Research Topics
Species | Yvonne W WuSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Chorioamnionitis as a risk factor for cerebral palsy: A meta-analysisY W Wu
Department of Neurology, University of California, PO Box 0114, San Francisco, CA 94143 0114, USA
JAMA 284:1417-24. 2000..Cystic periventricular leukomalacia (cPVL) is believed to be a precursor of cerebral palsy in preterm infants...- Systematic review of chorioamnionitis and cerebral palsyYvonne W Wu
Department of Neurology, University of California at San Francisco, San Francisco, California 94143 0136, USA
Ment Retard Dev Disabil Res Rev 8:25-9. 2002..We conclude that based on the available literature, chorioamnionitis is a risk factor for both cerebral palsy and cPVL... - Incidence and mortality of generalized convulsive status epilepticus in CaliforniaY W Wu
Department of Neurology, University of California, San Francisco, 94143 0136, USA
Neurology 58:1070-6. 2002..Few population-based studies of status epilepticus have been performed in the United States... - Multiple risk factors in neonatal sinovenous thrombosisYvonne W Wu
Department of Neurology, University of California San Francisco, 500 Parnassus Avenue, Rm 412, San Francisco, CA 94143 0136, USA
Neurology 59:438-40. 2002..Eighteen neonates had multiple maternal, neonatal, perinatal, or prothrombotic complications. Sinovenous thrombosis was often accompanied by infarction (50%) or intraventricular hemorrhage (33%)... 
Cerebral palsy among Asian ethnic subgroupsTess C Lang
Department of Neurology, University of California San Francisco, San Francisco, CA 94143 0137, USA
Pediatrics 129:e992-8. 2012..Asians have a reduced risk for cerebral palsy (CP) compared with whites. We examined whether individual Asian subgroups have a reduced risk of CP and whether differences in sociodemographic factors explain disparities in CP prevalence...- Neuroimaging abnormalities in infants with congenital hemiparesisYvonne W Wu
Department of Neurology, University of California, San Francisco, California 94143 0137, USA
Pediatr Neurol 35:191-6. 2006..001). Neuroimaging studies provide useful diagnostic and prognostic information in infants with congenital hemiparesis... - Outcomes among newborns with total serum bilirubin levels of 25 mg per deciliter or moreThomas B Newman
Department of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, San Francisco, California, USA
N Engl J Med 354:1889-900. 2006..CONCLUSIONS: When treated with phototherapy or exchange transfusion, total serum bilirubin levels in the range included in this study were not associated with adverse neurodevelopmental outcomes in infants born at or near term... - Maternal and infant characteristics associated with perinatal arterial stroke in the infantJanet Lee
Department of Neurology, University of California, San Francisco, CA 94117, USA
JAMA 293:723-9. 2005..How these complications, along with their potential effects on the placenta and fetus, may play a role in causing perinatal stroke deserves further study... - Declining diagnosis of birth asphyxia in California: 1991-2000Yvonne W Wu
Department of Neurology, University of California, San Francisco, Box 0136, 500 Parnassus Ave, Room 411, San Francisco, CA 94143 0136, USA
Pediatrics 114:1584-90. 2004..Whether advances in perinatal care have altered the incidence of birth asphyxia is unknown. We determined the incidence of birth asphyxia diagnoses made over a 10-year period in California... - The importance of cerebral aneurysms in childhood hemorrhagic stroke: a population-based studyLori C Jordan
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Stroke 40:400-5. 2009..Prior population-based studies of pediatric hemorrhagic stroke (HS) had too few incident cases to assess predictors of cerebral aneurysms, a HS etiology that requires urgent intervention... - Risk of recurrent childhood arterial ischemic stroke in a population-based cohort: the importance of cerebrovascular imagingHeather J Fullerton
Department of Neurology, University of California, Box 0114, 513 Parnassus Ave, S 784, San Francisco, CA 94143 0114, USA
Pediatrics 119:495-501. 2007..We sought to establish such rates within a large, multiethnic population and determine whether clinical vascular imaging predicts recurrence... 
Prevalence and predictors of perinatal hemorrhagic stroke: results from the kaiser pediatric stroke studyJennifer Armstrong-Wells
University of California, Department of Neurology, Box 0114, 505 Parnassus Ave, San Francisco, CA 94143 0114, USA
Pediatrics 123:823-8. 2009..We sought to determine both the prevalence and predictors of perinatal hemorrhagic stroke within a large, multiethnic population...- Predictors of outcome in perinatal arterial stroke: a population-based studyJanet Lee
Department of Neurology, University of California, San Francisco, USA
Ann Neurol 58:303-8. 2005..4), Wernicke's area (RR, 2.0; 95% CI, 1.1-3.8), or basal ganglia (RR, 1.9; 95% CI, 1.1-3.3). Among infants with PAS, specific radiological findings and a lack of symptoms in the newborn period are associated with increased risk for CP... - Cerebral palsy in a term population: risk factors and neuroimaging findingsYvonne W Wu
Department of Neurology, University of California, 350 Parnassus Ave, Suite 609, San Francisco, California 94143 0137, USA
Pediatrics 118:690-7. 2006..The purpose of this work was to study risk factors and neuroimaging characteristics of cerebral palsy in term and near-term infants... - Use of the motor performance checklist to study motor outcomes in 5-year-oldsPetra Liljestrand
Departments of Epidemiology and Biostatistics, School of Medicine, University of California, San Francisco, USA
J Paediatr Child Health 45:368-74. 2009..To report findings about the Motor Performance Checklist (MPC) for 5-year-olds, a simple 12-item instrument for assessing gross and fine motor skills, in a research study of neurodevelopmental outcomes after neonatal events... - Prevalence of congenital hydrocephalus in California, 1991-2000Susy Jeng
Division of Child Neurology, University of California at San Francisco, San Francisco, California 94143 0137, USA
Pediatr Neurol 45:67-71. 2011..5, 95% CI 1.4-1.6), and male sex (OR 1.2, 95% CI 1.1-1.3). Asians had a decreased risk for congenital hydrocephalus (OR 0.7, 95% CI 0.6-0.8) when compared to whites. Thirteen percent of affected neonates died before hospital discharge... - Recurrent hemorrhagic stroke in children: a population-based cohort studyHeather J Fullerton
Department of Neurology, University of California, San Francisco, Box 0114, San Francisco, CA 94143 0114, USA
Stroke 38:2658-62. 2007..Although hemorrhagic strokes (HS) account for half of all strokes in children, rates and predictors of recurrent HS have not been studied... - Nighttime delivery and risk of neonatal encephalopathyYvonne W Wu
Department of Neurology, University of California School of Medicine, San Francisco, 94117, USA
Am J Obstet Gynecol 204:37.e1-6. 2011..The objective of the study was to determine the relationship between nighttime delivery and neonatal encephalopathy (NE)... - Perinatal stroke in children with motor impairment: a population-based studyYvonne W Wu
Department of Neurology, University of California, San Francisco 94143 0136, USA
Pediatrics 114:612-9. 2004..Most previous studies lack an appropriate control group and include only infants with symptoms in the newborn period. We set out to determine prenatal and perinatal risk factors for PAS... - Candidate genes and risk for CP: a population-based studyYvonne W Wu
Department of Neurology, University of California, San Francisco, California 94143, USA
Pediatr Res 70:642-6. 2011..3 versus 13.2%, p = 0.04) were more common in patients with CP than in controls. However, there was no statistically significant association between any genetic polymorphism and CP after correction for multiple comparisons... - Imaging data reveal a higher pediatric stroke incidence than prior US estimatesNidhi Agrawal
Department of Pediatrics, University of California, San Francisco, San Francisco, Calif 94143 0114, USA
Stroke 40:3415-21. 2009..We sought to obtain a new estimate using both diagnostic code searches and searches of radiology reports and to assess the relative value of these 2 strategies... - Chiari type I malformation in a pediatric populationLeslie A Aitken
Department of Pediatrics, University of California San Francisco, San Francisco, CA 94117 0137, USA
Pediatr Neurol 40:449-54. 2009..Larger and longer-term studies are needed to determine the prognosis and optimal treatment of pediatric Chiari I... - Excess mortality in remote symptomatic epilepsySteven Day
University of California Life Expectancy Project, Department of Pediatrics and Neurology, University of California at San Francisco, USA
J Insur Med 35:155-60. 2003..This article offers evidence that epilepsy per se is associated with excess mortality. The excess varies according to severity and frequency of seizures... - Interleukin-6 genotype and risk for cerebral palsy in term and near-term infantsYvonne W Wu
Department of Neurology, University of California, San Francisco, San Francisco, CA 94143 0137, USA
Ann Neurol 66:663-70. 2009..A functional polymorphism in the interleukin-6 (IL-6) gene has been implicated in newborn brain injury. We studied whether the IL-6 -174 G/C polymorphism confers increased risk for CP in term infants... - Prognosis for ambulation in cerebral palsy: a population-based studyYvonne W Wu
Department of Neurology, Box 0136, University of California San Francisco, 500 Parnassus Ave, Room 411, San Francisco, CA 94143 0136, USA
Pediatrics 114:1264-71. 2004..To determine independent predictors of ambulation among children with cerebral palsy and to develop a simple tool that estimates the probability that a child will walk... - Change in ambulatory ability of adolescents and young adults with cerebral palsySteven M Day
Life Expectancy Project, San Francisco, CA, USA
Dev Med Child Neurol 49:647-53. 2007..By age 25 improvement in ambulation is unlikely and decline more likely. Most, however, will not change over the next 15 years... - Erythropoietin for neuroprotection in neonatal encephalopathy: safety and pharmacokineticsYvonne W Wu
Departments of Neurology, University of California, San Francisco, Child Neurology, 350 Parnassus Ave, Suite 609, San Francisco, CA 94143 0137, USA
Pediatrics 130:683-91. 2012..We hypothesized that high dose Epo would produce plasma concentrations that are neuroprotective in animal studies (ie, maximum concentration = 6000-10000 U/L; area under the curve = 117000-140000 U*h/L)... - Racial, ethnic, and socioeconomic disparities in the prevalence of cerebral palsyYvonne W Wu
Department of Neurology, University of California San Francisco, San Francisco, California 94143 0137, USA
Pediatrics 127:e674-81. 2011..We determined whether low birth weight accounts for ethnic disparities in the prevalence of cerebral palsy and whether socioeconomic factors impact cerebral palsy within racial and ethnic groups... - Candidate gene polymorphisms do not differ between newborns with stroke and normal controlsSteven P Miller
Department of Neurology, University of California, San Francisco, California, USA
Stroke 37:2678-83. 2006..Pathways involved in the pathophysiology of neonatal stroke are diverse and may include thrombosis and thrombolysis, vascular reactivity, and inflammation... - Antenatal and intrapartum risk factors for seizures in term newborns: a population-based study, California 1998-2002Hannah C Glass
Department of Neurology, University of California San Francisco, San Francisco, CA 94143 0663, USA
J Pediatr 154:24-28.e1. 2009..To assess antenatal and intrapartum risk factors for seizures occurring during the birth admission... - Potential association between infertility and spinal neural tube defects in offspringYvonne W Wu
Department of Neurology, University of California, San Francisco, California 94143 0137, USA
Birth Defects Res A Clin Mol Teratol 76:718-22. 2006..We examined the possible association between infertility and spinal neural tube defects (NTDs)... - Perinatal arterial stroke: understanding mechanisms and outcomesYvonne W Wu
Department of Neurology, University of California San Francisco, San Francisco, California 94117, USA
Semin Neurol 25:424-34. 2005..The incidence, clinical presentation, pathogenesis, risk factors, and outcome of this increasingly recognized disorder are reviewed... - JC virus granule cell neuronopathy in a child with CD40 ligand deficiencyJonathan H Hecht
Department of Neurology, University of California, San Francisco, San Francisco, California 94143 0137, USA
Pediatr Neurol 36:186-9. 2007..JC virus infection should be considered in the differential diagnosis of ataxia in children with inherited immunodeficiencies... - Genetic risk factors for perinatal arterial ischemic strokeAmy A Gelfand
Department of Neurology, University of California at San Francisco, San Francisco, California, USA
Pediatr Neurol 48:36-41. 2013..The apolipoprotein E polymorphism may confer genetic susceptibility for perinatal arterial ischemic stroke. Larger population-based studies are required to confirm this finding... - Risk of stroke in children: ethnic and gender disparitiesHeather J Fullerton
Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
Neurology 61:189-94. 2003..Incidence rates were estimated as the number of first hospitalizations divided by the person-years at risk; case fatality rates were based on in-hospital deaths... - Evidence suggests there was not a "resurgence" of kernicterus in the 1990sJordan C Brooks
Life Expectancy Project, San Francisco, California, USA
Pediatrics 127:672-9. 2011..Although some have suggested that kernicterus disappeared in the United States in the 1970s to 1980s and dramatically reappeared in the 1990s, population-based data to support such a resurgence are lacking... - Chorioamnionitis and cerebral palsy in term and near-term infantsYvonne W Wu
Department of Neurology, University of California, San Francisco 94143, USA
JAMA 290:2677-84. 2003..Half of all cases of cerebral palsy (CP) occur in term infants, for whom risk factors have not been clearly defined. Recent studies suggest a possible role of chorioamnionitis... - Intraventricular hemorrhage in term neonates caused by sinovenous thrombosisYvonne W Wu
Department of Neurology, University of California, San Francisco, CA 94143 0136, USA
Ann Neurol 54:123-6. 2003..03). Term neonates with intraventricular hemorrhage should undergo neuroimaging to evaluate the presence of sinovenous thrombosis. Ann Neurol 2003.. - Long-term outcomes in patients with treated childhood hydrocephalusNalin Gupta
Department of Neurological Surgery, University of California, San Francisco 94102, USA
J Neurosurg 106:334-9. 2007..The goal in this study was to determine the long-term effects of childhood hydrocephalus... - Patterns of brain injury in term neonatal encephalopathySteven P Miller
Department of Neurology, University of California at San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143, USA
J Pediatr 146:453-60. 2005..CONCLUSION: The patterns of brain injury in term neonatal encephalopathy are associated with different clinical presentations and neurodevelopmental outcomes. Measured prenatal risk factors did not predict the pattern of brain injury... - Remote symptomatic epilepsy: does seizure severity increase mortality?David J Strauss
University of California Life Expectancy Project, San Francisco, USA
Neurology 60:395-9. 2003..To investigate the excess mortality due to remote symptomatic epilepsy, taking account of frequency and type of seizures... - Perinatal outcomes in singletons following in vitro fertilization: a meta-analysisRebecca A Jackson
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, 505 Parnassus Avenue, Box 0132, San Francisco, CA 94143, USA
Obstet Gynecol 103:551-63. 2004.... - Five-year neurodevelopmental outcome of neonatal dehydrationGabriel J Escobar
Division of Research, Perinatal Research Unit, Kaiser Permanente Medical Care Program, Oakland, CA 94612, USA
J Pediatr 151:127-33, 133.e1. 2007..To determine the long-term outcome of neonatal dehydration... - Growth patterns in a population of children and adolescents with cerebral palsySteven M Day
Life Expectancy Project, San Francisco, California, USA Expectancy com
Dev Med Child Neurol 49:167-71. 2007..The charts may assist in early identification of nutritional or metabolic difficulties beyond what might be expected for patients with similar functional disabilities...