Ren He Xu

Summary

Affiliation: University of Connecticut Health Center
Country: USA

Publications

  1. pmc Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells
    Hui Zeng
    Department of Genetics and Developmental Biology, University of Connecticut Stem Cell Institute, University of Connecticut Health Center, Farmington, Connecticut, United States of America
    PLoS ONE 5:e11853. 2010
  2. pmc NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs
    Ren He Xu
    Department of Genetics and Developmental Biology, University of Connecticut Health Center, University of Connecticut Stem Cell Institute, Farmington, CT 06030, USA
    Cell Stem Cell 3:196-206. 2008
  3. pmc Inhibition of caspase-mediated anoikis is critical for basic fibroblast growth factor-sustained culture of human pluripotent stem cells
    Xiaofang Wang
    University of Connecticut Stem Cell Institute, Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    J Biol Chem 284:34054-64. 2009
  4. doi request reprint Epigenetic regulation of miR-302 by JMJD1C inhibits neural differentiation of human embryonic stem cells
    Jianle Wang
    From the Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut 06030 and
    J Biol Chem 289:2384-95. 2014
  5. doi request reprint Lack of ABCG2 expression and side population properties in human pluripotent stem cells
    Hui Zeng
    Department of Genetics and Developmental Biology, University of Connecticut Stem Cell Institute, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    Stem Cells 27:2435-45. 2009
  6. ncbi request reprint Progresses and challenges in optimization of human pluripotent stem cell culture
    Ge Lin
    University of Connecticut Stem Cell Institute, Department of Genetics and Developmental Biology, Farmington, Connecticut 06030, USA
    Curr Stem Cell Res Ther 5:207-14. 2010
  7. doi request reprint Human embryonic stem cell derivation, maintenance, and differentiation to trophoblast
    Ge Lin
    Department of Genetics and Developmental Biology, Stem Cell Institute, University of Connecticut Health Center, Farmington, CT, USA
    Methods Mol Biol 636:1-24. 2010
  8. doi request reprint Determinants of pluripotency: from avian, rodents, to primates
    Kristen Martins-Taylor
    Department of Genetics and Developmental Biology, University of Connecticut Stem Cell Institute, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    J Cell Biochem 109:16-25. 2010
  9. doi request reprint Concise review: Genomic stability of human induced pluripotent stem cells
    Kristen Martins-Taylor
    Stem Cell Institute, University of Connecticut, Farmington, Connecticut, USA
    Stem Cells 30:22-7. 2012
  10. pmc Role of DNMT3B in the regulation of early neural and neural crest specifiers
    Kristen Martins-Taylor
    Department of Genetics and Developmental Biology, University of Connecticut Health Center, University of Connecticut Stem Cell Institute, Farmington, CT, USA
    Epigenetics 7:71-82. 2012

Collaborators

Detail Information

Publications12

  1. pmc Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells
    Hui Zeng
    Department of Genetics and Developmental Biology, University of Connecticut Stem Cell Institute, University of Connecticut Health Center, Farmington, Connecticut, United States of America
    PLoS ONE 5:e11853. 2010
    ....
  2. pmc NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs
    Ren He Xu
    Department of Genetics and Developmental Biology, University of Connecticut Health Center, University of Connecticut Stem Cell Institute, Farmington, CT 06030, USA
    Cell Stem Cell 3:196-206. 2008
    ..These results suggest that direct binding of TGFbeta/Activin-responsive SMADs to the NANOG promoter plays an essential role in sustaining human ESC self-renewal...
  3. pmc Inhibition of caspase-mediated anoikis is critical for basic fibroblast growth factor-sustained culture of human pluripotent stem cells
    Xiaofang Wang
    University of Connecticut Stem Cell Institute, Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    J Biol Chem 284:34054-64. 2009
    ....
  4. doi request reprint Epigenetic regulation of miR-302 by JMJD1C inhibits neural differentiation of human embryonic stem cells
    Jianle Wang
    From the Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut 06030 and
    J Biol Chem 289:2384-95. 2014
    ....
  5. doi request reprint Lack of ABCG2 expression and side population properties in human pluripotent stem cells
    Hui Zeng
    Department of Genetics and Developmental Biology, University of Connecticut Stem Cell Institute, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    Stem Cells 27:2435-45. 2009
    ..Thus, absence of ABCG2 is a novel feature of human pluripotent stem cells, which distinguishes them from many other stem cells including mouse ESCs, and may be a reason why they are sensitive to suboptimal culture conditions...
  6. ncbi request reprint Progresses and challenges in optimization of human pluripotent stem cell culture
    Ge Lin
    University of Connecticut Stem Cell Institute, Department of Genetics and Developmental Biology, Farmington, Connecticut 06030, USA
    Curr Stem Cell Res Ther 5:207-14. 2010
    ..This review attempts to summarize these progresses and discuss some of the remaining challenges...
  7. doi request reprint Human embryonic stem cell derivation, maintenance, and differentiation to trophoblast
    Ge Lin
    Department of Genetics and Developmental Biology, Stem Cell Institute, University of Connecticut Health Center, Farmington, CT, USA
    Methods Mol Biol 636:1-24. 2010
    ....
  8. doi request reprint Determinants of pluripotency: from avian, rodents, to primates
    Kristen Martins-Taylor
    Department of Genetics and Developmental Biology, University of Connecticut Stem Cell Institute, University of Connecticut Health Center, Farmington, Connecticut 06030, USA
    J Cell Biochem 109:16-25. 2010
    ..We will focus on the molecular and biological features of the cells, as well as the different determinants identified thus far to sustain their pluripotency...
  9. doi request reprint Concise review: Genomic stability of human induced pluripotent stem cells
    Kristen Martins-Taylor
    Stem Cell Institute, University of Connecticut, Farmington, Connecticut, USA
    Stem Cells 30:22-7. 2012
    ..Here, we summarize the progresses in this dynamically evolving field and also discuss how the findings apply to the study and application of hiPSCs...
  10. pmc Role of DNMT3B in the regulation of early neural and neural crest specifiers
    Kristen Martins-Taylor
    Department of Genetics and Developmental Biology, University of Connecticut Health Center, University of Connecticut Stem Cell Institute, Farmington, CT, USA
    Epigenetics 7:71-82. 2012
    ..Our results indicate that DNMT3B mediates large-scale methylation patterns in hESCs and that DNMT3B deficiency in the cells alters the timing of their neuronal differentiation and maturation...
  11. doi request reprint Vaccination with human pluripotent stem cells generates a broad spectrum of immunological and clinical responses against colon cancer
    Yi Li
    Department of Immunology, University of Connecticut School of Medicine, Farmington, Connecticut 06030 1601, USA
    Stem Cells 27:3103-11. 2009
    ..We conclude that the hESC-based vaccine is a promising modality for immunotherapy of cancer...
  12. doi request reprint Efficient differentiation of human iPSC-derived mesenchymal stem cells to chondroprogenitor cells
    Rosa M Guzzo
    Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, CT, USA
    J Cell Biochem 114:480-90. 2013
    ..These studies represent a first step toward identifying the most suitable iPSC progeny for developing cell-based approaches to repair joint cartilage damage...