Research Topics
Species | Yin XuSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Detail Information
Publications
Progression of chronic myeloid leukemia to blast crisis during treatment with imatinib mesylateYin Xu
Department of Pathology and Laboratory Medicine, University of Minnesota School of Medicine, Minneapolis, USA
Arch Pathol Lab Med 128:980-5. 2004..In addition to disease refractoriness, rare instances of disease progression from chronic phase to blast crisis during imatinib therapy have recently been anecdotally reported...- The t(14;18) in diffuse large B-cell lymphoma: correlation with germinal center-associated markers and clinical featuresYin Xu
Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
Appl Immunohistochem Mol Morphol 13:116-23. 2005..15 of 34; P = 0.09), but no association with bcl-2 expression, CD10, clinical stage, complete remission, or survival. Among nodal or high-stage (III-IV) DLBCL, cases with the t(14;18) showed a trend toward decreased survival (P = 0.12)... - Differential usefulness of various markers in the flow cytometric detection of paroxysmal nocturnal hemoglobinuria in blood and bone marrowHoratiu Olteanu
Department of Pathology, University of Texas, Southwestern Medical Center, Dallas, TX 75390-9073, USA
Am J Clin Pathol 126:781-8. 2006.... - Comparison of immunophenotypes of small B-cell neoplasms in primary lymph node and concurrent blood or marrow samplesYin Xu
Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75390-9073, USA
Am J Clin Pathol 118:758-64. 2002..The remaining major and minor variations would not have affected interpretation... - Immunophenotypic differentiation between neoplastic plasma cells in mature B-cell lymphoma vs plasma cell myelomaAdam C Seegmiller
Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9072, USA
Am J Clin Pathol 127:176-81. 2007..However, some extramedullary plasmacytomas showed lymphoma-like phenotypes, suggesting that, in reality, they may represent non-Hodgkin lymphomas with extensive plasmacytic differentiation... 
Overexpression of CD7 in classical Hodgkin lymphoma-infiltrating T lymphocytesAdam C Seegmiller
Department of Pathology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 9072, USA
Cytometry B Clin Cytom 76:169-74. 2009..However, HL-infiltrating T cells have been shown to play a role in HL pathogenesis. This study characterizes the FC immunophenotype of these T lymphocytes to determine whether they can be used to assist in the diagnosis of HL...- Comparison of multiparameter flow cytometry with cluster analysis and immunohistochemistry for the detection of CD10 in diffuse large B-Cell lymphomasYin Xu
Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9073, USA
Mod Pathol 15:413-9. 2002..Our results indicate 75% sensitivity and 100% specificity of CD10 expression by IHC compared with multiparameter FC with cluster analysis and a 6% technical failure rate... - An extranodal nasal natural killer/T-cell lymphoma with isochromosome 7q10 as the sole cytogenetic aberration was initially diagnosed via bone marrow biopsyHuan You Wang
Department of Pathology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 9073, USA
Arch Pathol Lab Med 131:1709-14. 2007..To our knowledge, this is the first report demonstrating i(7)(q10) as a primary cytogenetic abnormality in an extranodal nasal natural killer cell lymphoma... - Flow cytometric analysis of monocytes as a tool for distinguishing chronic myelomonocytic leukemia from reactive monocytosisYin Xu
Department of Pathology, University of Texas, Southwestern Medical Center, Dallas, TX 75390-9072, USA
Am J Clin Pathol 124:799-806. 2005..007). A combination of monocytosis with 2 or more immunophenotypic aberrancies with 20% or more of marrow monocytes showing moderate CD14 expression was 67% sensitive and 100% specific for CMML... - Composite angioimmunoblastic T-cell lymphoma and diffuse large B-cell lymphoma: a case report and review of the literatureYin Xu
Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75390-9073, USA
Am J Clin Pathol 118:848-54. 2002..Ourfindings raise the possibility that the EBV-associated large B-cell lymphoma is a secondary event in AILT via EBV infection or reactivation followed by clonal expansion of an immortalized EBV-infected B cell clone... - Assessment of CD10 in the diagnosis of small B-cell lymphomas: a multiparameter flow cytometric studyYin Xu
Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75390-9073, USA
Am J Clin Pathol 117:291-300. 2002.... - Diagnostic significance of detecting dysgranulopoiesis in chronic myeloid leukemiaYin Xu
Dept of Laboratory Medicine and Pathology, University of Minnesota Medical School, Mayo Mail Code 609, 420 Delaware St SE, Minneapolis, MN 55455-0374, USA
Am J Clin Pathol 120:778-84. 2003..001). Our findings demonstrated that dysgranulopoiesis was associated strongly with chromosome 17p abnormalities and may indicate the onset of or impending disease transformation... - Cross-linking of CD40 using anti-CD40 antibody, 5C11, has different effects on XG2 multiple myeloma cellsChun-Jian Qi
Jiangsu Key Laboratory of Clinical Immunology, Institute of Biotechnology, Soochow University, 48 Renmin Road, Suzhou 215007, PR China
Immunol Lett 93:151-8. 2004..Autocrine or paracrine induction of IL-6, and up-regulation of membrane TNF and phosphorylation of TNFR1 may partially explain the contradictory biological effects of CD40 cross-linking on XG2 by anti-CD40 mAb... 
Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesionsJuliet A Williams
Curis Incorporated, 61 Moulton Street, Cambridge, MA 02138, USA
Proc Natl Acad Sci U S A 100:4616-21. 2003..These findings directly demonstrate that the use of Hh inhibitors could be a valid therapeutic approach for treating BCC...- Inhibition of overactivated p38 MAPK can restore hematopoiesis in myelodysplastic syndrome progenitorsTony A Navas
Albert Einstein College of Medicine, Bronx, NY, USA
Blood 108:4170-7. 2006..These data implicate p38 MAPK in the pathobiology of ineffective hematopoiesis in lowrisk MDS and provide a strong rationale for clinical investigation of SCIO-469 in MDS...