X Xu

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Disabling TNF receptor signaling by induced conformational perturbation of tryptophan-107
    Ramachandran Murali
    Department of Pathology and Laboratory of Medicine and Abramson Cancer Research Center, University of Pennsylvania, 36th Hamilton Walk, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 102:10970-5. 2005
  2. pmc Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation
    S M Kumar
    Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Oncogene 31:4898-911. 2012
  3. pmc Erythropoietin receptor contributes to melanoma cell survival in vivo
    S M Kumar
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Oncogene 31:1649-60. 2012
  4. pmc Generation of melanocytes from induced pluripotent stem cells
    Ruifeng Yang
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Invest Dermatol 131:2458-66. 2011
  5. ncbi request reprint Subcutaneous phaeohyphomycotic cysts caused by Exophiala jeanselmei in a lung transplant patient
    X Xu
    Department of Pathology and Laboratory Medicine, Hospital of University of Pennsylvania, 6 Founfer s Building, 3400 Spruce St, Philadelphia, PA 19104, USA
    Dermatol Surg 27:343-6. 2001
  6. pmc Lymphatic invasion revealed by multispectral imaging is common in primary melanomas and associates with prognosis
    Xiaowei Xu
    Department of Pathology and Laboratory Medicine, and the Melanoma Program of the Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Hum Pathol 39:901-9. 2008
  7. pmc Circulating tumor cells and melanoma progression
    Xiaowei Xu
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Invest Dermatol 130:2349-51. 2010
  8. ncbi request reprint Cellular nodules in congenital pattern nevi
    Xiaowei Xu
    Departments of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, USA
    J Cutan Pathol 31:153-9. 2004
  9. pmc Human skin neural crest progenitor cells are susceptible to BRAF(V600E)-induced transformation
    S M Kumar
    Departments of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
    Oncogene 33:832-41. 2014
  10. ncbi request reprint Extensive retraction artifact correlates with lymphatic invasion and nodal metastasis and predicts poor outcome in early stage breast carcinoma
    Geza Acs
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Am J Surg Pathol 31:129-40. 2007

Detail Information

Publications51

  1. pmc Disabling TNF receptor signaling by induced conformational perturbation of tryptophan-107
    Ramachandran Murali
    Department of Pathology and Laboratory of Medicine and Abramson Cancer Research Center, University of Pennsylvania, 36th Hamilton Walk, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 102:10970-5. 2005
    ..Thus, disabling receptor function by induced conformational changes of active binding surfaces represents an innovative paradigm in structure-based drug design...
  2. pmc Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation
    S M Kumar
    Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    Oncogene 31:4898-911. 2012
    ..The results suggest that CSC phenotype is dynamic and may be acquired through dedifferentiation. Oct4-mediated tumor cell dedifferentiation may have an important role during tumor progression...
  3. pmc Erythropoietin receptor contributes to melanoma cell survival in vivo
    S M Kumar
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Oncogene 31:1649-60. 2012
    ..These data support that EpoR is functional in melanoma and EpoR activation may promote melanoma progression, and suggest that Epo may stimulate angiogenesis and increase survival of melanoma cells under hypoxic condition in vivo...
  4. pmc Generation of melanocytes from induced pluripotent stem cells
    Ruifeng Yang
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Invest Dermatol 131:2458-66. 2011
    ..By inducing iPSCs without viruses, the possibility of integration mutagenesis is alleviated, and these iPSCs are more compatible for cell replacement therapies...
  5. ncbi request reprint Subcutaneous phaeohyphomycotic cysts caused by Exophiala jeanselmei in a lung transplant patient
    X Xu
    Department of Pathology and Laboratory Medicine, Hospital of University of Pennsylvania, 6 Founfer s Building, 3400 Spruce St, Philadelphia, PA 19104, USA
    Dermatol Surg 27:343-6. 2001
    ....
  6. pmc Lymphatic invasion revealed by multispectral imaging is common in primary melanomas and associates with prognosis
    Xiaowei Xu
    Department of Pathology and Laboratory Medicine, and the Melanoma Program of the Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Hum Pathol 39:901-9. 2008
    ..Lymphatic invasion is an underobserved phenomenon in primary melanomas that can be better detected by immunohistochemical staining. The presence of lymphatic invasion may be a clinically useful predictor of regionally metastatic disease...
  7. pmc Circulating tumor cells and melanoma progression
    Xiaowei Xu
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    J Invest Dermatol 130:2349-51. 2010
    ..In this issue, De Giorgi et al. show that CTCs can be detected in melanoma patients using a filtration method, and that a higher percentage of patients with metastatic melanoma have detectable CTCs than do patients with primary melanoma...
  8. ncbi request reprint Cellular nodules in congenital pattern nevi
    Xiaowei Xu
    Departments of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, USA
    J Cutan Pathol 31:153-9. 2004
    ..Although presumed benign, to date, no published long-term follow-up studies have proved the benignity of this lesion...
  9. pmc Human skin neural crest progenitor cells are susceptible to BRAF(V600E)-induced transformation
    S M Kumar
    Departments of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA
    Oncogene 33:832-41. 2014
    ..These results suggest that the hNCPCs are potential targets for BRAF(V600E)-induced melanocytic tumor formation...
  10. ncbi request reprint Extensive retraction artifact correlates with lymphatic invasion and nodal metastasis and predicts poor outcome in early stage breast carcinoma
    Geza Acs
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Am J Surg Pathol 31:129-40. 2007
    ..Rather, it likely signifies important biologic changes that alter tumor-stromal interactions and contribute to lymphatic spread and tumor progression...
  11. ncbi request reprint Lymphatic vessel density is significantly increased in melanoma
    T A Giorgadze
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    J Cutan Pathol 31:672-7. 2004
    ....
  12. pmc Functional erythropoietin autocrine loop in melanoma
    Suresh M Kumar
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Am J Pathol 166:823-30. 2005
    ..The results suggest that the autocrine and paracrine functions of Epo might play a role in malignant transformation of melanocytes and in the survival of melanoma cells in hypoxia and other adverse conditions...
  13. pmc RNA interference-mediated inhibition of erythropoietin receptor expression suppresses tumor growth and invasiveness in A2780 human ovarian carcinoma cells
    Gyorgy Paragh
    Experimental Therapeutics Program, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Am J Pathol 174:1504-14. 2009
    ..Our findings suggest that EpoR may be constitutively active in some cancer cells in the absence of Epo and provide the first evidence for a potential role of an Epo-independent, EpoR-mediated pathway in the growth of some human cancers...
  14. pmc The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes
    Hong Yu
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Am J Pathol 174:2367-77. 2009
    ..In summary, these data demonstrate that a subpopulation of melanocytes possesses the ability to survive BRAF(V600E)-induced senescence, and suggest that p53 inactivation may promote malignant transformation of these cells...
  15. ncbi request reprint Peritumoral lymphatic vessel density and vascular endothelial growth factor C expression in early-stage squamous cell carcinoma of the uterine cervix
    Zoltan Gombos
    Department of Pathology and Laboratory Medicine and Division of Gynecologic Oncology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
    Clin Cancer Res 11:8364-71. 2005
    ..Lymphatic invasion and nodal metastasis plays a major role in the spread of cervical cancer; however, little is known about the mechanisms whereby tumor cells enter the lymphatic system...
  16. ncbi request reprint Differential expression of miRNAs in papillary thyroid carcinoma compared to multinodular goiter using formalin fixed paraffin embedded tissues
    Michael T Tetzlaff
    Department of Pathology and Laboratory Medicine, Hospital for the University of Pennsylvania, 3400 Spruce Street, 7 Founders Pavilion, Philadelphia, PA 19040, USA
    Endocr Pathol 18:163-73. 2007
    ..The ability to utilize FFPE tissue in the molecular characterization of human malignancy will unlock a rich resource for future cancer studies...
  17. ncbi request reprint Biologic and prognostic significance of dermal Ki67 expression, mitoses, and tumorigenicity in thin invasive cutaneous melanoma
    Phyllis A Gimotty
    Melanoma Program of the Abramson Cancer Center, Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, 19104, USA
    J Clin Oncol 23:8048-56. 2005
    ..In this study, we characterized three biomarkers of proliferation (Ki67 expression, dermal mitotic rate [MR], and tumorigenicity) in thin (< or = 1.00 mm) primary cutaneous melanomas and examined their association with prognosis...
  18. ncbi request reprint Histopathologic comparison of nephrogenic fibrosing dermopathy and scleromyxedema
    Cynthia Kucher
    Department of Pathology, Hospital of University of Pennsylvania, Philadelphia Medical Center, Philadelphia, PA 19104, USA
    J Cutan Pathol 32:484-90. 2005
    ..Histopathologic differences with immunophenotypic comparison, to our knowledge, have not been thoroughly studied. We compared these two entities with an emphasis on immunohistochemistry...
  19. ncbi request reprint Reciprocal regulation of MelCAM and AKT in human melanoma
    Gang Li
    The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA
    Oncogene 22:6891-9. 2003
    ..These data link AKT activation with MelCAM expression, and implicate that intervention of MelCAM-AKT signaling axis in melanoma is a potential therapeutical approach...
  20. ncbi request reprint Mutant V600E BRAF increases hypoxia inducible factor-1alpha expression in melanoma
    Suresh M Kumar
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine and The Wistar Institute, Philadelphia, Pennsylvania, USA
    Cancer Res 67:3177-84. 2007
    ....
  21. ncbi request reprint The approach to the patient with a difficult melanocytic lesion
    David E Elder
    Division of Anatomic Pathology, University of Pennsylvania School of Medicine, Philadelphia, PA 19130, USA
    Pathology 36:428-34. 2004
    ..The second principle is to make clinicians and patients specifically aware of the diagnostic difficulty in their lesion, so that management can be undertaken on a true informed consent basis...
  22. ncbi request reprint Autocrine erythropoietin signaling inhibits hypoxia-induced apoptosis in human breast carcinoma cells
    Geza Acs
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, 6 Founders Pavilion, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Cancer Lett 214:243-51. 2004
    ..The resulting decreased apoptotic potential of hypoxic tumor cells may contribute to increased aggressiveness and therapy resistance of breast cancers...
  23. ncbi request reprint Thin primary cutaneous malignant melanoma: a prognostic tree for 10-year metastasis is more accurate than American Joint Committee on Cancer staging
    Phyllis A Gimotty
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Clin Oncol 22:3668-76. 2004
    ....
  24. ncbi request reprint Prognostic significance of erythropoietin expression in human endometrial carcinoma
    Geza Acs
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA
    Cancer 100:2376-86. 2004
    ..The authors recently demonstrated hypoxia-stimulated expression of Epo and Epo receptor (EpoR) in human breast and cervical carcinomas, suggesting a role for autocrine Epo signaling in the hypoxic adaptations of carcinomas...
  25. doi request reprint Angiomatoid Spitz nevus: a clinicopathological study of six cases and a review of the literature
    Michael T Tetzlaff
    Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
    J Cutan Pathol 36:471-6. 2009
    ..The features of classic angiomatoid Spitz nevus are described in the context of important differential diagnostic considerations, particularly regressed malignant melanoma...
  26. ncbi request reprint Expression of Melan-A and Ki-67 in desmoplastic melanoma and desmoplastic nevi
    Cynthia Kucher
    Department of Pathology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Am J Dermatopathol 26:452-7. 2004
    ..Therefore, we investigated whether immunohistochemical staining for Melan-A and Ki-67 expression can be used to discriminate these lesions, distinguishing between epithelioid and spindle cell compartments of the lesions...
  27. ncbi request reprint Can Melan-A replace S-100 and HMB-45 in the evaluation of sentinel lymph nodes from patients with malignant melanoma?
    Cynthia Kucher
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Appl Immunohistochem Mol Morphol 14:324-7. 2006
    ..Melan-A, although very specific, cannot replace the use of S-100 and HMB-45 for the detection of metastatic melanoma in SLNs. It can, however, substitute for HMB-45 with equally good results...
  28. ncbi request reprint Erythropoietin activates the phosphoinositide 3-kinase/Akt pathway in human melanoma cells
    Suresh M Kumar
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine bThe Wistar Institute, Philadelphia, Pennsylvania 19104, USA
    Melanoma Res 16:275-83. 2006
    ..LY294002 also inhibited the cytoprotective effects of Epo in melanoma cells under both normoxic and hypoxic conditions. Our results suggest that Epo promotes melanoma cell survival by activating an Akt-dependent signaling pathway...
  29. ncbi request reprint Uroplakin as a marker for typing metastatic transitional cell carcinoma on fine-needle aspiration specimens
    X Xu
    Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Cancer 93:216-21. 2001
    ..The authors believe that these antibodies have diagnostic potential in cytopathology in the evaluation of metastatic TCC...
  30. ncbi request reprint Nuclear orphan receptor TR3/Nur77 mediates melanoma cell apoptosis
    Hong Yu
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Cancer Biol Ther 6:405-12. 2007
    ..Decreased expression of TR3 in metastatic melanoma cells may contribute to their reduced apoptotic potential and increased resistance to chemotherapy...
  31. ncbi request reprint Clinicopathologic correlation of cutaneous metastases: experience from a cancer center
    Dinesh Sariya
    Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
    Arch Dermatol 143:613-20. 2007
    ..To analyze the clinical, histopathologic, and immunohistochemical characteristics of skin metastases...
  32. ncbi request reprint Podoplanin is a highly sensitive and specific marker to distinguish primary skin adnexal carcinomas from adenocarcinomas metastatic to skin
    Haohai Liang
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Am J Surg Pathol 31:304-10. 2007
    ..Our results suggest that podoplanin can be a useful tool to distinguish primary skin adnexal carcinomas form adenocarcinomas metastatic to skin with high sensitivity (94.5%) and specificity (97.2%)...
  33. ncbi request reprint Low podoplanin expression in pretreatment biopsy material predicts poor prognosis in advanced-stage squamous cell carcinoma of the uterine cervix treated by primary radiation
    Kimberly L Dumoff
    Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, PA, USA
    Mod Pathol 19:708-16. 2006
    ..Prospective studies involving larger numbers of patients are needed to further evaluate the clinical utility of examination of podoplanin expression in patients with cervix carcinoma...
  34. pmc Differential expression of cyclin D1 in the human hair follicle
    Xiaowei Xu
    Department of Pathology, Hospital of University of Pennsylvania, Philadelphia, PA 19104, USA
    Am J Pathol 163:969-78. 2003
    ..Our data also demonstrate that the combination of DNA macroarray, LCM and quantitative real-time PCR is a powerful approach for the study of gene expression in defined cell populations with limited starting material...
  35. ncbi request reprint Immunoprofile of MITF, tyrosinase, melan-A, and MAGE-1 in HMB45-negative melanomas
    Xiaowei Xu
    Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Am J Surg Pathol 26:82-7. 2002
    ..Melanocyte-specific transcription factor is not a useful marker for desmoplastic melanoma...
  36. ncbi request reprint Expression of neurotrophin receptor Trk-C in nevi and melanomas
    Xiaowei Xu
    Hospital of University of Pennsylvania, Philadelphia, PA, USA
    J Cutan Pathol 30:318-22. 2003
    ..In addition, Trk oncogenes have been shown to be rearranged in some non-neuronal neoplasms. Recently, immunoexpression of NT-3 has been shown to be significantly higher in melanomas than in banal nevi on cryostat tissue...
  37. pmc Modulation of mouse neural crest cell motility by N-cadherin and connexin 43 gap junctions
    X Xu
    Biology Department, Goddard Laboratory, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Cell Biol 154:217-30. 2001
    ..Based on these findings, we propose a model in which Cx43alpha1 and N-cadherin may modulate neural crest cell motility by engaging in a dynamic cross-talk with the cell's locomotory apparatus through p120ctn signaling...
  38. pmc Human dermal stem cells differentiate into functional epidermal melanocytes
    Ling Li
    Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, PA 19104, USA
    J Cell Sci 123:853-60. 2010
    ....
  39. ncbi request reprint Differential immunocytochemical staining patterns of uroplakin observed on neoplastic and nonneoplastic tissue fragments obtained from upper urinary tract brush specimens
    Xiaowei Xu
    Cytopathology and Cytometry Section, Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, 3400 Spruce Street 6 Founders Pavilion, Philadelphia, Pennsylvania 19104, USA
    Acta Cytol 46:684-9. 2002
    ..To discern any differences in the distribution of uroplakin expression on neoplastic and nonneoplastic upper urinary tract lesions...
  40. ncbi request reprint Low D2-40 immunoreactivity correlates with lymphatic invasion and nodal metastasis in early-stage squamous cell carcinoma of the uterine cervix
    Kimberly L Dumoff
    Department of Pathology and Laboratory Medicine, Division of Gynecologic Oncology, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Mod Pathol 18:97-104. 2005
    ..Further study of the biological function of the M2A antigen may shed some light on the interaction of tumor cells with lymphatics...
  41. ncbi request reprint Nephrogenic fibrosing dermopathy/nephrogenic systemic fibrosis with diaphragmatic involvement in a patient with respiratory failure
    Cynthia Kucher
    Department of Pathology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA
    J Am Acad Dermatol 54:S31-4. 2006
    ..Autopsy findings showed NFD/NSF involving the skin of all extremities, as well as diffuse diaphragm involvement...
  42. pmc Suppression of human prostate tumor growth by a unique prostate-specific monoclonal antibody F77 targeting a glycolipid marker
    Geng Zhang
    Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104 6082, USA
    Proc Natl Acad Sci U S A 107:732-7. 2010
    ..Thus, the present study indicates that mAb F77 defines a unique prostate cancer marker and shows promising potential for diagnosis and treatment of prostate cancer, especially for androgen-independent metastatic prostate cancer...
  43. pmc Stem cells with neural crest characteristics derived from the bulge region of cultured human hair follicles
    Hong Yu
    Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    J Invest Dermatol 130:1227-36. 2010
    ..The presence of SCs with neural crest characteristics in HFs may offer new opportunities for the use of these cells in regenerative medicine...
  44. ncbi request reprint Scarring alopecia associated with mastocytosis
    Xiaowei Xu
    Departments of Pathology and Laboratory Medicine, Hospital of University of Pennsylvania, Philadelphia, PA 19104, USA
    J Cutan Pathol 30:561-5. 2003
    ..Urticaria pigmentosa is the most common manifestation of cutaneous mastocytosis; others include mastocytoma, diffuse mastocytosis, and telangiectasia macularis eruptiva perstans...
  45. ncbi request reprint A practical approach to selected problematic melanocytic lesions
    Xiaowei Xu
    Department of Pathology and Laboratory Medicine, Hospital of University of Pennsylvania, Philadelphia 19104, USA
    Am J Clin Pathol 121:S3-32. 2004
    ..Immunohistochemical analysis is useful, but it cannot replace careful examination of H&E-stained sections...
  46. ncbi request reprint A tumorigenic subpopulation with stem cell properties in melanomas
    Dong Fang
    Program of Molecular and Cellular Oncogenesis, The Wistar Institute and Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, PA 19104, USA
    Cancer Res 65:9328-37. 2005
    ..Based on these findings, we propose that melanomas can contain a subpopulation of stem cells that contribute to heterogeneity and tumorigenesis. Targeting this population may lead to effective treatments for melanomas...
  47. doi request reprint Periocular papules in nephrogenic systemic fibrosis
    Camille E Introcaso
    J Am Acad Dermatol 59:536-7. 2008
  48. ncbi request reprint Tyrosinase expression in malignant melanoma, desmoplastic melanoma, and peripheral nerve tumors
    Xiaowei Xu
    Arch Pathol Lab Med 127:1083-4; author reply 1084-5. 2003
  49. pmc A structural approach for finding functional modules from large biological networks
    Mutlu Mete
    Department of Applied Science, University of Arkansas at Little Rock, Little Rock, Arkansas, USA
    BMC Bioinformatics 9:S19. 2008
    ..Unfortunately, existing computer-based clustering methods developed to find those modules are either not so accurate or too slow...
  50. ncbi request reprint Transient myeloproliferative disorder causing a vesiculopustular eruption in a phenotypically normal neonate
    Benjamin A Solky
    Department of Dermatology, Harvard University School of Medicine, Boston, Massachusetts 02114, USA
    Pediatr Dermatol 21:551-4. 2004
    ..Biopsy specimens of the lesions showed a sparse, perivascular, atypical, mononuclear infiltrate. We suggest that examination for a TMD be undertaken in neonates with a vesiculopustular eruption and leukemic white blood cell counts...
  51. pmc Automatic delineation of malignancy in histopathological head and neck slides
    Mutlu Mete
    Department of Applied Science, University of Arkansas at Little Rock, Little Rock, Arkansas, USA
    BMC Bioinformatics 8:S17. 2007
    ....

Research Grants5

  1. Ultrasensitive FACTT assays for serum biomarkers
    Xiaowei Xu; Fiscal Year: 2007
    ..With the emerging treatment options for melanoma such as Braf inhibitors and immunotherapies, there is a strong need for ultrasensitive assays to detect early melanoma metastasis. ASSESSMENT: ..
  2. Characterization of neural crest stem cells in human hair follicles.
    Xiaowei Xu; Fiscal Year: 2009
    ..The proposed studies may lead to potential use of these cells in regenerative therapy and establish a novel model to study the etiology of neural crest cells related human diseases. ..
  3. Characterization of neural crest stem cells in human hair follicles.
    Xiaowei Xu; Fiscal Year: 2010
    ..The proposed studies may lead to potential use of these cells in regenerative therapy and establish a novel model to study the etiology of neural crest cells related human diseases. ..
  4. Characterization of neural crest stem cells in human hair follicles
    Xiaowei Xu; Fiscal Year: 2010
    ....