Xianli Wu

Summary

Affiliation: University of Arkansas for Medical Sciences
Country: USA

Publications

  1. doi request reprint Dietary blueberries attenuate atherosclerosis in apolipoprotein E-deficient mice by upregulating antioxidant enzyme expression
    Xianli Wu
    USDA Arkansas Children s Nutrition Center, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA
    J Nutr 140:1628-32. 2010
  2. doi request reprint Lipid fatty acid profile analyses in liver and serum in rats with nonalcoholic steatohepatitis using improved gas chromatography-mass spectrometry methodology
    Xianli Wu
    Arkansas Children s Nutrition Center, University of Arkansas for Medical Sciences, 15 Children s Way, Little Rock, Arkansas 72202, United States
    J Agric Food Chem 59:747-54. 2011
  3. doi request reprint Dietary-induced serum phenolic acids promote bone growth via p38 MAPK/β-catenin canonical Wnt signaling
    Jin Ran Chen
    Arkansas Children s Nutrition Center, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA
    J Bone Miner Res 25:2399-411. 2010
  4. doi request reprint Purified berry anthocyanins but not whole berries normalize lipid parameters in mice fed an obesogenic high fat diet
    Ronald L Prior
    United States Department of Agriculture, Little Rock, AR, USA
    Mol Nutr Food Res 53:1406-18. 2009
  5. pmc Differential effects of short term feeding of a soy protein isolate diet and estrogen treatment on bone in the pre-pubertal rat
    Jian Zhang
    Arkansas Children s Nutrition Center, Little Rock, Arkansas, United States of America
    PLoS ONE 7:e35736. 2012
  6. doi request reprint Purified blueberry anthocyanins and blueberry juice alter development of obesity in mice fed an obesogenic high-fat diet
    Ronald L Prior
    Agriculture Research Service, U S Department of Agriculture, Arkansas Children s Nutrition Center, Little Rock, Arkansas 72202, USA
    J Agric Food Chem 58:3970-6. 2010
  7. ncbi request reprint Dietary rice protein isolate attenuates atherosclerosis in apoE-deficient mice by upregulating antioxidant enzymes
    Ramona L Burris
    Arkansas Children s Nutrition Center, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA
    Atherosclerosis 212:107-15. 2010
  8. doi request reprint Lowbush blueberries inhibit scavenger receptors CD36 and SR-A expression and attenuate foam cell formation in ApoE-deficient mice
    Chenghui Xie
    USDA Arkansas Children s Nutrition Center, Little Rock, AR 72202, USA
    Food Funct 2:588-94. 2011
  9. doi request reprint Açaí juice attenuates atherosclerosis in ApoE deficient mice through antioxidant and anti-inflammatory activities
    Chenghui Xie
    USDA Arkansas Children s Nutrition Center, University of Arkansas for Medical Sciences, 15 Children s Way, Little Rock, AR 72202, USA
    Atherosclerosis 216:327-33. 2011
  10. ncbi request reprint Concentrations of anthocyanins in common foods in the United States and estimation of normal consumption
    Xianli Wu
    USDA Arkansas Children s Nutrition Center, 1120 Marshall Street, Little Rock, Arkansas 72202, USA
    J Agric Food Chem 54:4069-75. 2006

Detail Information

Publications37

  1. doi request reprint Dietary blueberries attenuate atherosclerosis in apolipoprotein E-deficient mice by upregulating antioxidant enzyme expression
    Xianli Wu
    USDA Arkansas Children s Nutrition Center, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA
    J Nutr 140:1628-32. 2010
    ..The potential mechanisms may involve reduction in oxidative stress by both inhibition of lipid peroxidation and enhancement of antioxidant defense...
  2. doi request reprint Lipid fatty acid profile analyses in liver and serum in rats with nonalcoholic steatohepatitis using improved gas chromatography-mass spectrometry methodology
    Xianli Wu
    Arkansas Children s Nutrition Center, University of Arkansas for Medical Sciences, 15 Children s Way, Little Rock, Arkansas 72202, United States
    J Agric Food Chem 59:747-54. 2011
    ..Alteration of FA composition in liver after overfeeding of high polyunsaturated fat diets may contribute to the progression of pathological changes from steatosis to inflammation, necrosis, and fibrosis observed in NASH...
  3. doi request reprint Dietary-induced serum phenolic acids promote bone growth via p38 MAPK/β-catenin canonical Wnt signaling
    Jin Ran Chen
    Arkansas Children s Nutrition Center, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA
    J Bone Miner Res 25:2399-411. 2010
    ....
  4. doi request reprint Purified berry anthocyanins but not whole berries normalize lipid parameters in mice fed an obesogenic high fat diet
    Ronald L Prior
    United States Department of Agriculture, Little Rock, AR, USA
    Mol Nutr Food Res 53:1406-18. 2009
    ....
  5. pmc Differential effects of short term feeding of a soy protein isolate diet and estrogen treatment on bone in the pre-pubertal rat
    Jian Zhang
    Arkansas Children s Nutrition Center, Little Rock, Arkansas, United States of America
    PLoS ONE 7:e35736. 2012
    ..However, mechanistic studies comparing the effects of soy diet and estrogens on bone, particularly in rapidly growing animals are lacking...
  6. doi request reprint Purified blueberry anthocyanins and blueberry juice alter development of obesity in mice fed an obesogenic high-fat diet
    Ronald L Prior
    Agriculture Research Service, U S Department of Agriculture, Arkansas Children s Nutrition Center, Little Rock, Arkansas 72202, USA
    J Agric Food Chem 58:3970-6. 2010
    ..Additional studies are needed to determine factors responsible for the differing responses of blueberry juice and whole blueberry in preventing the development of obesity...
  7. ncbi request reprint Dietary rice protein isolate attenuates atherosclerosis in apoE-deficient mice by upregulating antioxidant enzymes
    Ramona L Burris
    Arkansas Children s Nutrition Center, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA
    Atherosclerosis 212:107-15. 2010
    ....
  8. doi request reprint Lowbush blueberries inhibit scavenger receptors CD36 and SR-A expression and attenuate foam cell formation in ApoE-deficient mice
    Chenghui Xie
    USDA Arkansas Children s Nutrition Center, Little Rock, AR 72202, USA
    Food Funct 2:588-94. 2011
    ..We proposed that BB mediated reduction of scavenger receptor expression and attenuation of oxLDL-induced foam cell formation in PM of apoE(-/-) mice are important mechanisms of the athero-protective effects of BB...
  9. doi request reprint Açaí juice attenuates atherosclerosis in ApoE deficient mice through antioxidant and anti-inflammatory activities
    Chenghui Xie
    USDA Arkansas Children s Nutrition Center, University of Arkansas for Medical Sciences, 15 Children s Way, Little Rock, AR 72202, USA
    Atherosclerosis 216:327-33. 2011
    ..In this study, athero-protective effects of açaí juice were investigated in apolipoprotein E deficient (apoE(-/-)) mice...
  10. ncbi request reprint Concentrations of anthocyanins in common foods in the United States and estimation of normal consumption
    Xianli Wu
    USDA Arkansas Children s Nutrition Center, 1120 Marshall Street, Little Rock, Arkansas 72202, USA
    J Agric Food Chem 54:4069-75. 2006
    ..Of the different aglycones, cyanidin, delphinidin, and malvidin were estimated to contribute 45, 21, and 15%, respectively, of the total ACN intake. Nonacylated contributed 77% compared to 23% from acylated ACNs...
  11. doi request reprint Whole berries versus berry anthocyanins: interactions with dietary fat levels in the C57BL/6J mouse model of obesity
    Ronald L Prior
    USDA Arkansas Children s Nutrition Center, 1212 Marshall Street, Little Rock, Arkansas 72202, USA
    J Agric Food Chem 56:647-53. 2008
    ..Anthocyanins fed as the whole blueberry did not prevent and may have actually increased obesity. However, feeding purified anthocyanins from blueberries or strawberries reduced obesity...
  12. ncbi request reprint Fate of anthocyanins and antioxidant capacity in contents of the gastrointestinal tract of weanling pigs following black raspberry consumption
    Xianli Wu
    Arkansas Children s Nutrition Center, Agriculture Research Service, U S Department of Agriculture, 1120 Marshall Street, Little Rock, Arkansas 72202, USA
    J Agric Food Chem 54:583-9. 2006
    ..TAC and total ACNs remained high 4 h after feeding, which indicates that ACNs provide significant antioxidant protection in the environment of the gut epithelium...
  13. doi request reprint Phenolic acids are in vivo atheroprotective compounds appearing in the serum of rats after blueberry consumption
    Chenghui Xie
    USDA Arkansas Children s Nutrition Center, Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, 15 Children s Way, Little Rock, Arkansas 72202, United States
    J Agric Food Chem 59:10381-7. 2011
    ..Because BB contain many phytochemicals, other as yet unidentified bioactive compounds may also be important in preventing atherosclerosis in this model and, possibly, in humans...
  14. doi request reprint Blueberries reduce pro-inflammatory cytokine TNF-α and IL-6 production in mouse macrophages by inhibiting NF-κB activation and the MAPK pathway
    Chenghui Xie
    USDA Arkansas Children s Nutrition Center, Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, 15 Chuldren s Way, Little Rock, AR 72202, USA
    Mol Nutr Food Res 55:1587-91. 2011
    ..Furthermore, SEB inhibited the phosphorylation of IκB, NF-κB p65, MAPK p38 and JNK. All of these are important signaling pathways involved in the production of TNF-α and IL-6...
  15. ncbi request reprint Aglycones and sugar moieties alter anthocyanin absorption and metabolism after berry consumption in weanling pigs
    Xianli Wu
    U S Department of Agriculture, Agriculture Research Service, Arkansas Children s Nutrition Center, Little Rock, AR 72202, USA
    J Nutr 135:2417-24. 2005
    ..The data clearly demonstrate that the aglycone and the sugar moieties can alter the apparent absorption and metabolism of ACNs...
  16. doi request reprint Phenolic acids in black raspberry and in the gastrointestinal tract of pigs following ingestion of black raspberry
    Xianli Wu
    USDA Arkansas Children s Nutrition Center, University of Arkansas for Medical Sciences, AR, USA
    Mol Nutr Food Res 53:S76-84. 2009
    ..49 +/- 4.31 micromol (homoprotocatechuic acid). Total phenolic acids in the GI tract were 49.32 +/- 16.37 micromol (mean +/- SEM, n = 5). Phenolic acids measured in the GI tract accounted for only 6.31% of the degraded anthocyanins...
  17. ncbi request reprint Plasma antioxidant capacity changes following a meal as a measure of the ability of a food to alter in vivo antioxidant status
    Ronald L Prior
    USDA Arkansas Children s Nutrition Center, Little Rock, AR 72202, USA
    J Am Coll Nutr 26:170-81. 2007
    ....
  18. doi request reprint In utero and lactational exposure to blueberry via maternal diet promotes mammary epithelial differentiation in prepubescent female rats
    Xianli Wu
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA
    Nutr Res 29:802-11. 2009
    ..Our studies identify developing mammary glands as early targets of blueberry-associated bioactive components, possibly through systemic effects on epithelial PTEN signaling...
  19. doi request reprint Medium chain triglycerides dose-dependently prevent liver pathology in a rat model of non-alcoholic fatty liver disease
    Martin J J Ronis
    Arkansas Children s Nutrition Center, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA
    Exp Biol Med (Maywood) 238:151-62. 2013
    ..These data suggest that replacing unsaturated fats like corn oil with MCT oil in the diet could be utilized as a potential treatment for NAFLD...
  20. doi request reprint The açaí flavonoid velutin is a potent anti-inflammatory agent: blockade of LPS-mediated TNF-α and IL-6 production through inhibiting NF-κB activation and MAPK pathway
    Chenghui Xie
    USDA Arkansas Children s Nutrition Center, Little Rock, AR 72202, USA
    J Nutr Biochem 23:1184-91. 2012
    ..This compound effectively inhibited the expression of proinflammatory cytokines TNF-α and IL-6 in low micromole levels by inhibiting NF-κB activation and p38 and JNK phosphorylation...
  21. ncbi request reprint Lipophilic and hydrophilic antioxidant capacities of common foods in the United States
    Xianli Wu
    Arkansas Children s Nutrition Center and Agricultural Research Service, U S Department of Agriculture, 1120 Marshall Street, Little Rock, Arkansas 72202, USA
    J Agric Food Chem 52:4026-37. 2004
    ..Total hydrophilic and lipophilic antioxidant capacity intakes were calculated to be 5558 and 166 micromol of TE/day, respectively, on the basis of data from the USDA Continuing Survey of Food Intakes by Individuals (1994-1996)...
  22. ncbi request reprint Standardized methods for the determination of antioxidant capacity and phenolics in foods and dietary supplements
    Ronald L Prior
    U S Department of Agriculture, Arkansas Children s Nutrition Center, 1120 Marshall Street, Little Rock, Arkansas 72202, USA
    J Agric Food Chem 53:4290-302. 2005
    ..The TEAC assay represents a second ET-based method. Other assays may need to be considered in the future as more is learned about some of the other radical sources and their importance to human biology...
  23. pmc Obesity reduces bone density associated with activation of PPARγ and suppression of Wnt/β-catenin in rapidly growing male rats
    Jin Ran Chen
    Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America
    PLoS ONE 5:e13704. 2010
    ..It is well established that excessive consumption of a high fat diet (HFD) results in obesity; however, the consequences of obesity on postnatal skeletal development have not been well studied...
  24. ncbi request reprint Procyanidin and catechin contents and antioxidant capacity of cocoa and chocolate products
    Liwei Gu
    Arkansas Children s Nutrition Center, ARS USDA, and Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72202, USA
    J Agric Food Chem 54:4057-61. 2006
    ..These results indicate that NFCS is correlated with AOC and PC in cocoa and chocolate products. Alkalizing dramatically decreased both the procyanidin content and antioxidant capacity, although not to the same extent...
  25. doi request reprint Repression of mammosphere formation of human breast cancer cells by soy isoflavone genistein and blueberry polyphenolic acids suggests diet-mediated targeting of cancer stem-like/progenitor cells
    Maria Theresa E Montales
    Arkansas Children s Nutrition Center, 15 Children s Way, Little Rock, AR 72202, USA
    Carcinogenesis 33:652-60. 2012
    ..These findings delineate a novel and selective function of distinct dietary factors in targeting stem/progenitor cell populations in estrogen receptor-dependent and -independent breast cancers...
  26. ncbi request reprint Systematic identification and characterization of anthocyanins by HPLC-ESI-MS/MS in common foods in the United States: fruits and berries
    Xianli Wu
    Agriculture Research Service, U S Department of Agriculture, Arkansas Children s Nutrition Center, 1120 Marshall Street, Little Rock, Arkansas 72202, USA
    J Agric Food Chem 53:2589-99. 2005
    ..For the first time, this paper presents complete anthocyanin HPLC profiles and MS spectral data of common fruits using the same uniform experimental conditions...
  27. ncbi request reprint Characterization of anthocyanins and proanthocyanidins in some cultivars of Ribes, Aronia, and Sambucus and their antioxidant capacity
    Xianli Wu
    Agriculture Research Service, U S Department of Agriculture, Arkansas Children s Nutrition Center, 1120 Marshall Street, Little Rock, Arkansas 72202, USA
    J Agric Food Chem 52:7846-56. 2004
    ..The total antioxidant capacity varied from 21 micromol of TE/g of FW in Careless gooseberry to 161 micromol of TE/g of FW in chokeberry. Total phenolics in the berries in general paralleled hydrophilic antioxidant capacity...
  28. ncbi request reprint Non-isoflavone phytochemicals in soy and their health effects
    Jie Kang
    USDA Arkansas Children s Nutrition Center, University of Arkansas for Medical Sciences, Little Rock, AR 72202, USA
    J Agric Food Chem 58:8119-33. 2010
    ..This review attempts to summarize major non-isoflavone phytochemicals in soy, as well as their bioavailability and health effects. In addition, a brief discussion of components formed during food processing is also included...
  29. ncbi request reprint Identification and urinary excretion of metabolites of 5-(hydroxymethyl)-2-furfural in human subjects following consumption of dried plums or dried plum juice
    Ronald L Prior
    U S Department of Agriculture, Agriculture Research Service, Arkansas Children s Nutrition Center, 1120 Marshall Street, Little Rock, Arkansas 72202, USA
    J Agric Food Chem 54:3744-9. 2006
    ..2% and 14.2% of the I dose during the first 6 h after consumption of dried plum juice and dried plums, respectively. I seems to be metabolized rapidly to glycine conjugates and other metabolites and excreted in the urine...
  30. ncbi request reprint Anthocyanins: structural characteristics that result in unique metabolic patterns and biological activities
    Ronald L Prior
    Arkansas Children s Nutrition Center, 1120 Marshall Street, Little Rock, AR 72202, USA
    Free Radic Res 40:1014-28. 2006
    ..Anthocyanins may play an important role in health promotion in terms of obesity prevention, cardiovascular health, anti-inflammatory and anti-cancer effects...
  31. ncbi request reprint Identification and characterization of anthocyanins by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry in common foods in the United States: vegetables, nuts, and grains
    Xianli Wu
    Arkansas Children s Nutrition Center, Agriculture Research Service, U S Department of Agriculture, 1120 Marshall Street, Little Rock, Arkansas 72202, USA
    J Agric Food Chem 53:3101-13. 2005
    ..This paper presents complete HPLC profiles and MS spectrometric data, obtained under the same experimental conditions, for common vegetables, pistachio nuts, and sorghum that contain anthocyanins...
  32. doi request reprint Urinary excretion of phenolic acids in rats fed cranberry
    Ronald L Prior
    USDA ARS, USA
    J Agric Food Chem 58:3940-9. 2010
    ....
  33. doi request reprint Dietary black raspberry anthocyanins do not alter development of obesity in mice fed an obesogenic high-fat diet
    Ronald L Prior
    USDA ARS, USA
    J Agric Food Chem 58:3977-83. 2010
    ..The sugar moiety on the anthocyanidins may be an important factor in determining the response in the development of obesity...
  34. pmc Lack of efficacy of blueberry in nutritional prevention of azoxymethane-initiated cancers of rat small intestine and colon
    Frank A Simmen
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, 4301 W Markham Street, Little Rock, AR 72205, USA
    BMC Gastroenterol 9:67. 2009
    ..Previous work indicated an inhibitory effect of consumed blueberry (BB) on formation of aberrant crypt foci (ACF) in colons of male Fisher F344 rats (inbred strain). However, effects of BB on colon tumors and in both genders are unknown...
  35. ncbi request reprint Assays for hydrophilic and lipophilic antioxidant capacity (oxygen radical absorbance capacity (ORAC(FL))) of plasma and other biological and food samples
    Ronald L Prior
    U S Department of Agriculture, Agriculture Research Service, Arkansas, Children s Nutrition Center, 1120 Marshall Street, Little Rock, Arkansas 72202, USA
    J Agric Food Chem 51:3273-9. 2003
    ..9% of the total antioxidant capacity of the protein free plasma in two independent studies of 6 and 10 subjects, respectively. Methods are described for application of the assay techniques to other types of biological and food samples...
  36. doi request reprint Mitigation of inflammation with foods
    Xianli Wu
    USDA Arkansas Children s Nutrition Center, Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, 15 Children s Way, Little Rock, Arkansas 72202, United States
    J Agric Food Chem 60:6703-17. 2012
    ....
  37. ncbi request reprint Pelargonidin is absorbed and metabolized differently than cyanidin after marionberry consumption in pigs
    Xianli Wu
    U S Department of Agriculture, Agriculture Research Service, Arkansas Children s Nutrition Center, Little Rock, AR 72202, USA
    J Nutr 134:2603-10. 2004
    ..Urinary recovery of the acylated anthocyanin was lower than that of nonacylated anthocyanins...