Yu Wu

Summary

Affiliation: University of Toledo
Country: USA

Publications

  1. ncbi Differential screening identifies transcripts with depot-dependent expression in white adipose tissues
    Yu Wu
    Department of Biochemistry and Cancer Biology, University of Toledo Health Science Campus, Toledo, OH 43614, USA
    BMC Genomics 9:397. 2008
  2. ncbi Expression and regulation of transcript for the novel transmembrane protein Tmem182 in the adipocyte and muscle lineage
    Yu Wu
    Department of Biochemistry and Cancer Biology and Center for Diabetes and Endocrine Research, University of Toledo, Health Science Campus, Toledo, OH 43614, USA
    BMC Res Notes 1:85. 2008
  3. ncbi Assessment of fat-specific protein 27 in the adipocyte lineage suggests a dual role for FSP27 in adipocyte metabolism and cell death
    Ji Young Kim
    Department of Biochemistry and Cancer Biology, University of Toledo Health Science Campus, Toledo, OH 43614, USA
    Am J Physiol Endocrinol Metab 294:E654-67. 2008
  4. ncbi Downregulated expression of the secreted glycoprotein follistatin-like 1 (Fstl1) is a robust hallmark of preadipocyte to adipocyte conversion
    Yu Wu
    Department of Biochemistry and Cancer Biology, Center for Diabetes and Endocrine Research, University of Toledo College of Medicine, Toledo, OH 43614, USA
    Mech Dev 127:183-202. 2010
  5. ncbi Characterization of ScAP-23, a new cell line from murine subcutaneous adipose tissue, identifies genes for the molecular definition of preadipocytes
    Ji Young Kim
    Department of Biochemistry and Cancer Biology, University of Toledo Health Science Campus, Toledo, Ohio 43614, USA
    Physiol Genomics 31:328-42. 2007
  6. ncbi Wdnm1-like, a new adipokine with a role in MMP-2 activation
    Yu Wu
    Department of Biochemistry and Cancer Biology and Center for Diabetes and Endocrine Research, University of Toledo Health Science Campus, Toledo, OH 43614, USA
    Am J Physiol Endocrinol Metab 295:E205-15. 2008
  7. ncbi The major facilitator superfamily member Slc37a2 is a novel macrophage- specific gene selectively expressed in obese white adipose tissue
    Ji Young Kim
    Department of Biochemistry and Cancer Biology, Medical University of Ohio, 3000 Arlington Ave, Toledo, OH 43614, USA
    Am J Physiol Endocrinol Metab 293:E110-20. 2007
  8. ncbi Stomatin-like protein 2 is overexpressed in cancer and involved in regulating cell growth and cell adhesion in human esophageal squamous cell carcinoma
    Liyong Zhang
    National Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Clin Cancer Res 12:1639-46. 2006
  9. ncbi Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis
    Boryana K Popivanova
    Division of Molecular Bioregulation, Cancer Research Institute, Kanazawa University, Kanazawa, Japan
    J Clin Invest 118:560-70. 2008
  10. ncbi Tumor cell apoptosis induces tumor-specific immunity in a CC chemokine receptor 1- and 5-dependent manner in mice
    Noriho Iida
    Cancer Research Institute, Kanazawa University, Kanazawa 920 0934, Japan
    J Leukoc Biol 84:1001-10. 2008

Collaborators

  • Cynthia M Smas
  • Kun Liu
  • W Liu
  • Ji Young Kim
  • Naofumi Mukaida
  • Noriho Iida
  • Boryana K Popivanova
  • Kristin Tillison
  • Shengli Zhou
  • Liyong Zhang
  • Ji-Hong Wang
  • Chifumi Fujii
  • Ying-Yi Li
  • Tomohisa Baba
  • Ying Yi Li
  • Shiuchi Kaneko
  • Shuichi Kaneko
  • Kaheita Kakinoki
  • Masanobu Oshima
  • Takashi Kagaya
  • Toshikazu Kondo
  • Noriho Lida
  • Yasunari Nakamoto
  • Kazuya Kitamura
  • Kouji Matsushima
  • Zhongmin Liu
  • Yanda Li
  • Zhihua Liu
  • Wenfeng Cao
  • Zaicheng Yu
  • Wendong Li
  • Fang Ding
  • Feng Ren
  • Bao-Chang Zhao

Detail Information

Publications13

  1. ncbi Differential screening identifies transcripts with depot-dependent expression in white adipose tissues
    Yu Wu
    Department of Biochemistry and Cancer Biology, University of Toledo Health Science Campus, Toledo, OH 43614, USA
    BMC Genomics 9:397. 2008
    ..To identify such genes, we prepared subtractive cDNA libraries from murine subcutaneous (SC) or intra-abdominal epididymal (EP) white adipocytes...
  2. ncbi Expression and regulation of transcript for the novel transmembrane protein Tmem182 in the adipocyte and muscle lineage
    Yu Wu
    Department of Biochemistry and Cancer Biology and Center for Diabetes and Endocrine Research, University of Toledo, Health Science Campus, Toledo, OH 43614, USA
    BMC Res Notes 1:85. 2008
    ..White adipose tissue is not only an energy storage organ; it also functions as an endocrine organ. The coordination and integration of numerous gene expression events is required to establish and maintain the adipocyte phenotype...
  3. ncbi Assessment of fat-specific protein 27 in the adipocyte lineage suggests a dual role for FSP27 in adipocyte metabolism and cell death
    Ji Young Kim
    Department of Biochemistry and Cancer Biology, University of Toledo Health Science Campus, Toledo, OH 43614, USA
    Am J Physiol Endocrinol Metab 294:E654-67. 2008
    ..This suggests that adipogenesis is accompanied by decreased susceptibility to the proapoptotic effects of FSP27. Overall, our findings support roles for FSP27 in cell death and in adipocyte function...
  4. ncbi Downregulated expression of the secreted glycoprotein follistatin-like 1 (Fstl1) is a robust hallmark of preadipocyte to adipocyte conversion
    Yu Wu
    Department of Biochemistry and Cancer Biology, Center for Diabetes and Endocrine Research, University of Toledo College of Medicine, Toledo, OH 43614, USA
    Mech Dev 127:183-202. 2010
    ..Together, our data suggest downregulation of Fstl1 expression may be an important feature of preadipocyte to adipocyte conversion...
  5. ncbi Characterization of ScAP-23, a new cell line from murine subcutaneous adipose tissue, identifies genes for the molecular definition of preadipocytes
    Ji Young Kim
    Department of Biochemistry and Cancer Biology, University of Toledo Health Science Campus, Toledo, Ohio 43614, USA
    Physiol Genomics 31:328-42. 2007
    ..This suggests that comparative gene expression studies of ScAP-23 and 3T3-L1 adipogenesis may be particularly fruitful in identifying preadipocyte-expressed genes that play a role in adipose tissue physiology and/or pathophysiology...
  6. ncbi Wdnm1-like, a new adipokine with a role in MMP-2 activation
    Yu Wu
    Department of Biochemistry and Cancer Biology and Center for Diabetes and Endocrine Research, University of Toledo Health Science Campus, Toledo, OH 43614, USA
    Am J Physiol Endocrinol Metab 295:E205-15. 2008
    ..We postulate that Wdnm1-like may play roles in remodeling of the extracellular milieu in adipogenesis, as well as in tumor microenvironments where adipocytes are key stromal components...
  7. ncbi The major facilitator superfamily member Slc37a2 is a novel macrophage- specific gene selectively expressed in obese white adipose tissue
    Ji Young Kim
    Department of Biochemistry and Cancer Biology, Medical University of Ohio, 3000 Arlington Ave, Toledo, OH 43614, USA
    Am J Physiol Endocrinol Metab 293:E110-20. 2007
    ..We postulate that the function of this macrophage-specific putative sugar transporter is central to the metabolism of the macrophage population specifically present in obese WAT...
  8. ncbi Stomatin-like protein 2 is overexpressed in cancer and involved in regulating cell growth and cell adhesion in human esophageal squamous cell carcinoma
    Liyong Zhang
    National Laboratory of Molecular Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
    Clin Cancer Res 12:1639-46. 2006
    ..We show here the involvement of SLP-2 in human esophageal squamous cell carcinoma (ESCC), lung cancer, laryngeal cancer, and endometrial adenocarcinoma and the effects of SLP-2 on ESCC cells...
  9. ncbi Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis
    Boryana K Popivanova
    Division of Molecular Bioregulation, Cancer Research Institute, Kanazawa University, Kanazawa, Japan
    J Clin Invest 118:560-70. 2008
    ..These observations identify TNF-alpha as a crucial mediator of the initiation and progression of colitis-associated colon carcinogenesis and suggest that targeting TNF-alpha may be useful in treating colon cancer in individuals with UC...
  10. ncbi Tumor cell apoptosis induces tumor-specific immunity in a CC chemokine receptor 1- and 5-dependent manner in mice
    Noriho Iida
    Cancer Research Institute, Kanazawa University, Kanazawa 920 0934, Japan
    J Leukoc Biol 84:1001-10. 2008
    ....
  11. ncbi [Anti-oxidative effect of ribonuclease inhibitor by site-directed mutagenesis and expression in Pichia pastoris]
    Yu Wu
    College of Life Sciences, Liaoning Normal University, Dalian, China
    Yi Chuan 27:249-54. 2005
    ..The enhance in anti-oxidative effect might be the reason for preventing the formation of disulfide bond between cys328 and cys329 and the three dimensional structure of RI was thereby maintained...
  12. ncbi Cloning and characterization of Adinbitor, a novel disintegrin from the snake venom of Agkistrodon halys brevicaudus stejneger
    Ji-Hong Wang
    Department of Biochemistry and Molecular Biology, Dalian Medical University, Dalian 116027, China
    Acta Biochim Biophys Sin (Shanghai) 36:425-9. 2004
    ..89 microM respectively. Furthermore, Adinbitor significantly inhibited angiogenesis both in vivo and in vitro. Taken together, these results suggested that Adinbitor had typical functions of disintegrins...
  13. ncbi [Investigation on tumor-targeting characteristics of bifidobacterium infantis to melanoma in mice]
    Yu Wu
    Department of Pathophysiology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China
    Sichuan Da Xue Xue Bao Yi Xue Ban 34:435-8. 2003
    ..A large part of area was Gram positive in the tumor tissue section, whereas the normal tissue was Gram negative. CONCLUSION: Bifidobacterium infantis has good tumor-targeting characteristics in mice melanoma...