Research Topics
Species | Dhiraj YadavSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Detail Information
Publications
Pancreatitis: prevalence and risk factors among male veterans in a detoxification programDhiraj Yadav
Division of Gastroenterology and Hepatology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA
Pancreas 34:390-8. 2007..To determine the prevalence of pancreatitis and associated risk factors among heavy-drinking veterans...- Trends in the epidemiology of the first attack of acute pancreatitis: a systematic reviewDhiraj Yadav
Division of Gastroenterology and Hepatology, John L McClellan Memorial Veterans Hospital and University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
Pancreas 33:323-30. 2006..To systematically review trends in the epidemiology of the first attack of acute pancreatitis (AP) based on reported population-based studies... - Alcohol-associated pancreatitisDhiraj Yadav
Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Gastroenterol Clin North Am 36:219-38, vii. 2007..Newer developments in the understanding of complex disorders allow clinicians to understand better the role of cofactors and interactions between known and yet unknown environmental and genetic factors in causing alcoholic pancreatitis... 
ABO blood group and chronic pancreatitis risk in the NAPS2 cohortJulia B Greer
Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
Pancreas 40:1188-94. 2011..Our goal was to determine whether ABO blood group may affect the risk of chronic pancreatitis...- Are genetic variants in the platelet-derived growth factor [beta] gene associated with chronic pancreatitis?Venkata Muddana
Division of Gastroenterology, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Pancreas 39:1215-9. 2010..We also tested the hypothesis that PDGF-[beta] polymorphisms in combination with environmental risk factors such as alcohol and smoking are associated with CP... - Multicenter approach to recurrent acute and chronic pancreatitis in the United States: the North American Pancreatitis Study 2 (NAPS2)David C Whitcomb
Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Pancreatology 8:520-31. 2008..We developed the North American Pancreatitis Study 2 (NAPS2) to be sufficiently powered to understand the complex environmental, metabolic and genetic mechanisms underlying RAP and CP... - Calcifying obstructive pancreatitis: a study of intraductal papillary mucinous neoplasm associated with pancreatic calcificationMauricio Zapiach
Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, Rochester, Minnesota 55905, USA
Clin Gastroenterol Hepatol 2:57-63. 2004.... 
Comparison of existing clinical scoring systems to predict persistent organ failure in patients with acute pancreatitisRawad Mounzer
Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Gastroenterology 142:1476-82; quiz e15-6. 2012..We head-to-head compared the accuracy of these systems in predicting persistent organ failure, developed rules that combined these scores to optimize predictive accuracy, and validated our findings in an independent cohort...- Smoking is underrecognized as a risk factor for chronic pancreatitisDhiraj Yadav
Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Pancreatology 10:713-9. 2010..Smoking is an established risk factor for chronic pancreatitis (CP). We sought to identify how often and in which CP patients physicians consider smoking to be a risk factor... - Incidence, prevalence, and survival of chronic pancreatitis: a population-based studyDhiraj Yadav
Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pennsylvania 15213, USA
Am J Gastroenterol 106:2192-9. 2011..Population-based data on chronic pancreatitis (CP) in the United States are scarce. We determined incidence, prevalence, and survival of CP in Olmsted County, MN... - Recent advances in the epidemiology of alcoholic pancreatitisDhiraj Yadav
Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, 200 Lothrop Street, M2, C Wing, Pittsburgh, PA 15213, USA
Curr Gastroenterol Rep 13:157-65. 2011..Efforts are needed to increase awareness of the impact of alcohol consumption and smoking on risk for pancreatitis and the benefits of cessation for primary and secondary prevention... - Alcohol and smoking as risk factors in an epidemiology study of patients with chronic pancreatitisGregory A Cote
Department of Medicine, Division of Gastroenterology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
Clin Gastroenterol Hepatol 9:266-73; quiz e27. 2011..We investigated the epidemiology of alcohol-related CP at tertiary US referral centers... - Alcohol consumption, cigarette smoking, and the risk of recurrent acute and chronic pancreatitisDhiraj Yadav
Department of Medicine, University of Pittsburgh, 3708 Fifth Ave, Pittsburgh, PA 15213, USA
Arch Intern Med 169:1035-45. 2009..We examined the current prevalence of alcohol use and smoking and their association with RAP and CP in patients evaluated at US referral centers... - Risk and markers of severe acute pancreatitisGeorgios I Papachristou
Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Gastroenterol Clin North Am 36:277-96, viii. 2007.... - Endoscopic therapy is effective for patients with chronic pancreatitisBridger Clarke
Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Clin Gastroenterol Hepatol 10:795-802. 2012..We evaluated use and long-term effectiveness of ET in a well-defined cohort of patients with CP... - Natural history following the first attack of acute pancreatitisDhiraj Yadav
Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Am J Gastroenterol 107:1096-103. 2012..The objective of this study was to determine the risk of recurrent AP (RAP) and subsequent chronic pancreatitis (CP) diagnosis after the first attack of AP... - Hospitalizations for chronic pancreatitis in Allegheny County, Pennsylvania, USADhiraj Yadav
University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Pancreatology 11:546-52. 2011..Population-based estimates for chronic pancreatitis (CP) are scarce. We determined incident CP hospitalization rates and the risk of pancreatitis-related readmissions in Allegheny County, Pennsylvania, USA... - Pain and opioid use in chronic pancreatitisSalman Nusrat
University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Pancreas 41:264-70. 2012..Opioid therapy for pain in chronic pancreatitis (CP) is associated with tolerance and possibly opioid-induced hyperalgesia. We thus examined opioid use and pain rating in CP patients... - The role of alcohol and smoking in pancreatitisDhiraj Yadav
Department of Medicine, University of Pittsburgh, Room 401 4, 3708 Fifth Avenue, Pittsburgh, PA 15213, USA
Nat Rev Gastroenterol Hepatol 7:131-45. 2010..In humans, aggressive interventional counseling against alcohol use may reduce the frequency of recurrent attacks of disease and smoking cessation may help to slow the progression of acute to chronic pancreatitis... - Comparison of BISAP, Ranson's, APACHE-II, and CTSI scores in predicting organ failure, complications, and mortality in acute pancreatitisGeorgios I Papachristou
Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Am J Gastroenterol 105:435-41; quiz 442. 2010.... - Evaluation and management of autoimmune pancreatitis: experience at a large US centerAmit Raina
Division of Gastroenterology and Hepatology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Am J Gastroenterol 104:2295-306. 2009..Systematic evaluation and management of AIP in the United States is reported only from one center. Our aim was to review the evaluation and management of AIP at a large tertiary center... - Analyses of hospital administrative data that use diagnosis codes overestimate the cases of acute pancreatitisShreyas Saligram
Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Clin Gastroenterol Hepatol 10:805-811.e1. 2012..We sought to determine if discharge diagnosis codes accurately identify patients whose clinical course met the standard for AP diagnosis... - Membranous nephropathy: a rare renal manifestation of IgG4-related systemic diseaseNidhi Jindal
University of Pittsburgh, Department of Medicine, Pittsburgh, PA, USA
Clin Nephrol 77:321-8. 2012..Therefore, clinicians must have a high index of suspicion to make an early diagnosis of ISD in order to initiate appropriate treatment... - Combined bicarbonate conductance-impairing variants in CFTR and SPINK1 variants are associated with chronic pancreatitis in patients without cystic fibrosisAlexander Schneider
Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Gastroenterology 140:162-71. 2011..We investigated whether sequence variants in the gene encoding the pancreatic secretory trypsin inhibitor SPINK1 further increase the risk of pancreatitis in these patients... - Type of pain, pain-associated complications, quality of life, disability and resource utilisation in chronic pancreatitis: a prospective cohort studyDaniel K Mullady
Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Gut 60:77-84. 2011..To compare patients with chronic pancreatitis (CP) with constant pain patterns to patients with CP with intermittent pain patterns... - Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitisDavid C Whitcomb
Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Nat Genet 44:1349-54. 2012..These results could partially explain the high frequency of alcohol-related pancreatitis in men (male hemizygote frequency is 0.26, whereas female homozygote frequency is 0.07)... - Relationship of serum pancreatic enzyme testing trends with the diagnosis of acute pancreatitisDhiraj Yadav
Division of Gastroenterology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Pancreas 40:383-9. 2011..The reasons for increasing incidence of acute pancreatitis (AP) are not completely understood. We hypothesized that the rate of serum pancreatic enzyme (PE) testing is increasing, and it correlates with AP diagnosis... - Beta-cell function and insulin resistance evaluated by HOMA in pancreatic cancer subjects with varying degrees of glucose intoleranceSuresh T Chari
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA
Pancreatology 5:229-33. 2005..To gain insights into pathogenesis of pancreatic cancer-associated diabetes... - Autoimmune pancreatitisAlyssa M Krasinskas
Department of Pathology, University of Pittsburgh, UPMC Presbyterian, 200 Lothrop Street, A610, Pittsburgh, PA 15213, USA
Gastroenterol Clin North Am 36:239-57, vii. 2007..The treatment of choice for AIP is steroid therapy. Diagnostic criteria for AIP have been proposed that incorporate histologic, radiographic, serologic, and clinical information... - Electronic clinical challenges and images in GI. Ileal diverticulitisAmit Raina
Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Gastroenterology 134:e5-7. 2008 - Lipotoxicity causes multisystem organ failure and exacerbates acute pancreatitis in obesitySarah Navina
Department of Pathology, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213, USA
Sci Transl Med 3:107ra110. 2011..Thus, therapeutic approaches that target unsaturated fatty acid-mediated lipotoxicity may reduce adverse outcomes in obese patients with critical illnesses such as severe acute pancreatitis... - Idiopathic tumefactive chronic pancreatitis: clinical profile, histology, and natural history after resectionDhiraj Yadav
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA
Clin Gastroenterol Hepatol 1:129-35. 2003..Resection of mass prevents recurrence of symptoms in idiopathic TCP... - Study of recurrence after surgical resection of intraductal papillary mucinous neoplasm of the pancreasSuresh T Chari
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA
Gastroenterology 123:1500-7. 2002.... - Issues in hyperlipidemic pancreatitisDhiraj Yadav
Our Lady of Mercy University Medical Center, New York Medical College, Bronx, New York 10466, USA
J Clin Gastroenterol 36:54-62. 2003..The mainstay of treatment includes dietary restriction of fat and lipid-lowering medications (mainly fibric acid derivatives). Experiences with plasmapheresis, lipid pheresis, and extracorporeal lipid elimination are limited... - Autoimmune pancreatitisAmit Raina
N Engl J Med 356:1587; author reply 1587. 2007 - Idiopathic chronic pancreatitis with periductal lymphoplasmacytic infiltration: clinicopathologic features of 35 casesKenji Notohara
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
Am J Surg Pathol 27:1119-27. 2003..One of these, lymphoplasmacytic sclerosing pancreatitis, is a histologically unique lesion and could be a pancreatic manifestation of idiopathic fibrosclerosing disorders... - A critical evaluation of laboratory tests in acute pancreatitisDhiraj Yadav
Department of Surgery, Our Lady of Mercy University Medical Center, New York Medical College, Bronx 10466, USA
Am J Gastroenterol 97:1309-18. 2002..Urinary trypsinogen activation peptides within 12-24 h of onset of AP are able to predict the severity but are not widely available. Serum interleukins 6 and 8 seem promising but remain experimental...