Long Xu

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. doi request reprint Cholesterol domains in cationic lipid/DNA complexes improve transfection
    Long Xu
    School of Pharmacy, University of Colorado Denver, 4200 E Ninth Avenue, Denver, Colorado, USA
    Biochim Biophys Acta 1778:2177-81. 2008
  2. pmc Ligands located within a cholesterol domain enhance gene delivery to the target tissue
    Long Xu
    School of Pharmacy, University of Colorado Denver, 12850 Montview Blvd, Aurora, CO, United States
    J Control Release 160:57-63. 2012
  3. pmc The effect of cholesterol domains on PEGylated liposomal gene delivery in vitro
    Long Xu
    School of Pharmacy, University of Colorado Denver, 12850 E Montview Blvd, Aurora, CO 80045, USA
    Ther Deliv 2:451-60. 2011
  4. pmc Effect of cholesterol nanodomains on the targeting of lipid-based gene delivery in cultured cells
    Long Xu
    School of Pharmacy, University of Colorado Denver, 12700 East 19th Avenue, Aurora, Colorado 80045, USA
    Mol Pharm 7:1311-7. 2010

Collaborators

Detail Information

Publications4

  1. doi request reprint Cholesterol domains in cationic lipid/DNA complexes improve transfection
    Long Xu
    School of Pharmacy, University of Colorado Denver, 4200 E Ninth Avenue, Denver, Colorado, USA
    Biochim Biophys Acta 1778:2177-81. 2008
    ..Additional studies quantifying albumin binding suggest that cholesterol domains in the lipid/DNA complex do not bind protein, and this may enable these moieties to enhance transfection by facilitating membrane fusion...
  2. pmc Ligands located within a cholesterol domain enhance gene delivery to the target tissue
    Long Xu
    School of Pharmacy, University of Colorado Denver, 12850 Montview Blvd, Aurora, CO, United States
    J Control Release 160:57-63. 2012
    ..These results demonstrate that the microenvironment of the ligand can affect gene delivery to tumors, and show that ligand-mediated delivery can be enhanced by locating targeting ligands within a cholesterol domain...
  3. pmc The effect of cholesterol domains on PEGylated liposomal gene delivery in vitro
    Long Xu
    School of Pharmacy, University of Colorado Denver, 12850 E Montview Blvd, Aurora, CO 80045, USA
    Ther Deliv 2:451-60. 2011
    ..e., within or excluded from the domain)...
  4. pmc Effect of cholesterol nanodomains on the targeting of lipid-based gene delivery in cultured cells
    Long Xu
    School of Pharmacy, University of Colorado Denver, 12700 East 19th Avenue, Aurora, Colorado 80045, USA
    Mol Pharm 7:1311-7. 2010
    ....