Research Topics
| Ted WunSummaryAffiliation: University of California Country: USA Publications
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Publications
A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell diseaseTed Wun
University of California, Davis Cancer Center, 4501 X St, Ste, 3016, Sacramento, CA, 95817, USA
J Hematol Oncol 6:17. 2013..To evaluate the safety of prasugrel, a thienopyridine antiplatelet agent, in adult patients with SCD, we conducted a double-blind, randomized, placebo-controlled study...
Venous thromboembolism in patients with acute leukemia, lymphoma, and multiple myelomaTed Wun
Division of Hematology and Oncology, UC Davis School of Medicine, Sacramento, CA 95670, USA
Thromb Res 125:S96-102. 2010..Primary and secondary pharmacological prophylaxis can be problematic in these patients who are often thrombocytopenic. Strategies to prevent VTE, especially upper extremity catheter-associated thrombosis need to be developed...- Venous thromboembolism (VTE) in patients with cancer: epidemiology and risk factorsTed Wun
Division of Hematology and Oncology, Department of Internal Medicine, University of California, Davis, California 95187, USA
Cancer Invest 27:63-74. 2009..Development of VTE is clearly associated with decreased survival and this effect is greater among patients initially diagnosed with local or regional stage cancer compared to patients with metastatic cancer... - Cancer Health Empowerment for Living without Pain (Ca-HELP): effects of a tailored education and coaching intervention on pain and impairmentRichard L Kravitz
Department of Internal Medicine and Center for Healthcare Policy and Research, University of California at Davis, Sacramento, CA 95817, USA
Pain 152:1572-82. 2011..10). We conclude that TEC, compared with EUC, resulted in improved pain communication self-efficacy and temporary improvement in pain-related impairment, but no improvement in pain severity... 
Targeting patients for anticoagulant prophylaxis trials in patients with cancer: who is at highest risk?Richard H White
Department of Internal Medicine, University of California, Davis Sacramento, CA, USA
Thromb Res 120:S29-40. 2007..It is not clear which cancer patients are at highest risk for developing venous thromboembolism (VTE)...- Epidemiology of venous thromboembolism in 9489 patients with malignant gliomaThomas J Semrad
Department of Internal Medicine, University of California Davis School of Medicine, Sacramento, California 95817, USA
J Neurosurg 106:601-8. 2007..The authors sought to define the incidence of symptomatic venous thromboembolism (VTE) in patients harboring malignant gliomas... - The incidence of venous thromboembolism and its effect on survival among patients with primary bladder cancerRasanamar Sandhu
Department of Internal Medicine, Division of Hematology Oncology, University of California Davis, Sacramento, California, USA
Cancer 116:2596-603. 2010..The incidence, risk factors, time course, and impact on survival of venous thromboembolism (VTE) in a large, population-based study of patients with bladder cancer have not been identified previously... - Positron emission tomography and improved survival in patients with lung cancer: the Will Rogers phenomenon revisitedKaren G Chee
UC Davis Cancer Center, Sacramento, CA 95817, USA
Arch Intern Med 168:1541-9. 2008..We investigated whether use of highly sensitive positron emission tomography (PET) scanning in non-small cell lung cancer has had this effect... - Venous thromboembolism in patients with acute leukemia: incidence, risk factors, and effect on survivalGrace H Ku
Division of Hematology and Oncology, School of Medicine, University of California San Diego, CA, USA
Blood 113:3911-7. 2009..In the patients with ALL, development of VTE was associated with a 40% increase in the risk of dying within 1 year. The incidence of VTE in acute leukemia is appreciable, and is comparable with the incidence in many solid tumors... - A comparison of multiplex suspension array large-panel kits for profiling cytokines and chemokines in rheumatoid arthritis patientsImran H Khan
Center for Comparative Medicine, University of California, Davis, CA 95616, USA
Cytometry B Clin Cytom 76:159-68. 2009.... - Activated monocytes and platelet-monocyte aggregates in patients with sickle cell diseaseTed Wun
Division of Hematology and Oncology, UC Davis School of Medicine, CA, USA
Clin Lab Haematol 24:81-8. 2002..3 for African-American controls, and 45.7 +/- 21.6 for patients with SCD (P < 0.001, RM ANOVA; P < 0.05, Newman-Keuls posthoc test). We conclude that there are increased circulating PMAs and monocyte activation in patients with SCD... - Comparison of real-time microvascular abnormalities in pediatric and adult sickle cell anemia patientsAnthony T W Cheung
Department of Pathology and Laboratory Medicine, University of California Davis School of Medicine, Sacramento, CA, USA
Am J Hematol 85:899-901. 2010..Intervention and effective treatment/management modalities should target pediatric patients to ameliorate, slow down, or prevent progressive microvascular deterioration... - Venous thromboembolism in ovarian cancerAnne O Rodriguez
Department of Obstetrics and Gynecology, University of California Davis, USA
Gynecol Oncol 105:784-90. 2007..To determine the incidence, time-course, and risk factors associated with the development of thromboembolism (VTE) in a population-based study of women with ovarian cancer... - Microvascular abnormalities in sickle cell disease: a computer-assisted intravital microscopy studyAnthony T W Cheung
Department of Medical Pathology, University of California UC Davis School of Medicine, Davis, CA 95817, USA
Blood 99:3999-4005. 2002..The ability to identify and relocate the same conjunctival vessels for longitudinal studies uniquely underscores the applicability of this quantitative real-time technology... - Evaluation of factors affecting awareness of and willingness to participate in cancer clinical trialsPrimo N Lara
University of California Davis Cancer Center, Sacramento, CA 95817, USA
J Clin Oncol 23:9282-9. 2005..We evaluated the level of awareness of patients and/or their family members/friends regarding CCTs and SB37... - Increased incidence of symptomatic venous thrombosis in patients with cervical carcinoma treated with concurrent chemotherapy, radiation, and erythropoietinTed Wun
Division of Hematology and Oncology, Department of Internal Medicine, University of California Davis School of Medicine, Sacramento, California 95817, USA
Cancer 98:1514-20. 2003..The authors performed a retrospective analysis to determine whether there was an increased rate of symptomatic venous thrombosis associated with the use of rHuEpo in patients with carcinoma of the uterine cervix and vagina... - High-dose radioimmunotherapy combined with fixed, low-dose paclitaxel in metastatic prostate and breast cancer by using a MUC-1 monoclonal antibody, m170, linked to indium-111/yttrium-90 via a cathepsin cleavable linker with cyclosporine to prevent human Carol M Richman
University of California Davis, Sacramento, California 95817, USA
Clin Cancer Res 11:5920-7. 2005..In these phase I studies, paclitaxel was combined with radioimmunotherapy in patients with metastatic hormone-refractory prostate cancer or advanced breast cancer... - Effects of poloxamer 188 treatment on sickle cell vaso-occlusive crisis: computer-assisted intravital microscopy studyAnthony T W Cheung
Departmentsof Pathology and Laboratory Medicine, UC Davis School of Medicine, Davis, CA, USA
J Investig Med 52:402-6. 2004..Further significant improvement induced by poloxamer 188 but not placebo was observed > or = 7 hours postinfusion, resulting in a significant reversal of the microvascular changes to steady-state values... - Risk assessment models for cancer-associated venous thromboembolismMrinal Dutia
Division of Hematology and Oncology, University of California at Davis School of Medicine, University of California at Davis Medical Center, Sacramento, CA 95817, USA
Cancer 118:3468-76. 2012.... - Epidemiology of cancer-related venous thromboembolismTed Wun
Division of Hematology and Oncology, Departments of Internal Medicine and Pathology, Clinical and Translational Sciences Center CTSC, University of California, Davis Cancer Center, 4501 X Street, Sacramento, CA 95187, USA
Best Pract Res Clin Haematol 22:9-23. 2009..Finally, a small percentage of patients with idiopathic VTE and no clinical or laboratory evidence of cancer may harbour an aggressive but 'occult' malignancy likely causally linked to the development of VTE... - Usefulness of optical density values from heparin-platelet factor 4 antibody testing and probability scoring models to diagnose heparin-induced thrombocytopeniaKim A Janatpour
Department of Pathology, University of California, Davis Medical Center, Sacrament, CA 95817, USA
Am J Clin Pathol 127:429-33. 2007..The sensitivity and NPV of the clinical score was improved by incorporating ELISA results. The combination of a negative ELISA result with low probability 4 Ts resulted in an NPV of 94%... - Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS): a 24-year clinical experience with 178 patientsMark Levandovsky
Division of Hematology and Oncology, UC Davis School of Medicine, Sacramento, CA, USA
J Hematol Oncol 1:23. 2008..We performed a retrospective cohort study of 178 consecutively treated patients with TTP-HUS and analyzed whether clinical or laboratory characteristics could predict for important short- and long-term outcome measures... - Overcoming barriers to cancer clinical trial accrual: impact of a mass media campaignAri Umutyan
University of California Davis Cancer Center, Sacramento, California 95817, USA
Cancer 112:212-9. 2008..The authors assessed willingness to participate in and accrual to CCT... - Inflammatory potential of neutrophils detected in sickle cell diseaseAaron F H Lum
Department of Biomedical Engineering, University of California--Davis, Davis, California 95616, USA
Am J Hematol 76:126-33. 2004..These data demonstrate that neutrophils from SCD patients constitutively express active CD18 in blood and respond with enhanced sensitivity to chemokine activation of adhesion, thus increasing their propensity for exuberant adhesion... - Safety and efficacy of rituximab in patients with rheumatoid arthritis refractory to disease modifying antirheumatic drugs and anti-tumor necrosis factor-alpha treatmentJean Higashida
Section of Rheumatology, Veterans Affairs, Northern California Health Care System, Sacramento, California, USA
J Rheumatol 32:2109-15. 2005.... - Cancer Health Empowerment for Living without Pain (Ca-HELP): study design and rationale for a tailored education and coaching intervention to enhance care of cancer-related painRichard L Kravitz
Department of Internal Medicine, University of California Davis, School of Medicine, Sacramento, CA, USA
BMC Cancer 9:319. 2009..Cancer-related pain is common and under-treated. This article describes a study designed to test the effectiveness of a theory-driven, patient-centered coaching intervention to improve cancer pain processes and outcomes... - Venous thromboembolism in patients with colorectal cancer: incidence and effect on survivalAllison Alcalay
Division of Hematology and Oncology, Department of Internal Medicine, University of California, Davis, Sacramento, CA 95817, USA
J Clin Oncol 24:1112-8. 2006..Incident VTE reduced survival among patients with local or regional disease, suggesting that, in these patients, VTE may reflect the presence of a biologically more aggressive cancer... - SU5416 plus interferon alpha in advanced renal cell carcinoma: a phase II California Cancer Consortium Study with biological and imaging correlates of angiogenesis inhibitionPrimo N Lara
University of California Davis Cancer Center, Sacramento, California 95817, USA
Clin Cancer Res 9:4772-81. 2003..Efficacy was correlated with serial plasma VEGF and plasminogen activator inhibitor-1 levels and with positron emission tomography scans... - Low-dose warfarin does not decrease the rate of thrombosis in patients with cervix and vulvo-vaginal cancer treated with chemotherapy, radiation, and erythropoeitinAmy Lin
Department of Internal Medicine, UC Davis School of Medicine, Sacramento, CA 95817, USA
Gynecol Oncol 102:98-102. 2006..83) or lower extremity DVT (P = 0.64). CONCLUSION: Daily low-dose warfarin did not alter the incidence of symptomatic DVT in patients with cervical or vulvo-vaginal cancer who received rHuEpo in conjunction with chemoradiation... - Acetaminophen and diphenhydramine as premedication for platelet transfusions: a prospective randomized double-blind placebo-controlled trialStephen E Wang
Division of Hematology and Oncology, Department of Internal Medicine, UC Davis School of Medicine, Sacramento, California, USA
Am J Hematol 70:191-4. 2002..4% (8/52) in the treatment arm and 15.2% (7/46) in the placebo arm. Premedication prior to transfusion of pre-storage leukocyte reduced SDP does not significantly lower the incidence of NHTR as compared to placebo...