J M Wyss

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. pmc Perinatal taurine exposure alters renal potassium excretion mechanisms in adult conscious rats
    Sanya Roysommuti
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    J Biomed Sci 17:S29. 2010
  2. pmc Adult renal function is modified by perinatal taurine status in conscious male rats
    Sanya Roysommuti
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    J Biomed Sci 17:S31. 2010
  3. pmc High sugar intake via the renin-angiotensin system blunts the baroreceptor reflex in adult rats that were perinatally depleted of taurine
    Atcharaporn Thaeomor
    Department of Physiology Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    J Biomed Sci 17:S30. 2010
  4. ncbi request reprint Age-related decline in water maze learning and memory in rats: strain differences
    J M Wyss
    Department of Cell Biology, University of Alabama at Birmingham, 35294 0019, USA
    Neurobiol Aging 21:671-81. 2000
  5. ncbi request reprint Age-related decline in spatial learning and memory: attenuation by captopril
    J Michael Wyss
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0006, USA
    Clin Exp Hypertens 25:455-74. 2003
  6. ncbi request reprint Effects of hormone replacement therapy on the sympathetic nervous system and blood pressure
    J Michael Wyss
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294 0006, USA
    Curr Hypertens Rep 5:241-6. 2003
  7. ncbi request reprint Antihypertensive and cognitive effects of grape polyphenols in estrogen-depleted, female, spontaneously hypertensive rats
    Ning Peng
    Dept of Cell Biology, University of Alabama at Birmingham, 1900 Univ Blvd THT 950, Birmingham, AL 35294 0006, USA
    Am J Physiol Regul Integr Comp Physiol 289:R771-5. 2005
  8. ncbi request reprint Distribution of neurons in the anterior hypothalamic nucleus activated by blood pressure changes in the rat
    J M Wyss
    Department of Cell Biology, University of Alabama at Birmingham, 35294 0019, USA
    Brain Res Bull 49:163-72. 1999
  9. ncbi request reprint The role of the nervous system in hypertension
    J M Wyss
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Curr Hypertens Rep 3:255-62. 2001
  10. ncbi request reprint Hepatic denervation chronically elevates arterial pressure in Wistar-Kyoto rats
    S H Carlson
    Vascular Biology and Hypertension Program of the Department of Medicine, University of Alabama at Birmingham, USA
    Hypertension 32:46-51. 1998

Collaborators

Detail Information

Publications45

  1. pmc Perinatal taurine exposure alters renal potassium excretion mechanisms in adult conscious rats
    Sanya Roysommuti
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    J Biomed Sci 17:S29. 2010
    ..The present data indicates that perinatal taurine exposure only mildly influences renal potassium excretion in adult male and female rats...
  2. pmc Adult renal function is modified by perinatal taurine status in conscious male rats
    Sanya Roysommuti
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    J Biomed Sci 17:S31. 2010
    ..The present data indicate that in adult male rats, both perinatal supplementation and depletion of taurine can alter renal hemodynamics, and these effects are differentially time-dependent...
  3. pmc High sugar intake via the renin-angiotensin system blunts the baroreceptor reflex in adult rats that were perinatally depleted of taurine
    Atcharaporn Thaeomor
    Department of Physiology Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    J Biomed Sci 17:S30. 2010
    ..The present data indicate that in perinatal taurine depleted female rats, the renin-angiotensin system underlines the ability of high sugar intake to blunt baroreceptor responses...
  4. ncbi request reprint Age-related decline in water maze learning and memory in rats: strain differences
    J M Wyss
    Department of Cell Biology, University of Alabama at Birmingham, 35294 0019, USA
    Neurobiol Aging 21:671-81. 2000
    ..Thus, in these three strains, age-related impairment of spatial memory proceeds at different rates...
  5. ncbi request reprint Age-related decline in spatial learning and memory: attenuation by captopril
    J Michael Wyss
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0006, USA
    Clin Exp Hypertens 25:455-74. 2003
    ..Further, the results indicate that the memory enhancing effects of captopril are not primarily the due to the ability of captopril to lower blood pressure...
  6. ncbi request reprint Effects of hormone replacement therapy on the sympathetic nervous system and blood pressure
    J Michael Wyss
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294 0006, USA
    Curr Hypertens Rep 5:241-6. 2003
    ..This review examines the evidence supporting estrogen's ability to modulate sympathetic nervous system tone and thereby decrease arterial pressure...
  7. ncbi request reprint Antihypertensive and cognitive effects of grape polyphenols in estrogen-depleted, female, spontaneously hypertensive rats
    Ning Peng
    Dept of Cell Biology, University of Alabama at Birmingham, 1900 Univ Blvd THT 950, Birmingham, AL 35294 0006, USA
    Am J Physiol Regul Integr Comp Physiol 289:R771-5. 2005
    ..These results indicate that grape seed polyphenols decrease arterial pressure in SHR, probably via an antioxidant mechanism...
  8. ncbi request reprint Distribution of neurons in the anterior hypothalamic nucleus activated by blood pressure changes in the rat
    J M Wyss
    Department of Cell Biology, University of Alabama at Birmingham, 35294 0019, USA
    Brain Res Bull 49:163-72. 1999
    ..In contrast, elevation in arterial pressure increased Fos labeling throughout the anterior hypothalamic nucleus and to a lesser extent in the paraventricular nucleus...
  9. ncbi request reprint The role of the nervous system in hypertension
    J M Wyss
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Curr Hypertens Rep 3:255-62. 2001
    ....
  10. ncbi request reprint Hepatic denervation chronically elevates arterial pressure in Wistar-Kyoto rats
    S H Carlson
    Vascular Biology and Hypertension Program of the Department of Medicine, University of Alabama at Birmingham, USA
    Hypertension 32:46-51. 1998
    ..These results suggest that in the rat, although hepatic osmoreceptors contribute to long-term arterial pressure regulation, they contribute much less to dietary NaCl-induced changes in arterial pressure...
  11. ncbi request reprint Estrogen depletion induces NaCl-sensitive hypertension in female spontaneously hypertensive rats
    Z Fang
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294-0019, USA
    Am J Physiol Regul Integr Comp Physiol 281:R1934-9. 2001
    ..Furthermore, these results demonstrate that dietary phytoestrogens can have a major impact on the interpretation of studies into the physiological role of estrogen in females...
  12. pmc Effects of botanical dietary supplements on cardiovascular, cognitive, and metabolic function in males and females
    Scott Carlson
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Gend Med 5:S76-90. 2008
    ..After menopause, the rates of these diseases in women eventually approximate those in men. The loss of endogenous estrogen at menopause has been traditionally believed to be the primary factor involved in these changes...
  13. ncbi request reprint Long-term telemetric recording of arterial pressure and heart rate in mice fed basal and high NaCl diets
    S H Carlson
    Department of Cell Biology, University of Alabama at Birmingham, AL, USA
    Hypertension 35:E1-5. 2000
    ..Thus, the data demonstrate that telemetric recording of long-term arterial pressure and heart rate provides a powerful tool with which to define the mechanisms of cardiovascular control in mice...
  14. pmc Chronic dietary kudzu isoflavones improve components of metabolic syndrome in stroke-prone spontaneously hypertensive rats
    Ning Peng
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0006, USA
    J Agric Food Chem 57:7268-73. 2009
    ..These results indicate that long-term dietary kudzu root extract supplementation can improve glucose, lipid, and blood pressure control in intact and ovariectomized SP-SHR...
  15. ncbi request reprint Hepatic denervation does not affect plasma vasopressin response to intragastric hypertonic saline in conscious rats
    S H Carlson
    Vascular Biology and Hypertension Program, Department of Medicine, and Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0019, USA
    Am J Physiol 277:E161-7. 1999
    ....
  16. ncbi request reprint Pressor and depressor sites are intermingled in the cingulate cortex of the rat
    G D Fisk
    Department of Psychology, The University of Alabama at Birmingham, USA
    Brain Res 754:204-12. 1997
    ....
  17. doi request reprint Tissue distribution of puerarin and its conjugated metabolites in rats assessed by liquid chromatography-tandem mass spectrometry
    Jeevan K Prasain
    Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Phytomedicine 16:65-71. 2009
    ..This report identifying puerarin in several organs including kidney and pancreas may explain its beneficial effects in diabetes...
  18. ncbi request reprint The effectiveness of Hering's nerve stimulation in controlling penicillin-induced seizures in the rat is dependent on the amygdala
    R Shane Tubbs
    Department of Cell Biology, University of Alabama at Birmingham, USA
    Pediatr Neurosurg 37:231-4. 2002
    ..This study tests the hypothesis that the ability of Hering's nerve stimulation (HNS) to blunt seizure activity is dependent on the availability of dopamine in the amygdala...
  19. ncbi request reprint Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometry
    Jeevan K Prasain
    Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    J Agric Food Chem 52:3708-12. 2004
    ..Study of these metabolites may provide further understanding of the health beneficial effects of puerarin in kudzu dietary supplements...
  20. ncbi request reprint Pharmacokinetic study of puerarin in rat serum by liquid chromatography tandem mass spectrometry
    Jeevan K Prasain
    Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Biomed Chromatogr 21:410-4. 2007
    ..54 +/- 2.03 mg/L), T(max) (0.68 +/- 0.37 h), AUC(0-t) (7.29 +/- 3.79 mg h/L), AUC(0-infinity) (9.17 +/- 4.87 mg h/L), T(1/2) (1.7 +/- 0.6 h), CL/F (7.24 +/- 4.27 L/h/kg) and V/F (17.88 +/- 13.55 L/h/kg)...
  21. ncbi request reprint The role of the central nervous system in NaCl-sensitive hypertension in spontaneously hypertensive rats
    S H Carlson
    Department of Biology, Luther College, Birmingham, Alabama, USA
    Am J Hypertens 14:155S-162S. 2001
    ..Finally, our evidence demonstrates that these factors lead to an increased rise in sympathetic nervous system activity during the early wake phase in SHR on a high NaCl diet, contributing to NaCl-sensitive hypertension in SHR...
  22. ncbi request reprint Estrogen depletion increases blood pressure and hypothalamic norepinephrine in middle-aged spontaneously hypertensive rats
    Ning Peng
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Ala 35294 0006, USA
    Hypertension 41:1164-7. 2003
    ..These data suggest that both dietary NaCl excess and estrogen depletion raise arterial pressure in middle-aged female SHR by a decreasing hypothalamic norepinephrine...
  23. ncbi request reprint Insulin-exacerbated hypertension in captopril-treated spontaneously hypertensive rats: role of sympathoexcitation
    Sanya Roysommuti
    Department of Cell Biology, University of Alabama at Birmingham, 35294 0006, USA
    Can J Physiol Pharmacol 81:1036-41. 2003
    ..These data indicate that in SHR, the ability of insulin to increase blood pressure is closely related to sympathoexcitation, which is unresponsive to blockade of angiotensin-converting enzyme...
  24. pmc Flavonoids and age-related disease: risk, benefits and critical windows
    J K Prasain
    Department Pharmacology and Toxicology of the University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Maturitas 66:163-71. 2010
    ..Thus, as the population ages, it is important to determine the impact of these agents on prevention/attenuation of disease, including optimal exposure (intake, timing/duration) and potential contraindications...
  25. pmc Neurohormonal regulation of the sympathetic nervous system: new insights into central mechanisms of action
    Scott H Carlson
    Department of Cell Biology, University of Alabama at Birmingham, 1900 University Boulevard, THT 950, Birmingham, AL 35294, USA
    Curr Hypertens Rep 10:233-40. 2008
    ..The relative importance of these mechanisms to blood pressure control remains to be fully elucidated...
  26. ncbi request reprint Genistein attenuates the hypertensive effects of dietary NaCl in hypertensive male rats
    Taehyeon M Cho
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294 0006, USA
    Endocrinology 148:5396-402. 2007
    ..Thus, in male SHR-SP, dietary genistein blunts NaCl-sensitive hypertension, and these effects may be regulated, in part, by the autonomic nervous system and/or metabolic mechanisms...
  27. pmc Enhanced hypotensive, bradycardic, and hypnotic responses to alpha2-adrenergic agonists in spinophilin-null mice are accompanied by increased G protein coupling to the alpha2A-adrenergic receptor
    R Lu
    Department of Physiology and Biophysics, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Mol Pharmacol 78:279-86. 2010
    ..These findings suggest that eliminating spinophilin expression in native tissues leads to an enhanced receptor/G protein coupling efficiency that contributes to sensitization of receptor mediated responses in vivo...
  28. ncbi request reprint Neuregulin-1beta modulates in vivo entorhinal-hippocampal synaptic transmission in adult rats
    S Roysommuti
    Department of Cell Biology, 1900 University Boulevard, THT 950, University of Alabama at Birmingham, 35294 0006, USA
    Neuroscience 121:779-85. 2003
    ..These observations indicate that NRG-1 is not only a developmental growth factor, but also modifies synaptic transmission in adult rat brain...
  29. ncbi request reprint Blood pressure and NaCl-sensitive hypertension are influenced by angiotensin-converting enzyme gene expression in transgenic mice
    Scott H Carlson
    Vascular Biology and Hypertension Program of the Department of Medicine, University of Alabama at Birmingham, USA
    Hypertension 39:214-8. 2002
    ....
  30. ncbi request reprint Alpha2A-adrenergic receptors mediate sympathoinhibitory responses to atrial natriuretic peptide in the mouse anterior hypothalamic nucleus
    Ning Peng
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294 0006, USA
    Hypertension 41:571-5. 2003
    ....
  31. doi request reprint Simultaneous determination of 11 phytoestrogens in human serum using a 2 min liquid chromatography/tandem mass spectrometry method
    Jeevan K Prasain
    Departments of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 878:994-1002. 2010
    ..75 mL/min. This LC-MS/MS method is very useful for high-throughput analysis of phytoestrogens and proved to be simple, sensitive, reproducible, and reliable...
  32. ncbi request reprint Excess dietary glucose alters renal function before increasing arterial pressure and inducing insulin resistance
    Sanya Roysommuti
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Thailand
    Am J Hypertens 15:773-9. 2002
    ..This study tests the hypothesis that the initial effect of a long-term high carbohydrate diet is a renin-angiotensin system dependant impairment of renal function...
  33. ncbi request reprint Estrogen depletion differentially affects blood pressure depending on age in Long-Evans rats
    John T Clark
    Department of Physiology, Meharry Medical College, Nashville, TN 37208, USA
    Endocrine 25:173-86. 2004
    ..We suggest that chronic increases in aldosterone and sympathetic tone underlie the hypertensive effects of estrogen depletion...
  34. ncbi request reprint Old rats remember old tricks; memories of the water maze persist for 12 months
    Thomas van Groen
    Department of Neuroscience and Neurology, University of Kuopio, Canthia Building, P O Box 1627, Finland
    Behav Brain Res 136:247-55. 2002
    ..Together these data indicate that 24-month-old rats can learn spatial tasks well and that the performance of old rats in spatial tasks can be significantly influenced by prior exposure to that task, even 12 months earlier...
  35. ncbi request reprint Retrosplenial cortex lesions of area Rgb (but not of area Rga) impair spatial learning and memory in the rat
    Thomas van Groen
    Department of Neuroscience and Neurology, University of Kuopio, Kuopio University Hospital, P O Box 1627, FIN 70211 Kuopio, Finland
    Behav Brain Res 154:483-91. 2004
    ..The data highlight the unique and complex contribution of each area of the retrosplenial cortex to behavior...
  36. pmc Botanicals for age-related diseases: from field to practice
    Connie M Weaver
    Foods and Nutrition, Rutgers University, New Brunswick, NJ, USA
    Am J Clin Nutr 87:493S-7S. 2008
    ..Botanicals and their relation to bone antiresorptive capacity, cognitive function, vascular effects, and cancer are principal themes in our center...
  37. ncbi request reprint Increased PI3-kinase in presympathetic brain areas of the spontaneously hypertensive rat
    Shereeni J Veerasingham
    Department of Physiology and Functional Genomics, University of Florida, Gainesville 32610, USA
    Circ Res 96:277-9. 2005
    ..Furthermore, normalized PI3-kinase p85alpha/p110delta expression within the PVN might contribute to the overall effect of captopril, perhaps attributable to a consequent decrease in NE availability...
  38. ncbi request reprint The therapeutic potential of hepatocyte growth factor for myocardial infarction and heart failure
    Hongkui Jin
    Department of Translational Oncology, Genentech, Inc, South San Francisco, CA 97080, USA
    Curr Pharm Des 10:2525-33. 2004
    ..Clinical trials are needed to investigate the therapeutic potential of HGF for postinfarction heart failure in humans...
  39. ncbi request reprint Age-related decreases in gonadal hormones in Long-Evans rats: relationship to rise in arterial pressure
    Ian H Fentie
    Department of Pathology, Meharry Medical College, Nashville, TN 37208, USA
    Endocrine 25:15-22. 2004
    ..Thus, by middle age, male and female rats are exposed to less gonadal hormone/altered patterns of availability, exhibit decrements in reproductive function, and display an increase in systolic blood pressure...
  40. pmc Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice
    Scott P Heximer
    J Clin Invest 111:1259. 2003
  41. ncbi request reprint Heightened epithelial Na+ channel-mediated Na+ absorption in a murine polycystic kidney disease model epithelium lacking apical monocilia
    Dragos Olteanu
    Department of Physiology, Univ of Alabama at Birmingham, MCLM 740, 1918 University Blvd, 35294 0005, USA
    Am J Physiol Cell Physiol 290:C952-63. 2006
    ..cilium-competent controls. When the genetic lesion causes loss or malformation of the monocilium, ENaC-driven Na(+) hyperabsorption may explain the rapid emergence of severe hypertension in a majority of patients with ARPKD...
  42. ncbi request reprint Pathways by which dietary salt affects blood pressure and the nervous system
    J Michael Wyss
    Hypertension 47:638-9. 2006
  43. ncbi request reprint The role of the laterodorsal nucleus of the thalamus in spatial learning and memory in the rat
    Thomas van Groen
    Department of Neuroscience and Neurology, University of Kuopio, FIN 70211 Kuopio, Finland
    Behav Brain Res 136:329-37. 2002
    ..These findings support the hypothesis that together with the anterior thalamic nuclei, LD plays a role in spatial learning and memory...
  44. ncbi request reprint Effects of G207, a conditionally replication-competent oncolytic herpes simplex virus, on the developing mammalian brain
    Andrew E Radbill
    Department of Cardiology, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    J Neurovirol 13:118-29. 2007
    ..Furthermore, patients in such a study will need to be closely monitored for the development of hydrocephalus...
  45. pmc Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice
    Scott P Heximer
    Department of Cell Biology and Physiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Clin Invest 111:445-52. 2003
    ....

Research Grants2

  1. Birmingham Science Education Partnership: Middle School Inquiry-Based Learning
    J Wyss; Fiscal Year: 2007
    ..The proven partnership of UAB, BCS and McWane Center will provide a test of the power, cost-effectiveness and self-sustainability of this inquiry-based model. ..