Yvonne Wu

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Erythropoietin for neuroprotection in neonatal encephalopathy: safety and pharmacokinetics
    Yvonne W Wu
    Departments of Neurology, University of California, San Francisco, Child Neurology, 350 Parnassus Ave, Suite 609, San Francisco, CA 94143 0137, USA
    Pediatrics 130:683-91. 2012
  2. pmc Cerebral palsy among Asian ethnic subgroups
    Tess C Lang
    Department of Neurology, University of California San Francisco, San Francisco, CA 94143 0137, USA
    Pediatrics 129:e992-8. 2012
  3. pmc Candidate genes and risk for CP: a population-based study
    Yvonne W Wu
    Department of Neurology, University of California, San Francisco, California 94143, USA
    Pediatr Res 70:642-6. 2011
  4. ncbi request reprint Neuroimaging abnormalities in infants with congenital hemiparesis
    Yvonne W Wu
    Department of Neurology, University of California, San Francisco, California 94143 0137, USA
    Pediatr Neurol 35:191-6. 2006
  5. ncbi request reprint Cerebral palsy in a term population: risk factors and neuroimaging findings
    Yvonne W Wu
    Department of Neurology, University of California, 350 Parnassus Ave, Suite 609, San Francisco, California 94143 0137, USA
    Pediatrics 118:690-7. 2006
  6. ncbi request reprint Ventriculoperitoneal shunt complications in California: 1990 to 2000
    Yvonne Wu
    Department of Neurology, University of California, San Francisco, San Francisco, California 94143 0137, USA
    Neurosurgery 61:557-62; discussion 562-3. 2007
  7. ncbi request reprint Declining diagnosis of birth asphyxia in California: 1991-2000
    Yvonne W Wu
    Department of Neurology, University of California, San Francisco, Box 0136, 500 Parnassus Ave, Room 411, San Francisco, CA 94143 0136, USA
    Pediatrics 114:1584-90. 2004
  8. ncbi request reprint Prognosis for ambulation in cerebral palsy: a population-based study
    Yvonne W Wu
    Department of Neurology, Box 0136, University of California San Francisco, 500 Parnassus Ave, Room 411, San Francisco, CA 94143 0136, USA
    Pediatrics 114:1264-71. 2004
  9. pmc Potential association between infertility and spinal neural tube defects in offspring
    Yvonne W Wu
    Department of Neurology, University of California, San Francisco, California 94143 0137, USA
    Birth Defects Res A Clin Mol Teratol 76:718-22. 2006
  10. doi request reprint Interleukin-6 genotype and risk for cerebral palsy in term and near-term infants
    Yvonne W Wu
    Department of Neurology, University of California, San Francisco, San Francisco, CA 94143 0137, USA
    Ann Neurol 66:663-70. 2009

Research Grants

Detail Information

Publications39

  1. pmc Erythropoietin for neuroprotection in neonatal encephalopathy: safety and pharmacokinetics
    Yvonne W Wu
    Departments of Neurology, University of California, San Francisco, Child Neurology, 350 Parnassus Ave, Suite 609, San Francisco, CA 94143 0137, USA
    Pediatrics 130:683-91. 2012
    ..We hypothesized that high dose Epo would produce plasma concentrations that are neuroprotective in animal studies (ie, maximum concentration = 6000-10000 U/L; area under the curve = 117000-140000 U*h/L)...
  2. pmc Cerebral palsy among Asian ethnic subgroups
    Tess C Lang
    Department of Neurology, University of California San Francisco, San Francisco, CA 94143 0137, USA
    Pediatrics 129:e992-8. 2012
    ..Asians have a reduced risk for cerebral palsy (CP) compared with whites. We examined whether individual Asian subgroups have a reduced risk of CP and whether differences in sociodemographic factors explain disparities in CP prevalence...
  3. pmc Candidate genes and risk for CP: a population-based study
    Yvonne W Wu
    Department of Neurology, University of California, San Francisco, California 94143, USA
    Pediatr Res 70:642-6. 2011
    ..3 versus 13.2%, p = 0.04) were more common in patients with CP than in controls. However, there was no statistically significant association between any genetic polymorphism and CP after correction for multiple comparisons...
  4. ncbi request reprint Neuroimaging abnormalities in infants with congenital hemiparesis
    Yvonne W Wu
    Department of Neurology, University of California, San Francisco, California 94143 0137, USA
    Pediatr Neurol 35:191-6. 2006
    ..001). Neuroimaging studies provide useful diagnostic and prognostic information in infants with congenital hemiparesis...
  5. ncbi request reprint Cerebral palsy in a term population: risk factors and neuroimaging findings
    Yvonne W Wu
    Department of Neurology, University of California, 350 Parnassus Ave, Suite 609, San Francisco, California 94143 0137, USA
    Pediatrics 118:690-7. 2006
    ..The purpose of this work was to study risk factors and neuroimaging characteristics of cerebral palsy in term and near-term infants...
  6. ncbi request reprint Ventriculoperitoneal shunt complications in California: 1990 to 2000
    Yvonne Wu
    Department of Neurology, University of California, San Francisco, San Francisco, California 94143 0137, USA
    Neurosurgery 61:557-62; discussion 562-3. 2007
    ..We examined demographic factors and VP shunt complications in a population-based retrospective cohort study of all nonfederal California hospital admissions between 1990 and 2000...
  7. ncbi request reprint Declining diagnosis of birth asphyxia in California: 1991-2000
    Yvonne W Wu
    Department of Neurology, University of California, San Francisco, Box 0136, 500 Parnassus Ave, Room 411, San Francisco, CA 94143 0136, USA
    Pediatrics 114:1584-90. 2004
    ..Whether advances in perinatal care have altered the incidence of birth asphyxia is unknown. We determined the incidence of birth asphyxia diagnoses made over a 10-year period in California...
  8. ncbi request reprint Prognosis for ambulation in cerebral palsy: a population-based study
    Yvonne W Wu
    Department of Neurology, Box 0136, University of California San Francisco, 500 Parnassus Ave, Room 411, San Francisco, CA 94143 0136, USA
    Pediatrics 114:1264-71. 2004
    ..To determine independent predictors of ambulation among children with cerebral palsy and to develop a simple tool that estimates the probability that a child will walk...
  9. pmc Potential association between infertility and spinal neural tube defects in offspring
    Yvonne W Wu
    Department of Neurology, University of California, San Francisco, California 94143 0137, USA
    Birth Defects Res A Clin Mol Teratol 76:718-22. 2006
    ..We examined the possible association between infertility and spinal neural tube defects (NTDs)...
  10. doi request reprint Interleukin-6 genotype and risk for cerebral palsy in term and near-term infants
    Yvonne W Wu
    Department of Neurology, University of California, San Francisco, San Francisco, CA 94143 0137, USA
    Ann Neurol 66:663-70. 2009
    ..A functional polymorphism in the interleukin-6 (IL-6) gene has been implicated in newborn brain injury. We studied whether the IL-6 -174 G/C polymorphism confers increased risk for CP in term infants...
  11. doi request reprint Nighttime delivery and risk of neonatal encephalopathy
    Yvonne W Wu
    Department of Neurology, University of California School of Medicine, San Francisco, 94117, USA
    Am J Obstet Gynecol 204:37.e1-6. 2011
    ..The objective of the study was to determine the relationship between nighttime delivery and neonatal encephalopathy (NE)...
  12. pmc Racial, ethnic, and socioeconomic disparities in the prevalence of cerebral palsy
    Yvonne W Wu
    Department of Neurology, University of California San Francisco, San Francisco, California 94143 0137, USA
    Pediatrics 127:e674-81. 2011
    ..We determined whether low birth weight accounts for ethnic disparities in the prevalence of cerebral palsy and whether socioeconomic factors impact cerebral palsy within racial and ethnic groups...
  13. doi request reprint Risk factors associated with cerebral palsy in preterm infants
    Andrea Sukhov
    Department of Obstetrics and Gynecology, University of California, Sacramento, CA 95817, USA
    J Matern Fetal Neonatal Med 25:53-7. 2012
    ..To examine pregnancy outcomes in preterm delivered children with cerebral palsy (CP)...
  14. ncbi request reprint JC virus granule cell neuronopathy in a child with CD40 ligand deficiency
    Jonathan H Hecht
    Department of Neurology, University of California, San Francisco, San Francisco, California 94143 0137, USA
    Pediatr Neurol 36:186-9. 2007
    ..JC virus infection should be considered in the differential diagnosis of ataxia in children with inherited immunodeficiencies...
  15. ncbi request reprint Long-term outcomes in patients with treated childhood hydrocephalus
    Nalin Gupta
    Department of Neurological Surgery, University of California, San Francisco 94102, USA
    J Neurosurg 106:334-9. 2007
    ..The goal in this study was to determine the long-term effects of childhood hydrocephalus...
  16. ncbi request reprint Recurrent hemorrhagic stroke in children: a population-based cohort study
    Heather J Fullerton
    Department of Neurology, University of California, San Francisco, Box 0114, San Francisco, CA 94143 0114, USA
    Stroke 38:2658-62. 2007
    ..Although hemorrhagic strokes (HS) account for half of all strokes in children, rates and predictors of recurrent HS have not been studied...
  17. pmc Antenatal and intrapartum risk factors for seizures in term newborns: a population-based study, California 1998-2002
    Hannah C Glass
    Department of Neurology, University of California San Francisco, San Francisco, CA 94143 0663, USA
    J Pediatr 154:24-28.e1. 2009
    ..To assess antenatal and intrapartum risk factors for seizures occurring during the birth admission...
  18. doi request reprint Prevalence and predictors of perinatal hemorrhagic stroke: results from the kaiser pediatric stroke study
    Jennifer Armstrong-Wells
    University of California, Department of Neurology, Box 0114, 505 Parnassus Ave, San Francisco, CA 94143 0114, USA
    Pediatrics 123:823-8. 2009
    ..We sought to determine both the prevalence and predictors of perinatal hemorrhagic stroke within a large, multiethnic population...
  19. pmc The importance of cerebral aneurysms in childhood hemorrhagic stroke: a population-based study
    Lori C Jordan
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Stroke 40:400-5. 2009
    ..Prior population-based studies of pediatric hemorrhagic stroke (HS) had too few incident cases to assess predictors of cerebral aneurysms, a HS etiology that requires urgent intervention...
  20. ncbi request reprint Risk of recurrent childhood arterial ischemic stroke in a population-based cohort: the importance of cerebrovascular imaging
    Heather J Fullerton
    Department of Neurology, University of California, Box 0114, 513 Parnassus Ave, S 784, San Francisco, CA 94143 0114, USA
    Pediatrics 119:495-501. 2007
    ..We sought to establish such rates within a large, multiethnic population and determine whether clinical vascular imaging predicts recurrence...
  21. ncbi request reprint Candidate gene polymorphisms do not differ between newborns with stroke and normal controls
    Steven P Miller
    Department of Neurology, University of California, San Francisco, California, USA
    Stroke 37:2678-83. 2006
    ..Pathways involved in the pathophysiology of neonatal stroke are diverse and may include thrombosis and thrombolysis, vascular reactivity, and inflammation...
  22. ncbi request reprint Multiple risk factors in neonatal sinovenous thrombosis
    Yvonne W Wu
    Department of Neurology, University of California San Francisco, 500 Parnassus Avenue, Rm 412, San Francisco, CA 94143 0136, USA
    Neurology 59:438-40. 2002
    ..Eighteen neonates had multiple maternal, neonatal, perinatal, or prothrombotic complications. Sinovenous thrombosis was often accompanied by infarction (50%) or intraventricular hemorrhage (33%)...
  23. ncbi request reprint Intraventricular hemorrhage in term neonates caused by sinovenous thrombosis
    Yvonne W Wu
    Department of Neurology, University of California, San Francisco, CA 94143 0136, USA
    Ann Neurol 54:123-6. 2003
    ..03). Term neonates with intraventricular hemorrhage should undergo neuroimaging to evaluate the presence of sinovenous thrombosis. Ann Neurol 2003..
  24. ncbi request reprint Risk of stroke in children: ethnic and gender disparities
    Heather J Fullerton
    Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Neurology 61:189-94. 2003
    ..Incidence rates were estimated as the number of first hospitalizations divided by the person-years at risk; case fatality rates were based on in-hospital deaths...
  25. ncbi request reprint Chorioamnionitis and cerebral palsy in term and near-term infants
    Yvonne W Wu
    Department of Neurology, University of California, San Francisco 94143, USA
    JAMA 290:2677-84. 2003
    ..Half of all cases of cerebral palsy (CP) occur in term infants, for whom risk factors have not been clearly defined. Recent studies suggest a possible role of chorioamnionitis...
  26. ncbi request reprint Perinatal outcomes in singletons following in vitro fertilization: a meta-analysis
    Rebecca A Jackson
    Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, 505 Parnassus Avenue, Box 0132, San Francisco, CA 94143, USA
    Obstet Gynecol 103:551-63. 2004
    ....
  27. ncbi request reprint Perinatal stroke in children with motor impairment: a population-based study
    Yvonne W Wu
    Department of Neurology, University of California, San Francisco 94143 0136, USA
    Pediatrics 114:612-9. 2004
    ..Most previous studies lack an appropriate control group and include only infants with symptoms in the newborn period. We set out to determine prenatal and perinatal risk factors for PAS...
  28. ncbi request reprint Maternal and infant characteristics associated with perinatal arterial stroke in the infant
    Janet Lee
    Department of Neurology, University of California, San Francisco, CA 94117, USA
    JAMA 293:723-9. 2005
    ..Perinatal arterial ischemic stroke (PAS) is a common cause of hemiplegic cerebral palsy. Risk factors for this condition have not been clearly defined...
  29. ncbi request reprint Systematic review of chorioamnionitis and cerebral palsy
    Yvonne W Wu
    Department of Neurology, University of California at San Francisco, San Francisco, California 94143 0136, USA
    Ment Retard Dev Disabil Res Rev 8:25-9. 2002
    ..We conclude that based on the available literature, chorioamnionitis is a risk factor for both cerebral palsy and cPVL...
  30. ncbi request reprint Outcomes among newborns with total serum bilirubin levels of 25 mg per deciliter or more
    Thomas B Newman
    Department of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, San Francisco, California, USA
    N Engl J Med 354:1889-900. 2006
    ..The neurodevelopmental risks associated with high total serum bilirubin levels in newborns are not well defined...
  31. ncbi request reprint Remote symptomatic epilepsy: does seizure severity increase mortality?
    David J Strauss
    University of California Life Expectancy Project, San Francisco, USA
    Neurology 60:395-9. 2003
    ..To investigate the excess mortality due to remote symptomatic epilepsy, taking account of frequency and type of seizures...
  32. ncbi request reprint Change in ambulatory ability of adolescents and young adults with cerebral palsy
    Steven M Day
    Life Expectancy Project, San Francisco, CA, USA
    Dev Med Child Neurol 49:647-53. 2007
    ..By age 25 improvement in ambulation is unlikely and decline more likely. Most, however, will not change over the next 15 years...
  33. pmc Imaging data reveal a higher pediatric stroke incidence than prior US estimates
    Nidhi Agrawal
    Department of Pediatrics, University of California, San Francisco, San Francisco, Calif 94143 0114, USA
    Stroke 40:3415-21. 2009
    ..We sought to obtain a new estimate using both diagnostic code searches and searches of radiology reports and to assess the relative value of these 2 strategies...
  34. ncbi request reprint Perinatal arterial stroke: understanding mechanisms and outcomes
    Yvonne W Wu
    Department of Neurology, University of California San Francisco, San Francisco, California 94117, USA
    Semin Neurol 25:424-34. 2005
    ..The incidence, clinical presentation, pathogenesis, risk factors, and outcome of this increasingly recognized disorder are reviewed...
  35. ncbi request reprint Predictors of outcome in perinatal arterial stroke: a population-based study
    Janet Lee
    Department of Neurology, University of California, San Francisco, USA
    Ann Neurol 58:303-8. 2005
    ..4), Wernicke's area (RR, 2.0; 95% CI, 1.1-3.8), or basal ganglia (RR, 1.9; 95% CI, 1.1-3.3). Among infants with PAS, specific radiological findings and a lack of symptoms in the newborn period are associated with increased risk for CP...
  36. pmc Chiari type I malformation in a pediatric population
    Leslie A Aitken
    Department of Pediatrics, University of California San Francisco, San Francisco, CA 94117 0137, USA
    Pediatr Neurol 40:449-54. 2009
    ..Larger and longer-term studies are needed to determine the prognosis and optimal treatment of pediatric Chiari I...
  37. ncbi request reprint Excess mortality in remote symptomatic epilepsy
    Steven Day
    University of California Life Expectancy Project, Department of Pediatrics and Neurology, University of California at San Francisco, USA
    J Insur Med 35:155-60. 2003
    ..This article offers evidence that epilepsy per se is associated with excess mortality. The excess varies according to severity and frequency of seizures...
  38. pmc Five-year neurodevelopmental outcome of neonatal dehydration
    Gabriel J Escobar
    Division of Research, Perinatal Research Unit, Kaiser Permanente Medical Care Program, Oakland, CA 94612, USA
    J Pediatr 151:127-33, 133.e1. 2007
    ..To determine the long-term outcome of neonatal dehydration...
  39. ncbi request reprint Growth patterns in a population of children and adolescents with cerebral palsy
    Steven M Day
    Life Expectancy Project, San Francisco, California, USA Expectancy com
    Dev Med Child Neurol 49:167-71. 2007
    ..The charts may assist in early identification of nutritional or metabolic difficulties beyond what might be expected for patients with similar functional disabilities...

Research Grants2

  1. Inflammation and Cerebral Palsy in Term Infants
    Yvonne Wu; Fiscal Year: 2007
    ..The research plan will also foster the candidate's development as an independent researcher in neuroepidemiology. ..