, Germany
    Proc Natl Acad Sci U S A 99:14236-40. 2002
  3. ncbi request reprint RNA interference (RNAi) with RNase III-prepared siRNAs
    Dun Yang
    G W Hooper Foundation, Department of Microbiology and Immunology, University of California, San Francisco, USA
    Methods Mol Biol 252:471-82. 2004
  4. pmc Cell division and cell survival in the absence of survivin
    Dun Yang
    G W Hooper Research Foundation and Department of Microbiology and Immunology, University of California, 513 Parnassus Avenue, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:15100-5. 2004
  5. ncbi request reprint Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC
    Andrei Goga
    Department of Medicine, Division of Hematology Oncology, University of California, San Francisco, San Francisco, California 94143 0552, USA
    Nat Med 13:820-7. 2007
  6. pmc Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase
    Dun Yang
    Department of Microbiology and Immunology, G W Hooper Research Foundation, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 107:13836-41. 2010
  7. pmc MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits
    Hong Liu
    G W Hooper Foundation, University of California at San Francisco, San Francisco, California 94143, USA
    Nat Cell Biol 14:567-74. 2012

Collaborators

Detail Information

Publications7

  1. pmc Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells
    Dun Yang
    G W Hooper Foundation and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143 0552, USA
    Proc Natl Acad Sci U S A 99:9942-7. 2002
    ..esiRNA works by eliciting the destruction of its cognate mRNA. Because of its simplicity and potency, this approach is useful for analysis of mammalian gene functions...
  2. pmc Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA
    Federico Calegari
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauer Strasse 108, 01307 Dresden, Germany
    Proc Natl Acad Sci U S A 99:14236-40. 2002
    ..Taken together, our data indicate that esiRNA delivered in a tissue-specific manner by topical injection followed by directed electroporation can efficiently silence endogenous gene expression in mammalian postimplantation embryos...
  3. ncbi request reprint RNA interference (RNAi) with RNase III-prepared siRNAs
    Dun Yang
    G W Hooper Foundation, Department of Microbiology and Immunology, University of California, San Francisco, USA
    Methods Mol Biol 252:471-82. 2004
    ..Since the whole gene can be used at once, screening for an active siRNA for an individual gene is eliminated. Because of its simplicity and potency, this approach is useful for large-scale analysis of mammalian gene function...
  4. pmc Cell division and cell survival in the absence of survivin
    Dun Yang
    G W Hooper Research Foundation and Department of Microbiology and Immunology, University of California, 513 Parnassus Avenue, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:15100-5. 2004
    ..However, the protein is not inevitably required for the survival of normal cells...
  5. ncbi request reprint Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC
    Andrei Goga
    Department of Medicine, Division of Hematology Oncology, University of California, San Francisco, San Francisco, California 94143 0552, USA
    Nat Med 13:820-7. 2007
    ..As there are no effective small-molecule inhibitors that selectively target the MYC pathway, we propose that CDK1 inhibition might therefore be useful in the treatment of human malignancies that overexpress MYC...
  6. pmc Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase
    Dun Yang
    Department of Microbiology and Immunology, G W Hooper Research Foundation, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 107:13836-41. 2010
    ....
  7. pmc MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits
    Hong Liu
    G W Hooper Foundation, University of California at San Francisco, San Francisco, California 94143, USA
    Nat Cell Biol 14:567-74. 2012
    ....