Zhengzhi Xie

Summary

Affiliation: University of Louisville
Country: USA

Publications

  1. doi request reprint Detoxification of aldehydes by histidine-containing dipeptides: from chemistry to clinical implications
    Zhengzhi Xie
    Diabetes and Obesity Center, University of Louisville, Louisville, KY 40202, USA
    Chem Biol Interact 202:288-97. 2013
  2. doi request reprint Dietary carnosine prevents early atherosclerotic lesion formation in apolipoprotein E-null mice
    Oleg A Barski
    Diabetes and Obesity Center, School of Medicine, University of Louisville, Louisville, KY 40202, USA
    Arterioscler Thromb Vasc Biol 33:1162-70. 2013
  3. pmc Reductive metabolism increases the proinflammatory activity of aldehyde phospholipids
    Elena Vladykovskaya
    Diabetes and Obesity Center, School of Medicine, University of Louisville, Louisville, KY 40202, USA
    J Lipid Res 52:2209-25. 2011
  4. pmc Catalytic reduction of carbonyl groups in oxidized PAPC by Kvβ2 (AKR6)
    Zhengzhi Xie
    Diabetes and Obesity Center, University of Louisville, Louisville, KY 40202, United States
    Chem Biol Interact 191:255-60. 2011

Collaborators

Detail Information

Publications4

  1. doi request reprint Detoxification of aldehydes by histidine-containing dipeptides: from chemistry to clinical implications
    Zhengzhi Xie
    Diabetes and Obesity Center, University of Louisville, Louisville, KY 40202, USA
    Chem Biol Interact 202:288-97. 2013
    ..Thus, treatment with carnosine and related histidine dipeptides may be a promising strategy for the prevention and treatment of diseases associated with high carbonyl load...
  2. doi request reprint Dietary carnosine prevents early atherosclerotic lesion formation in apolipoprotein E-null mice
    Oleg A Barski
    Diabetes and Obesity Center, School of Medicine, University of Louisville, Louisville, KY 40202, USA
    Arterioscler Thromb Vasc Biol 33:1162-70. 2013
    ....
  3. pmc Reductive metabolism increases the proinflammatory activity of aldehyde phospholipids
    Elena Vladykovskaya
    Diabetes and Obesity Center, School of Medicine, University of Louisville, Louisville, KY 40202, USA
    J Lipid Res 52:2209-25. 2011
    ..Thus, vascular inflammation in atherosclerotic lesions is likely to be regulated by metabolism of phospholipid aldehydes in macrophages...
  4. pmc Catalytic reduction of carbonyl groups in oxidized PAPC by Kvβ2 (AKR6)
    Zhengzhi Xie
    Diabetes and Obesity Center, University of Louisville, Louisville, KY 40202, United States
    Chem Biol Interact 191:255-60. 2011
    ..01). These results suggest that Kvβ could serve as a sensor of lipid oxidation via its catalytic activity and thereby alter Kv currents under conditions of oxidative stress...