Dhiraj Yadav

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi Pancreatitis: prevalence and risk factors among male veterans in a detoxification program
    Dhiraj Yadav
    Division of Gastroenterology and Hepatology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Pancreas 34:390-8. 2007
  2. ncbi Alcohol-associated pancreatitis
    Dhiraj Yadav
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Gastroenterol Clin North Am 36:219-38, vii. 2007
  3. ncbi Trends in the epidemiology of the first attack of acute pancreatitis: a systematic review
    Dhiraj Yadav
    Division of Gastroenterology and Hepatology, John L McClellan Memorial Veterans Hospital and University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Pancreas 33:323-30. 2006
  4. pmc ABO blood group and chronic pancreatitis risk in the NAPS2 cohort
    Julia B Greer
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Pancreas 40:1188-94. 2011
  5. pmc Are genetic variants in the platelet-derived growth factor [beta] gene associated with chronic pancreatitis?
    Venkata Muddana
    Division of Gastroenterology, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Pancreas 39:1215-9. 2010
  6. ncbi Calcifying obstructive pancreatitis: a study of intraductal papillary mucinous neoplasm associated with pancreatic calcification
    Mauricio Zapiach
    Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, Rochester, Minnesota 55905, USA
    Clin Gastroenterol Hepatol 2:57-63. 2004
  7. pmc Multicenter approach to recurrent acute and chronic pancreatitis in the United States: the North American Pancreatitis Study 2 (NAPS2)
    David C Whitcomb
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Pancreatology 8:520-31. 2008
  8. pmc The epidemiology of pancreatitis and pancreatic cancer
    Dhiraj Yadav
    Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Gastroenterology 144:1252-61. 2013
  9. doi Comparison of existing clinical scoring systems to predict persistent organ failure in patients with acute pancreatitis
    Rawad Mounzer
    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Gastroenterology 142:1476-82; quiz e15-6. 2012
  10. pmc Fibrosis reduces severity of acute-on-chronic pancreatitis in humans
    Chathur Acharya
    Department of Medicine, University of Pittsburgh Medical Center Passavant, Pittsburgh, Pennsylvania, USA
    Gastroenterology 145:466-75. 2013

Detail Information

Publications49

  1. ncbi Pancreatitis: prevalence and risk factors among male veterans in a detoxification program
    Dhiraj Yadav
    Division of Gastroenterology and Hepatology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Pancreas 34:390-8. 2007
    ..To determine the prevalence of pancreatitis and associated risk factors among heavy-drinking veterans...
  2. ncbi Alcohol-associated pancreatitis
    Dhiraj Yadav
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Gastroenterol Clin North Am 36:219-38, vii. 2007
    ..Newer developments in the understanding of complex disorders allow clinicians to understand better the role of cofactors and interactions between known and yet unknown environmental and genetic factors in causing alcoholic pancreatitis...
  3. ncbi Trends in the epidemiology of the first attack of acute pancreatitis: a systematic review
    Dhiraj Yadav
    Division of Gastroenterology and Hepatology, John L McClellan Memorial Veterans Hospital and University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Pancreas 33:323-30. 2006
    ..To systematically review trends in the epidemiology of the first attack of acute pancreatitis (AP) based on reported population-based studies...
  4. pmc ABO blood group and chronic pancreatitis risk in the NAPS2 cohort
    Julia B Greer
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Pancreas 40:1188-94. 2011
    ..Our goal was to determine whether ABO blood group may affect the risk of chronic pancreatitis...
  5. pmc Are genetic variants in the platelet-derived growth factor [beta] gene associated with chronic pancreatitis?
    Venkata Muddana
    Division of Gastroenterology, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Pancreas 39:1215-9. 2010
    ..We also tested the hypothesis that PDGF-[beta] polymorphisms in combination with environmental risk factors such as alcohol and smoking are associated with CP...
  6. ncbi Calcifying obstructive pancreatitis: a study of intraductal papillary mucinous neoplasm associated with pancreatic calcification
    Mauricio Zapiach
    Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, Rochester, Minnesota 55905, USA
    Clin Gastroenterol Hepatol 2:57-63. 2004
    ..The aim of this study is to describe the profile of IPMN associated with calcification and gain insights into the pathogenesis of calcification in IPMN...
  7. pmc Multicenter approach to recurrent acute and chronic pancreatitis in the United States: the North American Pancreatitis Study 2 (NAPS2)
    David C Whitcomb
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Pancreatology 8:520-31. 2008
    ..We developed the North American Pancreatitis Study 2 (NAPS2) to be sufficiently powered to understand the complex environmental, metabolic and genetic mechanisms underlying RAP and CP...
  8. pmc The epidemiology of pancreatitis and pancreatic cancer
    Dhiraj Yadav
    Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Gastroenterology 144:1252-61. 2013
    ..Alcohol abstinence and smoking cessation can alter the progression of pancreatitis and reduce recurrence; smoking cessation is the most effective strategy to reduce the risk of pancreatic cancer...
  9. doi Comparison of existing clinical scoring systems to predict persistent organ failure in patients with acute pancreatitis
    Rawad Mounzer
    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Gastroenterology 142:1476-82; quiz e15-6. 2012
    ..We head-to-head compared the accuracy of these systems in predicting persistent organ failure, developed rules that combined these scores to optimize predictive accuracy, and validated our findings in an independent cohort...
  10. pmc Fibrosis reduces severity of acute-on-chronic pancreatitis in humans
    Chathur Acharya
    Department of Medicine, University of Pittsburgh Medical Center Passavant, Pittsburgh, Pennsylvania, USA
    Gastroenterology 145:466-75. 2013
    ..The amount of intrapancreatic fat (IPF) is increased in obese patients and fibrosis is increased in patients with CP, so we studied whether fibrosis or fat regulate severity of AP attacks in patients with CP...
  11. pmc Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis
    David C Whitcomb
    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Nat Genet 44:1349-54. 2012
    ..These results could partially explain the high frequency of alcohol-related pancreatitis in men (male hemizygote frequency is 0.26, whereas female homozygote frequency is 0.07)...
  12. pmc Smoking is underrecognized as a risk factor for chronic pancreatitis
    Dhiraj Yadav
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Pancreatology 10:713-9. 2010
    ..Smoking is an established risk factor for chronic pancreatitis (CP). We sought to identify how often and in which CP patients physicians consider smoking to be a risk factor...
  13. doi Incidence, prevalence, and survival of chronic pancreatitis: a population-based study
    Dhiraj Yadav
    Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pennsylvania 15213, USA
    Am J Gastroenterol 106:2192-9. 2011
    ..Population-based data on chronic pancreatitis (CP) in the United States are scarce. We determined incidence, prevalence, and survival of CP in Olmsted County, MN...
  14. pmc Alcohol and smoking as risk factors in an epidemiology study of patients with chronic pancreatitis
    Gregory A Cote
    Department of Medicine, Division of Gastroenterology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Clin Gastroenterol Hepatol 9:266-73; quiz e27. 2011
    ..We investigated the epidemiology of alcohol-related CP at tertiary US referral centers...
  15. doi Recent advances in the epidemiology of alcoholic pancreatitis
    Dhiraj Yadav
    Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, 200 Lothrop Street, M2, C Wing, Pittsburgh, PA 15213, USA
    Curr Gastroenterol Rep 13:157-65. 2011
    ..Efforts are needed to increase awareness of the impact of alcohol consumption and smoking on risk for pancreatitis and the benefits of cessation for primary and secondary prevention...
  16. pmc Acute lipotoxicity regulates severity of biliary acute pancreatitis without affecting its initiation
    Chandra Durgampudi
    Department of Medicine, University of Pittsburgh Medical Center Pasavant, Pittsburgh, Pennsylvania
    Am J Pathol 184:1773-84. 2014
    ..Inhibition of lipolysis reduces UFA generation and improves these outcomes of AP without interfering with its induction. ..
  17. doi Revised Atlanta and determinant-based classification: application in a prospective cohort of acute pancreatitis patients
    Haq Nawaz
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Am J Gastroenterol 108:1911-7. 2013
    ....
  18. doi Alcohol consumption, cigarette smoking, and the risk of recurrent acute and chronic pancreatitis
    Dhiraj Yadav
    Department of Medicine, University of Pittsburgh, 3708 Fifth Ave, Pittsburgh, PA 15213, USA
    Arch Intern Med 169:1035-45. 2009
    ..We examined the current prevalence of alcohol use and smoking and their association with RAP and CP in patients evaluated at US referral centers...
  19. ncbi Risk and markers of severe acute pancreatitis
    Georgios I Papachristou
    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Gastroenterol Clin North Am 36:277-96, viii. 2007
    ....
  20. ncbi Portosplenomesenteric venous thrombosis in patients with acute pancreatitis is associated with pancreatic necrosis and usually has a benign course
    Jeffrey Easler
    Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
    Clin Gastroenterol Hepatol 12:854-62. 2014
    ..We evaluated the prevalence and natural history of PSMVT in a well-defined cohort of individuals with AP...
  21. ncbi Spectrum of use and effectiveness of endoscopic and surgical therapies for chronic pancreatitis in the United States
    Lisa M Glass
    From the Section of Gastroenterology and Hepatology, Dartmouth Hitchcock Medical Center, Lebanon, NH Department of Medicine, University of Pittsburgh, Pittsburgh, PA Digestive Disease Center, Medical University of South Carolina, Charleston, SC University of Michigan, Ann Arbor, MI Division of Gastroenterology, Brigham and Women s Hospital, Boston, MA Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL Department of Medicine, Wake Forest University Medical Center, Winston Salem, NC Department of Medicine, Indiana University Medical Center, Indianapolis, IN Department of Internal Medicine, St Louis University School of Medicine, St Louis, MO North Mississippi Medical Center, Tupelo, MS Monterey Gastroenterology, Monterey, CA and Department of Medicine, University of Florida, Gainesville, FL
    Pancreas 43:539-43. 2014
    ..This study aims to describe the frequency of use and reported effectiveness of endoscopic and surgical therapies in patients with chronic pancreatitis treated at US referral centers...
  22. pmc Endoscopic therapy is effective for patients with chronic pancreatitis
    Bridger Clarke
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Clin Gastroenterol Hepatol 10:795-802. 2012
    ..We evaluated use and long-term effectiveness of ET in a well-defined cohort of patients with CP...
  23. doi Natural history following the first attack of acute pancreatitis
    Dhiraj Yadav
    Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Am J Gastroenterol 107:1096-103. 2012
    ..The objective of this study was to determine the risk of recurrent AP (RAP) and subsequent chronic pancreatitis (CP) diagnosis after the first attack of AP...
  24. doi Pain and opioid use in chronic pancreatitis
    Salman Nusrat
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Pancreas 41:264-70. 2012
    ..Opioid therapy for pain in chronic pancreatitis (CP) is associated with tolerance and possibly opioid-induced hyperalgesia. We thus examined opioid use and pain rating in CP patients...
  25. pmc Hospitalizations for chronic pancreatitis in Allegheny County, Pennsylvania, USA
    Dhiraj Yadav
    University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Pancreatology 11:546-52. 2011
    ..Population-based estimates for chronic pancreatitis (CP) are scarce. We determined incident CP hospitalization rates and the risk of pancreatitis-related readmissions in Allegheny County, Pennsylvania, USA...
  26. doi The role of alcohol and smoking in pancreatitis
    Dhiraj Yadav
    Department of Medicine, University of Pittsburgh, Room 401 4, 3708 Fifth Avenue, Pittsburgh, PA 15213, USA
    Nat Rev Gastroenterol Hepatol 7:131-45. 2010
    ..In humans, aggressive interventional counseling against alcohol use may reduce the frequency of recurrent attacks of disease and smoking cessation may help to slow the progression of acute to chronic pancreatitis...
  27. doi Comparison of BISAP, Ranson's, APACHE-II, and CTSI scores in predicting organ failure, complications, and mortality in acute pancreatitis
    Georgios I Papachristou
    Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Am J Gastroenterol 105:435-41; quiz 442. 2010
    ....
  28. doi Evaluation and management of autoimmune pancreatitis: experience at a large US center
    Amit Raina
    Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Am J Gastroenterol 104:2295-306. 2009
    ..Systematic evaluation and management of AIP in the United States is reported only from one center. Our aim was to review the evaluation and management of AIP at a large tertiary center...
  29. doi Mucosal IgG4 cell infiltration in ulcerative colitis is linked to disease activity and primary sclerosing cholangitis
    Amit Raina
    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Inflamm Bowel Dis 19:1232-7. 2013
    ..We systematically evaluated IgG4 cell distribution in colonic mucosal biopsies of patients with IBD and correlated histological findings with disease pattern and mucosal inflammation...
  30. pmc Analyses of hospital administrative data that use diagnosis codes overestimate the cases of acute pancreatitis
    Shreyas Saligram
    Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Clin Gastroenterol Hepatol 10:805-811.e1. 2012
    ..We sought to determine if discharge diagnosis codes accurately identify patients whose clinical course met the standard for AP diagnosis...
  31. ncbi Membranous nephropathy: a rare renal manifestation of IgG4-related systemic disease
    Nidhi Jindal
    University of Pittsburgh, Department of Medicine, Pittsburgh, PA, USA
    Clin Nephrol 77:321-8. 2012
    ..Therefore, clinicians must have a high index of suspicion to make an early diagnosis of ISD in order to initiate appropriate treatment...
  32. doi Type of pain, pain-associated complications, quality of life, disability and resource utilisation in chronic pancreatitis: a prospective cohort study
    Daniel K Mullady
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Gut 60:77-84. 2011
    ..To compare patients with chronic pancreatitis (CP) with constant pain patterns to patients with CP with intermittent pain patterns...
  33. pmc Combined bicarbonate conductance-impairing variants in CFTR and SPINK1 variants are associated with chronic pancreatitis in patients without cystic fibrosis
    Alexander Schneider
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Gastroenterology 140:162-71. 2011
    ..We investigated whether sequence variants in the gene encoding the pancreatic secretory trypsin inhibitor SPINK1 further increase the risk of pancreatitis in these patients...
  34. pmc Risk factors for frequent readmissions and barriers to transplantation in patients with cirrhosis
    Swaytha Ganesh
    Department of Medicine, Division of Gastroenterology, Hepatology, and Nutrition, University of Pittsburgh, Pittsburgh, PA, USA
    PLoS ONE 8:e55140. 2013
    ..The goal of this study was to determine risk factors for frequent readmissions among patients with cirrhosis and identify barriers to transplantation in this population...
  35. ncbi Abdominal compartment syndrome is an early, lethal complication of acute pancreatitis
    Brian Boone
    Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Am Surg 79:601-7. 2013
    ..Prompt recognition and decompressive laparotomy may rescue some of these patients and does not mandate future d├ębridement...
  36. ncbi Beta-cell function and insulin resistance evaluated by HOMA in pancreatic cancer subjects with varying degrees of glucose intolerance
    Suresh T Chari
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA
    Pancreatology 5:229-33. 2005
    ..To gain insights into pathogenesis of pancreatic cancer-associated diabetes...
  37. ncbi Autoimmune pancreatitis
    Alyssa M Krasinskas
    Department of Pathology, University of Pittsburgh, UPMC Presbyterian, 200 Lothrop Street, A610, Pittsburgh, PA 15213, USA
    Gastroenterol Clin North Am 36:239-57, vii. 2007
    ..The treatment of choice for AIP is steroid therapy. Diagnostic criteria for AIP have been proposed that incorporate histologic, radiographic, serologic, and clinical information...
  38. doi Electronic clinical challenges and images in GI. Ileal diverticulitis
    Amit Raina
    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Gastroenterology 134:e5-7. 2008
  39. doi Relationship of serum pancreatic enzyme testing trends with the diagnosis of acute pancreatitis
    Dhiraj Yadav
    Division of Gastroenterology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Pancreas 40:383-9. 2011
    ..The reasons for increasing incidence of acute pancreatitis (AP) are not completely understood. We hypothesized that the rate of serum pancreatic enzyme (PE) testing is increasing, and it correlates with AP diagnosis...
  40. pmc Physicians infrequently adhere to hepatitis vaccination guidelines for chronic liver disease
    Kavitha Thudi
    Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    PLoS ONE 8:e71124. 2013
    ..We determined HAV and HBV vaccination rates in a tertiary care referral hepatology clinic and the impact of electronic health record (EHR)-based reminders on adherence to vaccination guidelines...
  41. pmc Recurrent blood eosinophilia in ulcerative colitis is associated with severe disease and primary sclerosing cholangitis
    Arthur Barrie
    Division of Gastroenterology, Hepatology, and Nutrition, University of Pittsburgh School of Medicine, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Dig Dis Sci 58:222-8. 2013
    ..A subset of IBD patients develops blood eosinophilia, and the clinical profile of these patients is undefined. We sought to characterize IBD patients with and without eosinophilia...
  42. pmc Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis
    Phil A Hart
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA
    Gut 62:1771-6. 2013
    ....
  43. pmc Lipotoxicity causes multisystem organ failure and exacerbates acute pancreatitis in obesity
    Sarah Navina
    Department of Pathology, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Sci Transl Med 3:107ra110. 2011
    ..Thus, therapeutic approaches that target unsaturated fatty acid-mediated lipotoxicity may reduce adverse outcomes in obese patients with critical illnesses such as severe acute pancreatitis...
  44. ncbi Idiopathic tumefactive chronic pancreatitis: clinical profile, histology, and natural history after resection
    Dhiraj Yadav
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA
    Clin Gastroenterol Hepatol 1:129-35. 2003
    ..Little is known about subjects with idiopathic tumefactive chronic pancreatitis (TCP), that is, chronic pancreatitis whose clinical presentation, usually with a mass or obstructive jaundice, suggests cancer...
  45. ncbi Study of recurrence after surgical resection of intraductal papillary mucinous neoplasm of the pancreas
    Suresh T Chari
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Gastroenterology 123:1500-7. 2002
    ....
  46. ncbi Issues in hyperlipidemic pancreatitis
    Dhiraj Yadav
    Our Lady of Mercy University Medical Center, New York Medical College, Bronx, New York 10466, USA
    J Clin Gastroenterol 36:54-62. 2003
    ..The mainstay of treatment includes dietary restriction of fat and lipid-lowering medications (mainly fibric acid derivatives). Experiences with plasmapheresis, lipid pheresis, and extracorporeal lipid elimination are limited...
  47. ncbi A critical evaluation of laboratory tests in acute pancreatitis
    Dhiraj Yadav
    Department of Surgery, Our Lady of Mercy University Medical Center, New York Medical College, Bronx 10466, USA
    Am J Gastroenterol 97:1309-18. 2002
    ..Urinary trypsinogen activation peptides within 12-24 h of onset of AP are able to predict the severity but are not widely available. Serum interleukins 6 and 8 seem promising but remain experimental...
  48. ncbi Idiopathic chronic pancreatitis with periductal lymphoplasmacytic infiltration: clinicopathologic features of 35 cases
    Kenji Notohara
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 27:1119-27. 2003
    ..One of these, lymphoplasmacytic sclerosing pancreatitis, is a histologically unique lesion and could be a pancreatic manifestation of idiopathic fibrosclerosing disorders...
  49. ncbi Autoimmune pancreatitis
    Amit Raina
    N Engl J Med 356:1587; author reply 1587. 2007