Research Topics
| Jonathan K WynnSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Event-related potential examination of facial affect processing in bipolar disorder and schizophreniaJ K Wynn
VA Greater Los Angeles Healthcare System, MIRECC, Los Angeles, CA 90073, USA
Psychol Med 43:109-17. 2013..Patients with bipolar disorder exhibit consistent deficits in facial affect identification at both behavioral and neural levels. However, little is known about which stages of facial affect processing are dysfunctional...
Mismatch negativity, social cognition, and functioning in schizophrenia patientsJonathan K Wynn
Mental Illness Research, Education and Clinical Center, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California, USA
Biol Psychiatry 67:940-7. 2010..Prior studies found associations between mismatch negativity (MMN), an event-related potential response indexing early auditory processing, and functioning in schizophrenia patients...- Increased extent of object-selective cortex in schizophreniaJonathan K Wynn
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, USA
Psychiatry Res 164:97-105. 2008..The findings of abnormal spatial organization of LO in schizophrenia patients may converge with behavioral evidence of deficits in schizophrenia patients for object-recognition tasks that are believed to be mediated by LO activity... - Impaired anticipatory event-related potentials in schizophreniaJonathan K Wynn
VA Greater Los Angeles Healthcare System, University of California, Los Angeles, USA
Int J Psychophysiol 77:141-9. 2010..Schizophrenia patients demonstrate diminished motor- and non-motor-related anticipatory processing, which may have wide-ranging adverse functional consequences... - Using event related potentials to explore stages of facial affect recognition deficits in schizophreniaJonathan K Wynn
VA Greater Los Angeles Healthcare System, MIRECC, Building 210, Los Angeles, CA 90073, USA
Schizophr Bull 34:679-87. 2008..Our results imply that abnormalities in the later stage of feature decoding could potentially underlie emotion identification deficits in schizophrenia... - Effects of olanzapine, risperidone and haloperidol on prepulse inhibition in schizophrenia patients: a double-blind, randomized controlled trialJonathan K Wynn
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA
Schizophr Res 95:134-42. 2007..The results are discussed in terms of animal models, neural substrates, and treatment implications... 
Exploring the short term visual store in schizophrenia using the attentional blinkJonathan K Wynn
Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, United States
J Psychiatr Res 40:599-605. 2006..The findings suggest that the enhanced AB effect in schizophrenia reflects an abnormality in their short term visual memory, as opposed to their enhanced susceptibility to visual masking...- Event-related gamma activity in schizophrenia patients during a visual backward-masking taskJonathan K Wynn
Department of Psychology, UCLA, Los Angeles, CA, USA
Am J Psychiatry 162:2330-6. 2005..This study examined event-related gamma range activity during a visual backward-masking task in schizophrenia patients and normal comparison subjects... - Sensorimotor gating, orienting and social perception in schizophreniaJonathan K Wynn
Department of Psychiatry and Biobehavioral Science, Geffen School of Medicine at UCLA, United States
Schizophr Res 73:319-25. 2005..By showing a link between sensorimotor gating and social perception, this study supports social cognition's potential role as a mediator of the relationship between neurocognition and social functioning in schizophrenia... - The functional relationship between visual backward masking and prepulse inhibitionJonathan K Wynn
Department of Psychology, University of Southern California, Los Angeles, California 90089, USA
Psychophysiology 41:306-12. 2004..The data are consistent with the hypothesis that recovery from backward masking effects is affected by sensory gating acting in part to gate out the interruptive effects of the mask... - Altered dynamic coupling of lateral occipital complex during visual perception in schizophreniaPhilippe Olivier Harvey
Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA
Neuroimage 55:1219-26. 2011..However, the functional connectivity of LO with other brain regions during visual perception has not been directly investigated in schizophrenia... - Regional brain activity during early visual perception in unaffected siblings of schizophrenia patientsJunghee Lee
Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California 90095 6968, USA
Biol Psychiatry 68:78-85. 2010..We examined the neural substrates of visual backward performance in unaffected sibling of schizophrenia patients using functional magnetic resonance imaging (fMRI)... - Functional neuroanatomy of visual masking deficits in schizophreniaMichael F Green
Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA 90095 6968, USA
Arch Gen Psychiatry 66:1295-303. 2009..Patients with schizophrenia reliably show deficits on visual masking, and these procedures have been used to explore vulnerability to schizophrenia, probe underlying neural circuits, and help explain functional outcome... - Electrophysiological correlates of emotional responding in schizophreniaWilliam P Horan
Department of Psychiatry, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
J Abnorm Psychol 119:18-30. 2010..However, they showed a disruption in a later component associated with sustained attentional processing of emotional stimuli... - Efficacy and specificity of social cognitive skills training for outpatients with psychotic disordersWilliam P Horan
Department of Veterans Affairs VISN 22 Mental Illness Research, Education, and Clinical Center, Los Angeles, CA, USA
J Psychiatr Res 45:1113-22. 2011..Findings provide guidance for continued efforts to maximize the benefits of social cognitive interventions... - Cross-diagnostic comparison of duration mismatch negativity and P3a in bipolar disorder and schizophreniaCarol Jahshan
Mental Illness Research, Education, and Clinical Center MIRECC, VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
Bipolar Disord 14:239-48. 2012..Furthermore, MMN and P3a have not been examined between diagnostic subgroups of patients with bipolar disorder. We evaluated MMN and P3a in patients with bipolar disorder compared to patients with schizophrenia and healthy controls... - The attentional blink in schizophrenia: isolating the perception/attention interfaceKristopher I Mathis
Mental Illness Research, Education and Clinical Center MIRECC, VA Greater Los Angeles Healthcare System, CA 90073, USA
J Psychiatr Res 45:1346-51. 2011..This performance pattern on the AB task suggests that patients with schizophrenia exhibit both deficits in visual processing at the interface of perceptual and attentional processing and a general attentional deficit... - Further support for the role of dysfunctional attitudes in models of real-world functioning in schizophreniaWilliam P Horan
VA Greater Los Angeles Healthcare System, University of California, Department of Psychiatry and Biobehavioral Sciences, Los Angeles, CA 90073, USA
J Psychiatr Res 44:499-505. 2010..These findings support the value of dysfunctional attitudes for understanding the determinants of outcome in schizophrenia and suggest that therapeutic interventions targeting these attitudes may facilitate functional recovery... - How do schizophrenia patients use visual information to decode facial emotion?Junghee Lee
Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA 90095 6968, USA
Schizophr Bull 37:1001-8. 2011..This study provides direct evidence that schizophrenia patients employ an atypical strategy of using visual information to recognize emotional faces... - Visual masking in schizophrenia: overview and theoretical implicationsMichael F Green
VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA
Schizophr Bull 37:700-8. 2011..Finally, we will suggest a possible mechanism that could explain the patterns of masking findings and other visual processing findings in schizophrenia... - Nonconscious and conscious color priming in schizophreniaCarol Jahshan
VISN 22 Mental Illness Research, Education and Clinical Center, VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA
J Psychiatr Res 46:1312-7. 2012..These results imply that the well-documented visual processing deficits in this illness likely occur at later, percept-dependent stages of processing... - Prepulse facilitation and prepulse inhibition in schizophrenia patients and their unaffected siblingsJonathan K Wynn
Department of Psychology (MED, University of Southern California, Los Angeles, California 90073, USA
Biol Psychiatry 55:518-23. 2004.... - Intact motivated attention in schizophrenia: evidence from event-related potentialsWilliam P Horan
VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, United States
Schizophr Res 135:95-9. 2012..Emotional stimuli captured attentional resources in people with schizophrenia even when the emotional stimuli were task-irrelevant, suggesting intact motivated attention at the level of early electrophysiological responding... - Impaired implicit learning in schizophreniaWilliam P Horan
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA, USA
Neuropsychology 22:606-17. 2008..Discussion focuses on possible explanations for schizophrenia patients' poor probabilistic classification task performance... - Perception measurement in clinical trials of schizophrenia: promising paradigms from CNTRICSMichael F Green
Semel Institute, UCLA, CA, USA
Schizophr Bull 35:163-81. 2009..This manuscript describes the ways in which each of these tasks met the criteria used by the breakout group to evaluate and recommend tasks for further development... - Social cognitive skills training in schizophrenia: an initial efficacy study of stabilized outpatientsWilliam P Horan
Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, Los Angeles, California, USA
Schizophr Res 107:47-54. 2009.... - An electrophysiological investigation of attentional blink in schizophrenia: Separating perceptual and attentional processesKristopher I Mathis
VA Desert Pacific Mental Illness Research, Education, and Clinical Center MIRECC, VA Greater Los Angeles Healthcare System, West Los Angeles VA Healthcare Center, 11301 Wilshire Blvd, Bldg 210, Room 130, Los Angeles, CA 90073, USA Electronic address
Int J Psychophysiol 86:108-13. 2012..Mean ssVEP amplitude did not differ between the groups, and the differences in P300 remained after controlling for ssVEP. These results suggest that the observed AB deficits were due to attentional, not perceptual, processing deficits... - An analysis of categorical perception of facial emotion in schizophreniaKimmy S Kee
California State University Channel Islands, United States
Schizophr Res 87:228-37. 2006.... - Object substitution masking in schizophrenia: an event-related potential analysisJonathan K Wynn
Veterans Affairs Greater Los Angeles Healthcare System Los Angeles, CA, USA Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, USA
Front Psychol 4:30. 2013..Considering that the VAN is thought to reflect reentrant processing, one interpretation of the findings is that patients' lack of VAN response and poorer performance may be related to dysfunctional reentrant processing... - Relationship between auditory processing and affective prosody in schizophreniaCarol Jahshan
Sierra Pacific Mental Illness Research, Education and Clinical Center MIRECC, VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA
Schizophr Res 143:348-53. 2013..These findings provide support for bottom-up (e.g., perceptually based) cognitive remediation approaches... - Quantitative EEG and low resolution electromagnetic tomography (LORETA) imaging of patients with persistent auditory hallucinationsSeung Hwan Lee
Department of Psychiatry, Ilsanpaik Hospital, Inje University College of Medicine, 2240 Daehwa dong, Ilsan gu, Goyang City, Gyeonggi do 411 706, Korea
Schizophr Res 83:111-9. 2006..These results imply that AH is reflecting increased beta frequency oscillations with neural generators localized in speech-related areas... - Exaggerated affect-modulated startle during unpleasant stimuli in borderline personality disorderErin A Hazlett
Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029, USA
Biol Psychiatry 62:250-5. 2007..The affect-modulated startle response is a reliable indicator of emotional processing of stimuli. The aim of this study was to examine emotional processing in BPD patients (n = 27) and healthy control subjects (n = 21)...