Tong Wu

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint A schema for histologic grading of small intestine allograft acute rejection
    Tong Wu
    Department of Pathology, Thomas E Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Transplantation 75:1241-8. 2003
  2. ncbi request reprint Involvement of p38 and p42/44 MAP kinases and protein kinase C in the interferon-gamma and interleukin-1alpha-induced phosphorylation of 85-kDa cytosolic phospholipase A(2) in primary human bronchial epithelial cells
    Tong Wu
    Department of Pathology, University of Pittsburgh School of Medicine, Presbyterian University Hospital C902, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Cytokine 25:11-20. 2004
  3. ncbi request reprint Involvement of 85-kd cytosolic phospholipase A(2) and cyclooxygenase-2 in the proliferation of human cholangiocarcinoma cells
    Tong Wu
    Department of Pathology, University of Pittsburgh School of Medicine, Presbyterian University Hospital, PA 15213, USA
    Hepatology 36:363-73. 2002
  4. ncbi request reprint The cyclooxygenase-2 inhibitor celecoxib blocks phosphorylation of Akt and induces apoptosis in human cholangiocarcinoma cells
    Tong Wu
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Mol Cancer Ther 3:299-307. 2004
  5. ncbi request reprint Prostaglandin E2 receptor EP1 transactivates EGFR/MET receptor tyrosine kinases and enhances invasiveness in human hepatocellular carcinoma cells
    Chang Han
    Department of Pathology, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA
    J Cell Physiol 207:261-70. 2006
  6. ncbi request reprint Transforming growth factor-beta (TGF-beta) activates cytosolic phospholipase A2alpha (cPLA2alpha)-mediated prostaglandin E2 (PGE)2/EP1 and peroxisome proliferator-activated receptor-gamma (PPAR-gamma)/Smad signaling pathways in human liver cancer cells. A
    Chang Han
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Biol Chem 279:44344-54. 2004
  7. ncbi request reprint Cross-talk between peroxisome proliferator-activated receptor delta and cytosolic phospholipase A(2)alpha/cyclooxygenase-2/prostaglandin E(2) signaling pathways in human hepatocellular carcinoma cells
    Lihong Xu
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Cancer Res 66:11859-68. 2006
  8. ncbi request reprint Cyclooxygenase-2 promotes hepatocellular carcinoma cell growth through Akt activation: evidence for Akt inhibition in celecoxib-induced apoptosis
    Jing Leng
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Hepatology 38:756-68. 2003
  9. ncbi request reprint 85-kDa cytosolic phospholipase A2 mediates peroxisome proliferator-activated receptor gamma activation in human lung epithelial cells
    Rafal Pawliczak
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Biol Chem 277:33153-63. 2002
  10. doi request reprint Evolution of the immunosuppressive strategies for the intestinal and multivisceral recipients with special reference to allograft immunity and achievement of partial tolerance
    Kareem M Abu-Elmagd
    Intestinal Rehabilitation and Transplantation Center, Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, PA, USA
    Transpl Int 22:96-109. 2009

Detail Information

Publications58

  1. ncbi request reprint A schema for histologic grading of small intestine allograft acute rejection
    Tong Wu
    Department of Pathology, Thomas E Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Transplantation 75:1241-8. 2003
    ..The primary goal of this study was to develop a histologic grading system for the diagnosis of small bowel allograft acute rejection...
  2. ncbi request reprint Involvement of p38 and p42/44 MAP kinases and protein kinase C in the interferon-gamma and interleukin-1alpha-induced phosphorylation of 85-kDa cytosolic phospholipase A(2) in primary human bronchial epithelial cells
    Tong Wu
    Department of Pathology, University of Pittsburgh School of Medicine, Presbyterian University Hospital C902, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Cytokine 25:11-20. 2004
    ..These results demonstrate the involvement of p38 and p42/44 MAPKs as well as PKC in the IFN-gamma and IL-1alpha-induced cPLA(2) phosphorylation and AA release in human airway epithelial cells...
  3. ncbi request reprint Involvement of 85-kd cytosolic phospholipase A(2) and cyclooxygenase-2 in the proliferation of human cholangiocarcinoma cells
    Tong Wu
    Department of Pathology, University of Pittsburgh School of Medicine, Presbyterian University Hospital, PA 15213, USA
    Hepatology 36:363-73. 2002
    ..In conclusion, molecular pathways link classic biliary epithelial cell mitogens to PG metabolism constituents in cholangiocarcinoma growth, which may be exploited as potential therapeutic targets...
  4. ncbi request reprint The cyclooxygenase-2 inhibitor celecoxib blocks phosphorylation of Akt and induces apoptosis in human cholangiocarcinoma cells
    Tong Wu
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Mol Cancer Ther 3:299-307. 2004
    ..These findings suggest that celecoxib inhibits cholangiocarcinoma growth partly through induction of apoptosis and inhibition of Akt phosphorylation...
  5. ncbi request reprint Prostaglandin E2 receptor EP1 transactivates EGFR/MET receptor tyrosine kinases and enhances invasiveness in human hepatocellular carcinoma cells
    Chang Han
    Department of Pathology, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA
    J Cell Physiol 207:261-70. 2006
    ..These findings disclose a cross-talk between the COX-2/PGE(2)/EP(1) and EGFR/c-Met signaling pathways that coordinately regulate human HCC cell invasion...
  6. ncbi request reprint Transforming growth factor-beta (TGF-beta) activates cytosolic phospholipase A2alpha (cPLA2alpha)-mediated prostaglandin E2 (PGE)2/EP1 and peroxisome proliferator-activated receptor-gamma (PPAR-gamma)/Smad signaling pathways in human liver cancer cells. A
    Chang Han
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Biol Chem 279:44344-54. 2004
    ....
  7. ncbi request reprint Cross-talk between peroxisome proliferator-activated receptor delta and cytosolic phospholipase A(2)alpha/cyclooxygenase-2/prostaglandin E(2) signaling pathways in human hepatocellular carcinoma cells
    Lihong Xu
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Cancer Res 66:11859-68. 2006
    ..Thus, PPARdelta induces COX-2 expression and the COX-2-derived PGE(2) further activates PPARdelta via cPLA(2)alpha. Such an interaction forms a novel feed-forward growth-promoting signaling that may play a role in hepatocarcinogenesis...
  8. ncbi request reprint Cyclooxygenase-2 promotes hepatocellular carcinoma cell growth through Akt activation: evidence for Akt inhibition in celecoxib-induced apoptosis
    Jing Leng
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Hepatology 38:756-68. 2003
    ..01). In conclusion, our results suggest the involvement of COX-2-dependent and -independent mechanisms in celecoxib-mediated HCC cell apoptosis...
  9. ncbi request reprint 85-kDa cytosolic phospholipase A2 mediates peroxisome proliferator-activated receptor gamma activation in human lung epithelial cells
    Rafal Pawliczak
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Biol Chem 277:33153-63. 2002
    ..The above results demonstrate a novel function of cPLA(2) in the control of PPARgamma activation in human lung epithelial cells...
  10. doi request reprint Evolution of the immunosuppressive strategies for the intestinal and multivisceral recipients with special reference to allograft immunity and achievement of partial tolerance
    Kareem M Abu-Elmagd
    Intestinal Rehabilitation and Transplantation Center, Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, PA, USA
    Transpl Int 22:96-109. 2009
    ....
  11. ncbi request reprint A novel positive feedback loop between peroxisome proliferator-activated receptor-delta and prostaglandin E2 signaling pathways for human cholangiocarcinoma cell growth
    Lihong Xu
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Biol Chem 281:33982-96. 2006
    ..This positive feedback loop plays an important role for cholangiocarcinoma cell growth and may be targeted for chemoprevention and treatment...
  12. ncbi request reprint Cyclooxygenase-2 promotes human cholangiocarcinoma growth: evidence for cyclooxygenase-2-independent mechanism in celecoxib-mediated induction of p21waf1/cip1 and p27kip1 and cell cycle arrest
    Chang Han
    Department of Pathology, University of Pittsburgh School of Medicine, Presbyterian University Hospital, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Cancer Res 64:1369-76. 2004
    ....
  13. doi request reprint Lymphoproliferative disorders and de novo malignancies in intestinal and multivisceral recipients: improved outcomes with new outlooks
    Kareem M Abu-Elmagd
    Department of Surgery, Thomas E Starzl Transplant Institute, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Transplantation 88:926-34. 2009
    ..To improve outcome, innovative management and immunosuppressant strategies were sequentially evolved...
  14. doi request reprint Cyclooxygenase-2-derived prostaglandin E2 activates beta-catenin in human cholangiocarcinoma cells: evidence for inhibition of these signaling pathways by omega 3 polyunsaturated fatty acids
    Kyu Lim
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Cancer Res 68:553-60. 2008
    ..Thus, utilization of omega 3-PUFAs may represent an effective and safe therapeutic approach for the chemoprevention and treatment of human cholangiocarcinoma...
  15. ncbi request reprint Modulation of Stat3 activation by the cytosolic phospholipase A2alpha and cyclooxygenase-2-controlled prostaglandin E2 signaling pathway
    Chang Han
    Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Biol Chem 281:24831-46. 2006
    ..DNA binding complex and that activation of EP(1) receptor in the nuclei enhances Stat3 activation depicts a previously undescribed G protein-coupled receptor in the nucleus for Stat3 activation and tumor cell growth...
  16. pmc Transgenic expression of cyclooxygenase-2 in hepatocytes accelerates endotoxin-induced acute liver failure
    Chang Han
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    J Immunol 181:8027-35. 2008
    ..Therefore, blocking COX-2-EP(1) pathway may represent a potential approach for amelioration of LPS-induced liver injury...
  17. pmc Regulation of Wnt/beta-catenin pathway by cPLA2alpha and PPARdelta
    Chang Han
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Cell Biochem 105:534-45. 2008
    ..These results depict a novel interaction linking cPLA(2)alpha, PPARdelta and Wnt/beta-catenin signaling pathways and provide insight for further understanding the roles of these key molecules in human cells and diseases...
  18. pmc Cyclooxygenase-2 prevents fas-induced liver injury through up-regulation of epidermal growth factor receptor
    Guiying Li
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Hepatology 50:834-43. 2009
    ..Conclusion: These findings demonstrate that COX-2 prevents Fas-induced hepatocyte apoptosis and liver failure at least in part through up-regulation of EGFR...
  19. doi request reprint Monitoring of human liver and kidney allograft tolerance: a tissue/histopathology perspective
    Anthony J Demetris
    Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, PA 15213, USA
    Transpl Int 22:120-41. 2009
    ....
  20. ncbi request reprint PPARgamma ligands inhibit cholangiocarcinoma cell growth through p53-dependent GADD45 and p21 pathway
    Chang Han
    Department of Pathology, Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Hepatology 38:167-77. 2003
    ....
  21. pmc Omega-3 polyunsaturated fatty acids inhibit hepatocellular carcinoma cell growth through blocking beta-catenin and cyclooxygenase-2
    Kyu Lim
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Mol Cancer Ther 8:3046-55. 2009
    ..These findings provide important preclinical evidence and molecular insight for utilization of omega-3 PUFAs for the chemoprevention and treatment of human HCC...
  22. doi request reprint Five hundred intestinal and multivisceral transplantations at a single center: major advances with new challenges
    Kareem M Abu-Elmagd
    Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Ann Surg 250:567-81. 2009
    ..To assess the evolution of visceral transplantation in the milieu of surgical technical modifications, new immunosuppressive protocols, and other management strategies...
  23. ncbi request reprint 85-kDa cPLA(2) plays a critical role in PPAR-mediated gene transcription in human hepatoma cells
    Chang Han
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Am J Physiol Gastrointest Liver Physiol 282:G586-97. 2002
    ..The cPLA(2) thus may represent a potential therapeutic target for the control of PPAR-related liver and metabolic disorders such as obesity, lipid metabolic disorders, diabetes mellitus, and atherosclerosis...
  24. ncbi request reprint Cyclooxygenase-2-derived prostaglandin E2 promotes human cholangiocarcinoma cell growth and invasion through EP1 receptor-mediated activation of the epidermal growth factor receptor and Akt
    Chang Han
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Biol Chem 280:24053-63. 2005
    ..This study reveals a novel cross-talk between the EP1 receptor and EGFR signaling that synergistically promotes cancer cell growth and invasion...
  25. ncbi request reprint Activation of cytosolic phospholipase A2alpha through nitric oxide-induced S-nitrosylation. Involvement of inducible nitric-oxide synthase and cyclooxygenase-2
    Lihong Xu
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Biol Chem 283:3077-87. 2008
    ..Therefore, therapy aimed at disrupting this interplay may represent a promising strategy to effectively inhibit PGE(2) production and prevent inflammation and carcinogenesis...
  26. pmc Cytosolic phospholipase A(2)α protects against Fas- but not LPS-induced liver injury
    Guiying Li
    Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, Jilin University, Changchun 130021, China
    J Hepatol 55:1281-90. 2011
    ..This study was designed to explore the role of hepatocyte cPLA(2)α in Fas-mediated liver injury, in vivo...
  27. ncbi request reprint Histopathologic characteristics of human intestine allograft acute rejection in patients pretreated with thymoglobulin or alemtuzumab
    Tong Wu
    Department of Pathology, Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Am J Gastroenterol 101:1617-24. 2006
    ....
  28. pmc Small proline-rich proteins (SPRR) function as SH3 domain ligands, increase resistance to injury and are associated with epithelial-mesenchymal transition (EMT) in cholangiocytes
    Anthony J Demetris
    Thomas E Starzl Transplantation Institute, Division of Transplantation, University of Pittsburgh Medical Center, UPMC Montefiore, Room E741, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    J Hepatol 48:276-88. 2008
    ..Since the function of SPRR in these circumstances is unknown, we tested the exploratory hypothesis that BEC SPRR2A expression contributes to BEC barrier function and wound repair...
  29. pmc Liver-specific beta-catenin knockout mice exhibit defective bile acid and cholesterol homeostasis and increased susceptibility to diet-induced steatohepatitis
    Jaideep Behari
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Pathol 176:744-53. 2010
    ..Therefore, loss of beta-catenin in the liver leads to defective cholesterol and bile acid metabolism in the liver and increased susceptibility to developing steatohepatitis in the face of metabolic stress...
  30. doi request reprint Endoscopic evaluation of small intestine transplant grafts
    STEPHEN J O'KEEFE
    Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Pittsburgh Medical School, Pittsburgh, PA, USA
    Transplantation 94:757-62. 2012
    ..The aim of this study was to evaluate the accuracy of endoscopic appearance in assessing histologic evidence of acute cellular rejection (ACR)...
  31. ncbi request reprint Cyclooxygenase-2 in hepatocellular carcinoma
    Tong Wu
    Department of Pathology, University of Pittsburgh School of Medicine, MUH E 740, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Cancer Treat Rev 32:28-44. 2006
    ..Understanding these mechanisms and interplays will facilitate the development of more effective chemopreventive and therapeutic strategies...
  32. ncbi request reprint A clinicopathologic study of isolated intestinal allografts with preformed IgG lymphocytotoxic antibodies
    Tong Wu
    Department of Pathology, Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, PA 15213, USA
    Hum Pathol 35:1332-9. 2004
    ..If recognized and treated aggressively, early graft failure can be avoided. The long-term significance of these preformed antibodies has yet to be determined...
  33. pmc Alpha-1 adrenergic receptor transactivates signal transducer and activator of transcription-3 (Stat3) through activation of Src and epidermal growth factor receptor (EGFR) in hepatocytes
    Chang Han
    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Cell Physiol 216:486-97. 2008
    ..Taken together, these observations demonstrate a novel alpha(1)-AR-mediated Stat3 activation that involves G(q/11), Src, and EGFR in hepatic cells...
  34. ncbi request reprint Hydrodynamic plasmid DNA gene therapy model in liver transplantation
    George Tsoulfas
    Department of Surgery, T E Starzl Transplantation Institute, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Surg Res 135:242-9. 2006
    ..Therefore, the purpose of this study was to develop a model of nonviral gene transfer in the liver transplant setting, allowing for efficient transgene expression...
  35. ncbi request reprint Cyclooxygenase-2 and prostaglandin signaling in cholangiocarcinoma
    Tong Wu
    Department of Pathology, University of Pittsburgh School of Medicine, MUH E 740, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Biochim Biophys Acta 1755:135-50. 2005
    ..Knowledge on these aspects will help develop more effective therapeutic strategy targeting COX-2 and related key signaling molecules...
  36. ncbi request reprint Urogenital disorders associated with gut failure and intestinal transplantation
    Ardavan Akhavan
    University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Urol 178:2067-72. 2007
    ..To our knowledge this study is the first to address such an important clinical observation with special reference to the underlying disease...
  37. doi request reprint Posttransplant adenoviral enteropathy in patients with small bowel transplantation
    Oyedele A Adeyi
    Department of Pathology, University of Pittsburgh Medical Center, Presbyterian Hospital, Pittsburgh, PA, USA
    Arch Pathol Lab Med 132:703-5. 2008
    ..The identification of characteristic viral inclusions in the surface or crypt epithelium points to the diagnosis of adenoviral enteropathy, in spite of the increased crypt apoptosis...
  38. ncbi request reprint Minimal evidence of transdifferentiation from recipient bone marrow to parenchymal cells in regenerating and long-surviving human allografts
    Tong Wu
    Division of Transplant Pathology, Thomas E Starzl Transplant Institute, University of Pittsburgh Medical Center, Pittsburgh, Pittsburgh, PA, USA
    Am J Transplant 3:1173-81. 2003
    ..Because of the extremely low frequency, interpretation was difficult. Regardless of these results, a more vigorous search for conditions that promote transdifferentiation is warranted...
  39. doi request reprint Renal cell carcinoma from a transplanted allograft: two case reports and a review of the literature
    Wassim McHayleh
    Department of Medicine, Division of Medical Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15232, USA
    Clin Genitourin Cancer 6:53-5. 2008
    ..Treatments in patients with disease confined to the kidney have included partial nephrectomy and total nephrectomy. A literature search did not find any reports of treatment of metastatic RCC that arose from a renal allograft...
  40. pmc p38-MAPK- and caspase-3-mediated superoxide-induced apoptosis of rat hepatic stellate cells: reversal by retinoic acid
    Noor Mohamed Jameel
    Department of Surgery, Thomas E Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, Pennsylvania
    J Cell Physiol 218:157-66. 2009
    ..These results suggest that the absence of retinoids render aHSCs susceptible to superoxide-induced apoptosis via caspase-3 and p38-MAPK activation...
  41. ncbi request reprint Inflammatory pseudotumor of the liver associated with Crohn's disease
    Georgios I Papachristou
    Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    J Clin Gastroenterol 38:818-22. 2004
    ..Following treatment of Crohn's disease, there was significant improvement in their overall clinical status. An underlying diagnosis of inflammatory bowel disease should be considered in patients with IPT...
  42. pmc Beta-catenin activation promotes liver regeneration after acetaminophen-induced injury
    Udayan Apte
    Division of Experimental Pathology, University of Pittsburgh School of Medicine, 200 Lothrop Street S 421 BST, Pittsburgh, PA 15261, USA
    Am J Pathol 175:1056-65. 2009
    ..Thus, our studies demonstrate early activation of beta-catenin signaling during acetaminophen-induced injury, which contributes to hepatic regeneration...
  43. ncbi request reprint De novo malignancies after intestinal and multivisceral transplantation
    Kareem M Abu-Elmagd
    Thomas E Starzl Transplantation Institute, Pittsburgh, PA 15213, USA
    Transplantation 77:1719-25. 2004
    ..With more than a decade of clinical experience, this report is the first to address the risk of de novo cancer after intestinal transplantation...
  44. pmc Tolerogenic immunosuppression for organ transplantation
    Thomas E Starzl
    Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Lancet 361:1502-10. 2003
    ..We aimed to apply these principles in recipients of renal and extrarenal organ transplants...
  45. ncbi request reprint Role of NF-kappaB on liver cold ischemia-reperfusion injury
    Yoshihito Takahashi
    Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Am J Physiol Gastrointest Liver Physiol 283:G1175-84. 2002
    ..Thus inhibition of the second wave of NF-kappaB activation in IkappaB-transfected livers resulted in an increase of liver injury, suggesting that NF-kappaB may have a dual role during liver I/R injury...
  46. ncbi request reprint Conditioning including antithymocyte globulin followed by unmanipulated HLA-mismatched/haploidentical blood and marrow transplantation can achieve comparable outcomes with HLA-identical sibling transplantation
    Dao Pei Lu
    Peking University Institute of Hematology, 11 Xizhimen South Street, Beijing 100044, China
    Blood 107:3065-73. 2006
    ..In summary, HCT performed with related HLA-mismatched donors is a feasible approach with acceptable outcomes...
  47. ncbi request reprint The role of TFIID, the initiator element and a novel 5' TFIID binding site in the transcriptional control of the TATA-less human cytosolic phospholipase A2-alpha promoter
    Mark J Cowan
    Division of Pulmonary and Critical Care Medicine, The University of Maryland, 10 North Greene Street, Room 3D 127, Baltimore, MD 21201, USA
    Biochim Biophys Acta 1680:145-57. 2004
    ..Finally, this study describes a novel AAGGAG motif at -30 to -35 which is bound by TATA-box binding protein (TBP) and is critical for basal transcriptional activity...
  48. ncbi request reprint [Mismatched hematopoietic stem cell transplantation using GIAC protocol: report of 100 cases]
    Wei Han
    Institute of Hematology, People s Hospital, Peking University, Beijing 100044, China
    Zhonghua Xue Ye Xue Za Zhi 25:453-7. 2004
    ..To explore the clinical application of human leukocyte antigen (HLA) mismatched hematopoietic stem cell transplantation (HSCT) for malignant hematological diseases using a new GIAC protocol...
  49. ncbi request reprint Cytosolic phospholipase A2 Group IValpha but not secreted phospholipase A2 Group IIA, V, or X induces interleukin-8 and cyclooxygenase-2 gene and protein expression through peroxisome proliferator-activated receptors gamma 1 and 2 in human lung cells
    Rafal Pawliczak
    Critical Care Medicine Department, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 279:48550-61. 2004
    ..These results demonstrate that cPLA2 has an influence on IL-8 and COX 2 gene and protein expression at least in part through PPAR-gamma...
  50. ncbi request reprint CD3+ cell dose and disease status are important factors determining clinical outcomes in patients undergoing unmanipulated haploidentical blood and marrow transplantation after conditioning including antithymocyte globulin
    Lujia Dong
    Peking University, People s Hospital, Beijing, China
    Biol Blood Marrow Transplant 13:1515-24. 2007
    ....
  51. ncbi request reprint Liver biopsy interpretation for causes of late liver allograft dysfunction
    Anthony J Demetris
    Hepatology 44:489-501. 2006
    ..A discussion of differential diagnosis is also presented...
  52. ncbi request reprint A case of montelukast-induced hepatotoxicity
    David A Sass
    Am J Gastroenterol 98:704-5. 2003
  53. ncbi request reprint Enhanced expression of uridine diphosphate-N-acetylglucosaminyl transferase (OGT) in a stable, tetracycline-inducible HeLa cell line using histone deacetylase inhibitors: kinetics of cytosolic OGT accumulation and nuclear translocation
    Stephen Marshall
    Hexos, Inc, Woodinville, WA 98072, USA
    Anal Biochem 319:304-13. 2003
    ....
  54. ncbi request reprint IcsA, a polarly localized autotransporter with an atypical signal peptide, uses the Sec apparatus for secretion, although the Sec apparatus is circumferentially distributed
    Lauren D Brandon
    Division of Infectious Diseases, Massachusetts General Hospital, Cambridge, MA 02139, USA
    Mol Microbiol 50:45-60. 2003
    ..Based on these data, we propose a model for coordinate polar targeting and secretion of IcsA at the bacterial pole...
  55. ncbi request reprint [Allogeneic hematopoietic stem cell transplantation for acute lymphocytic leukemia]
    Huan Chen
    Institute of Hematology, People s Hospital, Peking University, Beijing 100044, China
    Zhonghua Xue Ye Xue Za Zhi 25:87-90. 2004
    ..To retrospectively analyze the results of a consecutive series of 100 ALL patients received allogeneic hematopoietic stem cell transplantation (allo-HSCT) in our center...
  56. ncbi request reprint Congenital hepatic fibrosis: CT findings in 18 adults
    Delphine Zeitoun
    Department of Radiology, Hopital Beaujon, Clichy, France
    Radiology 231:109-16. 2004
    ..To evaluate the computed tomographic (CT) findings in adult patients with pathologically proved congenital hepatic fibrosis...
  57. ncbi request reprint [Increasingly improving outcomes of allogeneic hematopoietic cell transplantation]
    Wan Ming DA
    Zhonghua Xue Ye Xue Za Zhi 27:505-6. 2006
  58. ncbi request reprint Cloning, characterization and subcellular localization of a gene encoding a human Ubiquitin-conjugating enzyme (E2) homologous to the Arabidopsis thaliana UBC-16 gene product
    Gang Yin
    State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, 200433, P R China
    Front Biosci 11:1500-7. 2006
    ....