Yukiko Yamashita


Affiliation: University of Michigan
Country: USA


  1. Yamashita Y. A tale of mother and daughter. Mol Biol Cell. 2010;21:7-8 pubmed publisher
    ..When I started, there was a big gap between my love for science and my experience as a scientist. I filled this gap by learning a "laid-back confidence." ..
  2. Jagannathan M, Yamashita Y. Evolution Repeats Itself in Building a Species Barrier. Dev Cell. 2018;47:527-528 pubmed publisher
    ..Recent work shows that uniparental chromosome elimination in hybrids between two frog species triggers a metabolic crisis and embryonic lethality. ..
  3. Venkei Z, Yamashita Y. Emerging mechanisms of asymmetric stem cell division. J Cell Biol. 2018;217:3785-3795 pubmed publisher
    ..In this review, we summarize recent progress in understanding the mechanisms and regulations of asymmetric stem cell division. ..
  4. Yamashita Y, Inaba M, Buszczak M. Specialized Intercellular Communications via Cytonemes and Nanotubes. Annu Rev Cell Dev Biol. 2018;34:59-84 pubmed publisher
    ..Here we review our current understanding of protrusion-based intercellular communication. ..
  5. Yang H, Yamashita Y. The regulated elimination of transit-amplifying cells preserves tissue homeostasis during protein starvation in Drosophila testis. Development. 2015;142:1756-66 pubmed publisher
    ..We propose that the regulated elimination of transit-amplifying cells is essential to preserve stem cell function and tissue homeostasis during protein starvation. ..
  6. Yamashita Y. Biased DNA segregation in Drosophila male germline stem cells. Semin Cell Dev Biol. 2013;24:618-26 pubmed publisher
    ..We will discuss the implications of this observation and molecular mechanisms, which might be applicable to non-random sister chromatid segregation in other systems as well. ..
  7. Yamashita Y. Subcellular Specialization and Organelle Behavior in Germ Cells. Genetics. 2018;208:19-51 pubmed publisher
    ..These germ cell-specific functions of organelles serve critical roles in successful gamete production. In this chapter, I will review the behaviors and roles of organelles during germ cell differentiation. ..
  8. Yamashita Y. Cell adhesion in regulation of asymmetric stem cell division. Curr Opin Cell Biol. 2010;22:605-10 pubmed publisher
    ..Here, I review the recent discovery that cell adhesion molecules govern the behavior of stem cells. ..
  9. Yamashita Y, Mahowald A, Perlin J, Fuller M. Asymmetric inheritance of mother versus daughter centrosome in stem cell division. Science. 2007;315:518-21 pubmed
    ..The mother centrosome remains anchored near the niche while the daughter centrosome migrates to the opposite side of the cell before spindle formation. ..

More Information


  1. Yamashita Y, Fuller M. Asymmetric centrosome behavior and the mechanisms of stem cell division. J Cell Biol. 2008;180:261-6 pubmed publisher
    ..Rev. Genet. 8:462-472). These findings provide new insights and suggest intriguing new models for how cells coordinate spindle orientation with their cellular microenvironment to regulate and direct cell fate decisions within tissues. ..
  2. Buszczak M, Inaba M, Yamashita Y. Signaling by Cellular Protrusions: Keeping the Conversation Private. Trends Cell Biol. 2016;26:526-534 pubmed publisher
    ..Here, we focus on new roles for cellular protrusions in cell-to-cell communication, drawing special attention to how stem cells use specialized extensions to promote reception of self-renewing signals emanating from the niche. ..
  3. Chen C, Fingerhut J, Yamashita Y. The ins(ide) and outs(ide) of asymmetric stem cell division. Curr Opin Cell Biol. 2016;43:1-6 pubmed publisher
    ..In this review, we discuss newly discovered aspects of asymmetric stem cell division that, in concert with well-established mechanisms, contribute to balancing self-renewal and differentiation. ..
  4. Jagannathan M, Warsinger Pepe N, Watase G, Yamashita Y. Comparative Analysis of Satellite DNA in the Drosophila melanogaster Species Complex. G3 (Bethesda). 2017;7:693-704 pubmed publisher
    ..simulans clade (D. simulans, D. mauritiana, and D. sechellia), and suggests the presence of unidentified satellite sequences in these species. ..
  5. Inaba M, Sorenson D, Kortus M, Salzmann V, Yamashita Y. Merlin is required for coordinating proliferation of two stem cell lineages in the Drosophila testis. Sci Rep. 2017;7:2502 pubmed publisher
  6. Lu K, Jensen L, Lei L, Yamashita Y. Stay Connected: A Germ Cell Strategy. Trends Genet. 2017;33:971-978 pubmed publisher
    ..In this review, we summarize current knowledge on the formation of intercellular connectivity, and discuss its meaning by visiting multiple examples of germ cell connectivity observed in evolutionarily distant species. ..