Q S Yan

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. ncbi request reprint RNA interference-mediated inhibition of brain-derived neurotrophic factor expression increases cocaine's cytotoxicity in cultured cells
    Qing Shan Yan
    Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine at Peoria, Peoria, IL 61656, USA
    Neurosci Lett 414:165-9. 2007
  2. ncbi request reprint Involvement of 5-HT1B receptors within the ventral tegmental area in ethanol-induced increases in mesolimbic dopaminergic transmission
    Qing Shan Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Peoria, IL 61656, USA
    Brain Res 1060:126-37. 2005
  3. ncbi request reprint Different expression of brain-derived neurotrophic factor in the nucleus accumbens of alcohol-preferring (P) and -nonpreferring (NP) rats
    Qing Shan Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, Peoria, IL 61656, USA
    Brain Res 1035:215-8. 2005
  4. ncbi request reprint Involvement of 5-HT1B receptors within the ventral tegmental area in regulation of mesolimbic dopaminergic neuronal activity via GABA mechanisms: a study with dual-probe microdialysis
    Qing Shan Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, Peoria, IL 61656, USA
    Brain Res 1021:82-91. 2004
  5. ncbi request reprint Prenatal cocaine exposure decreases brain-derived neurotrophic factor proteins in the rat brain
    Qing Shan Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Peoria, IL 61656, USA
    Brain Res 1009:228-33. 2004
  6. ncbi request reprint Involvement of non-exocytotic mechanisms in ethanol-induced in vivo dopamine release: comparisons with cocaine
    Qing Shan Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, Peoria, IL 61656, USA
    Eur J Pharmacol 477:37-44. 2003
  7. ncbi request reprint Ethanol-induced, nonexocytotic [3H]dopamine release from rat nucleus accumbens slices
    Qing Shan Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, Peoria, IL 61656, USA
    Alcohol 27:127-34. 2002
  8. ncbi request reprint Reduced serotonin release and serotonin uptake sites in the rat nucleus accumbens and striatum after prenatal cocaine exposure
    Qing Shan Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Peoria, IL 61656, USA
    Brain Res 929:59-69. 2002
  9. ncbi request reprint Serotonin-1B receptor-mediated inhibition of [(3)H]GABA release from rat ventral tegmental area slices
    Q S Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Peoria, Illinois 61656, USA
    J Neurochem 79:914-22. 2001
  10. ncbi request reprint Activation of 5-HT(1B/1D) receptors in the mesolimbic dopamine system increases dopamine release from the nucleus accumbens: a microdialysis study
    Q S Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, 61656, USA
    Eur J Pharmacol 418:55-64. 2001

Research Grants

Collaborators

Detail Information

Publications21

  1. ncbi request reprint RNA interference-mediated inhibition of brain-derived neurotrophic factor expression increases cocaine's cytotoxicity in cultured cells
    Qing Shan Yan
    Department of Cancer Biology and Pharmacology, University of Illinois College of Medicine at Peoria, Peoria, IL 61656, USA
    Neurosci Lett 414:165-9. 2007
    ....
  2. ncbi request reprint Involvement of 5-HT1B receptors within the ventral tegmental area in ethanol-induced increases in mesolimbic dopaminergic transmission
    Qing Shan Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Peoria, IL 61656, USA
    Brain Res 1060:126-37. 2005
    ....
  3. ncbi request reprint Different expression of brain-derived neurotrophic factor in the nucleus accumbens of alcohol-preferring (P) and -nonpreferring (NP) rats
    Qing Shan Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, Peoria, IL 61656, USA
    Brain Res 1035:215-8. 2005
    ....
  4. ncbi request reprint Involvement of 5-HT1B receptors within the ventral tegmental area in regulation of mesolimbic dopaminergic neuronal activity via GABA mechanisms: a study with dual-probe microdialysis
    Qing Shan Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, Peoria, IL 61656, USA
    Brain Res 1021:82-91. 2004
    ..The increased DA neuron activity may be associated, at least in part, with the 5-HT1B receptor-mediated inhibition of VTA GABA release...
  5. ncbi request reprint Prenatal cocaine exposure decreases brain-derived neurotrophic factor proteins in the rat brain
    Qing Shan Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Peoria, IL 61656, USA
    Brain Res 1009:228-33. 2004
    ..The results support the suggestion that prenatal cocaine exposure decreases BDNF expression in the offspring...
  6. ncbi request reprint Involvement of non-exocytotic mechanisms in ethanol-induced in vivo dopamine release: comparisons with cocaine
    Qing Shan Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, Peoria, IL 61656, USA
    Eur J Pharmacol 477:37-44. 2003
    ....
  7. ncbi request reprint Ethanol-induced, nonexocytotic [3H]dopamine release from rat nucleus accumbens slices
    Qing Shan Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, Peoria, IL 61656, USA
    Alcohol 27:127-34. 2002
    ....
  8. ncbi request reprint Reduced serotonin release and serotonin uptake sites in the rat nucleus accumbens and striatum after prenatal cocaine exposure
    Qing Shan Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Peoria, IL 61656, USA
    Brain Res 929:59-69. 2002
    ....
  9. ncbi request reprint Serotonin-1B receptor-mediated inhibition of [(3)H]GABA release from rat ventral tegmental area slices
    Q S Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Peoria, Illinois 61656, USA
    J Neurochem 79:914-22. 2001
    ..Pre-treatment with SB 216641 also antagonized CP 93129-induced inhibition of [(3)H]GABA release. The results support the hypothesis that 5-HT(1B) receptors within the VTA can function as heteroreceptors to inhibit GABA release...
  10. ncbi request reprint Activation of 5-HT(1B/1D) receptors in the mesolimbic dopamine system increases dopamine release from the nucleus accumbens: a microdialysis study
    Q S Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, 61656, USA
    Eur J Pharmacol 418:55-64. 2001
    ....
  11. ncbi request reprint Enhanced accumbal dopamine release following 5-HT(2A) receptor stimulation in rats pretreated with intermittent cocaine
    Q Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Peoria, IL, USA
    Brain Res 863:254-8. 2000
    ..The results are consistent with the concept that intermittent cocaine may cause enhanced sensitivity of 5-HT(2A) receptors within the NACC...
  12. ncbi request reprint Anticonvulsant effect of enhancement of noradrenergic transmission in the superior colliculus in genetically epilepsy-prone rats (GEPRs): a microinjection study
    Q S Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, IL 61656, USA
    Brain Res 780:199-209. 1998
    ..These results suggest that noradrenergic transmission in the SC may be involved in the seizure regulation in GEPR-9s, and that this regulation may be mediated, at least in part, through alpha 1 receptors...
  13. ncbi request reprint Effect of systemic ethanol on basal and stimulated glutamate releases in the nucleus accumbens of freely moving Sprague-Dawley rats: a microdialysis study
    Q S Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria 61656, USA
    Neurosci Lett 258:29-32. 1998
    ..The present results suggest that EOH may suppress glutamatergic transmission in the NACC by lowering presynaptic GLU release...
  14. ncbi request reprint Extracellular dopamine and serotonin after ethanol monitored with 5-minute microdialysis
    Q S Yan
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, IL 61656, USA
    Alcohol 19:1-7. 1999
    ..In addition, the present data are not in opposition with a role of 5-HT in the ethanol reinforcing effect...
  15. ncbi request reprint Focal bicuculline increases extracellular dopamine concentration in the nucleus accumbens of freely moving rats as measured by in vivo microdialysis
    Q Yan
    Department of Biochemical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, 61656, USA
    Eur J Pharmacol 385:7-13. 1999
    ....
  16. ncbi request reprint Activation of 5-HT2A/2C receptors within the nucleus accumbens increases local dopaminergic transmission
    Q S Yan
    Department of Biochemical and Therapeutic Sciences, University of Illinois College of Medicine, Peoria 61656, USA
    Brain Res Bull 51:75-81. 2000
    ....
  17. ncbi request reprint Extracellular dopamine, norepinephrine, and serotonin in the ventral tegmental area and nucleus accumbens of freely moving rats during intracerebral dialysis following systemic administration of cocaine and other uptake blockers
    M E Reith
    Department of Biomedical and Therapeutic Sciences, University of Illinois, College of Medicine, Peoria 61656, USA
    Psychopharmacology (Berl) 134:309-17. 1997
    ..There is considerable crosstalk between monoamine systems occurring upon systemic administration of uptake blockers, and the VTA and NACC are notably different in the time course of the DA effect (long-lasting versus transient)...
  18. ncbi request reprint Carbamazepine increases extracellular serotonin concentration: lack of antagonism by tetrodotoxin or zero Ca2+
    J W Dailey
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, 61656, USA
    Eur J Pharmacol 328:153-62. 1997
    ..Further they suggest that the effect is mediated by an action of carbamazepine directly on serotonergic nerve terminals...
  19. ncbi request reprint Anticonvulsant doses of carbamazepine increase hippocampal extracellular serotonin in genetically epilepsy-prone rats: dose response relationships
    J W Dailey
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, 61656, USA
    Neurosci Lett 227:13-6. 1997
    ..This result provides further support for the hypothesis that release of serotonin by carbamazepine is an important part of the pharmacodynamic action by which this drug suppresses seizures...
  20. ncbi request reprint Cocaine exposure at a sublethal concentration downregulates CREB functions in cultured neuroblastoma cells
    Mei Jiang Feng
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, Peoria, IL 61656, USA
    Brain Res 1077:59-66. 2006
    ....
  21. ncbi request reprint Effects of prenatal alcohol exposure on brain-derived neurotrophic factor and its receptor tyrosine kinase B in offspring
    Mei Jiang Feng
    Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine at Peoria, Peoria, IL 61656, USA
    Brain Res 1042:125-32. 2005
    ..These alterations in BDNF function may contribute to the development of alcohol-related birth defects...

Research Grants5

  1. ALCOHOL AND MESOLIMBIC DOPAMINE PATHWAY
    QINGSHAN YAN; Fiscal Year: 2002
    ..This will elucidate the relative contribution of 5-HT2 receptors to the regulation of ethanol-induced DA release and help to explain the effects of 5-HT2 antagonists on alcohol consumption reported in the literature. ..
  2. RNAi-medicated inhibition of BDNF expression and alcohol-drinking behavior
    QINGSHAN YAN; Fiscal Year: 2007
    ....