E E Wyckoff

Summary

Affiliation: University of Texas
Country: USA

Publications

  1. pmc HutZ is required for efficient heme utilization in Vibrio cholerae
    Elizabeth E Wyckoff
    Section of Molecular Genetics and Microbiology, The University of Texas at Austin, Austin, Texas 78712 0162, USA
    J Bacteriol 186:4142-51. 2004
  2. pmc Shigella dysenteriae ShuS promotes utilization of heme as an iron source and protects against heme toxicity
    Elizabeth E Wyckoff
    The University of Texas, Section of Molecular Genetics and Microbiology, 1 University Station A5000, Austin, TX 78712 0162, USA
    J Bacteriol 187:5658-64. 2005
  3. pmc Characterization of ferric and ferrous iron transport systems in Vibrio cholerae
    Elizabeth E Wyckoff
    University of Texas, Section of Molecular Genetics and Microbiology, 1 University Station A5000, Austin, TX 78712 0162, USA
    J Bacteriol 188:6515-23. 2006
  4. ncbi request reprint Iron acquisition in Vibrio cholerae
    Elizabeth E Wyckoff
    Section of Molecular Genetics and Microbiology, University of Texas at Austin, 1 University Station A5000, Austin, TX 78712, USA
    Biometals 20:405-16. 2007
  5. pmc A multifunctional ATP-binding cassette transporter system from Vibrio cholerae transports vibriobactin and enterobactin
    E E Wyckoff
    Department of Molecular Genetics and Microbiology, and Institute for Cellular and Molecular Biology, University of Texas, Austin, Texas 78712 1095, USA
    J Bacteriol 181:7588-96. 1999
  6. ncbi request reprint Structure of the Shigella dysenteriae haem transport locus and its phylogenetic distribution in enteric bacteria
    E E Wyckoff
    Department of Microbiology and the Institute for Cellular and Molecular Biology, University of Texas, Austin 78712, USA
    Mol Microbiol 28:1139-52. 1998
  7. pmc The Vibrio cholerae VctPDGC system transports catechol siderophores and a siderophore-free iron ligand
    Elizabeth E Wyckoff
    Section of Molecular Genetics and Microbiology and Institute of Cellular and Molecular Biology, The University of Texas, Austin, TX 78712, USA
    Mol Microbiol 81:1446-58. 2011
  8. ncbi request reprint Vibrio cholerae iron transport: haem transport genes are linked to one of two sets of tonB, exbB, exbD genes
    D A Occhino
    Department of Microbiology and Institute for Cellular and Molecular Biology, University of Texas, Austin 78712, USA
    Mol Microbiol 29:1493-507. 1998
  9. pmc Cloning of a Vibrio cholerae vibriobactin gene cluster: identification of genes required for early steps in siderophore biosynthesis
    E E Wyckoff
    Department of Microbiology, University of Texas, Austin 78712 1095, USA
    J Bacteriol 179:7055-62. 1997
  10. pmc Identification of two Shigella flexneri chromosomal loci involved in intercellular spreading
    M Hong
    Department of Microbiology and Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas 78712, USA
    Infect Immun 66:4700-10. 1998

Collaborators

Detail Information

Publications18

  1. pmc HutZ is required for efficient heme utilization in Vibrio cholerae
    Elizabeth E Wyckoff
    Section of Molecular Genetics and Microbiology, The University of Texas at Austin, Austin, Texas 78712 0162, USA
    J Bacteriol 186:4142-51. 2004
    ..HutZ may act as a heme storage protein, and it may also function as a shuttle protein that increases the efficiency of heme trafficking from the membrane to heme-containing proteins...
  2. pmc Shigella dysenteriae ShuS promotes utilization of heme as an iron source and protects against heme toxicity
    Elizabeth E Wyckoff
    The University of Texas, Section of Molecular Genetics and Microbiology, 1 University Station A5000, Austin, TX 78712 0162, USA
    J Bacteriol 187:5658-64. 2005
    ..ShuS did not appear to store heme for future use...
  3. pmc Characterization of ferric and ferrous iron transport systems in Vibrio cholerae
    Elizabeth E Wyckoff
    University of Texas, Section of Molecular Genetics and Microbiology, 1 University Station A5000, Austin, TX 78712 0162, USA
    J Bacteriol 188:6515-23. 2006
    ..However, a mutant defective in the vibriobactin, Fbp, and Feo systems was not attenuated in a suckling mouse model, suggesting that at least one other iron transport system can be used in vivo...
  4. ncbi request reprint Iron acquisition in Vibrio cholerae
    Elizabeth E Wyckoff
    Section of Molecular Genetics and Microbiology, University of Texas at Austin, 1 University Station A5000, Austin, TX 78712, USA
    Biometals 20:405-16. 2007
    ..The redundancy in iron transport systems has made it more difficult to determine the role of individual systems in vivo and in vitro, but it may reflect the overall importance of iron in the growth and survival of V. cholerae...
  5. pmc A multifunctional ATP-binding cassette transporter system from Vibrio cholerae transports vibriobactin and enterobactin
    E E Wyckoff
    Department of Molecular Genetics and Microbiology, and Institute for Cellular and Molecular Biology, University of Texas, Austin, Texas 78712 1095, USA
    J Bacteriol 181:7588-96. 1999
    ..These mutations reduced, but did not completely eliminate, vibriobactin utilization. This suggests that V. cholerae contains genes in addition to viuPDGC that function in the transport of catechol siderophores...
  6. ncbi request reprint Structure of the Shigella dysenteriae haem transport locus and its phylogenetic distribution in enteric bacteria
    E E Wyckoff
    Department of Microbiology and the Institute for Cellular and Molecular Biology, University of Texas, Austin 78712, USA
    Mol Microbiol 28:1139-52. 1998
    ..dysenteriae, indicating that, in these strains, the haem transport locus has an organization similar to that in S. dysenteriae, and it is located in the same relative position on the chromosome...
  7. pmc The Vibrio cholerae VctPDGC system transports catechol siderophores and a siderophore-free iron ligand
    Elizabeth E Wyckoff
    Section of Molecular Genetics and Microbiology and Institute of Cellular and Molecular Biology, The University of Texas, Austin, TX 78712, USA
    Mol Microbiol 81:1446-58. 2011
    ..We also show that VctPDGC is the previously unidentified siderophore-independent iron transporter in V. cholerae, and this appears to complete the list of iron transport systems in V. cholerae...
  8. ncbi request reprint Vibrio cholerae iron transport: haem transport genes are linked to one of two sets of tonB, exbB, exbD genes
    D A Occhino
    Department of Microbiology and Institute for Cellular and Molecular Biology, University of Texas, Austin 78712, USA
    Mol Microbiol 29:1493-507. 1998
    ..cholerae haem transport system in E. coli. In V. cholerae, the presence of hutBCD stimulated growth when haemin was the iron source, but these genes were not essential for haemin utilization in V. cholerae...
  9. pmc Cloning of a Vibrio cholerae vibriobactin gene cluster: identification of genes required for early steps in siderophore biosynthesis
    E E Wyckoff
    Department of Microbiology, University of Texas, Austin 78712 1095, USA
    J Bacteriol 179:7055-62. 1997
    ..cholerae strain with a chromosomal mutation in vibA was constructed by marker exchange. This strain was unable to produce vibriobactin or DHBA, confirming that in V. cholerae VibA catalyzes an early step in vibriobactin biosynthesis...
  10. pmc Identification of two Shigella flexneri chromosomal loci involved in intercellular spreading
    M Hong
    Department of Microbiology and Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas 78712, USA
    Infect Immun 66:4700-10. 1998
    ..flexneri. The mutant with the insertion at 28 min was interrupted in the same open reading frame as S. flexneri ispA. This ispA mutant could not form plaques and was defective in bacterial septation inside tissue culture cells...
  11. pmc Genetics and virulence association of the Shigella flexneri sit iron transport system
    Carolyn R Fisher
    The University of Texas at Austin, Molecular Genetics and Microbiology, 1 University Station A5000, Austin, TX 78712 0162, USA
    Infect Immun 77:1992-9. 2009
    ..The Sit system is also required for virulence in a mouse lung model. The sitA mutant was able to infect the mice and induce a protective immune response but was avirulent compared to its wild-type parent strain...
  12. pmc Genetics and environmental regulation of Shigella iron transport systems
    Elizabeth E Wyckoff
    Section of Molecular Genetics and Microbiology, Institute for Cellular and Molecular Biology, University of Texas, Austin, TX 78712, USA
    Biometals 22:43-51. 2009
    ..The effects of oxygen are also seen in infection of cultured cells by Shigella flexneri; the Sit and Iuc systems support plaque formation under aerobic conditions, whereas Feo allows plaque formation anaerobically...
  13. pmc Identification of the Vibrio cholerae enterobactin receptors VctA and IrgA: IrgA is not required for virulence
    Alexandra R Mey
    Institute for Cellular and Molecular Biology, The University of Texas, Austin, Texas 78712 1095, USA
    Infect Immun 70:3419-26. 2002
    ..These data indicate that the virulence defect in MBG40 is not due to the loss of irgA function and that irgA is unlikely to be an important virulence factor...
  14. pmc Positive regulation of the Vibrio cholerae porin OmpT by iron and fur
    S A Craig
    Section of Molecular Genetics and Microbiology, Institute for Cellular and Molecular Biology, University of Texas, Austin, TX 78712, USA
    J Bacteriol 193:6505-11. 2011
    ..These data suggest that Fur and iron positively regulate ompT expression through the direct binding of Fur to the ompT promoter...
  15. pmc Vibrio cholerae VciB promotes iron uptake via ferrous iron transporters
    Alexandra R Mey
    The University of Texas at Austin, Section of Molecular Genetics and Microbiology, Austin, TX 78712 1095, USA
    J Bacteriol 190:5953-62. 2008
    ..A V. cholerae vciB mutant did not exhibit any growth defects in either in vitro or in vivo assays, possibly due to the presence of other systems with overlapping functions in this pathogen...
  16. ncbi request reprint Iron and pathogenesis of Shigella: iron acquisition in the intracellular environment
    Shelley M Payne
    Section of Molecular Genetics and Microbiology, The University of Texas at Austin, Austin, TX, 78712, USA
    Biometals 19:173-80. 2006
    ..This regulation is mediated by the repressor protein Fur and the small RNA RyhB...
  17. pmc Iron and fur regulation in Vibrio cholerae and the role of fur in virulence
    Alexandra R Mey
    The University of Texas, Section of Molecular Genetics and Microbiology, Austin, TX 78712 1095, USA
    Infect Immun 73:8167-78. 2005
    ..cholerae. Consistent with this observation, the fur mutant competed poorly with its wild-type parental strain for colonization of the infant mouse gut...
  18. ncbi request reprint Cloning and expression of a gene encoding a T-cell reactive protein from Coccidioides immitis: homology to 4-hydroxyphenylpyruvate dioxygenase and the mammalian F antigen
    E E Wyckoff
    Department of Botany, University of Texas, Austin, 78713, USA
    Gene 161:107-11. 1995
    ..Expression of the Ci tcrP in Escherichia coli resulted in production of a deep brown pigment, consistent with E. coli expression of the bacterial HPPD homolog from Shewanella colwelliana. The TCRP is likely the Ci form of HPPD...