Research Topics
| Xueling WuSummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
| Collaborators
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Detail Information
Publications
Plasma and salivary IgA subclasses and IgM in HIV-1-infected individualsXueling Wu
Department of Microbiology, University of Alabama at Birmingham, 35294 2170, USA
J Clin Immunol 22:106-15. 2002....
A longitudinal study of plasma and salivary antibodies in HIV-1 infectionXueling Wu
Department of Microbiology, University of Alabama at Birmingham, 35294 2170, USA
Viral Immunol 15:325-35. 2002..The binding intensities of plasma and salivary IgA antibodies specific for certain viral proteins were associated with plasma viral load in some subjects as well...
Soluble CD4 broadens neutralization of V3-directed monoclonal antibodies and guinea pig vaccine sera against HIV-1 subtype B and C reference virusesXueling Wu
Vaccine Research Center, NIAID, NIH, Bethesda, MD 20892, USA
Virology 380:285-95. 2008..These findings confirm that V3 antibodies recognize most primary viral strains, but that the epitope often has limited accessibility in the context of native envelope spike...
Tropism-restricted neutralization by secretory IgA from parotid saliva of HIV type 1-infected individualsXueling Wu
Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
AIDS Res Hum Retroviruses 19:275-81. 2003....
Increased levels of galactose-deficient IgG in sera of HIV-1-infected individualsJennifer S Moore
Department of Microbiology, University of Alabama at Birmingham, Birmingham, Alabama, USA
AIDS 19:381-9. 2005..However, this phenomenon has not been investigated at length in human viral infections...
The infectious molecular clone and pseudotyped virus models of human immunodeficiency virus type 1 exhibit significant differences in virion composition with only moderate differences in infectivity and inhibition sensitivityNicholas M Provine
Department of Microbiology, University of Washington, Seattle, Washington 98195, USA
J Virol 83:9002-7. 2009..Differences in Env incorporation and cleavage translated into moderate differences in assays infectivity and sensitivity to neutralizing antibodies and entry inhibitors...
Neutralization escape variants of human immunodeficiency virus type 1 are transmitted from mother to infantXueling Wu
Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N, Seattle, WA 98109-1024, USA
J Virol 80:835-44. 2006....
Cloning and characterization of functional subtype A HIV-1 envelope variants transmitted through breastfeedingStephanie M J Rainwater
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 0124, USA
Curr HIV Res 5:189-97. 2007....
Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect antibody neutralization sensitivityManish Sagar
Department of Medicine, Brigham and Women's Hospital, Cambridge, Massachusetts 02139, USA
J Virol 80:9586-98. 2006..These studies suggest that changes within the V1-V2 envelope domains over the course of an infection influence sensitivity to autologous neutralizing antibodies and may also impact host receptor/coreceptor interactions...
Broad HIV-1 neutralization mediated by CD4-binding site antibodiesYuxing Li
Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
Nat Med 13:1032-4. 2007..Novel antibodies to the CD4-binding site are elicited in some HIV-1-infected individuals, and new approaches to present this conserved region of gp120 to the immune system may result in improved vaccine immunogens...
Heavily glycosylated, highly fit SIVMne variants continue to diversify and undergo selection after transmission to a new host and they elicit early antibody dependent cellular responses but delayed neutralizing antibody responsesDawnnica Eastman
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Virol J 5:90. 2008..To begin to address this, we analyzed the envelope sequence variation of viruses that evolved in animals infected with variants of SIVMne that had been cloned from an index animal at different stages of infection...
